A validated HPLC-FLD method for analysis of intestinal absorption and metabolism of capsaicin and dihydrocapsaicin in the rat

Journal of Pharmaceutical and Biomedical Analysis

Volumn 103, Issue , 2015, Pages 59-66

  Kuzma, Mónika ^a   Fodor, Krisztina ^a   Maász, Gábor ^a   Avar, Péter ^a   Mózsik, Gyula ^a   Past, Tibor ^a   Fischer, Emil ^a   Perjési, Pál ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Capsaicin and dihydrocapsaicin; Fluorescent detection; Glucuronide metabolites; High performance liquid chromatography; Intestinal metabolism

Indexed keywords

ACETONITRILE; CAPSAICIN; DIHYDROCAPSAICIN; GLUCURONIDE; PEPPER EXTRACT; PHOSPHORIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CALIBRATION; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG METABOLISM; DRUG STRUCTURE; ELUTION; FLOW RATE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE ABSORPTION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; MASS SPECTROMETRY; NONHUMAN; PH; RAT; ROOM TEMPERATURE; SMALL INTESTINE; ANALOGS AND DERIVATIVES; ANIMAL; AREA UNDER THE CURVE; METABOLISM; PROCEDURES; REPRODUCIBILITY; SPECTROFLUOROMETRY; STANDARD; VALIDATION STUDY; WISTAR RAT;

ANIMALS; AREA UNDER CURVE; CALIBRATION; CAPSAICIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INTESTINAL ABSORPTION; LIMIT OF DETECTION; MALE; RATS; RATS, WISTAR; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, FLUORESCENCE;

EID: 84914129355     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2014.10.007     Document Type: Article

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