Neuroprotective Effect of N-Acyl 5-Hydroxytryptamines on Glutamate-Induced Cytotoxicity in HT-22 Cells

Neurochemical Research

Volumn 39, Issue 12, 2014, Pages 2440-2451

  Jin, Mei Chen ^a   Yoo, Jae Myung ^b   Sok, Dai Eun ^a   Kim, Mee Ree ^a  

^a Chungnam National University   (South Korea)

^b Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

Glutamate; HT 22 cells; MARK; N acyl 5 HT; Nrf2; Oxidative stress

Indexed keywords

GLUTAMATE CYSTEINE LIGASE; GLUTAMIC ACID; GLUTATHIONE; HEME OXYGENASE 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SEROTONIN; TRANSCRIPTION FACTOR NRF2; GLUTAMINE; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL COUNTING; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CELL LINE; HUMAN; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; GLUTAMINE; HUMANS; MAP KINASE SIGNALING SYSTEM; NEUROPROTECTIVE AGENTS; SEROTONIN;

EID: 84912564930     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1448-2     Document Type: Article

References (43)

1. Beal MF (1995) Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 38(3):357–366. doi:10.1002/ana.410380304
2. Atlante A, Calissano P, Bobba A, Giannattasio S, Marra E, Passarella S (2001) Glutamate neurotoxicity, oxidative stress and mitochondria. FEBS Lett 497(1):1–5. doi:10.1016/S0014-5793(01)02437-1
3. Newell DW, Barth A, Papermaster V, Malouf AT (1995) Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures. J Neurosci 15(11):7702–7711
4. Maher P, Davis JB (1996) The role of monoamine metabolism in oxidative glutamate toxicity. J Neurosci 16(20):6394–6401
5. Fu Y, Koo MW (2006) EGCG protects HT-22 cells against glutamate-induced oxidative stress. Neurotox Res 10(1):23–30
6. Poteet E, Winters A, Yan LJ, Shufelt K, Green KN, Simpkins JW, Wen Y, Yang SH (2012) Neuroprotective actions of methylene blue and its derivatives. PLoS One 7(10):e48279. doi:10.1371/journal.pone.0048279
7. Luo Y, DeFranco DB (2006) Opposing roles for ERK1/2 in neuronal oxidative toxicity: distinct mechanisms of ERK1/2 action at early versus late phases of oxidative stress. J Biol Chem 281(24):16436–16442. doi:10.1074/jbc.M512430200
8. Ha JS, Kwon KS, Park SS (2013) PI3Kgamma contributes to MEK1/2 activation in oxidative glutamate toxicity via PDK1. J Neurochem 127(1):139–148. doi:10.1111/jnc.12364
9. Sagara Y, Dargusch R, Chambers D, Davis J, Schubert D, Maher P (1998) Cellular mechanisms of resistance to chronic oxidative stress. Free Radic Biol Med 24(9):1375–1389. doi:10.1016/S0891-5849(97)00457-7
10. Rossler OG, Bauer I, Chung HY, Thiel G (2004) Glutamate-induced cell death of immortalized murine hippocampal neurons: neuroprotective activity of heme oxygenase-1, heat shock protein 70, and sodium selenite. Neurosci Lett 362(3):253–257. doi:10.1016/j.neulet.2004.03.033
11. Huang Y, Jin M, Pi R, Zhang J, Chen M, Ouyang Y, Liu A, Chao X, Liu P, Liu J, Ramassamy C, Qin J (2013) Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells. Neurosci Lett 535:146–151. doi:10.1016/j.neulet.2012.12.051
12. Mandal MN, Patlolla JM, Zheng L, Agbaga MP, Tran JT, Wicker L, Kasus-Jacobi A, Elliott MH, Rao CV, Anderson RE (2009) Curcumin protects retinal cells from light-and oxidant stress-induced cell death. Free Radic Biol Med 46(5):672–679. doi:10.1016/j.freeradbiomed.2008.12.006
13. Itoh K, Tong KI, Yamamoto M (2004) Molecular mechanism activating Nrf2–Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic Biol Med 36(10):1208–1213. doi:10.1016/j.freeradbiomed.2004.02.075
