Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease

Journal of Clinical Investigation

Volumn 122, Issue 2, 2012, Pages 674-692

  George, Britta ^a   Verma, Rakesh ^b   Soofi, Abdulsalam A ^b   Garg, Puneet ^b   Zhang, Jidong ^a   Park, Tae Ju ^c   Giardino, Laura ^d   Ryzhova, Larisa ^e   Johnstone, Duncan B ^a   Wong, Hetty ^a   Nihalani, Deepak ^a   Salant, David J ^f   Hanks, Steven K ^e   Curran, Tom ^c   Rastaldi, Maria Pia ^d   Holzman, Lawrence B ^a,g  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; FOCAL ADHESION KINASE; NEPHRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTAMINE SULFATE; PROTEIN CRK1; PROTEIN CRK2; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; COMPLEX FORMATION; CONTROLLED STUDY; FOCAL GLOMERULOSCLEROSIS; GENE DELETION; GLOMERULOPATHY; HUMAN; HUMAN CELL; IN VIVO STUDY; LAMELLIPODIUM; MALE; MEMBRANOUS GLOMERULONEPHRITIS; MOUSE; NONHUMAN; PHENOTYPE; PODOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEINURIA; SIGNAL TRANSDUCTION;

ADOLESCENT; ADULT; AGED; ANIMALS; CELL LINE; CRK-ASSOCIATED SUBSTRATE PROTEIN; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; KIDNEY DISEASES; KIDNEY GLOMERULUS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASES; PODOCYTES; PROTO-ONCOGENE PROTEINS C-CRK; PSEUDOPODIA; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84863066779     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI60070     Document Type: Article

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