메뉴 건너뛰기




Volumn 15, Issue 7, 2014, Pages 12665-12676

Transforming Growth Factor-β1 (TGF-β1) Induces Mouse Precartilaginous Stem Cell Proliferation through TGF-β Receptor II (TGFRII)-Akt-β-Catenin Signaling

Author keywords

Akt; Chondrogenesis; Precartilaginous stem cells; Proliferation; catenin and signaling; TGF 1

Indexed keywords

BETA CATENIN; PROTEIN KINASE B; THYMIDINE; TRANSFORMING GROWTH FACTOR BETA1; CYCLIN D1; FGFR3 PROTEIN, MOUSE; FIBROBLAST GROWTH FACTOR RECEPTOR 3; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MYC PROTEIN;

EID: 84904480149     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150712665     Document Type: Article
Times cited : (16)

References (43)
  • 2
    • 57149112607 scopus 로고    scopus 로고
    • Immunological purification of rat precartilaginous stem cells and construction of the immortalized cell strain
    • Zhang, S.; Chen, A.; Hu, W.; Li, M.; Liao, H.; Zhu, W.; Song, D.; Guo, F. Immunological purification of rat precartilaginous stem cells and construction of the immortalized cell strain. Arch. Orthop. Trauma Surg. 2008, 128, 1339-1344.
    • (2008) Arch. Orthop. Trauma Surg. , vol.128 , pp. 1339-1344
    • Zhang, S.1    Chen, A.2    Hu, W.3    Li, M.4    Liao, H.5    Zhu, W.6    Song, D.7    Guo, F.8
  • 4
    • 84884222595 scopus 로고    scopus 로고
    • Chondrogenic effect of precartilaginous stem cells following NLS-TAT cell penetrating peptide-assisted transfection of eukaryotic hTGFbeta3
    • Guo, X.; Chu, X.; Li, W.; Pan, Q.; You, H. Chondrogenic effect of precartilaginous stem cells following NLS-TAT cell penetrating peptide-assisted transfection of eukaryotic hTGFbeta3. J. Cell. Biochem. 2013, 114, 2588-2594.
    • (2013) J. Cell. Biochem. , vol.114 , pp. 2588-2594
    • Guo, X.1    Chu, X.2    Li, W.3    Pan, Q.4    You, H.5
  • 5
    • 58149239733 scopus 로고    scopus 로고
    • Roles of TGF-beta family signaling in stem cell renewal and differentiation
    • Watabe, T.; Miyazono, K. Roles of TGF-beta family signaling in stem cell renewal and differentiation. Cell Res. 2009, 19, 103-115.
    • (2009) Cell Res. , vol.19 , pp. 103-115
    • Watabe, T.1    Miyazono, K.2
  • 6
    • 4644245693 scopus 로고    scopus 로고
    • Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin
    • Erlebacher, A.; Price, K. A.; Glimcher, L. H. Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin. Dev. Biol. 2004, 275, 158-169.
    • (2004) Dev. Biol. , vol.275 , pp. 158-169
    • Erlebacher, A.1    Price, K.A.2    Glimcher, L.H.3
  • 7
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi, Y.; Massague, J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003, 113, 685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 8
    • 0032763469 scopus 로고    scopus 로고
    • Specificity, diversity, and regulation in TGF-beta superfamily signaling
    • Piek, E.; Heldin, C. H.; ten Dijke, P. Specificity, diversity, and regulation in TGF-beta superfamily signaling. FASEB J. 1999, 13, 2105-2124.
    • (1999) FASEB J. , vol.13 , pp. 2105-2124
    • Piek, E.1    Heldin, C.H.2    ten Dijke, P.3
  • 9
    • 58149213801 scopus 로고    scopus 로고
    • Non-Smad pathways in TGF-beta signaling
    • Zhang, Y. E. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009, 19, 128-139.
    • (2009) Cell Res. , vol.19 , pp. 128-139
    • Zhang, Y.E.1
  • 11
    • 0042704734 scopus 로고    scopus 로고
    • Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells
    • Hayashida, T.; Decaestecker, M.; Schnaper, H. W. Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells. FASEB J. 2003, 17, 1576-1578.
    • (2003) FASEB J. , vol.17 , pp. 1576-1578
    • Hayashida, T.1    Decaestecker, M.2    Schnaper, H.W.3
  • 12
    • 2342471301 scopus 로고    scopus 로고
    • Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis
    • Conery, A. R.; Cao, Y.; Thompson, E. A.; Townsend, C. M., Jr.; Ko, T. C.; Luo, K. Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis. Nat. Cell Biol. 2004, 6, 366-372.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 366-372
    • Conery, A.R.1    Cao, Y.2    Thompson, E.A.3    Townsend Jr., C.M.4    Ko, T.C.5    Luo, K.6
  • 13
    • 2342647439 scopus 로고    scopus 로고
    • PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3