14. Gonzalez-Reyes S, Guzman-Beltran S, Medina-Campos ON, Pedraza-Chaverri J (2013) Curcumin pretreatment induces Nrf2 and an antioxidant response and prevents hemin-induced toxicity in primary cultures of cerebellar granule neurons of rats. Oxid Med Cell Longev 2013:801418. doi:10.1155/2013/801418
15. Sasaki S, Tozawa T, Sugamoto K, Matsushita Y, Satoh T (2013) A novel di terpene para-hydroquinone compound derived from cryptoquinone protects neuronal cells against oxidative stress and activates the Nrf2/ARE pathway. Neurosci Lett 548:132–136. doi:10.1016/j.neulet.2013.04.047
16. Pandey R, Mousawy K, Nagarkatti M, Nagarkatti P (2009) Endocannabinoids and immune regulation. Pharmacol Res 60(2):85–92. doi:10.1016/j.phrs.2009.03.019
17. Yoo JM, Park ES, Kim MR, Sok DE (2013) Inhibitory effect of N-Acyl dopamines on IgE-mediated allergic response in RBL-2H3 cells. Lipids 48(4):383–393. doi:10.1007/s11745-013-3758-6
18. Li H, Wood JT, Whitten KM, Vadivel SK, Seng S, Makriyannis A, Avraham HK (2013) Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells. Br J Pharmacol 170(3):489–505. doi:10.1111/bph.12111
19. Yoo JM, Sok DE, Kim MR (2013) Effect of endocannabinoids on IgE-mediated allergic response in RBL-2H3 cells. Int Immunopharmacol 17(1):123–131. doi:10.1016/j.intimp.2013.05.013
20. Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Etinger A, Mechoulam R (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258(5090):1946–1949
21. Verhoeckx KC, Voortman T, Balvers MG, Hendriks HF, Wortelboer HM, Witkamp RF (2011) Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract. Biochim Biophys Acta 1811(10):578–586. doi:10.1016/j.bbalip.2011.07.008
22. Wen LY, Bae SM, Chun HJ, Park KS, Ahn WS (2012) Therapeutic effects of systemic photodynamic therapy in a leukemia animal model using A20 cells. Lasers Med Sci 27(2):445–452. doi:10.1007/s10103-011-0950-x
23. Yang EJ, Min JS, Ku HY, Choi HS, Park MK, Kim MK, Song KS, Lee DS (2012) Isoliquiritigenin isolated from Glycyrrhiza uralensis protects neuronal cells against glutamate-induced mitochondrial dysfunction. Biochem Biophys Res Commun 421(4):658–664. doi:10.1016/j.bbrc.2012.04.053
24. Wang XJ, Sun Z, Villeneuve NF, Zhang S, Zhao F, Li Y, Chen W, Yi X, Zheng W, Wondrak GT, Wong PK, Zhang DD (2008) Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2. Carcinogenesis 29(6):1235–1243. doi:10.1093/carcin/bgn095
25. Devaney J, Curley GF, Hayes M, Masterson C, Ansari B, O’Brien T, O’Toole D, Laffey JG (2013) Inhibition of pulmonary nuclear factor kappa-B decreases the severity of acute Escherichia coli pneumonia but worsens prolonged pneumonia. Crit Care 17(2):R82. doi:10.1186/cc12696
26. Tan AA, Azman SN, Abdul Rani NR, Kua BC, Sasidharan S, Kiew LV, Othman N, Noordin R, Chen Y (2011) Optimal protein extraction methods from diverse sample types for protein profiling by using two-dimensional electrophoresis (2DE). Trop Biomed 28(3):620–629
27. Scapagnini G, Vasto S, Abraham NG, Caruso C, Zella D, Fabio G (2011) Modulation of Nrf2/ARE pathway by food polyphenols: a nutritional neuroprotective strategy for cognitive and neurodegenerative disorders. Mol Neurobiol 44(2):192–201. doi:10.1007/s12035-011-8181-5
28. Bisogno T, Melck D, Bobrov M, Gretskaya NM, Bezuglov VV, De Petrocellis L, Di Marzo V (2000) N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. Biochem J 351(Pt 3):817–824
