Corrigendum to: EGFR-mediated Akt and MAPKs signal pathways play a crucial role in patulin-induced cell proliferation in primary murine keratinocytes via modulation of Cyclin D1 and COX-2 expression (Molecular Carcinogenesis, (2014), 53, 12, (988-998), 10.1002/mc.22060);EGFR-mediated Akt and MAPKs signal pathways play a crucial role in patulin-induced cell proliferation in primary murine keratinocytes via modulation of Cyclin D1 and COX-2 expression

Molecular Carcinogenesis

Volumn 53, Issue 12, 2014, Pages 988-998

  Alam, Shamshad ^a   Pal, Anu ^a   Kumar, Rahul ^a   Dwivedi, Premendra D ^a   Das, Mukul ^a   Ansari, Kausar M ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Mycotoxin; Patulin; Primary mouse keratinocytes; Proliferation; Signaling pathways

Indexed keywords

CYCLIN D1; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PATULIN; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE B; RAS PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; EGFR PROTEIN, MOUSE; PHOSPHATIDYLINOSITOL 3 KINASE; PTGS2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; COX 2 GENE; CYCLIN D1 GENE; CYTOTOXICITY; ENZYME ACTIVATION; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; KERATINOCYTE; MOUSE; MTT ASSAY; NEWBORN; NF KB GENE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; PROMOTER REGION; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; PHOSPHORYLATION;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; CYCLOOXYGENASE 2; KERATINOCYTES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PATULIN; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 84911444174     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.23115     Document Type: Erratum

References (63)

