Metabolic engineering of Escherichia coli for efficient production of (3R)-acetoin

Journal of Chemical Technology and Biotechnology

Volumn 90, Issue 1, 2015, Pages 93-100

  Xu, Quanming ^a   Xie, Linxiang ^a   Li, Yongyu ^a   Lin, Hui ^a   Sun, Shujing ^a   Guan, Xiong ^a   Hu, Kaihui ^a   Shen, Yaling ^b   Zhang, Liaoyuan ^a  

^a FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

(3R) acetoin; Escherichia coli; Fed batch; Medium optimization; Metabolic engineering

Indexed keywords

BATCH CELL CULTURE; BOTTLES; ESCHERICHIA COLI; FERMENTATION; GENES; KETONES; LIQUID CRYSTALS; METABOLISM;

ACETOIN; CULTURE MEDIUM OPTIMIZATION; FED BATCHES; LIQUID-CRYSTAL COMPOSITES; MEDIUM OPTIMIZATION; ORTHOGONAL DESIGN METHOD; PHARMACEUTICAL INTERMEDIATES; RECOMBINANT ESCHERICHIA COLI;

METABOLIC ENGINEERING;

2,3 BUTANEDIOL; ACETOIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ACIDIFICATION; AERATION; ARTICLE; BACTERIAL GENE; BATCH FERMENTATION; BIOSYNTHESIS; CELL GROWTH; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; EXPERIMENTAL DESIGN; FED BATCH CULTURE; FED BATCH FERMENTATION; GAS CHROMATOGRAPHY; GENE EXPRESSION; LACTOBACILLUS BREVIS; METABOLIC ENGINEERING; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PROCESS CONTROL; SERRATIA MARCESCENS; STEREOISOMERISM; TEMPERATURE;

ESCHERICHIA COLI;

EID: 84912528330     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.4293     Document Type: Article

References (30)