29. Huang SM, Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, Fezza F, Tognetto M, Petros TJ, Krey JF, Chu CJ, Miller JD, Davies SN, Geppetti P, Walker JM, Di Marzo V (2002) An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci USA 99(12):8400–8405. doi:10.1073/pnas.122196999
30. Chu CJ, Huang SM, De Petrocellis L, Bisogno T, Ewing SA, Miller JD, Zipkin RE, Daddario N, Appendino G, Di Marzo V, Walker JM (2003) N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J Biol Chem 278(16):13633–13639. doi:10.1074/jbc.M211231200
31. Sancho R, Macho A, de La Vega L, Calzado MA, Fiebich BL, Appendino G, Munoz E (2004) Immunosuppressive activity of endovanilloids: N-arachidonoyl-dopamine inhibits activation of the NF-kappa B, NFAT, and activator protein 1 signaling pathways. J Immunol 172(4):2341–2351
32. Costa B, Bettoni I, Petrosino S, Comelli F, Giagnoni G, Di Marzo V (2010) The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice. Pharmacol Res 61(6):537–546. doi:10.1016/j.phrs.2010.02.001
33. Gasparotto J, de Bittencourt Pasquali MA, Somensi N, Vasques LM, Moreira JC, de Almeida RN, Barbosa-Filho JM, de Fatima Vanderlei de Souza M, Gutierrez SJ, Junior LJ, Gelain DP (2013) Effect of N-salicyloyltryptamine (STP), a novel tryptamine analogue, on parameters of cell viability, oxidative stress, and immunomodulation in RAW 264.7 macrophages. Cell Biol Toxicol 29(3):175–187. doi:10.1007/s10565-013-9245-2
34. Takahashi T, Miyazawa M (2012) N-Caffeoyl serotonin as selective COX-2 inhibitor. Bioorg Med Chem Lett 22(7):2494–2496. doi:10.1016/j.bmcl.2012.02.002
35. Nguyen CN, Kim HE, Lee SG (2013) Caffeoyl serotonin protects human keratinocyte HaCaT cells against H2 O2 -induced oxidative stress and apoptosis through upregulation of HO-1 expression via activation of the PI3K/Akt/Nrf2 pathway. Phytother Res 27(12):1810–1818. doi:10.1002/ptr.4931
36. Scapagnini G, Foresti R, Calabrese V, Giuffrida Stella AM, Green CJ, Motterlini R (2002) Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers. Mol Pharmacol 61(3):554–561
37. Joung EJ, Li MH, Lee HG, Somparn N, Jung YS, Na HK, Kim SH, Cha YN, Surh YJ (2007) Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target. Antioxid Redox Signal 9(12):2087–2098. doi:10.1089/ars.2007.1827
38. Petzer JP, Navamal M, Johnson JK, Kwak MK, Kensler TW, Fishbein JC (2003) Phase 2 enzyme induction by the major metabolite of oltipraz. Chem Res Toxicol 16(11):1463–1469. doi:10.1021/tx034154e
39. Orozco-Ibarra M, Estrada-Sanchez AM, Massieu L, Pedraza-Chaverri J (2009) Heme oxygenase-1 induction prevents neuronal damage triggered during mitochondrial inhibition: role of CO and bilirubin. Int J Biochem Cell Biol 41(6):1304–1314. doi:10.1016/j.biocel.2008.11.003
40. Xing HY, Liu Y, Chen JH, Sun FJ, Shi HQ, Xia PY (2011) Hyperoside attenuates hydrogen peroxide-induced L02 cell damage via MAPK-dependent Keap(1)–Nrf(2)–ARE signaling pathway. Biochem Biophys Res Commun 410(4):759–765. doi:10.1016/j.bbrc.2011.06.046
41. Pan LL, Liu XH, Jia YL, Wu D, Xiong QH, Gong QH, Wang Y, Zhu YZ (2013) A novel compound derived from danshensu inhibits apoptosis via upregulation of heme oxygenase-1 expression in SH-SY5Y cells. Biochim Biophys Acta 1830(4):2861–2871. doi:10.1016/j.bbagen.2013.01.008
42. Yan J, Roy S, Apolloni A, Lane A, Hancock JF (1998) Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase. J Biol Chem 273(37):24052–24056
43. Shankar S, Chen Q, Srivastava RK (2008) Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor. J Mol Signal 3:7. doi:10.1186/1750-2187-3-7