-
1
-
-
77956636819
-
Low-frequency wide-field fluorescence lifetime imaging using a high-power near-infrared light-emitting diode light source
-
Gioux, S., Lomnes, S. J., Choi, H. S., and Frangioni, J. V. (2010) Low-frequency wide-field fluorescence lifetime imaging using a high-power near-infrared light-emitting diode light source J. Biomed. Opt. 15, 026005
-
(2010)
J. Biomed. Opt.
, vol.15
, pp. 026005
-
-
Gioux, S.1
Lomnes, S.J.2
Choi, H.S.3
Frangioni, J.V.4
-
2
-
-
84875841161
-
Fluorescence imaging in surgery
-
Orosco, R. K., Tsien, R. Y., and Nguyen, Q. T. (2013) Fluorescence imaging in surgery IEEE Rev. Biomed. Eng. 6, 178-187
-
(2013)
IEEE Rev. Biomed. Eng.
, vol.6
, pp. 178-187
-
-
Orosco, R.K.1
Tsien, R.Y.2
Nguyen, Q.T.3
-
3
-
-
84883192924
-
Fluorescence-guided surgery with live molecular navigation-A new cutting edge
-
Nguyen, Q. T. and Tsien, R. Y. (2013) Fluorescence-guided surgery with live molecular navigation-A new cutting edge Nat. Rev. Cancer 13, 653-662
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 653-662
-
-
Nguyen, Q.T.1
Tsien, R.Y.2
-
4
-
-
84856544369
-
Translational genomics: The challenge of developing cancer biomarkers
-
Brooks, J. D. (2012) Translational genomics: The challenge of developing cancer biomarkers Genome Res. 22, 183-187
-
(2012)
Genome Res.
, vol.22
, pp. 183-187
-
-
Brooks, J.D.1
-
5
-
-
84876020428
-
Family of pH (low) insertion peptides for tumor targeting
-
Weerakkody, D., Moshnikova, A., Thakur, M. S., Moshnikova, V., Daniels, J., Engelman, D. M., Andreev, O. A., and Reshetnyak, Y. K. (2013) Family of pH (low) insertion peptides for tumor targeting Proc. Natl. Acad. Sci. U.S.A. 110, 5834-5839
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 5834-5839
-
-
Weerakkody, D.1
Moshnikova, A.2
Thakur, M.S.3
Moshnikova, V.4
Daniels, J.5
Engelman, D.M.6
Andreev, O.A.7
Reshetnyak, Y.K.8
-
6
-
-
0029971428
-
Cellular pH gradient in tumor versus normal tissue: Potential exploitation for the treatment of cancer
-
Gerweck, L. E. and Seetharaman, K. (1996) Cellular pH gradient in tumor versus normal tissue: Potential exploitation for the treatment of cancer Cancer Res. 56, 1194-1198
-
(1996)
Cancer Res.
, vol.56
, pp. 1194-1198
-
-
Gerweck, L.E.1
Seetharaman, K.2
-
7
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. (1956) On the origin of cancer cells Science 123, 309-314
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
8
-
-
77956212249
-
Tumor pH and its measurement
-
Zhang, X., Lin, Y., and Gillies, R. J. (2010) Tumor pH and its measurement J. Nucl. Med. 51, 1167-1170
-
(2010)
J. Nucl. Med.
, vol.51
, pp. 1167-1170
-
-
Zhang, X.1
Lin, Y.2
Gillies, R.J.3
-
9
-
-
0024379967
-
Acid pH in tumors and its potential for therapeutic exploitation
-
Tannock, I. F. and Rotin, D. (1989) Acid pH in tumors and its potential for therapeutic exploitation Cancer Res. 49, 4373-4384
-
(1989)
Cancer Res.
, vol.49
, pp. 4373-4384
-
-
Tannock, I.F.1
Rotin, D.2
-
10
-
-
84874886049
-
Acidity generated by the tumor microenvironment drives local invasion
-
Estrella, V., Chen, T., Lloyd, M., Wojtkowiak, J., Cornnell, H. H., Ibrahim-Hashim, A., Bailey, K., Balagurunathan, Y., Rothberg, J. M., Sloane, B. F., Johnson, J., Gatenby, R. A., and Gillies, R. J. (2013) Acidity generated by the tumor microenvironment drives local invasion Cancer Res. 73, 1524-1535
-
(2013)
Cancer Res.
