메뉴 건너뛰기




Volumn 19, Issue 10, 2014, Pages 16588-16608

Deguelin inhibits the migration and invasion of U-2 OS human osteosarcoma cells via the inhibition of matrix metalloproteinase-2/-9 in vitro

Author keywords

Deguelin; Invasion; Migration; U 2 OS human osteosarcoma cells

Indexed keywords

DEGUELIN; GELATINASE A; GELATINASE B; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; ROTENONE;

EID: 84911883543     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules191016588     Document Type: Article
Times cited : (45)

References (50)
  • 3
    • 79960898302 scopus 로고    scopus 로고
    • Imaging pediatric bone sarcomas
    • Kaste, S.C. Imaging pediatric bone sarcomas. Radiol. Clin. North Am. 2011, 49, 749-765.
    • (2011) Radiol. Clin. North Am. , vol.49 , pp. 749-765
    • Kaste, S.C.1
  • 6
    • 3543035771 scopus 로고    scopus 로고
    • Biology and therapeutic advances for pediatric osteosarcoma
    • Marina, N.; Gebhardt, M.; Teot, L.; Gorlick, R. Biology and therapeutic advances for pediatric osteosarcoma. Oncologist 2004, 9, 422-441.
    • (2004) Oncologist , vol.9 , pp. 422-441
    • Marina, N.1    Gebhardt, M.2    Teot, L.3    Gorlick, R.4
  • 7
    • 78649944462 scopus 로고    scopus 로고
    • Osteosarcoma: A review of diagnosis, management, and treatment strategies
    • Geller, D.S.; Gorlick, R. Osteosarcoma: A review of diagnosis, management, and treatment strategies. Clin. Adv. Hematol. Oncol. 2010, 8, 705-718.
    • (2010) Clin. Adv. Hematol. Oncol. , vol.8 , pp. 705-718
    • Geller, D.S.1    Gorlick, R.2
  • 8
    • 78649839006 scopus 로고    scopus 로고
    • Follow the leader: LIM kinases pave the way for collective tumor cell invasion
    • Olson, M.F. Follow the leader: LIM kinases pave the way for collective tumor cell invasion. Cell Cycle 2010, 9, 4417-4418.
    • (2010) Cell Cycle , vol.9 , pp. 4417-4418
    • Olson, M.F.1
  • 10
    • 0035190793 scopus 로고    scopus 로고
    • Cellular and molecular properties associated with osteosarcoma cells
    • Benayahu, D.; Shur, I.; Marom, R.; Meller, I.; Issakov, J. Cellular and molecular properties associated with osteosarcoma cells. J. Cell. Biochem. 2001, 84, 108-114.
    • (2001) J. Cell. Biochem. , vol.84 , pp. 108-114
    • Benayahu, D.1    Shur, I.2    Marom, R.3    Meller, I.4    Issakov, J.5
  • 11
    • 0027968219 scopus 로고
    • Binding and activation of plasminogen on the surface of osteosarcoma cells
    • Campbell, P.G.; Wines, K.; Yanosick, T.B.; Novak, J.F. Binding and activation of plasminogen on the surface of osteosarcoma cells. J. Cell. Physiol. 1994, 159, 1-10.
    • (1994) J. Cell. Physiol. , vol.159 , pp. 1-10
    • Campbell, P.G.1    Wines, K.2    Yanosick, T.B.3    Novak, J.F.4
  • 12
    • 0025953488 scopus 로고
    • Cell proliferation rate and tumor volume in human osteosarcoma during exposure to methotrexate. A study on tissue transplants in nude mice
    • Smeds, S.; Walz, T.; Blomquist, L.; Larsson, S.E. Cell proliferation rate and tumor volume in human osteosarcoma during exposure to methotrexate. A study on tissue transplants in nude mice. APMIS 1991, 99, 898-904.
