Double-negative feedback loop between ZEB2 and miR-145 regulates epithelial-mesenchymal transition and stem cell properties in prostate cancer cells

Cell and Tissue Research

Volumn 358, Issue 3, 2014, Pages 763-778

  Ren, Dong ^a   Wang, Min ^a   Guo, Wei ^a   Huang, Shuai ^a   Wang, Zeyu ^a   Zhao, Xiaohui ^b   Du, Hong ^c   Song, Libing ^b   Peng, Xinsheng ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c The First People's Hospital of Guangzhou City   (China)

Author keywords

Bone metastasis of prostate cancer; Cancer cell stemness; Epithelial mesenchymal transition; MicroRNAs; Zinc finger E box binding homeobox 2 (ZEB2)

Indexed keywords

MICRORNA 145; PROSTATE SPECIFIC ANTIGEN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER E BOX BINDING HOMEOBOX 2; HOMEODOMAIN PROTEIN; MICRORNA; MIRN145 MICRORNA, HUMAN; REPRESSOR PROTEIN; ZEB2 PROTEIN, HUMAN;

ARTICLE; BONE METASTASIS; CANCER PATIENT; CANCER STEM CELL; CARCINOGENESIS; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DU145 CELL LINE; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GLEASON SCORE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; NEGATIVE FEEDBACK; PC 3 CELL LINE; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; TUMOR INVASION; ANIMAL; BIOLOGICAL MODEL; BONE TUMOR; CELL MOTION; DRUG SCREENING; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MULTICELLULAR SPHEROID; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROSTATE TUMOR; SCID MOUSE; SECONDARY; TUMOR CELL LINE;

ANIMALS; BASE SEQUENCE; BONE NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICE, SCID; MICRORNAS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; PROSTATIC NEOPLASMS; REPRESSOR PROTEINS; SPHEROIDS, CELLULAR; TRANSCRIPTION, GENETIC; TUMOR STEM CELL ASSAY;

EID: 84912564981     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-014-2001-y     Document Type: Article

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