Immunosuppressive activity of capsaicinoids: Capsiate derived from sweet peppers inhibits NF-κB activation and is a potent antiinflammatory compound in vivo

European Journal of Immunology

Volumn 32, Issue 6, 2002, Pages 1753-1763

  Sancho, Rocío ^a   Lucena, Concepción ^a   Macho, Antonio ^a   Calzado, Marco A ^a   Blanco Molina, Magdalena ^a   Minassi, Alberto ^b   Appendino, Giovanni ^b   Muñoz, Eduardo ^a,c  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^c Universidad de Cordoba   (Spain)

Author keywords

Capsiate; Inflammatory bowel disease; NF B; Septic shock; T cell

Indexed keywords

ANTIINFLAMMATORY AGENT; CAPSAICIN; CAPSAICIN DERIVATIVE; CD28 ANTIGEN; CD69 ANTIGEN; CELL SURFACE MARKER; DIHYDROCAPSAICIN; DOCUSATE SODIUM; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2 RECEPTOR; LIPOPOLYSACCHARIDE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; OKT 3; OLIVE OIL; PROTEIN C JUN; PROTEIN KINASE; SYNAPTOPHYSIN; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; DRUG ACTIVITY; DRUG DEVELOPMENT; DRUG STRUCTURE; ENZYME ACTIVATION; GASTROINTESTINAL GLAND; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IN VIVO STUDY; INFLAMMATION; INTESTINE EPITHELIUM; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SEPTIC SHOCK; SWEET PEPPER; T LYMPHOCYTE ACTIVATION; TISSUE INJURY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAPSAICIN; CAPSICUM; DNA-BINDING PROTEINS; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; IMMUNOSUPPRESSIVE AGENTS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; T-LYMPHOCYTES; TRANS-ACTIVATION (GENETICS);

EID: 0036083634     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200206)32:6<1753::AID-IMMU1753>3.0.CO;2-2     Document Type: Article

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