1. Steiman R, Seigle-Murandi F, Sage L, et al. Production of patulin by micromycetes. Mycopathologia 1989; 105:129-133.
2. Harrison MA. Presence and stability of patulin in apple products: A review. J Food Saf 1989; 9:147-153.
3. Yurdun T, Omurtag GZ, Ersoy O. Incidence of patulin in apple juices marketed in Turkey. J Food Prot 2001; 64:1851-1853.
4. Saxena N, Dwivedi PD, Ansari KM, et al. Incidence of patulin in apple juices and its likely intake in Indian population. Food Addit Contam B 2008; 1:140-146.
5. Gökmen V, Acar J. Incidence of patulin in apple juice concentrates produced in Turkey. J Chromatogr A 1998; 815:99-102.
6. Speijers GJ, Franken MA, Van FX, et al. Subacute toxicity study of patulin in the rat: Effect on the kidney and the gastrointestinal tract. Food Chem Toxicol 1998; 26:23-30.
7. McKinley ER, Carlton WW, Boon GD. Patulin mycotoxicosis in the rat: Toxicology, pathology and clinical pathology. Food Chem Toxicol 1982; 20:289-300.
8. Escoula L, Thomsen M, Bourdiol D, et al. Patulin immunotoxicology: Effect on phagocyte activation and the cellular and humoral immune system of mice and rabbits. Int J Immunopharmacol 1988; 10:983-989.
9. Alves I, Oliveira NG, Laires A, et al. Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells: Role of ascorbic acid as a modulator of patulin clastogenicity. Mutagenesis 2000; 15:229-234.
10. Liu BH, Yu FY, Wu TS, et al. Evaluation of genotoxic risk and oxidative DNA damage in mammalian cells exposed to mycotoxins, patulin and citrinin. Toxicol Appl Pharmacol 2003; 191:255-263.
11. Saxena N, Ansari KM, Kumar R, et al. Patulin causes DNA damage leading to cell cycle arrest and apoptosis through modulation of Bax, p53 and p21/WAF1 proteins in skin of mice. Toxicol Appl Pharmacol 2009; 234:192-201.
12. de Melo FT, de Oliveira IM, Greggio S, et al. DNA damage in organs of mice treated acutely with patulin, a known mycotoxin. Food Chem Toxicol 2012; 50:3548-3555.
13. Glaser N, Stopper H. Patulin: Mechanism of genotoxicity. Food Chem Toxicol 2012; 50:1796-1801.
14. Schumacher DM, Müller C, Metzler M, et al. DNA-DNA cross-links contribute to the mutagenic potential of the mycotoxin patulin. Toxicol Lett 2006; 166:268-275.
15. Arafat W, Musa MN. Patulin-induced inhibition of protein synthesis in hepatoma tissue culture. Res Commun Mol Pathol Pharmacol 1995; 87:177-186.
16. Barhoumi R, Burghardt RC. Kinetic analysis of the chronology of patulin- and gossypol-induced cytotoxicity in vitro. Fundam Appl Toxicol 1996; 30:290-297.
17. Lindroth S, von Wright A. Detoxification of patulin by adducts formation with cysteine. J Environ Pathol Toxicol Oncol 1990; 10:254-259.
18. FAO. Food and Nutrition. Paper 14/10, manual of food quality control 10. Traning in mycotoxin analysis. Food and Agriculture Organization of the United Nations, Rome, 1990, pp. 4-10.
19. WHO. Safety Evaluation of Certain Mycotoxins in Food Prepared by 49th Meeting of JECFA Food Additives Series: 47. Geneva, Switzerland: WHO; 1998.
20. 3H]T-2 toxin in skin. Food Chem Toxicol 1987; 25:379-386.
21. Kemppainen BW, Page JG, Riley RT. Comparison of in vivo and in vitro percutaneous absorption of T-2 toxin in guinea pigs. Toxicon 1987; 25:1153-1162.
22. Peraica M, Radić B, Lucić A, et al. Toxic effects of mycotoxins in humans. Bull WHO 1999; 77:754-766.
23. Boonen J, Malysheva SV, Taevernier L, et al. Human skin penetration of selected model mycotoxins. Toxicology 2012; 301:21-32.
24. Rastogi S, Dogra RKS, Khanna SK, et al. Skin tumorigenic potential of aflatoxin B1 in mice. Food Chem Toxicol 2006; 44:670-677.
25. Saxena N, Ansari KM, Kumar R, et al. Role of mitogen activated protein kinases in skin tumorigenicity of Patulin. Toxicol Appl Pharmacol 2011; 257:264-271.
26. Kumar R, Ansari KM, Chaudhari BP, et al. Topical application of ochratoxin A causes DNA damage and tumor initiation in mouse skin. PLoS ONE 2012; 7:e47280.
27. Kumar R, Das M, Ansari KM. Nexrutine(R) inhibits tumorigenesis in mouse skin and induces apoptotic cell death in human squamous carcinoma A431 and human melanoma A375 cells. Carcinogenesis 2012; 33:1909-1918.
28. Dickens F, Jones HEH. Carcinogenic activity of a series of reactive lactones and realted substances. Br J Cancer 1961; 15:85-100.
29. Osswald H, Frank HK, Komitowski D, et al. Long-term testing of patulin administered orally to Sprague-Dawley rats and Swiss mice. Food Cosmet Toxicol 1978; 16:243-247.
30. Becci PJ, Hess HK, Johnson WD, et al. Parent, long-term carcinogenicity and toxicity studies of Patulin in rat. J Appl Toxicol 1981; 1:256-261.
31. Poirier MC. Chemical-induced DNA damage and human cancer risk. Nat Rev Cancer 2004; 4:630-637.
