Characterization and regulation of the 2,3-butanediol pathway in Serratia marcescens

Applied Microbiology and Biotechnology

Volumn 93, Issue 5, 2012, Pages 2147-2159

  Rao, Ben ^a   Zhang, Liao Yuan ^b   Sun, Jian'an ^a   Su, Gang ^a   Wei, Dongzhi ^a   Chu, Ju ^a   Zhu, Jiawen ^c   Shen, Yaling ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

^c EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

2,3 Butanediol; Acetoin; Regulation; Serratia marcescens

Indexed keywords

2 ,3-BUTANEDIOL; ACETOIN; ACETOLACTATE SYNTHASE; DECARBOXYLASES; HIGH YIELD; INDUSTRIAL PRODUCTION; KLEBSIELLA; KLEBSIELLA SP; POTENTIAL STRAIN; REGULATION; SERRATIA MARCESCENS; STRAIN IMPROVEMENT; VIBRIO CHOLERAE; VIBRIO SP;

CLONING; GENES;

TRANSCRIPTION;

2,3 BUTANEDIOL; 2,3 BUTANEDIOL DEHYDROGENASE; ACETOIN; ACETOLACTATE DECARBOXYLASE; ACETOLACTATE SYNTHASE; CARBOXYLYASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

BACTERIUM; ENZYME ACTIVITY; EXPERIMENTAL STUDY; FERMENTATION; GENE EXPRESSION;

ARTICLE; BATCH FERMENTATION; CONTROLLED STUDY; GENE; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; KLEBSIELLA; KLEBSIELLA PNEUMONIAE; MOLECULAR CLONING; QUORUM SENSING; REGULATOR GENE; SERRATIA MARCESCENS; SLAR GENE; SLAR REGULATOR GENE; SWRI GENE; SWRR REGULATOR GENE; VIBRIO; VIBRIO CHOLERAE;

ACETOLACTATE SYNTHASE; ALCOHOL OXIDOREDUCTASES; BACTERIAL PROTEINS; BUTYLENE GLYCOLS; CARBOXY-LYASES; CLONING, MOLECULAR; DNA, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; METABOLIC NETWORKS AND PATHWAYS; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA; SERRATIA MARCESCENS; TRANSCRIPTION FACTORS;

KLEBSIELLA; KLEBSIELLA SP.; SERRATIA MARCESCENS; VIBRIO CHOLERAE; VIBRIO SP.;

EID: 84857915171     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3608-5     Document Type: Article

References (26)

