Design, synthesis, and evaluation of caffeic acid amides as synergists to sensitize fluconazole-resistant Candida albicans to fluconazole

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 1, 2015, Pages 34-37

  Dai, Li ^a   Zang, Chengxu ^a   Tian, Shujuan ^a   Liu, Wei ^b   Tan, Shanlun ^a   Cai, Zhan ^a   Ni, Tingjunhong ^a   An, Maomao ^b   Li, Ran ^a   Gao, Yue ^a   Zhang, Dazhi ^a   Jiang, Yuanying ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Caffeic acid; Candida albicans; Fluconazole resistant; Structure activity relationship; Synergistic activity

Indexed keywords

AMIDE; CAFFEIC ACID; FLUCONAZOLE; CAFFEIC ACID DERIVATIVE;

ARTICLE; CANDIDA ALBICANS; DRUG DESIGN; DRUG POTENTIATION; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHARMACOPHORE; ANTIFUNGAL RESISTANCE; CHEMISTRY; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; PHYSIOLOGY; PROCEDURES;

CANDIDA ALBICANS;

AMIDES; CAFFEIC ACIDS; CANDIDA ALBICANS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, FUNGAL; DRUG SYNERGISM; FLUCONAZOLE; MICROBIAL SENSITIVITY TESTS;

EID: 84913557756     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.11.022     Document Type: Article

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