32. Rundhaug JE, Fischer SM. Molecular mechanisms of mouse skin tumor promotion. Cancers 2010; 2:436-482.
33. Moon Y, Pestka JJ. Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases. Toxicol Sci 2002; 69:373-382.
34. Schramek H, Wilflingseder D, Pollack V, et al. Ochratoxin A-induced stimulation of extracellular signal-regulated kinases 1/2 is associated with Madin-Darby canine kidney-C7 cell dedifferentiation. J Pharmacol Exp Ther 1997; 283:1460-1468.
35. Shifrin VI, Anderson P. Trichothecene mycotoxins trigger a ribotoxic stress response that activates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase and induces apoptosis. J Biol Chem 1999; 274:13985-13992.
36. Wattenberg EV, Badria FA, Shier WT. Activation of mitogen-activated protein kinase by the carcinogenic mycotoxin fumonisin B1. Biochem Biophys Res Commun 1996; 227:622-627.
37. Yuspa SH, Harris CC. Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro. Exp Cell Res 1974; 86:95-105.
38. Ansari KM, Rundhaug JE, Fischer SM. Multiple signaling pathways are responsible for prostaglandin E2-induced murine keratinocyte proliferation. Mol Cancer Res 2008; 6:1003-1016.
39. Chun KS, Keum YS, Han SS, et al. Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-κB activation. Carcinogenesis 2003; 24:1515-1524.
40. Dorsam RT, Gutkind JS. G-protein-coupled receptors and cancer. Nat Rev Cancer 2007; 7:79-94.
41. Budunova IV, Perez P, Vaden VR, et al. Increased expression of p50-NF-κB and constitutive activation of NF-κB transcription factors during mouse skin carcinogenesis. Oncogene 1999; 18:7423-7431.
42. Casanova ML, Larcher F, Casanova B, et al. A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis. Cancer Res 2002; 62:3402-3407.
43. Chen N, Ma WY, She QB, et al. Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction. J Biol Chem 2001; 276:46722-46728.
44. Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature 2001; 410:37-40.
45. Zhang W, Liu HT. MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res 2002; 12:9-18.
46. Bourcier C, Jacquel A, Hess J, et al. p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis. Cancer Res 2006; 66:2700-2707.
47. Engelberg D. Stress-activated protein kinases-tumor suppressors or tumor initiators? Semin Cancer Biol 2004; 14:271-282.
48. Schindler EM, Hindes A, Gribben EL, et al. p38δ mitogen-activated protein kinase is essential for skin tumor development in mice. Cancer Res 2009; 69:4648-4655.
49. Bachelor MA, Bowden GT. UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression. Semin Cancer Biol 2004; 14:131-138.
50. Suzukawa K, Weber TJ, Colburn NH. AP-1, NF-κB, ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model. Environ Health Perspect 2002; 110:865-870.
51. Wu TS, Yu FY, Su CC, et al. Activation of ERK mitogen-activated protein kinase in human cells by the mycotoxin patulin. Toxicol Appl Pharmacol 2005; 207:103-111.
52. Liu BH, Wu TS, Yu FY, et al. Mycotoxin patulin activates the p38 kinase and JNK signaling pathways in human embryonic kidney cells. Toxicol Sci 2006; 89:423-430.
53. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 1995; 270:16483-16486.
54. Bachelor MA, Cooper SJ, Sikorski ET, et al. Inhibition of p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase decreases UVB-induced activator protein-1 and cyclooxygenase-2 in a SKH-1 hairless mouse model. Mol Cancer Res 2005; 3:90-99.
55. Karin M, Liu Z, Zandi E. AP-1 function and regulation. Curr Opin Cell Biol 1997; 9:240-246.
56. Lee JC, Kundu JK, Hwang DM, et al. Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-κB and AP-1: IκB kinase and c-Jun-N-terminal kinase as respective potential upstream targets. Carcinogenesis 2007; 28:1491-1498.
57. Romashkova JA, Makarov SS. NF-κB is a target of AKT in anti-apoptotic PDGF signaling. Nature 1999; 401:86-90.
58. Guttridge DC, Albanese C, Reuther JY, et al. NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol 1999; 19:5785-5799.
59. Tiano HF, Loftin CD, Akunda J, et al. Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis. Cancer Res 2002; 62:3395-3401.
60. Segrelles C, Ruiz S, Perez P, et al. Functional roles of Akt signaling in mouse skin tumorigenesis. Oncogene 2002; 21:53-64.
61. Martinez LA. Deregulated expression of cyclin D1 overrides antimitogenic signals. Oncogene 2000; 19:315-322.
62. Robles AI, Rodriguez-Puebla ML, Glick AB, et al. Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo. Genes Dev 1998; 12:2469-2474.
63. Filmus J, Robles AI, Shi W, et al. Induction of cyclin D1 overexpression by activated ras. Oncogene 1994; 9:3627-3633.