    • (1991) APMIS , vol.99 , pp. 898-904
    • Smeds, S.1    Walz, T.2    Blomquist, L.3    Larsson, S.E.4
  • 13
    • 77955496138 scopus 로고    scopus 로고
    • Arsenic trioxide inhibits osteosarcoma cell invasiveness via MAPK signaling pathway
    • Tingting, R.; Wei, G.; Changliang, P.; Xinchang, L.; Yi, Y. Arsenic trioxide inhibits osteosarcoma cell invasiveness via MAPK signaling pathway. Cancer Biol. Ther. 2010, 10, 251-257.
    • (2010) Cancer Biol. Ther. , vol.10 , pp. 251-257
    • Tingting, R.1    Wei, G.2    Changliang, P.3    Xinchang, L.4    Yi, Y.5
  • 14
    • 79955745583 scopus 로고    scopus 로고
    • MMP9 mediates MICA shedding in human osteosarcomas
    • Sun, D.; Wang, X.; Zhang, H.; Deng, L.; Zhang, Y. MMP9 mediates MICA shedding in human osteosarcomas. Cell Biol. Int. 2011, 35, 569-574.
    • (2011) Cell Biol. Int. , vol.35 , pp. 569-574
    • Sun, D.1    Wang, X.2    Zhang, H.3    Deng, L.4    Zhang, Y.5
  • 15
  • 16
    • 78650824229 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma
    • Korpi, J.T.; Hagstrom, J.; Lehtonen, N.; Parkkinen, J.; Sorsa, T.; Salo, T.; Laitinen, M. Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma. Surg. Oncol. 2011, 20, e18-e22.
    • (2011) Surg. Oncol. , vol.20 , pp. e18-e22
    • Korpi, J.T.1    Hagstrom, J.2    Lehtonen, N.3    Parkkinen, J.4    Sorsa, T.5    Salo, T.6    Laitinen, M.7
  • 20
    • 0037430197 scopus 로고    scopus 로고
    • Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice
    • Murillo, G.; Kosmeder, J.W.; Pezzuto, J.M.; Mehta, R.G. Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice. Int. J. Cancer 2003, 104, 7-11.
    • (2003) Int. J. Cancer , vol.104 , pp. 7-11
    • Murillo, G.1    Kosmeder, J.W.2    Pezzuto, J.M.3    Mehta, R.G.4
  • 22
    • 33644874504 scopus 로고    scopus 로고
    • Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice
    • Yan, Y.; Wang, Y.; Tan, Q.; Lubet, R.A.; You, M. Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. Neoplasia 2005, 7, 1053-1057.
    • (2005) Neoplasia , vol.7 , pp. 1053-1057
    • Yan, Y.1    Wang, Y.2    Tan, Q.3    Lubet, R.A.4    You, M.5
  • 23
    • 1042278720 scopus 로고    scopus 로고
    • Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells
    • Lee, H.Y.; Suh, Y.A.; Kosmeder, J.W.; Pezzuto, J.M.; Hong, W.K.; Kurie, J.M. Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells. Clin. Cancer Res. 2004, 10, 1074-1079.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1074-1079
    • Lee, H.Y.1    Suh, Y.A.2    Kosmeder, J.W.3    Pezzuto, J.M.4    Hong, W.K.5    Kurie, J.M.6
  • 24
    • 33749524818 scopus 로고    scopus 로고
    • Deguelin an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion
    • Nair, A.S.; Shishodia, S.; Ahn, K.S.; Kunnumakkara, A.B.; Sethi, G.; Aggarwal, B.B. Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. J. Immunol. 2006, 177, 5612-5622.
    • (2006) J. Immunol. , vol.177 , pp. 5612-5622
    • Nair, A.S.1    Shishodia, S.2    Ahn, K.S.3    Kunnumakkara, A.B.4    Sethi, G.5    Aggarwal, B.B.6
  • 25
    • 0036892114 scopus 로고    scopus 로고
    • Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest
    • Murillo, G.; Salti, G.I.; Kosmeder, J.W.; Pezzuto, J.M.; Mehta, R.G. Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. Eur. J. Cancer 2002, 38, 2446-2454.