1. Blomqvist K, Nikkola M, Lehtovaara P, Suihko ML, Airaksinen U, Stråby KB, Knowles JK, Penttilä ME (1993) Characterization of the genes of the 2,3-butanediol operons from Klebsiella terrigena and Enterobacter aerogenes. J Bacteriol 175:1392-1404 (Pubitemid 23081816)
2. Celinska E, Grajek W (2009) Biotechnological production of 2,3-butanediol current state and prospects. Biotechnol Adv 27:715-725
3. Eberl L, Winson MK, Sternberg C, Stewart GSAB, Christiansen G, Chhabra SR, Bycroft B, Williams P, Molin S, Givskov M (1996) Involvement of N-acyl-L-homoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens. Mol Microbiol 20:127-136
4. Henikoff S, Haughn G, Calvo J, Wallace J (1988) A large family of bacterial activator proteins. Proc Natl Acad Sci USA 85:6602-6606
5. Hoang TT, Karkhoff-Schweizer RR, Kutchma AJ, Schweizer HP (1998) A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 212:77-86 (Pubitemid 28269135)
6. Holtzclaw WD, Chapman LF (1975) Degradative acetolactate synthase of Bacillus subtilis: purification and properties. J Bacteriol 121:917-922
7. Horng YT, Deng SC, Daykin M, Soo PC, Wei JR, Luh KT, Ho SW, Swift S, Lai HC, Williams P (2002) The LuxR family protein SpnR functions as a negative regulator of N-acylhomoserine lactone-dependent quorum sensing in Serratia marcescens. Mol Microbiol 45:1655-1671 (Pubitemid 35231981)
8. Ji XJ, Huang H, Ouyang PK (2011) Microbial 2,3-butanediol production: a state-of-the-art review. Biotechnol Adv 29:351-364
9. Joo HS, Kim SS (1998) Purification and characterization of the catabolic alpha-acetolactate synthase from Serratia marcescens. J Biochem Mol Biol 31:37-43 (Pubitemid 128539611)
10. Joseph S, David WR (2001) Molecular cloning: a laboratory manual, Third editionth edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
11. Kovacikova G, Lin W, Skorupskim K (2005) Dual regulation of genes involved in acetoin biosynthesis and motility/biofilm formation by the virulence activator AphA and the acetate-responsive LysR-type regulator AlsR in Vibrio cholerae. Mol Microbiol 57:420-433 (Pubitemid 40979343)
12. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-delta delta C (T)) method. Methods 25:402-408 (Pubitemid 34164012)
13. Loken JP, Stormer FC (1970) Acetolactate decarboxylase from Aerobacter aerogenes: purification and properties. Eur J Biochem 14:133-137
14. Moons P, Van Houdt R, Vivijs B, Michiels CW, Aertsen A (2011) Integrated regulation of acetoin fermentation by quorum sensing and pH in Serratia plymuthica RVH1. Appl Environ Microb 77:3422-3427
15. Nicholson WL (2008) The Bacillus subtilis ydjL(bdhA) gene encodes acetoin reductase/2,3-butanediol dehydrogenase. Appl Environ Microb 74:6832-6838
16. Ovadis M, Liu X, Gavriel S, Ismailov Z, Chet I, Chernin L (2004) The global regulator genes from biocontrol strain Serratia plymuthica IC1270: cloning, sequencing, and functional studies. J Bacteriol 186:4986-4993 (Pubitemid 38970826)
17. Renna MC, Najimudin J, Winik LR, Zahler SA (1993) Regulation of the Bacillus subtilis alsS, alsD, and alsR genes involved in post-exponential-phase production of acetoin. J Bacteriol 175:3863-3875 (Pubitemid 23173348)
18. Rice SA, Koh KS, Queck SY, Labbate M, Lam KW, Kjelleberg S (2005) Biofilm formation and sloughing in Serratia marcescens are controlled by quorum sensing and nutrient cues. J Bacteriol 187:3477-3485 (Pubitemid 40628704)
19. Riedel K, Ohnesorg T, Krogfelt K, Hansen TS, Omori K, Givskov M, Eberl L (2001) N-acyl-L-homoserine lactone-mediated regulation of the lip secretion system in Serratia liquefaciens MG1. J Bacteriol 183:1805-1809 (Pubitemid 32172329)
20. Rostgaard Jensen B, Svendsen I, Ottesen M (1987) Isolation and characterization of an alpha-acetolactate decarboxylase useful for accelerated beer maturation. Proc Congr Eur Brew Conv 21:393-400
21. Schell M (1993) Molecular biology of the LysR family of transcriptional regulators. Annu Rev Microbiol 47:597-626
22. Syu MJ (2001) Biological production of 2,3-butanediol. Appl Microbiol Biotechnol 55:10-18
23. Van Houdt R, Moons P, Hueso Buj M, Michiels CW (2006) N-acyl-Lhomoserine lactone quorum sensing controls butanediol fermentation in Serratia plymuthica RVH1 and Serratia marcescens MG1. J Bacteriol 188:4570-4572 (Pubitemid 43865776)
24. Van Houdt R, Aertsen A, Michiels CW (2007) Quorum-sensingdependent switch to butanediol fermentation prevents lethal medium acidification in Aeromonas hydrophila AH-1 N. Res Microbiol 158:379-385 (Pubitemid 46810202)
25. Xiu ZL, Zeng AP (2008) Present state and perspective of downstream processing of biologically produced 1,3-propanediol and 2,3-butanediol. Appl Microbiol Biotechnol 78:917-926
26. Zhang LY, Yang YL, Sun JA, Shen YL, Wei DZ, Zhu JW, Chu J (2010) Microbial production of 2,3-butanediol by a mutagenized strain of Serratia marcescens H30. Bioresour Technol 101:1961-1967