Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling

Molecular and Cellular Endocrinology

Volumn 400, Issue , 2015, Pages 112-128

  Kapodistria, Katerina ^a   Tsilibary, Effie Photini ^a   Politis, Panagiotis ^b   Moustardas, Petros ^b   Charonis, Aristidis ^b   Kitsiou, Paraskevi ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b Academy of Athens Biomedical Research Foundation   (Greece)

Author keywords

Diabetic mouse pancreatic islets; High glucose; Nephrin internalization; Nephrin signaling; Pancreatic cells; PI3K Akt survival signaling

Indexed keywords

GLUCOSE; NEPHRIN; NEPHRIN ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ANTIBODY; PROTEIN BAD; PROTEIN KINASE B; PROTEIN KINASE C; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG; BAD PROTEIN, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; INSULIN; LEPTIN RECEPTOR; LEPTIN RECEPTOR, MOUSE; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PROTEIN KINASE C ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; CELL MEMBRANE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME REGULATION; GENE SILENCING; INHIBITION KINETICS; INTERNALIZATION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TRANSFORMED CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CELL LINE, TRANSFORMED; CELL MEMBRANE; CELL SURVIVAL; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, LEPTIN; SIGNAL TRANSDUCTION;

EID: 84914162444     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2014.11.003     Document Type: Article

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