RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 46, 2014, Pages 13389-16394

  Kim, Woosook ^a   Barron, David A ^a,b   Martin, Rebeca San ^a   Chan, Keith S ^a   Tran, Linda L ^a   Yang, Feng ^a   Ressler, Steven J ^a,c   Rowley, David R ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c Aptalis Pharmaceuticals   (United States)

Author keywords

MSC; Myofibroblast; Reactive stroma; RUNX1; TGF 1

Indexed keywords

HERMES ANTIGEN; THY 1 ANTIGEN; TRANSCRIPTION FACTOR RUNX1; RUNX1 PROTEIN, HUMAN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR PROTEIN;

ARTICLE; CANCER CELL; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CELL INTERACTION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MALE; MESENCHYMAL STEM CELL; MYOFIBROBLAST; PROSTATE; PROSTATE CANCER; PROTEIN FUNCTION; ADENOCARCINOMA; ADULT; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE MARROW CELL; CELL DIVISION; CELL LINE; CELL LINEAGE; COCULTURE; CYTOLOGY; CYTOPLASM; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MESENCHYMAL STROMA CELL; MOUSE; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; PROSTATE TUMOR; STROMA CELL; TUMOR CELL LINE; YOUNG ADULT;

ADENOCARCINOMA; ADULT; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CELL LINE, TUMOR; CELL LINEAGE; COCULTURE TECHNIQUES; CORE BINDING FACTOR ALPHA 2 SUBUNIT; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, NUDE; MYOFIBROBLASTS; NEOPLASM PROTEINS; ORGANOIDS; PROSTATE; PROSTATIC NEOPLASMS; RNA, SMALL INTERFERING; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA1; YOUNG ADULT;

EID: 84911908834     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1407097111     Document Type: Article

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