Synthesis, structure and structure-activity relationship analysis of caffeic acid amides as potential antimicrobials

European Journal of Medicinal Chemistry

Volumn 45, Issue 6, 2010, Pages 2638-2643

  Fu, Jie ^a   Cheng, Kui ^a   Zhang, Zhi ming ^a   Fang, Rui qin ^a   Zhu, Hai liang ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Antimicrobial activities; Caffeic acid amides; Structure activity relationship; Synthesis

Indexed keywords

3 (3,4 DIHYDROXYPHENYL) N (2 FLUOROPHENYL)ACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N (2 METHOXYPHENYL)ACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N (2 NITROPHENYL)ACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N (3 FLUOROPHENYL)ACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N (3 METHOXYPHENYL)ACRYLAMIDEZ; 3 (3,4 DIHYDROXYPHENYL) N (3 NITROPHENYL)ACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N (4 METHOXYPHENYL)ACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N (4 NITROPHENYL)ACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N 2 TOLYLACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N 3 TOLYLACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N 4 TOLYLACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N ETHYLACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N METHYL N PHENYLACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N PHENYLACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N,N DIETHYLACRYLAMIDE; 3 (3,4 DIHYDROXYPHENYL) N,N DIPHENYLACRYLAMIDE; 3 (4 HYDROXYPHENYL) N PHENYLACRYLAMIDE; AMIDE; ANTIINFECTIVE AGENT; BENZENE; CAFFEIC ACID DERIVATIVE; N (2 BROMOPHENYL) 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; N (2 CHLOROPHENYL) 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; N (3 BROMOPHENYL) 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; N (3 CHLOROPHENYL) 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; N (4 BROMOPHENYL) 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; N (4 CHLOROPHENYL) 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; N (4 FLUOROPHENYL) 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; N ETHYL 3 (4 HYDROXYPHENYL)ACRYLAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS SUBTILIS; CANDIDA ALBICANS; CHEMICAL BOND; CHEMICAL STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS FLUORESCENS; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; TRICHOPHYTON RUBRUM; X RAY DIFFRACTION;

AMIDES; ANTI-INFECTIVE AGENTS; BACTERIA; CAFFEIC ACIDS; CRYSTALLOGRAPHY, X-RAY; FUNGI; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77950858027     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.01.066     Document Type: Article

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