Suppressive effects of 1-[4-fluoro-2-(2-nitrovinyl)phenyl]pyrrolidine on the Toll-like receptor signaling pathways

International Immunopharmacology

Volumn 24, Issue 1, 2015, Pages 36-41

  Ahn, Sang Il ^a   Lim, Se Jin ^a   Gu, Gyo Jeong ^a   Hong, Chae Yeon ^a   Kim, Ji Soo ^a   Jeong, Hyun Jung ^a   Koh, Kwang Oh ^a   Mang, Joo Yang ^a   Kim, Dae Young ^a   Youn, Hyung Sun ^a  

^a Soonchunhyang University   (South Korea)

Author keywords

Cyclooxygenase 2; Inducible nitric oxide synthase; IRF3; NF B; Toll like receptor

Indexed keywords

1 [4 FLUORO 2 (2 NITROVINYL)PHENYL]PYRROLIDINE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1 RECEPTOR; PYRROLIDINE DERIVATIVE; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; 1-(4-FLUORO-2-(2-NITROVINYL)PHENYL)PYRROLIDINE; IRF3 PROTEIN, MOUSE; NONSTEROID ANTIINFLAMMATORY AGENT; PTGS2 PROTEIN, MOUSE; VINYL DERIVATIVE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; ENZYME ACTIVATION; GENE OVEREXPRESSION; HEK293 CELL LINE; HUMAN; HUMAN CELL; MONOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENETICS; INFLAMMATION; METABOLISM;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CHEMOKINE CXCL10; CYCLOOXYGENASE 2; DOWN-REGULATION; HUMANS; INFLAMMATION; INTERFERON REGULATORY FACTOR-3; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PYRROLIDINES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; VINYL COMPOUNDS;

EID: 84911937181     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.10.033     Document Type: Article

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