, vol.73
, pp. 1524-1535
-
-
Estrella, V.1
Chen, T.2
Lloyd, M.3
Wojtkowiak, J.4
Cornnell, H.H.5
Ibrahim-Hashim, A.6
Bailey, K.7
Balagurunathan, Y.8
Rothberg, J.M.9
Sloane, B.F.10
Johnson, J.11
Gatenby, R.A.12
Gillies, R.J.13
-
11
-
-
77953935500
-
Tumor hypoxia induces a metabolic shift causing acidosis: A common feature in cancer
-
Chiche, J., Brahimi-Horn, M. C., and Pouyssegur, J. (2010) Tumor hypoxia induces a metabolic shift causing acidosis: A common feature in cancer J. Cell Mol. Med. 14, 771-794
-
(2010)
J. Cell Mol. Med.
, vol.14
, pp. 771-794
-
-
Chiche, J.1
Brahimi-Horn, M.C.2
Pouyssegur, J.3
-
12
-
-
55749112330
-
Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane
-
Reshetnyak, Y. K., Andreev, O. A., Segala, M., Markin, V. S., and Engelman, D. M. (2008) Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane Proc. Natl. Acad. Sci. U.S.A. 105, 15340-15345
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 15340-15345
-
-
Reshetnyak, Y.K.1
Andreev, O.A.2
Segala, M.3
Markin, V.S.4
Engelman, D.M.5
-
13
-
-
34848885103
-
A monomeric membrane peptide that lives in three worlds: In solution, attached to, and inserted across lipid bilayers
-
Reshetnyak, Y. K., Segala, M., Andreev, O. A., and Engelman, D. M. (2007) A monomeric membrane peptide that lives in three worlds: In solution, attached to, and inserted across lipid bilayers Biophys. J. 93, 2363-2372
-
(2007)
Biophys. J.
, vol.93
, pp. 2363-2372
-
-
Reshetnyak, Y.K.1
Segala, M.2
Andreev, O.A.3
Engelman, D.M.4
-
14
-
-
34249949775
-
Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo
-
Andreev, O. A., Dupuy, A. D., Segala, M., Sandugu, S., Serra, D. A., Chichester, C. O., Engelman, D. M., and Reshetnyak, Y. K. (2007) Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo Proc. Natl. Acad. Sci. U.S.A. 104, 7893-7898
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 7893-7898
-
-
Andreev, O.A.1
Dupuy, A.D.2
Segala, M.3
Sandugu, S.4
Serra, D.A.5
Chichester, C.O.6
Engelman, D.M.7
Reshetnyak, Y.K.8
-
15
-
-
69549108017
-
Accurate analysis of tumor margins using a fluorescent pH Low Insertion Peptide (pHLIP)
-
Segala, J., Engelman, D. M., Reshetnyak, Y. K., and Andreev, O. A. (2009) Accurate analysis of tumor margins using a fluorescent pH Low Insertion Peptide (pHLIP) Int. J. Mol. Sci. 10, 3478-3487
-
(2009)
Int. J. Mol. Sci.
, vol.10
, pp. 3478-3487
-
-
Segala, J.1
Engelman, D.M.2
Reshetnyak, Y.K.3
Andreev, O.A.4
-
16
-
-
84897879624
-
Targeting pancreatic ductal adenocarcinoma acidic microenvironment
-
Cruz-Monserrate, Z., Roland, C. L., Deng, D., Arumugam, T., Moshnikova, A., Andreev, O. A., Reshetnyak, Y. K., and Logsdon, C. D. (2014) Targeting pancreatic ductal adenocarcinoma acidic microenvironment Sci. Rep. 4, 4410
-
(2014)
Sci. Rep.
, vol.4
, pp. 4410
-
-
Cruz-Monserrate, Z.1
Roland, C.L.2
Deng, D.3
Arumugam, T.4
Moshnikova, A.5
Andreev, O.A.6
Reshetnyak, Y.K.7
Logsdon, C.D.8
-
17
-
-
66249099231
-
A novel technology for the imaging of acidic prostate tumors by positron emission tomography
-
Vavere, A. L., Biddlecombe, G. B., Spees, W. M., Garbow, J. R., Wijesinghe, D., Andreev, O. A., Engelman, D. M., Reshetnyak, Y. K., and Lewis, J. S. (2009) A novel technology for the imaging of acidic prostate tumors by positron emission tomography Cancer Res. 69, 4510-4516
-
(2009)
Cancer Res.
