-
1
-
-
0031152162
-
Structural analysis of nucleic acid aptamers
-
Patel D.J. Structural analysis of nucleic acid aptamers. Curr Opin Chem Biol 1997, 1:32-46.
-
(1997)
Curr Opin Chem Biol
, vol.1
, pp. 32-46
-
-
Patel, D.J.1
-
2
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk C., Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 1990, 249:505-510.
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
3
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington A.D., Szostak J.W. In vitro selection of RNA molecules that bind specific ligands. Nature 1990, 346:818-822.
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
4
-
-
0034603154
-
Adaptive recognition by nucleic acid aptamers
-
Hermann T., Patel D.J. Adaptive recognition by nucleic acid aptamers. Science 2000, 287:820-825.
-
(2000)
Science
, vol.287
, pp. 820-825
-
-
Hermann, T.1
Patel, D.J.2
-
6
-
-
33645095226
-
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
-
Ng E.W.M., Shima D.T., Calias P., Cunningham E.T., Guyer D.R., Adamis A.P. Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nature Rev Drug Dis 2006, 5:123-132.
-
(2006)
Nature Rev Drug Dis
, vol.5
, pp. 123-132
-
-
Ng, E.W.M.1
Shima, D.T.2
Calias, P.3
Cunningham, E.T.4
Guyer, D.R.5
Adamis, A.P.6
-
7
-
-
0032860385
-
Aptamers: an emerging class of molecules that rival antibodies in diagnostics
-
Jayasena S.D. Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clin Chem 1999, 9:1628-1650.
-
(1999)
Clin Chem
, vol.9
, pp. 1628-1650
-
-
Jayasena, S.D.1
-
8
-
-
84875287450
-
A review of therapeutic aptamer conjugates with emphasis on new approaches
-
Bruno J.G. A review of therapeutic aptamer conjugates with emphasis on new approaches. Pharmaceuticals 2013, 6:340-357.
-
(2013)
Pharmaceuticals
, vol.6
, pp. 340-357
-
-
Bruno, J.G.1
-
9
-
-
84899760519
-
Aptamer-modified nanoparticles and their use in cancer diagnostics and treatment
-
Reinemann C., Strehlitz B. Aptamer-modified nanoparticles and their use in cancer diagnostics and treatment. Swiss Med Wkly 2014, 144:w13908.
-
(2014)
Swiss Med Wkly
, vol.144
, pp. w13908
-
-
Reinemann, C.1
Strehlitz, B.2
-
12
-
-
84856389509
-
RNA-based therapeutics: current progress and future prospects
-
Burnett J.C., Rossi J.J. RNA-based therapeutics: current progress and future prospects. Chem Biol 2012, 19:60-71.
-
(2012)
Chem Biol
, vol.19
, pp. 60-71
-
-
Burnett, J.C.1
Rossi, J.J.2
-
13
-
-
84870680921
-
Therapeutic RNA aptamers in clinical trials
-
Sundaram P., Kurniawan H., Byrne M.E., Wower J. Therapeutic RNA aptamers in clinical trials. Eur J Pharm Sci 2013, 48:259-271.
-
(2013)
Eur J Pharm Sci
, vol.48
, pp. 259-271
-
-
Sundaram, P.1
Kurniawan, H.2
Byrne, M.E.3
Wower, J.4
-
14
-
-
44149123383
-
Structural and molecular basis for hyperspecificity of RNA aptamer to human IgG
-
Miyakawa S., Nomura Y., Sakamoto T., Yamaguchi Y., Kato K., Yamazaki S., et al. Structural and molecular basis for hyperspecificity of RNA aptamer to human IgG. RNA 2008, 14:1154-1163.
-
(2008)
RNA
, vol.14
, pp. 1154-1163
-
-
Miyakawa, S.1
Nomura, Y.2
Sakamoto, T.3
Yamaguchi, Y.4
Kato, K.5
Yamazaki, S.6
-
15
-
-
78649830305
-
Conformational plasticity of RNA for target recognition as revealed by the 2.15Å crystal structure of a human IgG-aptamer complex
-
Nomura Y., Sugiyama S., Sakamoto T., Miyakawa S., Adachi H., Takano K., et al. Conformational plasticity of RNA for target recognition as revealed by the 2.15Å crystal structure of a human IgG-aptamer complex. Nucleic Acid Res 2010, 38:7822-7829.
