Catechol cytotoxicity in vitro: Induction of glioblastoma cell death by apoptosis

Human and Experimental Toxicology

Volumn 29, Issue 3, 2010, Pages 199-212

  De Oliveira, D M ^a   Pitanga, B P S ^a   Grangeiro, M S ^a   Lima, R M F ^a   Costa, M F D ^a   Costa, S L ^a   Clarencio J ^b   El Bacha, R S ^a  

^a FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Apoptosis; Bax; Bcl 2; Catechol; Cytotoxicity; Glioblastoma

Indexed keywords

AROMATIC COMPOUND; BENZENE; CATECHOL; DNA; GLUTATHIONE; LIPOCORTIN 5; PROTEIN BAX; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL LABELING; CELL NUCLEUS; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM; CHROMATIN; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DNA DAMAGE; EXPOSURE; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; METABOLITE; PRIORITY JOURNAL; TIME;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN NEOPLASMS; CATECHOLS; CELL LINE, TUMOR; CELL SHAPE; CELL SURVIVAL; CHROMATIN ASSEMBLY AND DISASSEMBLY; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; GLIOBLASTOMA; GLUTATHIONE; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; TIME FACTORS;

EID: 77749282900     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327109360364     Document Type: Article

References (47)

1. Wallace L. Environmental exposure to benzene: An update. Environ Health Perspect 1996 ; 104: 1129-1136.
2. James VB, Warren DA Toxic effects of solvents and vapors. In: Klassen CD (ed.) Casarett & Doulls Toxicology: The Basic Science of Poisons. McGraw-Hill: New York, 2001.
3. Snyder R., Witz G., Goldstein BD The toxicology of benzene. Environ Health Perspect 1993 ; 100: 293-306.
4. Ragan U., Snyder R. An update on benzene. Ann NY Acad Sci 1997 ; 837: 105-113.
5. Bergsagel DE, Wong O., Bergsagel PL, et al. Benzene and multiple myeloma: appraisal of the scientific evidence. Blood 1999 ; 94: 1174-1182.
6. Gut I., Nedelcheva V., Soucek P., Stopka P., Tichavska B. Cytochromes P450 in benzene metabolism and involvement of their metabolites and reactive oxygen species in toxicity. Environ Health Perspect 1996 ; 104: 1211-1218.
7. Hotz P., Carbonnelle P., Haufroid V., Tschopp A., Buchet JP, Lauwerys R. Biological monitoring of vehicle mechanics and other workers exposed to low concentrations of benzene. Int Arch Occ Environ Health 1997 ; 70: 29-40.
8. Verma Y., Kumar A., Rana SVS. Biological monitoring of exposure to benzene in traffic policemen of North India. Ind Health 2003 ; 41: 260-264.
9. Schweigert N., Zehnder AJB, Eggen RIL. Chemical properties of catechols and their molecular modes of toxic action in cells, from microorganisms to mammals. Environ Microbiol 2001 ; 3: 81-91.
10. Muller T., Kuhn W., Przuntek H. Therapy with central active catechol-O-methyltransferase (COMT)-inhibitors: is addition of monoamine oxidase (MAO)-inhibitors necessary to slow progress of neurodegenerative disorders? J Neural Transm Gen Sect 1993 ; 92: 187-195.
11. Zhu BT CNS dopamine oxidation and catecholO-methyltransferase: importance in the etiology, pharmacotherapy, and dietary prevention of Parkinsons disease. Int J Mol Med 2004 ; 13: 343-353.
12. Pereira MRG, de Oliveira ES, de Villar Faga, et al. Cytotoxicity of catechol towards human glioblastoma cells via superoxide and reactive quinones generation. J Bras Patol Clín 2004 ; 40: 281-286.
13. Fairbairn DW, Olive PL, ONeill KL The comet assay: a comprehensive review. Mutat Res 1995 ; 339: 37-59.
14. Planchenault T., Costa SL, Fages C., et al. Differential expression of laminin and fibronectin and of their related metalloproteinases in human glioma cell lines: relation to invasion. Neurosci Let 2001 ; 299: 140-144.
15. Hansen MB, Nielsen SE, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 1989 ; 12: 203-210.
16. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ Protein measurement with the folin phenol reagent. J Biol Chem 1951 ; 193: 265-275.
17. Rosenfeld G. Corante pancrömico para hematologia e citologia cl ínica: nova combinaçäo dos componentes de May Grunwald e do Giemsa num sö corante de emprego prático. Mem Inst Butantä 1947 ; 20: 329-335.
18. Movseyan VA, Yakovlev AG, Dabaghyan EA, Stoica BA, Faen AI Ceramide induces neuronal apoptosis through the caspase-9/caspase-3 pathway. Biochem Biophys Res Commun 2002 ; 299: 201-207.
