Expression of sialidase Neu2 in leukemic K562 cells induces apoptosis by impairing Bcr-Abl/Src kinases signaling

Journal of Biological Chemistry

Volumn 282, Issue 19, 2007, Pages 14364-14372

  Tringali, Cristina ^a   Lupo, Barbara ^a   Anastasia, Luigi ^a   Papini, Nadia ^a   Monti, Eugenio ^b   Bresciani, Roberto ^b   Tettamanti, Guido ^a   Venerando, Bruno ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; ENZYME ACTIVITY; GENE EXPRESSION; GLYCOPROTEINS; RNA;

LEUKEMIA; NEU2 TRANSFECTION; SIALIC ACID;

TUMORS;

BCR ABL PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GLYCOPROTEIN; MESSENGER RNA; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE LYN; PROTEIN TYROSINE KINASE; SIALIC ACID; SIALIDASE; LYN PROTEIN-TYROSINE KINASE; NEU2 PROTEIN, HUMAN; PROTEIN BCL X; PROTEIN KINASE P60; SPHINGOLIPID; TYROSINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME REPRESSION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA; MOLECULAR WEIGHT; MYELOID LEUKEMIA; ONCOGENE NEU; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION; CELL STRAIN K 562; DOWN REGULATION; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APOPTOSIS; BCL-X PROTEIN; BLOTTING, WESTERN; CELL PROLIFERATION; DOWN-REGULATION; FLUORESCENT ANTIBODY TECHNIQUE; FUSION PROTEINS, BCR-ABL; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; K562 CELLS; NEURAMINIDASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS PP60(C-SRC); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; SRC-FAMILY KINASES; TYROSINE;

EID: 34347207593     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700406200     Document Type: Article

References (53)