-
(2010)
Nucleic Acid Res
, vol.38
, pp. 7822-7829
-
-
Nomura, Y.1
Sugiyama, S.2
Sakamoto, T.3
Miyakawa, S.4
Adachi, H.5
Takano, K.6
-
16
-
-
1142286441
-
Interactions of immunoglobulins outside the antigen-combining site
-
Nezlin R., GheŤie V. Interactions of immunoglobulins outside the antigen-combining site. Adv Immunol 2004, 82:155-215.
-
(2004)
Adv Immunol
, vol.82
, pp. 155-215
-
-
Nezlin, R.1
GheŤie, V.2
-
17
-
-
70349783997
-
RNA aptamers specifically interact with the Fc region of mouse IgG
-
Sakai N., Masuda H., Akitomi J., Yagi H., Yoshida Y., Horii K., et al. RNA aptamers specifically interact with the Fc region of mouse IgG. Nucleic Acid Symp Ser (Oxf) 2008, 52:487-488.
-
(2008)
Nucleic Acid Symp Ser (Oxf)
, vol.52
, pp. 487-488
-
-
Sakai, N.1
Masuda, H.2
Akitomi, J.3
Yagi, H.4
Yoshida, Y.5
Horii, K.6
-
18
-
-
84876831541
-
Target replacement strategy for selection of DNA aptamers against the Fc region of mouse IgG
-
Ma J., Wang M.G., Mao A.H., Zeng J.Y., Liu Y.Q., Wang X.Q., et al. Target replacement strategy for selection of DNA aptamers against the Fc region of mouse IgG. Genet Mol Res 2013, 12:1399-1410.
-
(2013)
Genet Mol Res
, vol.12
, pp. 1399-1410
-
-
Ma, J.1
Wang, M.G.2
Mao, A.H.3
Zeng, J.Y.4
Liu, Y.Q.5
Wang, X.Q.6
-
19
-
-
40649092265
-
Rabbit antibody detection with DNA aptamers
-
Yoshida Y., Sakai N., Masuda H., Furuichi M., Nishikawa F., Nishikawa S., et al. Rabbit antibody detection with DNA aptamers. Anal Biochem 2008, 375:217-222.
-
(2008)
Anal Biochem
, vol.375
, pp. 217-222
-
-
Yoshida, Y.1
Sakai, N.2
Masuda, H.3
Furuichi, M.4
Nishikawa, F.5
Nishikawa, S.6
-
20
-
-
16244416540
-
DNA aptamer-based bioanalysis of IgE by fluorescence anisotropy
-
Gokulrangan G., Unruh J.R., Holub D.F., Ingram B., Johnson C.K., Wilson G.S. DNA aptamer-based bioanalysis of IgE by fluorescence anisotropy. Anal Chem 2005, 77:1963-1970.
-
(2005)
Anal Chem
, vol.77
, pp. 1963-1970
-
-
Gokulrangan, G.1
Unruh, J.R.2
Holub, D.F.3
Ingram, B.4
Johnson, C.K.5
Wilson, G.S.6
-
21
-
-
84880161343
-
CD28 aptamers as powerful immune response modulators
-
Pastor F., Soldevilla M.M., Villanueva H., Kolonias D., Inoges S., de Cerio A.L., et al. CD28 aptamers as powerful immune response modulators. Mol Ther Nuleic Acids 2013, 2:e98.
-
(2013)
Mol Ther Nuleic Acids
, vol.2
, pp. e98
-
-
Pastor, F.1
Soldevilla, M.M.2
Villanueva, H.3
Kolonias, D.4
Inoges, S.5
de Cerio, A.L.6
-
22
-
-
0242610799
-
Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity
-
Santulli-Marotto S., Nair S.K., Rusconi C., Sullinger B., Gilboa E. Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity. Cancer Res 2003, 63:7483-7489.
-
(2003)
Cancer Res
, vol.63
, pp. 7483-7489
-
-
Santulli-Marotto, S.1
Nair, S.K.2
Rusconi, C.3
Sullinger, B.4
Gilboa, E.5
-
24
-
-
84874912010
-
Use of oligonucleotide aptamer ligands to modulate the function of immune receptors
-
Gilboa E., McNamara J., Pastor F. Use of oligonucleotide aptamer ligands to modulate the function of immune receptors. Clin Cancer Res 2013, 19:1054-1062.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1054-1062
-
-
Gilboa, E.1
McNamara, J.2
Pastor, F.3
-
25
-
-
46849111987
-
Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer
-
Dollins C.M., Nair S., Boczkowski D., Lee J., Layzer J.M., Gilboa E., et al. Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer. Chem Biol 2008, 15:675-682.