    • (2002) Eur. J. Cancer , vol.38 , pp. 2446-2454
    • Murillo, G.1    Salti, G.I.2    Kosmeder, J.W.3    Pezzuto, J.M.4    Mehta, R.G.5
  • 26
    • 84863016361 scopus 로고    scopus 로고
    • Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells
    • Ji, B.C.; Yu, C.C.; Yang, S.T.; Hsia, T.C.; Yang, J.S.; Lai, K.C.; Ko, Y.C.; Lin, J.J.; Lai, T.Y.; Chung, J.G. Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells. Oncol. Rep. 2012, 27, 959-964.
    • (2012) Oncol. Rep. , vol.27 , pp. 959-964
    • Ji, B.C.1    Yu, C.C.2    Yang, S.T.3    Hsia, T.C.4    Yang, J.S.5    Lai, K.C.6    Ko, Y.C.7    Lin, J.J.8    Lai, T.Y.9    Chung, J.G.10
  • 27
    • 84867086656 scopus 로고    scopus 로고
    • Assessment of gelatinases (MMP-2 and MMP-9) by gelatin zymography
    • Toth, M.; Sohail, A.; Fridman, R. Assessment of gelatinases (MMP-2 and MMP-9) by gelatin zymography. Methods Mol. Biol. 2012, 878, 121-135.
    • (2012) Methods Mol. Biol. , vol.878 , pp. 121-135
    • Toth, M.1    Sohail, A.2    Fridman, R.3
  • 28
    • 84879414971 scopus 로고    scopus 로고
    • Integrin beta5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways
    • Bianchi-Smiraglia, A.; Paesante, S.; Bakin, A.V. Integrin beta5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways. Oncogene 2012, 32, 3049-3058.
    • (2012) Oncogene , vol.32 , pp. 3049-3058
    • Bianchi-Smiraglia, A.1    Paesante, S.2    Bakin, A.V.3
  • 29
    • 84857138655 scopus 로고    scopus 로고
    • NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCiota/FAK loop
    • Shen, J.; Xu, L.; Owonikoko, T.K.; Sun, S.Y.; Khuri, F.R.; Curran, W.J.; Deng, X. NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCiota/FAK loop. Cancer Lett. 2012, 318, 106-113.
    • (2012) Cancer Lett. , vol.318 , pp. 106-113
    • Shen, J.1    Xu, L.2    Owonikoko, T.K.3    Sun, S.Y.4    Khuri, F.R.5    Curran, W.J.6    Deng, X.7
  • 30
    • 0033612572 scopus 로고    scopus 로고
    • Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle
    • Oktay, M.; Wary, K.K.; Dans, M.; Birge, R.B.; Giancotti, F.G. Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. J. Cell Biol. 1999, 145, 1461-1469.
    • (1999) J. Cell Biol. , vol.145 , pp. 1461-1469
    • Oktay, M.1    Wary, K.K.2    Dans, M.3    Birge, R.B.4    Giancotti, F.G.5
  • 31
    • 84871574859 scopus 로고    scopus 로고
    • Deguelin an Akt inhibitor, down-regulates NF-kappaB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice
    • Kang, H.W.; Kim, J.M.; Cha, M.Y.; Jung, H.C.; Song, I.S.; Kim, J.S. Deguelin, an Akt inhibitor, down-regulates NF-kappaB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice. Dig. Dis. Sci. 2012, 57, 2873-2882.
    • (2012) Dig. Dis. Sci. , vol.57 , pp. 2873-2882
    • Kang, H.W.1    Kim, J.M.2    Cha, M.Y.3    Jung, H.C.4    Song, I.S.5    Kim, J.S.6
  • 32
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li, Q.; Verma, I.M. NF-kappaB regulation in the immune system. Nat. Rev. Immunol. 2002, 2, 725-734.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 33
    • 33846264945 scopus 로고    scopus 로고
    • RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility
    • Chang, Y.W.; Marlin, J.W.; Chance, T.W.; Jakobi, R. RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility. Cancer Res. 2006, 66, 11700-11708.
