Nephrin is expressed in the pancreatic beta cells

Diabetologia

Volumn 44, Issue 10, 2001, Pages 1274-1280

  Palmen T ^a   Ahola, H ^a   Palgi, J ^b   Aaltonen, P ^a   Luimula, P ^a   Wang, S ^a   Jaakkola, I ^c   Knip, M ^b   Otonkoski, T ^b   Holthofer H ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

Beta cell; Immunoglobulin superfamily; Islets of Langerhans; Nephrin; NPHS1 gene

Indexed keywords

COMPLEMENTARY DNA; NEPHRIN; RNA;

ARTICLE; CADAVER; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; KIDNEY; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION;

CADAVER; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; GENE EXPRESSION; GLUCAGON; HUMANS; IMMUNOBLOTTING; ISLETS OF LANGERHANS; KERATINS; KIDNEY; KIDNEY CORTEX; MEMBRANE PROTEINS; MOLECULAR WEIGHT; PANCREAS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SOMATOSTATIN;

EID: 0034775038     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250100641     Document Type: Article

References (23)

1. Congenital nephrotic syndrome
2. Management of congenital nephrotic syndrome of the Finnish type
3. Congenital nephrotic syndrome of the Finnish type maps to the long arm of chromosome 19
4. Fine mapping and haplotype analysis of the locus for congenital nephrotic syndrome on chromosome 19q13.1
5. Positionally cloned gene for a novel glomerular protein - Nephrin - Is mutated in congenital nephrotic syndrome
6. Structure of the gene for congenital nephrotic syndrome of the Finnish type (NPHS1) and characterization of mutations
7. Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney
8. Cloning and expression of the rat nephrin homolog
9. Nephrin localizes to the slit pore of the glomerular epithelial cell
10. Nephrin is specifically located at the slit diaphragm of glomerular podocytes
11. Glomerular expression of nephrin is decreased in acquired human nephrotic syndrome
12. Nephrin in experimental glomerular disease
13. Alternatively spliced nephrin in experimental glomerular disease of the rat
14. The murine nephrin gene is specifically expressed in kidney, brain and pancreas
15. Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins
16. Immunocytochemical localization of the Heymann nephritis antigen (gp 330) in glomerular epithelial cells of normal Lewis rats
17. Alternative splicing generates a secreted form of N-CAM in muscle and brain
18. Acute myoblastic leukaemia cells produce soluble interleukin 6 receptor by mechanism of alternative splicing
19. Molecular cloning of pTAC12 an alternative splicing product of the CD3γ chain as a component of the pre-T cell antigen receptor complex
20. The immunoglobulin superfamily
21. Unraveling the mechanisms of glomerular ultrafiltration: Nephrin, a key component of the slit diaphragm
22. Discovery of the congenital nephrotic syndrome gene discloses the structure of the mysterious molecular sieve of the kidney
23. Congenital nephrotic syndrome in mice lacking CD2-associated protein