-
(2008)
Chem Biol
, vol.15
, pp. 675-682
-
-
Dollins, C.M.1
Nair, S.2
Boczkowski, D.3
Lee, J.4
Layzer, J.M.5
Gilboa, E.6
-
26
-
-
84861902826
-
Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing
-
Berezhnoy A., Stewart C.A., McNamara J.O., Thiel W., Giangrande P., Trinchiery G., et al. Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing. Mol Ther 2012, 20:1242-1250.
-
(2012)
Mol Ther
, vol.20
, pp. 1242-1250
-
-
Berezhnoy, A.1
Stewart, C.A.2
McNamara, J.O.3
Thiel, W.4
Giangrande, P.5
Trinchiery, G.6
-
27
-
-
84892941233
-
Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity
-
Berezhnoy A., Castro I., Levay A., Malek T.R., Gilboa E. Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity. J Clin Invest 2014, 24:188-197.
-
(2014)
J Clin Invest
, vol.24
, pp. 188-197
-
-
Berezhnoy, A.1
Castro, I.2
Levay, A.3
Malek, T.R.4
Gilboa, E.5
-
28
-
-
80053576818
-
Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers
-
Pastor F., Kolonias D., McNamara J.O., Gilboa E. Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers. Mol Ther 2011, 19:1878-1886.
-
(2011)
Mol Ther
, vol.19
, pp. 1878-1886
-
-
Pastor, F.1
Kolonias, D.2
McNamara, J.O.3
Gilboa, E.4
-
29
-
-
77952380547
-
Induction of tumor immunity by targeted inhibition of nonsense-mediated mRNA decay
-
Pastor F., Kolonias D., Giangrande P., Gilboa E. Induction of tumor immunity by targeted inhibition of nonsense-mediated mRNA decay. Nature 2010, 465:27-31.
-
(2010)
Nature
, vol.465
, pp. 27-31
-
-
Pastor, F.1
Kolonias, D.2
Giangrande, P.3
Gilboa, E.4
-
30
-
-
84891488177
-
Expression of new antigens on tumor cells by inhibiting nonsense-mediated mRNA decay
-
Gilboa E. Expression of new antigens on tumor cells by inhibiting nonsense-mediated mRNA decay. Immunol Res 2013, 57:44-51.
-
(2013)
Immunol Res
, vol.57
, pp. 44-51
-
-
Gilboa, E.1
-
31
-
-
79953706298
-
A multivalent DNA aptamer specific to the B-cell receptor on human lymphoma and leukemia
-
Mallikaratchy P.R., Ruggiero A., Gardner J.R., Kuryavyi V., Maguire W.F., Heaney M.L., et al. A multivalent DNA aptamer specific to the B-cell receptor on human lymphoma and leukemia. Nucleic Acids Res 2011, 39:2458-2469.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 2458-2469
-
-
Mallikaratchy, P.R.1
Ruggiero, A.2
Gardner, J.R.3
Kuryavyi, V.4
Maguire, W.F.5
Heaney, M.L.6
-
32
-
-
37849002321
-
Toll-like receptor 9 (TLR9) agonist in the treatment of cancer
-
Krieg A.M. Toll-like receptor 9 (TLR9) agonist in the treatment of cancer. Oncogene 2008, 27:161-167.
-
(2008)
Oncogene
, vol.27
, pp. 161-167
-
-
Krieg, A.M.1
-
33
-
-
84859489110
-
CpG rocks! Update on an accidental drug
-
Krieg A.M. CpG rocks! Update on an accidental drug. Nucleic Acids Ther 2012, 22:77-89.
-
(2012)
Nucleic Acids Ther
, vol.22
, pp. 77-89
-
-
Krieg, A.M.1
-
34
-
-
0033062077
-
Derivation of RNA aptamer inhibitors of human complement C5
-
Biesecker G., Dihel L., Enney K., Bendele R.A. Derivation of RNA aptamer inhibitors of human complement C5. Immunopharmacology 1999, 42:219-230.
-
(1999)
Immunopharmacology
, vol.42
, pp. 219-230
-
-
Biesecker, G.1
Dihel, L.2
Enney, K.3
Bendele, R.A.4
-
35
-
-
84890118282
-
A novel c5a-neutralizing mirror-image (l-) aptamer prevents organ failure and improves survival in experimental sepsis
-
Hoehlig K., Maasch C., Shushakova N., Buchner K., Huber-Lang M., et al. A novel c5a-neutralizing mirror-image (l-) aptamer prevents organ failure and improves survival in experimental sepsis. Mol Ther 2013, 21:2236-2246.
