Trehalose, an mTOR independent autophagy inducer, alleviates human podocyte injury after puromycin aminonucleoside treatment

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Kang, Yu Lin ^a,b   Saleem, Moin Ahson ^c   Chan, Kwok Wah ^d   Yung, Benjamin Yat Ming ^a   Law, Helen Ka Wai ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PUROMYCIN AMINONUCLEOSIDE; REACTIVE OXYGEN METABOLITE; TREHALOSE; ANTINEOPLASTIC ANTIBIOTIC; ATG5 PROTEIN, HUMAN; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ACTIN FILAMENT; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DAMAGE; CELL DEATH; CELL MIGRATION; CELL MOTILITY; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; IN VITRO STUDY; PODOCYTE; SIGNAL TRANSDUCTION; CELL LINE; CELL MOTION; CYTOLOGY; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; IMMUNOLOGY; LIPOID NEPHROSIS; METABOLISM; PATHOLOGY; WESTERN BLOTTING;

ACTIN CYTOSKELETON; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE; CELL MOVEMENT; HUMANS; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; NEPHROSIS, LIPOID; PODOCYTES; PUROMYCIN AMINONUCLEOSIDE; REACTIVE OXYGEN SPECIES; TOR SERINE-THREONINE KINASES; TREHALOSE;

EID: 84912050143     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113520     Document Type: Article

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