    • Remy, I.; Montmarquette, A.; Michnick, S. W. PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3. Nat. Cell Biol. 2004, 6, 358-365.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 358-365
    • Remy, I.1    Montmarquette, A.2    Michnick, S.W.3
  • 15
    • 34547587877 scopus 로고    scopus 로고
    • Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway
    • Lamouille, S.; Derynck, R. Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway. J. Cell Biol. 2007, 178, 437-451.
    • (2007) J. Cell Biol. , vol.178 , pp. 437-451
    • Lamouille, S.1    Derynck, R.2
  • 16
    • 84863512851 scopus 로고    scopus 로고
    • Beta-2 spectrin is involved in hepatocyte proliferation through the interaction of TGFbeta/Smad and PI3K/AKT signalling
    • Wang, Z.; Song, Y.; Tu, W.; He, X.; Lin, J.; Liu, F. Beta-2 spectrin is involved in hepatocyte proliferation through the interaction of TGFbeta/Smad and PI3K/AKT signalling. Liver Int. 2012, 32, 1103-1111.
    • (2012) Liver Int. , vol.32 , pp. 1103-1111
    • Wang, Z.1    Song, Y.2    Tu, W.3    He, X.4    Lin, J.5    Liu, F.6
  • 17
    • 0037167792 scopus 로고    scopus 로고
    • Autocrine TGFbeta supports growth and survival of human breast cancer MDA-MB-231 cells
    • Lei, X.; Bandyopadhyay, A.; Le, T.; Sun, L. Autocrine TGFbeta supports growth and survival of human breast cancer MDA-MB-231 cells. Oncogene 2002, 21, 7514-7523.
    • (2002) Oncogene , vol.21 , pp. 7514-7523
    • Lei, X.1    Bandyopadhyay, A.2    Le, T.3    Sun, L.4
  • 18
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • Derynck, R.; Akhurst, R. J.; Balmain, A. TGF-beta signaling in tumor suppression and cancer progression. Nat. Genet. 2001, 29, 117-129.
    • (2001) Nat. Genet. , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 20
    • 84873048662 scopus 로고    scopus 로고
    • Wnt/beta-catenin signalling: From plasma membrane to nucleus
    • Kim, W.; Kim, M.; Jho, E. H. Wnt/beta-catenin signalling: From plasma membrane to nucleus. Biochem. J. 2013, 450, 9-21.
    • (2013) Biochem. J. , vol.450 , pp. 9-21
    • Kim, W.1    Kim, M.2    Jho, E.H.3
  • 21
    • 84055222589 scopus 로고    scopus 로고
    • The Wnt/beta-catenin signaling pathway: A potential therapeutic target in the treatment of triple negative breast cancer
    • King, T. D.; Suto, M. J.; Li, Y. The Wnt/beta-catenin signaling pathway: A potential therapeutic target in the treatment of triple negative breast cancer. J. Cell. Biochem. 2012, 113, 13-18.
    • (2012) J. Cell. Biochem. , vol.113 , pp. 13-18
    • King, T.D.1    Suto, M.J.2    Li, Y.3
  • 22
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald, B. T.; Tamai, K.; He, X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 2009, 17, 9-26.
    • (2009) Dev. Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 23
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle, H.; Bauer, A.; Stappert, J.; Kispert, A.; Kemler, R. Beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 1997, 16, 3797-3804.
    • (1997) EMBO J. , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 24
    • 84864877553 scopus 로고    scopus 로고
    • Wnt/beta-catenin signalling in prostate cancer
    • Kypta, R. M.; Waxman, J. Wnt/beta-catenin signalling in prostate cancer. Nat. Rev. Urol. 2012, 9, 418-428.
    • (2012) Nat. Rev. Urol. , vol.9 , pp. 418-428
    • Kypta, R.M.1    Waxman, J.2
  • 25
    • 84877583717 scopus 로고    scopus 로고
    • Looking beyond the Wnt pathway for the deep nature of beta-catenin
    • Fagotto, F. Looking beyond the Wnt pathway for the deep nature of beta-catenin. EMBO Rep. 2013, 14, 422-433.
    • (2013) EMBO Rep. , vol.14 , pp. 422-433
    • Fagotto, F.1
  • 26
    • 84875743289 scopus 로고    scopus 로고
    • A Wnt-er migration: The confusing role of beta-catenin in melanoma metastasis
    • doi: 10. 1126/scisignal. 2004114
    • Webster, M. R.; Weeraratna, A. T. A Wnt-er migration: The confusing role of beta-catenin in melanoma metastasis. Sci. Signal. 2013, doi: 10. 1126/scisignal. 2004114.
    • (2013) Sci. Signal.
    • Webster, M.R.1    Weeraratna, A.T.2
  • 30
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu, O.; McCormick, F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398, 422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 32
    • 33750936779 scopus 로고    scopus 로고
    • Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells
    • Gadue, P.; Huber, T. L.; Paddison, P. J.; Keller, G. M. Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proc. Natl. Acad. Sci. USA 2006, 103, 16806-16811.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16806-16811
    • Gadue, P.1    Huber, T.L.2    Paddison, P.J.3    Keller, G.M.4
  • 33
    • 33645007189 scopus 로고    scopus 로고
    • Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells
    • Jian, H.; Shen, X.; Liu, I.; Semenov, M.; He, X.; Wang, X. F. Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells. Genes Dev. 2006, 20, 666-674.
    • (2006) Genes Dev. , vol.20 , pp. 666-674
    • Jian, H.1    Shen, X.2    Liu, I.3    Semenov, M.4    He, X.5    Wang, X.F.6
  • 34
  • 35
    • 62849106337 scopus 로고    scopus 로고
    • Beta-catenin hits chromatin: Regulation of Wnt target gene activation
    • Mosimann, C.; Hausmann, G.; Basler, K. Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat. Rev. Mol. Cell Biol. 2009, 10, 276-286.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 276-286
    • Mosimann, C.1    Hausmann, G.2    Basler, K.3
  • 36
    • 60349088457 scopus 로고    scopus 로고
    • Perifosine: Update on a novel Akt inhibitor
    • Gills, J. J.; Dennis, P. A. Perifosine: Update on a novel Akt inhibitor. Curr. Oncol. Rep. 2009, 11, 102-110.
    • (2009) Curr. Oncol. Rep. , vol.11 , pp. 102-110
    • Gills, J.J.1    Dennis, P.A.2
  • 37
    • 77954615408 scopus 로고    scopus 로고
    • MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo
    • Hirai, H.; Sootome, H.; Nakatsuru, Y.; Miyama, K.; Taguchi, S.; Tsujioka, K.; Ueno, Y.; Hatch, H.; Majumder, P. K.; Pan, B. S.; et al. MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo. Mol. Cancer Ther. 2010, 9, 1956-1967.
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 1956-1967
    • Hirai, H.1    Sootome, H.2    Nakatsuru, Y.3    Miyama, K.4    Taguchi, S.5    Tsujioka, K.6    Ueno, Y.7    Hatch, H.8    Majumder, P.K.9    Pan, B.S.10
  • 38
    • 33748153690 scopus 로고    scopus 로고
    • TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
    • Inoki, K.; Ouyang, H.; Zhu, T.; Lindvall, C.; Wang, Y.; Zhang, X.; Yang, Q.; Bennett, C.; Harada, Y.; Stankunas, K.; et al. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 2006, 126, 955-968.
    • (2006) Cell , vol.126 , pp. 955-968
    • Inoki, K.1    Ouyang, H.2    Zhu, T.3    Lindvall, C.4    Wang, Y.5    Zhang, X.6    Yang, Q.7    Bennett, C.8    Harada, Y.9    Stankunas, K.10
  • 39
    • 84957591389 scopus 로고    scopus 로고
    • Roles of Wnt/beta-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment
    • 2014, doi: 10. 1038/cddis. 515
    • Mao, J.; Fan, S.; Ma, W.; Fan, P.; Wang, B.; Zhang, J.; Wang, H.; Tang, B.; Zhang, Q.; Yu, X.; et al. Roles of Wnt/beta-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment. Cell Death Dis. 2014, doi: 10. 1038/cddis. 2013. 515.
    • (2013) Cell Death Dis.
    • Mao, J.1    Fan, S.2    Ma, W.3    Fan, P.4    Wang, B.5    Zhang, J.6    Wang, H.7    Tang, B.8    Zhang, Q.9    Yu, X.10
  • 40
    • 84897431613 scopus 로고    scopus 로고
    • The Combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: Involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway
    • Ji, D.; Zhang, Z.; Cheng, L.; Chang, J.; Wang, S.; Zheng, B.; Zheng, R.; Sun, Z.; Wang, C.; Liu, R.; et al. The Combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: Involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway. PLoS One 2014, 9, e85116.
    • (2014) PLoS One , vol.9
    • Ji, D.1    Zhang, Z.2    Cheng, L.3    Chang, J.4    Wang, S.5    Zheng, B.6    Zheng, R.7    Sun, Z.8    Wang, C.9    Liu, R.10
  • 42
    • 49749086530 scopus 로고    scopus 로고
    • A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation
    • Yu, Z.; Wang, C.; Wang, M.; Li, Z.; Casimiro, M. C.; Liu, M.; Wu, K.; Whittle, J.; Ju, X.; Hyslop, T.; et al. A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J. Cell Biol. 2008, 182, 509-517.
    • (2008) J. Cell Biol. , vol.182 , pp. 509-517
    • Yu, Z.1    Wang, C.2    Wang, M.3    Li, Z.4    Casimiro, M.C.5    Liu, M.6    Wu, K.7    Whittle, J.8    Ju, X.9    Hyslop, T.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.