-
(2013)
Mol Ther
, vol.21
, pp. 2236-2246
-
-
Hoehlig, K.1
Maasch, C.2
Shushakova, N.3
Buchner, K.4
Huber-Lang, M.5
-
36
-
-
80052435113
-
Dual blockade of the homeostatic chemokine CXCL12 and the proinflammatory chemokine CCL2 has additive protective effects on diabetic kidney
-
Darisipudi M.N., Kulkarni O.P., Sayyed S.G., Ryu M., Migliorini A., Sagrinati C., et al. Dual blockade of the homeostatic chemokine CXCL12 and the proinflammatory chemokine CCL2 has additive protective effects on diabetic kidney. Am J Pathol 2011, 21:116-124.
-
(2011)
Am J Pathol
, vol.21
, pp. 116-124
-
-
Darisipudi, M.N.1
Kulkarni, O.P.2
Sayyed, S.G.3
Ryu, M.4
Migliorini, A.5
Sagrinati, C.6
-
37
-
-
84871462966
-
Quantitative and sensitive protein detection strategies based on aptamers
-
Yoshida Y., Waga I., Horii K. Quantitative and sensitive protein detection strategies based on aptamers. Proteom Clin Appl 2012, 6:574-580.
-
(2012)
Proteom Clin Appl
, vol.6
, pp. 574-580
-
-
Yoshida, Y.1
Waga, I.2
Horii, K.3
-
38
-
-
78650149915
-
Aptamer-based multiplexed proteomic technology for biomarker discovery
-
Gold L., Ayers D., Bertino J., Bock C., Bock A., Brody E.N., et al. Aptamer-based multiplexed proteomic technology for biomarker discovery. PloS ONE 2010, 5:e15004.
-
(2010)
PloS ONE
, vol.5
, pp. e15004
-
-
Gold, L.1
Ayers, D.2
Bertino, J.3
Bock, C.4
Bock, A.5
Brody, E.N.6
-
39
-
-
10044277172
-
Aptasensor development: elucidation of critical parameters for optimal aptamer performance
-
Baldrich E., Restrepo A., O'Sullivan C.K. Aptasensor development: elucidation of critical parameters for optimal aptamer performance. Anal Chem 2004, 76:7053-7063.
-
(2004)
Anal Chem
, vol.76
, pp. 7053-7063
-
-
Baldrich, E.1
Restrepo, A.2
O'Sullivan, C.K.3
-
40
-
-
84883474171
-
Dual-aptamer-based biosensing of toxoplasma antibody
-
Luo Y., Liu X., Jiang T., Liao P., Fu W. Dual-aptamer-based biosensing of toxoplasma antibody. Anal Chem 2013, 85:8354-8360.
-
(2013)
Anal Chem
, vol.85
, pp. 8354-8360
-
-
Luo, Y.1
Liu, X.2
Jiang, T.3
Liao, P.4
Fu, W.5
-
41
-
-
84877854501
-
Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth
-
Mahlknecht G., Maron R., Mancini M., Schechter B., Sela M., Yarden Y. Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth. Proc Natl Acad Sci U S A 2013, 110:8170-8175.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 8170-8175
-
-
Mahlknecht, G.1
Maron, R.2
Mancini, M.3
Schechter, B.4
Sela, M.5
Yarden, Y.6
-
42
-
-
84906856046
-
Aptamers as drug delivery vehicles
-
Kruspe S., Mittelberger F., Szameit K., Hahn U. Aptamers as drug delivery vehicles. ChemMedChem 2014, 9:1998-2011.
-
(2014)
ChemMedChem
, vol.9
, pp. 1998-2011
-
-
Kruspe, S.1
Mittelberger, F.2
Szameit, K.3
Hahn, U.4
-
43
-
-
84902825431
-
Cell-type-specific, aptamer-functionalized agents for targeted disease therapy
-
Zhou J., Rossi J.J. Cell-type-specific, aptamer-functionalized agents for targeted disease therapy. Mol Ther Nucleic Acid 2014, 3:e169.
-
(2014)
Mol Ther Nucleic Acid
, vol.3
, pp. e169
-
-
Zhou, J.1
Rossi, J.J.2
|