    • (2006) Cancer Res. , vol.66 , pp. 11700-11708
    • Chang, Y.W.1    Marlin, J.W.2    Chance, T.W.3    Jakobi, R.4
  • 34
    • 1642299123 scopus 로고    scopus 로고
    • Collagen IV regulates Caco-2 migration and ERK activation via alpha1beta1-and alpha2beta1-integrin-dependent Src kinase activation
    • Sanders, M.A.; Basson, M.D. Collagen IV regulates Caco-2 migration and ERK activation via alpha1beta1-and alpha2beta1-integrin-dependent Src kinase activation. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 286, G547-557.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.286 , pp. G547-557
    • Sanders, M.A.1    Basson, M.D.2
  • 35
    • 79959929521 scopus 로고    scopus 로고
    • Molecular targeted therapy of hepatocellular carcinoma-Results of the first clinical studies
    • Wiedmann, M.W.; Mossner, J. Molecular targeted therapy of hepatocellular carcinoma-Results of the first clinical studies. Curr. Cancer Drug Targets 2011, 11, 714-733.
    • (2011) Curr. Cancer Drug Targets , vol.11 , pp. 714-733
    • Wiedmann, M.W.1    Mossner, J.2
  • 36
    • 17844404832 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells
    • Mayoral, R.; Fernandez-Martinez, A.; Bosca, L.; Martin-Sanz, P. Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells. Carcinogenesis 2005, 26, 753-761.
    • (2005) Carcinogenesis , vol.26 , pp. 753-761
    • Mayoral, R.1    Fernandez-Martinez, A.2    Bosca, L.3    Martin-Sanz, P.4
  • 37
    • 84883154324 scopus 로고    scopus 로고
    • Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model
    • Boreddy, S.R.; Srivastava, S.K. Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model. Oncogene 2012, 32, 3980-3991.
    • (2012) Oncogene , vol.32 , pp. 3980-3991
    • Boreddy, S.R.1    Srivastava, S.K.2
  • 38
    • 79960259999 scopus 로고    scopus 로고
    • Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway
    • Chiu, Y.J.; Hour, M.J.; Lu, C.C.; Chung, J.G.; Kuo, S.C.; Huang, W.W.; Chen, H.J.; Jin, Y.A.; Yang, J.S. Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway. J. Orthop. Res. 2011, 29, 1448-1456.
    • (2011) J. Orthop. Res. , vol.29 , pp. 1448-1456
    • Chiu, Y.J.1    Hour, M.J.2    Lu, C.C.3    Chung, J.G.4    Kuo, S.C.5    Huang, W.W.6    Chen, H.J.7    Jin, Y.A.8    Yang, J.S.9
  • 39
    • 78349236990 scopus 로고    scopus 로고
    • Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells
    • Huang, W.W.; Chiu, Y.J.; Fan, M.J.; Lu, H.F.; Yeh, H.F.; Li, K.H.; Chen, P.Y.; Chung, J.G.; Yang, J.S. Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells. Mol. Nutr. Food Res. 2010, 54, 1585-1595.
    • (2010) Mol. Nutr. Food Res. , vol.54 , pp. 1585-1595
    • Huang, W.W.1    Chiu, Y.J.2    Fan, M.J.3    Lu, H.F.4    Yeh, H.F.5    Li, K.H.6    Chen, P.Y.7    Chung, J.G.8    Yang, J.S.9
  • 40
    • 84890565131 scopus 로고    scopus 로고
    • Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways
    • Chueh, F.S.; Chen, Y.Y.; Huang, A.C.; Ho, H.C.; Liao, C.L.; Yang, J.S.; Kuo, C.L.; Chung, J.G. Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways. Environ. Toxicol. 2011, 29, 21-29.
