Phenolic metabolites of benzene induced caspase-dependent cytotoxicities to K562 cells accompanied with decrease in cell surface sialic acids

Environmental Toxicology

Volumn 29, Issue 12, 2014, Pages 1437-1451

  Wang, Yan ^a   Zhang, Guang Yao ^a   Han, Qing Ling ^a   Wang, Jie ^a   Li, Yang ^a   Yu, Chun Hong ^a   Li, Yi Ran ^a   Yi, Zong Chun ^a  

^a BEIHANG UNIVERSITY   (China)

Author keywords

Apoptosis; Benzene metabolites; Caspases; Reactive oxygen species; Sialic acid

Indexed keywords

ACETYLCYSTEINE; AMINO ACIDS; BENZENE; BIOMOLECULES; CARBOXYLIC ACIDS; CELL DEATH; CELL MEMBRANES; CYTOTOXICITY; GENES; PHENOLS;

APOPTOTIC PROCESS; CASPASES; N-ACETYL L-CYSTEINE; PHENOLIC METABOLITES; PHOSPHATIDYLSERINE; REACTIVE OXYGEN SPECIES; SIALIC ACIDS; SIALIDASE ACTIVITIES;

METABOLITES;

1,2,4 BENZENETRIOL; ACETYLCYSTEINE; BENZENE; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CATECHOL; FAS ANTIGEN; FAS LIGAND; HYDROQUINONE; MESSENGER RNA; PHENOL DERIVATIVE; REACTIVE OXYGEN METABOLITE; SIALIC ACID DERIVATIVE; SIALIDASE; BENZENE DERIVATIVE; CATECHOL DERIVATIVE; HYDROQUINONE DERIVATIVE; PHENOL;

APOPTOSIS; ARTICLE; CELL AGGREGATION; CELL LEVEL; CELL SURFACE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; GENE; GENE EXPRESSION; K-562 CELL LINE; METABOLITE; NEU3 GENE; ST3GAL3 GENE; CELL MEMBRANE; HUMAN; K562 CELL LINE; METABOLISM;

APOPTOSIS; BENZENE DERIVATIVES; CASPASES; CATECHOLS; CELL MEMBRANE; HUMANS; HYDROQUINONES; K562 CELLS; PHENOL; REACTIVE OXYGEN SPECIES; SIALIC ACIDS;

EID: 84911959742     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21874     Document Type: Article

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