1. Zhang LY, Chen S, Xie HB, Tian YT and Hu KH, Efficient acetoin production by optimization of medium components and oxygen supply control using a newly isolated Paenibacillus polymyxa CS107. J Chem Technol Biotechnol 87:1551-1557 (2012).
2. Sun JA, Zhang LY, Rao B, Han YB, Chu J, Zhu JW, Shen YL and Wei DZ, Enhanced acetoin production by Serratia marcescens H32 using statistical optimization and two-stage agitation speed control strategy. Biotechnol Bioproc E 17:598-605 (2012).
3. Xiao ZJ, Liu PH, Qin JY and Xu P, Statistical optimization of medium components for enhanced acetoin production from molasses and soybean meal hydrolysate. Appl Microbiol Biotechnol 74:61-68 (2007).
4. Xiao ZJ, Qiao SL, Ma CQ and Xu P, Acetoin production associated with the increase of cell biomass in Bacillus pumilus ATCC 14884. Afr J Microbiol Res 4:1997-2003 (2010).
5. Zhang X, Yang TW, Lin Q, Xu MJ, Xia HF, Xu ZH, Li HZ and Rao ZM, Isolation and identification of an acetoin high production bacterium that can reverse transform 2, 3-butanediol to acetoin at the decline phase of fermentation. World J Microbiol Biotechnol 27:2785-2790 (2011).
6. Xiao ZJ, Lv CJ, Gao C, Qin JY, Ma CQ, Liu Z, Liu PH, Li LX and Xu P, A novel whole-cell biocatalyst with NAD+regeneration for production of chiral chemicals. Plos One 5:e8860 (2010).
7. Ji XJ, Huang H and Ouyang PK, Microbial 2, 3-butanediol production: a state-of-the-art review. Biotechnol Adv 29:351-364 (2011).
8. Häßler T, Schieder D, Pfaller R, Faulstich M and Sieber V, Enhanced fed-batch fermentation of 2, 3-butanediol by Paenibacillus polymyxa DSM 365. Bioresource Technol 124:237-244 (2012).
9. Xu H, Jia SR and Liu JJ, Development of a mutant strain of Bacillus subtilis showing enhanced production of acetoin. Afr J Biotechnol 10:779-788 (2011).
10. Liu YF, Zhang SL, Yong YC, Ji ZX, Ma X, Xu ZH and Chen SW, Efficient production of acetoin by the newly isolated Bacillus licheniformis strain MEL09. Process Biochem 46:390-394 (2011).
11. Wang M, Fu J, Zhang XY and Chen T, Metabolic engineering of Bacillus subtilis for enhanced production of acetoin. Biotechnol Lett 34:1877-1885 (2012).
12. Zhang LY, Xu QM, Zhan SR, Li YY, Lin H, Sun SJ, Sha L, Hu KH, Guan X and Shen YL, A new NAD(H)-dependent meso-2, 3-butanediol dehydrogenase from an industrially potential strain Serratia marcescens H30. Appl Microbiol Biotechnol DOI 10.1007/s00253-013-4959-x (2013). Latest info required
13. Sun JA, Zhang LY, Rao B, Shen YL and Wei DZ, Enhanced acetoin production by Serratia marcescens H32 with expression of a water-forming NADH oxidase. Bioresource Technol 119:94-98 (2012).
14. Celinska E and Grajek W, Biotechnological production of 2, 3-butanediol-current state and prospects. Biotechnol Adv 27:715-725 (2009).
15. Zhang GL, Wang CW and Li C, Cloning, expression and characterization of meso-2, 3-butanediol dehydrogenase from Klebsiella pneumoniae. Biotechnol Lett 34:1519-1523 (2012).
16. Liu Z, Qin JY, Gao C, Hua DL, Ma CQ, Li LX, Wang Y and Xu P, Production of (2S, 3S)-butanediol and (3S)-acetoin from glucose using resting cells of Klebsiella pneumonia and Bacillus subtilis. Bioresource Technol 102:10741-10744 (2011).
17. Xiao ZJ and Xu P, Acetoin metabolism in bacteria. Crit Rev Microbiol 33:127-140 (2007).
18. Cho S, Kim KD, Ahn JH, Lee J, Kim SW and Um Y, Selective production of 2, 3-butanediol and acetoin by a newly isolated bacterium Klebsiella oxytoca M1. Appl Biochem Biotechnol 8:1922-1933 (2013).
19. Gao C, Zhang LJ, Xie YJ, Hu CH, Zhang Y, Li LX, Wang Y, Ma CQ and Xu P, Production of (3S)-acetoin from diacetyl by using stereoselective NADPH-dependent carbonyl reductase and glucose dehydrogenase. Bioresource Technol 137:111-115 (2013).
20. Ui S, Mimura A, Okuma M and Kudo T, The production of D-acetoin by a transgenic Escherichia coli. Lett Appl Microbiol 26:275-278 (1998).
21. Rao B, Zhang LY, Sun JA, Su G, Wei DZ, Chu J, Zhu JW and Shen YL, Characterization and regulation of the 2, 3-butanediol pathway in Serratia marcescens. Appl Microbiol Biotechnol 93:2147-2159 (2012).
22. Zhang LY, Xu QM, Sun JA, Wei DZ and Shen YL, Identification of the regulatory gene controlling the acetoin fermentation pathway in Serratia marcescens H30. Acta Agriculture Universitatis Jiangxiensis 34:706-711 (2012).
23. Geueke B, Riebel B and Hummel W, NADH oxidase from NADH oxidase from Lactobacillus brevis: a new catalyst for the regeneration of NAD. Enzyme Microbiol Technol 32:205-211 (2003).
24. Yokota A, Henmi M, Takaoka N and Hayashi C, Enhancement of glucose metabolism in a pyruvic acid-hyperproducing Escherichia coli mutant defective in F1-ATPase activity. J Ferment Bioeng 83:132-138 (1997).
25. Zhang YJ, Li SB, Liu LM and Wu J, Acetoin production enhanced by manipulating carbon flux in a newly isolated Bacillus amyloliquefaciens. Bioresource Technol 130:256-260 (2013).
26. Ui S, Okajima Y, Mimura A, Kanai H and Kudo T, Molecular generation of an Escherichia coli strain producing only the meso-isomer of 2, 3-butanediol. J Ferment Bioeng 84:185-189 (1997).
27. Kovacikova G, Lin W and Skorupski K, Dual regulation of genes involved in acetoin biosynthesis and motility/biofilm formation by the virulence activator AphA and the acetate-responsive LysR-type regulator AlsR in Vibrio cholerae. Mol Microbiol 57:420-433 (2005).
28. Ji XJ, Xia ZF, Fu NH, Nie ZK, Shen MQ, Tian QQ and Huang H, Cofactor engineering through heterologous expression of an NADH oxidase and its impact on metabolic flux redistribution in Klebsiella pneumoniae. Biotechnol Biofuels 6:7 (2013).
29. Zhang LY, Yang YL, Sun JA, Shen YL, Wei DZ, Zhu JW and Chu J, Microbial production of 2, 3-butanediol by a mutagenized strain of Serratia marcescens H30. Bioresource Technol 101:1961-1967 (2010).
30. Zeng AP, Byun TG, Posten C and Deckwer WD, Use of respiratory quotient as a control parameter for optimum oxygen supply and scale-up of 2, 3-butanediol production under microaerobic conditions. Biotechnol Bioeng 44:1107-1114 (1994).