    • (2011) Environ. Toxicol. , vol.29 , pp. 21-29
    • Chueh, F.S.1    Chen, Y.Y.2    Huang, A.C.3    Ho, H.C.4    Liao, C.L.5    Yang, J.S.6    Kuo, C.L.7    Chung, J.G.8
  • 41
    • 79959957480 scopus 로고    scopus 로고
    • The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino)quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor
    • Chen, K.T.; Hour, M.J.; Tsai, S.C.; Chung, J.G.; Kuo, S.C.; Lu, C.C.; Chiu, Y.J.; Chuang, Y.H.; Yang, J.S. The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino)quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor. Int. J. Oncol. 2011, 39, 611-619.
    • (2011) Int. J. Oncol. , vol.39 , pp. 611-619
    • Chen, K.T.1    Hour, M.J.2    Tsai, S.C.3    Chung, J.G.4    Kuo, S.C.5    Lu, C.C.6    Chiu, Y.J.7    Chuang, Y.H.8    Yang, J.S.9
  • 42
    • 77958049067 scopus 로고    scopus 로고
    • Apoptotic action of ursolic acid isolated from Corni fructus in RC-58T/h/SA#4 primary human prostate cancer cells
    • Kwon, S.H.; Park, H.Y.; Kim, J.Y.; Jeong, I.Y.; Lee, M.K.; Seo, K.I. Apoptotic action of ursolic acid isolated from Corni fructus in RC-58T/h/SA#4 primary human prostate cancer cells. Bioorg. Med. Chem. Lett. 2010, 20, 6435-6438.
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 6435-6438
    • Kwon, S.H.1    Park, H.Y.2    Kim, J.Y.3    Jeong, I.Y.4    Lee, M.K.5    Seo, K.I.6
  • 43
    • 73749087888 scopus 로고    scopus 로고
    • Investigation on the morphological protective effect of 5-hydroxymethylfurfural extracted from wine-processed Fructus corni on human L02 hepatocytes
    • Wang, M.Y.; Zhao, F.M.; Peng, H.Y.; Lou, C.H.; Li, Y.; Ding, X.; Yu, X.Y.; Yang, G.M.; Xu, D.Q.; Jiang, L.H.; et al. Investigation on the morphological protective effect of 5-hydroxymethylfurfural extracted from wine-processed Fructus corni on human L02 hepatocytes. J. Ethnopharmacol. 2010, 130, 424-428.
    • (2010) J. Ethnopharmacol. , vol.130 , pp. 424-428
    • Wang, M.Y.1    Zhao, F.M.2    Peng, H.Y.3    Lou, C.H.4    Li, Y.5    Ding, X.6    Yu, X.Y.7    Yang, G.M.8    Xu, D.Q.9    Jiang, L.H.10
  • 44
    • 84862830254 scopus 로고    scopus 로고
    • Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways
    • Liao, C.L.; Lai, K.C.; Huang, A.C.; Yang, J.S.; Lin, J.J.; Wu, S.H.; Gibson Wood, W.; Lin, J.G.; Chung, J.G. Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways. Food Chem. Toxicol. 2012, 50, 1734-1740.
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 1734-1740
    • Liao, C.L.1    Lai, K.C.2    Huang, A.C.3    Yang, J.S.4    Lin, J.J.5    Wu, S.H.6    Gibson Wood, W.7    Lin, J.G.8    Chung, J.G.9
  • 45
    • 0030949650 scopus 로고    scopus 로고
    • The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix
    • Pilcher, B.K.; Dumin, J.A.; Sudbeck, B.D.; Krane, S.M.; Welgus, H.G.; Parks, W.C. The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix. J. Cell Biol. 1997, 137, 1445-1457.