1. Bremer, E., van Dam, G., Kroesen, B. J., de Leij, L., and Helfrich, W. (2006) Trends Mol. Med 12, 382-393
2. Debatin, K. M. (2004) Cancer Immunol. Immunother. 53, 153-159
3. Papadopoulos, K. (2006) Semin Oncol. 33, 449-456
4. Groffen, J., Stephenson, J. R., Heisterkamp, N., de Klein, A., Bartram, C. R., and Grosveld, G. (1984) Cell 36, 93-99
5. Shtivelman, E., Lifshitz, B., Gale, R. P., and Canaani, E. (1985) Nature 315, 550-554
6. Ren, R. (2005) Nat. Rev. Cancer 5, 172-183
7. Inokuchi, K. (2006) J. Nippon Med. Sch. 73, 178-192
8. Pasternak, G., Hochhaus, A., Schultheis, B., and Hehlmann, R. (1998) J. Cancer Res. Clin. Oncol. 124, 643-660
9. Fernandez-Luna, J. L. (2000) Apoptosis 5, 315-318
10. Melo, J., and Barnes, D. J. (2004) Hematol J. 5, (Suppl. 3) S183-S187
11. Deininger, M. W., Goldman, J. M., and Melo, J. V. (2000) Blood 96, 3343-3356
12. Salesse, S., and Verfaillie, C. M. (2003) Mol. Cancer Ther. 2, 173-182
13. Fuster, M. M., and Esko, J. D. (2005) Nat. Rev. Cancer 5, 526-542
14. Dube, D. H., and Bertozzi, C. R. (2005) Nat. Rev. Drug Discov. 4, 477-488
15. Hakomori, S. (1996) Cancer Res. 56, 5309-5318
16. Wells, L., Vosseller, K., and Hart, G. W. (2001) Science 291, 2376-2378
17. Allende, M. L., and Proia, R. L. (2002) Curr. Opin. Struct. Biol. 12, 587-592
18. Lin, C. F., Chen, C. L., and Lin, Y. S. (2006) Curr. Med. Chem. 13, 1609-1616
19. Miyagi, T., Wada, T., Yamaguchi, K., and Hata, K. (2004) Glycoconj. J. 20, 189-198
20. Achyuthan, K. E., and Achyuthan, A. M. (2001) Comp. Biochem. Physiol. B Biochem. Mol. Biol. 129, 29-64
21. Monti, E., Preti, A., Venerando, B., and Borsani, G. (2002) Neurochem. Res. 27, 649-663
22. Yamaguchi, K., Hata, K., Koseki, K., Shiozaki, K., Akita, H., Wada, T., Moriya, S., and Miyagi, T. (2005) Biochem. J. 390, (Pt 1), 85-93
23. Kato, T., Wang, Y., Yamaguchi, K., Milner, C. M., Shineha, R., Satomi, S., and Miyagi, T. (2001) Int. J. Cancer 92, 797-804
24. Kakugawa, Y., Wada, T., Yamaguchi, K., Yamanami, H., Ouchi, K., Sato, I., and Miyagi, T. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 10718-10723
25. Ueno, S., Saito, S., Wada, T., Yamaguchi, K., Satoh, M., Arai, Y., and Miyagi, T. (2006) J. Biol. Chem. 281, 7756-7764
26. Kato, K., Shiga, K., Yamaguchi, K., Hata, K., Kobayashi, T., Miyazaki, K., Saijo, S., and Miyagi, T. (2006) Biochem. J. 394, 647-656
27. Tokuyama, S., Moriya, S., Taniguchi, S., Yasui, A., Miyazaki, J., Orikasa, S., and Miyagi, T. (1997) Int. J. Cancer 73, 410-415
28. Sawada, M., Moriya, S., Saito, S., Shineha, R., Satomi, S., Yamori, T., Tsuruo, T., Kannagi, R., and Miyagi, T. (2002) Int. J. Cancer 97, 180-185
29. Tringali, C., Anastasia, L., Papini, N., Bianchi, A., Ronzoni, L., Cappellini, M. D., Monti, E., Tettamanti, G., and Venerando, B. (2006) Glycoconj. J. 24, 67-79
30. Monti, E., Preti, A., Nesti, C., Ballabio, A., and Borsani, G. (1999) Glycobiology 9, 1313-1321
31. Carter, H. E., Brooks, S., Gigg, R. H., Strobach, D. R., and Suami, T. (1964) J. Biol. Chem. 239, 743-746
32. Zhang, Y., Toyokuni, T., Ruan, F., and Hakomori, S. I. (2001) Glycoconj. J. 18, 557-563
33. Tettamanti, G., Bonali, F., Marchesini, S., and Zambotti, V. (1973) Biochim. Biophys. Acta 296, 160-170
34. Sonnino, S., Nicolini, M., and Chigorno, V. (1996) Glycobiology 6, 479-487
35. Sonnino, S., Ghidoni, R., Gazzotti, G., Kirschner, G., Galli, G., and Tettamanti, G. (1984) J. Lipid Res. 25, 620-629
36. Tringali, C., Papini, N., Fusi, P., Croci, G., Borsani, G., Preti, A., Tortora, P., Tettamanti, G., Venerando, B., and Monti, E. (2004) J. Biol. Chem. 279, 3169-3179
37. Bossy-Wetzel, E., Newmeyer, D. D., and Green, D. R. (1998) EMBO J. 17, 37-49
38. Papini, N., Anastasia, L., Tringali, C., Croci, G., Bresciani, R., Yamaguchi, K., Miyagi, T., Preti, A., Prinetti, A., Prioni, S., Sonnino, S., Tettamanti, G., Venerando, B., and Monti, E. (2004) J. Biol. Chem. 279, 16989-16995
39. Chavas, L. M., Tringali, C., Fusi, P., Venerando, B., Tettamanti, G., Kato, R., Monti, E., and Wakatsuki, S. (2005) J. Biol. Chem. 280, 469-475
40. Wilson, M. B., Schreiner, S. J., Choi, H. J., Kamens, J., and Smithgall, T. E. (2002) Oncogene 21, 8075-8088
41. Donato, N. J., Wu, J. Y., Stapley, J., Gallick, G., Lin, H., Arlinghaus, R., and Talpaz, M. (2003) Blood 101, 690-698
42. Dai, Y., Rahmani, M., Corey, S. J., Dent, P., and Grant, S. (2004) J. Biol. Chem. 279, 34227-34239
43. Meyn, M. A., IIII, Wilson, M. B., Abdi, F. A., Fahey, N., Schiavone, A. P., Wu, J., Hochrein, J. M., Engen, J. R., and Smithgall, T. E. (2006) J. Biol. Chem. 281, 30907-30916
44. Roginskaya, V., Zuo, S., Caudell, E., Nambudiri, G., Kraker, A. J., and Corey, S. J. (1999) Leukemia 13, 855-861
45. Porter, M., Schindler, T., Kuriyan, J., and Miller, W. T. (2000) J. Biol. Chem. 275, 2721-2726
46. Sato, K., and Miyagi, T. (1996) Biochem. Biophys. Res. Commun. 221, 826-830
47. Fanzani, A., Giuliani, R., Colombo, F., Zizioli, D., Presta, M., Preti, A., and Marchesini, S. (2003) FEBS Lett. 547, 183-188
48. Chen, R., Gandhi, V., and Plunkett, W. (2006) Cancer Res. 66, 10959-10966
49. Danhauser-Riedl, S., Warmuth, M., Druker, B. J., Emmerich, B., and Hallek, M. (1996) Cancer Res. 56, 3589-3596
50. Ptasznik, A., Nakata, Y., Kalota, A., Emerson, S. G., and Gewirtz, A. M. (2004) Nat. Med 10, 1187-1189
51. Dai, Z., and Pendergast, A. M. (1995) Genes Dev. 9, 2569-2582
52. Shi, Y., Alin, K., and Goff, S. P. (1995) Genes Dev. 9, 2583-2597
53. Dai, Z., Quackenbush, R. C., Courtney, K. D., Grove, M., Cortez, D., Reuther, G. W., and Pendergast, A. M. (1998) Genes Dev. 12, 1415-1424