Moving through three-dimensional phase diagrams of monoclonal antibodies

Biotechnology Progress

Volumn 30, Issue 5, 2014, Pages 1103-1113

  Rakel, Natalie ^a   Baum, Miriam ^a   Hubbuch, Jürgen ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

High throughput screening; Protein phase behavior, phase diagram, monoclonal antibody, crystallization

Indexed keywords

MONOCLONAL ANTIBODIES; PHASE BEHAVIOR; PHASE DIAGRAMS; SALTS;

HIGH THROUGHPUT SCREENING; HOFMEISTER SERIES; INFLUENCE OF FLUID; INFLUENCING PARAMETERS; PARAMETER RANGE; SALT CONCENTRATION; SCREENING METHODS;

PRECIPITATION (CHEMICAL);

ION; MONOCLONAL ANTIBODY; PROTEIN AGGREGATE; SODIUM CHLORIDE; SULFATE;

BIOTECHNOLOGY; CHEMISTRY; CRYSTALLIZATION; DRUG EFFECTS; HIGH THROUGHPUT SCREENING; METABOLISM; METHODOLOGY; PH; PROCEDURES;

ANTIBODIES, MONOCLONAL; BIOTECHNOLOGY; CRYSTALLIZATION; HIGH-THROUGHPUT SCREENING ASSAYS; HYDROGEN-ION CONCENTRATION; IONS; PROTEIN AGGREGATES; RESEARCH DESIGN; SODIUM CHLORIDE; SULFATES;

EID: 84914142019     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1947     Document Type: Article

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