    • (1997) J. Cell Biol. , vol.137 , pp. 1445-1457
    • Pilcher, B.K.1    Dumin, J.A.2    Sudbeck, B.D.3    Krane, S.M.4    Welgus, H.G.5    Parks, W.C.6
  • 46
    • 0035300534 scopus 로고    scopus 로고
    • Lysophosphatidic acid promotes matrix metalloproteinase (MMP) activation and MMP-dependent invasion in ovarian cancer cells
    • Fishman, D.A.; Liu, Y.; Ellerbroek, S.M.; Stack, M.S. Lysophosphatidic acid promotes matrix metalloproteinase (MMP) activation and MMP-dependent invasion in ovarian cancer cells. Cancer Res. 2001, 61, 3194-3199.
    • (2001) Cancer Res. , vol.61 , pp. 3194-3199
    • Fishman, D.A.1    Liu, Y.2    Ellerbroek, S.M.3    Stack, M.S.4
  • 47
    • 0036605041 scopus 로고    scopus 로고
    • Inhibitory effects of a luteinizing hormone-releasing hormone agonist on basal and epidermal growth factor-induced cell proliferation and metastasis-associated properties in human epidermoid carcinoma A431 cells
    • Huang, Y.T.; Hwang, J.J.; Lee, L.T.; Liebow, C.; Lee, P.P.; Ke, F.C.; Lo, T.B.; Schally, A.V.; Lee, M.T. Inhibitory effects of a luteinizing hormone-releasing hormone agonist on basal and epidermal growth factor-induced cell proliferation and metastasis-associated properties in human epidermoid carcinoma A431 cells. Int. J. Cancer 2002, 99, 505-513.
    • (2002) Int. J. Cancer , vol.99 , pp. 505-513
    • Huang, Y.T.1    Hwang, J.J.2    Lee, L.T.3    Liebow, C.4    Lee, P.P.5    Ke, F.C.6    Lo, T.B.7    Schally, A.V.8    Lee, M.T.9
  • 48
    • 34547817207 scopus 로고    scopus 로고
    • Crude extracts of Euchresta formosana radix inhibit invasion and migration of human hepatocellular carcinoma cells
    • Hsu, S.C.; Kuo, C.L.; Lin, J.P.; Lee, J.H.; Lin, C.C.; Su, C.C.; Yang, M.D.; Chung, J.G. Crude extracts of Euchresta formosana radix inhibit invasion and migration of human hepatocellular carcinoma cells. Anticancer Res. 2007, 27, 2377-2384.
    • (2007) Anticancer Res. , vol.27 , pp. 2377-2384
    • Hsu, S.C.1    Kuo, C.L.2    Lin, J.P.3    Lee, J.H.4    Lin, C.C.5    Su, C.C.6    Yang, M.D.7    Chung, J.G.8
  • 49
    • 84872772327 scopus 로고    scopus 로고
    • Deguelin induces both apoptosis and autophagy in cultured head and neck squamous cell carcinoma cells
    • Yang, Y.L.; Ji, C.; Bi, Z.G.; Lu, C.C.; Wang, R.; Gu, B.; Cheng, L. Deguelin induces both apoptosis and autophagy in cultured head and neck squamous cell carcinoma cells. PLoS One 2013, 8, e54736.
    • (2013) PLoS One , vol.8 , pp. e54736
    • Yang, Y.L.1    Ji, C.2    Bi, Z.G.3    Lu, C.C.4    Wang, R.5    Gu, B.6    Cheng, L.7
  • 50
    • 84878878719 scopus 로고    scopus 로고
    • Deguelin action involves c-Met and EGFR signaling pathways in triple negative breast cancer cells
    • Mehta, R.; Katta, H.; Alimirah, F.; Patel, R.; Murillo, G.; Peng, X.; Muzzio, M.; Mehta, R.G. Deguelin action involves c-Met and EGFR signaling pathways in triple negative breast cancer cells. PLoS One 2013, 8, e65113.
    • (2013) PLoS One , vol.8 , pp. e65113
    • Mehta, R.1    Katta, H.2    Alimirah, F.3    Patel, R.4    Murillo, G.5    Peng, X.6    Muzzio, M.7    Mehta, R.G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.