, vol.69
, pp. 4510-4516
-
-
Vavere, A.L.1
Biddlecombe, G.B.2
Spees, W.M.3
Garbow, J.R.4
Wijesinghe, D.5
Andreev, O.A.6
Engelman, D.M.7
Reshetnyak, Y.K.8
Lewis, J.S.9
-
18
-
-
84901036369
-
Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer
-
Viola-Villegas, N. T., Carlin, S. D., Ackerstaff, E., Sevak, K. K., Divilov, V., Serganova, I., Kruchevsky, N., Anderson, M., Blasberg, R. G., Andreev, O. A., Engelman, D. M., Koutcher, J. A., Reshetnyak, Y. K., and Lewis, J. S. (2014) Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer Proc. Natl. Acad. Sci. U.S.A. 111, 7254-7259
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 7254-7259
-
-
Viola-Villegas, N.T.1
Carlin, S.D.2
Ackerstaff, E.3
Sevak, K.K.4
Divilov, V.5
Serganova, I.6
Kruchevsky, N.7
Anderson, M.8
Blasberg, R.G.9
Andreev, O.A.10
Engelman, D.M.11
Koutcher, J.A.12
Reshetnyak, Y.K.13
Lewis, J.S.14
-
19
-
-
33646272211
-
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix
-
Reshetnyak, Y. K., Andreev, O. A., Lehnert, U., and Engelman, D. M. (2006) Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix Proc. Natl. Acad. Sci. U.S.A. 103, 6460-6465
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 6460-6465
-
-
Reshetnyak, Y.K.1
Andreev, O.A.2
Lehnert, U.3
Engelman, D.M.4
-
20
-
-
78650553199
-
PH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation
-
An, M., Wijesinghe, D., Andreev, O. A., Reshetnyak, Y. K., and Engelman, D. M. (2010) pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation Proc. Natl. Acad. Sci. U.S.A. 107, 20246-20250
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 20246-20250
-
-
An, M.1
Wijesinghe, D.2
Andreev, O.A.3
Reshetnyak, Y.K.4
Engelman, D.M.5
-
21
-
-
84874056993
-
Antiproliferative effect of pHLIP-amanitin
-
Moshnikova, A., Moshnikova, V., Andreev, O. A., and Reshetnyak, Y. K. (2013) Antiproliferative effect of pHLIP-amanitin Biochemistry 52, 1171-1178
-
(2013)
Biochemistry
, vol.52
, pp. 1171-1178
-
-
Moshnikova, A.1
Moshnikova, V.2
Andreev, O.A.3
Reshetnyak, Y.K.4
-
22
-
-
0018327389
-
Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver
-
Moron, M. S., Depierre, J. W., and Mannervik, B. (1979) Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver Biochim. Biophys. Acta 582, 67-78
-
(1979)
Biochim. Biophys. Acta
, vol.582
, pp. 67-78
-
-
Moron, M.S.1
Depierre, J.W.2
Mannervik, B.3
-
23
-
-
67650787319
-
H-type dimer formation of fluorophores: A mechanism for activatable, in vivo optical molecular imaging
-
Ogawa, M., Kosaka, N., Choyke, P. L., and Kobayashi, H. (2009) H-type dimer formation of fluorophores: A mechanism for activatable, in vivo optical molecular imaging ACS Chem. Biol. 4, 535-546
-
(2009)
ACS Chem. Biol.
, vol.4
, pp. 535-546
-
-
Ogawa, M.1
Kosaka, N.2
Choyke, P.L.3
Kobayashi, H.4
-
24
-
-
84855683946
-
Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP
-
Reshetnyak, Y. K., Yao, L., Zheng, S., Kuznetsov, S., Engelman, D. M., and Andreev, O. A. (2011) Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP Mol. Imaging Biol. 13, 1146-1156
-
(2011)
Mol. Imaging Biol.
, vol.13
, pp. 1146-1156
-
-
Reshetnyak, Y.K.1
Yao, L.2
Zheng, S.3
Kuznetsov, S.4
Engelman, D.M.5
Andreev, O.A.6
-
25
-
-
78049333901
-
PH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents
-
Andreev, O. A., Engelman, D. M., and Reshetnyak, Y. K. (2010) pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents Mol. Membr. Biol. 27, 341-352
-
(2010)
Mol. Membr. Biol.
, vol.27
, pp. 341-352
-
-
Andreev, O.A.1
Engelman, D.M.2
Reshetnyak, Y.K.3
-
26
-
-
0029670262
-
Molecular beacons: Probes that fluoresce upon hybridization
-
Tyagi, S. and Kramer, F. R. (1996) Molecular beacons: probes that fluoresce upon hybridization Nat. Biotechnol. 14, 303-308
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 303-308
-
-
Tyagi, S.1
Kramer, F.R.2
-
27
-
-
0037134940
-
Intramolecular dimers: A new strategy to fluorescence quenching in dual-labeled oligonucleotide probes
-
Johansson, M. K., Fidder, H., Dick, D., and Cook, R. M. (2002) Intramolecular dimers: A new strategy to fluorescence quenching in dual-labeled oligonucleotide probes J. Am. Chem. Soc. 124, 6950-6956
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 6950-6956
-
-
Johansson, M.K.1
Fidder, H.2
Dick, D.3
Cook, R.M.4
|