19. Ribeiro DA, Pereira PCM, Marcondes-Machado J., Silva SB, Pessoa AWP, Salvador DMF Does toxoplasmosis cause DNA damage? An evaluation in isogenic mice under normal diet or dietary restriction. Mutat Res 2004 ; 559: 169-176.
20. Vermes I., Haanen C., Steffens-Nakken H., Reutelingsperger C. A novel assay for apoptosis: flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J Immunol Methods 1995 ; 184: 39-51.
21. Marfat A., Chambers RJ, Magee TV Ether derivatives useful as inhibitors of PDE4 isozymes. 2007 ; US Pat. Appl. 7183293.
22. Miller KL, Presta LG Multivalent antibodies and uses therefor. 2008 ; US Pat. Appl. 20080299120.
23. Shin M. -H, Jang J. -H, Surh Y. -J. Potential roles of NF-°B and ERK1/2 in cytoprotection against oxidative cell death induced by tetrahydropapaveroline. Free Radic Biol Med 2004 ; 36: 1185-1194.
24. Lipton SA, Satoh T. Neuroprotective compositions and methods. 2009 ; US Pat. Appl. 20090042980.
25. Barreto GES, dos Santos GS, Egito EST, El-Bachá RS Catechol inhibits FADH2-linked respiration in rat liver mitochondrial fraction. Acta Cir Bras 2005 ; 20: S72 - S77.
26. Barreto GES, de Oliveira ES, de Villar Faga, et al. Investigation of toxic factors affecting cells of rat brains exposed to 3-methylcatechol. Braz Arch Biol Technol 2007 ; 50: 839-849.
27. Willingham MC Cytochemical methods for the detection of apoptosis. J Histochem Cytochem 1999 ; 47: 1101-1109.
28. Deschesnes RG, Huot J., Valerie K., Landry J. Involvement of p38 in apoptosis-associated membraneblebbing and nuclear condensation. Mol Biol Cell 2001 ; 12: 1569-1582.
29. Yoshie Y., Ohshima H. Synergistic induction of DNA strand breakage caused by nitric oxide together with catecholamine: implications for neurodegenerative disease. Chem Res Toxicol 1997 ; 10: 1015-1022.
30. Chen-Levy Z., Nourse J., Cleary ML The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation. Mol Cell Biol 1989 ; 9: 701-710.
31. Alnemri ES, Robertson NM, Fernandes TF, Croce CM, Litwack G. Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells. Proc Natl Acad Sci USA 1992 ; 89: 7295-7299.
32. Monaghan P., Robertson D., Amos TAS, Dyer MJS, Mason DY, Greaves MS Ultrastructural localization o BCL-2 protein. J Histochem Cytochem 1992 ; 40: 1819-1825.
33. Krajevski S., Tanaka S., Takayama S., Schibler MJ, Fenton W., Reed JC Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitonchondrial membranes. Cancer Res 1993 ; 53: 4701-4714.
34. Lithgow T., van Driel R., Bertram JF, Strasser A. The protein product of the oncogene bcl-2 is a componente of the nuclear envelope, the endoplasmic reticulum, and the outer mitochondrial membrane. Cell Growth Differ 1994 ; 5: 411-417.
35. Sedlak TW, Oltvai ZN, Yang E., et al. Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci USA 1995 ; 92: 7834-7838.
36. Yang J., Liu X., Bhalla K., et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 1997 ; 275: 1129-1132.
37. Kluck RM, Bossy-Wetzel E., Green DR, Newmeyer DD The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997 ; 275: 1132-1136.
38. Mandal M., Adam L., Mendelsohn J., Kumar R. Nuclear targeting of Bax during apoptosis in huma colorectal cancer cells. Oncogene 1998 ; 17: 999-1007.
39. Wood DE, Newcomb EW Cleavage of Bax enhances its cell death function. Exp Cell Res 2000 ; 256: 375-382.
40. Karlsson J., Øra I., Pörn-Ares I., Påhlman S. Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53. Clin Cancer Res 2004 ; 10: 3179-3188.
41. Das A., Banik NL, Patel SJ, Ray SK Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities. Mol Cancer 2004 ; 3: 36-45.
42. Jeong S. -Y, Seol D. -W. The role of mitochondria in apoptosis. BMB Rep 2008 ; 41: 11-22.
43. Friess T., Klein C., Strein P., Umana P. Combination therapy of a type II anti-CD20 antibody with an anti-Bcl-2 active agent. 2009 ; US Pat. Appl. 20090098118.
44. Pereira CMF, Oliveira CR Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress. Free Radic Biol Med 1997 ; 23: 637-647.
45. Nishi T., Takahashi M., Ito H., Yoshihama I., Takada E., Mizuguchi J. Participation of Bcl-2/Bax-± in glutamate-induced apoptosis of human glioblastoma cells. J Neuro-Oncol 1999 ; 44: 109-117.
46. Hammond CL, Lee TK, Ballatori N. Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes. J Hepatol 2001 ; 34: 946-954.
47. Blakely RD, Nass R., Miller D. Assay for toxin induced neuronal degeneration and viability in C. elegans. 2009 ; US Pat. Appl. 7531713.