Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Aβ peptides associated with Alzheimer's disease

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 64, Issue 5, 2008, Pages 438-441

  Wun, Kwok S ^a,g   Miles, Luke A ^a,b,c   Crespi, Gabriela A N ^a   Wycherley, Kaye ^d   Ascher, David B ^a   Barnham, Kevin J ^b,c,e   Cappai, Roberto ^b,c,e   Beyreuther, Konrad ^f   Masters, Colin L ^b,e   Parker, Michael W ^a,c   McKinstry, William J ^a,b,h  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^f UNIVERSITY OF HEIDELBERG   (Germany)

^g MONASH UNIVERSITY   (Australia)

^h PFIZER INC   (United States)

Author keywords

A peptides; Alzheimer's disease; Antibody Fab fragments; Immunotherapy

Indexed keywords

AMYLOID BETA PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ARTICLE; CHEMISTRY; CRYSTALLIZATION; HUMAN; IMMUNOLOGY; X RAY DIFFRACTION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANTIBODIES, MONOCLONAL; CRYSTALLIZATION; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; PEPTIDE FRAGMENTS; X-RAY DIFFRACTION;

MURINAE;

EID: 43049084055     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309108011718     Document Type: Article

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