메뉴 건너뛰기




Volumn 63, Issue 1, 2015, Pages 163-176

Blockade of monoacylglycerol lipase inhibits oligodendrocyte excitotoxicity and prevents demyelination in vivo

Author keywords

2 AG; AMPA receptors; CB1< inf> receptors; Multiple sclerosis; Myelin

Indexed keywords

1,3 BENZODIOXOLE DERIVATIVE; 4 [BIS(1,3 BENZODIOXOL 5 YL)HYDROXYMETHYL] 1 PIPERIDINECARBOXYLIC ACID 4 NITROPHENYL ESTER; ACYLGLYCEROL LIPASE; AMIDASE; BENZAMIDE DERIVATIVE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR AFFECTING AGENT; CARBAMIC ACID DERIVATIVE; CYCLOHEXYL CARBAMIC ACID 3'-CARBAMOYLBIPHENYL-3-YL ESTER; FATTY-ACID AMIDE HYDROLASE; PIPERIDINE DERIVATIVE;

EID: 84911403377     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22742     Document Type: Article
Times cited : (76)

References (58)
  • 1
    • 0036194257 scopus 로고    scopus 로고
    • Ca(2+) influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes
    • Alberdi E, Sánchez-Gómez MV, Marino A, Matute C. 2002. Ca(2+) influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes. Neurobiol Dis 9:234-243.
    • (2002) Neurobiol Dis , vol.9 , pp. 234-243
    • Alberdi, E.1    Sánchez-Gómez, M.V.2    Marino, A.3    Matute, C.4
  • 2
    • 84887206057 scopus 로고    scopus 로고
    • Regional regulation of glutamate signaling during cuprizone-induced demyelination in the brain
    • Azami Tameh A, Clarner T, Beyer C, Atlasi MA, Hassanzadeh G, Naderian H. 2013. Regional regulation of glutamate signaling during cuprizone-induced demyelination in the brain. Ann Anat 195:415-423.
    • (2013) Ann Anat , vol.195 , pp. 415-423
    • Azami Tameh, A.1    Clarner, T.2    Beyer, C.3    Atlasi, M.A.4    Hassanzadeh, G.5    Naderian, H.6
  • 5
    • 37149013708 scopus 로고    scopus 로고
    • A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
    • Blankman JL, Simon GM, Cravatt BF. 2007. A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. Chem Biol 14:1347-1356.
    • (2007) Chem Biol , vol.14 , pp. 1347-1356
    • Blankman, J.L.1    Simon, G.M.2    Cravatt, B.F.3
  • 10
    • 0037207088 scopus 로고    scopus 로고
    • A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation
    • Dinh TP, Freund TF, Piomelli D. 2002. A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation. Chem Phys Lipids 121:149-158.
    • (2002) Chem Phys Lipids , vol.121 , pp. 149-158
    • Dinh, T.P.1    Freund, T.F.2    Piomelli, D.3
  • 13
    • 0034671193 scopus 로고    scopus 로고
    • NBQX attenuates excitotoxic injury in developing white matter
    • Follett PL, Rosenberg PA, Volpe JJ, Jensen FE. 2000. NBQX attenuates excitotoxic injury in developing white matter. J Neurosci 20:9235-9241.
    • (2000) J Neurosci , vol.20 , pp. 9235-9241
    • Follett, P.L.1    Rosenberg, P.A.2    Volpe, J.J.3    Jensen, F.E.4
  • 16
    • 84999905115 scopus 로고    scopus 로고
    • Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways
    • Gomez O, Sanchez-Rodriguez A, Le M, Sanchez-Caro C, Molina-Holgado F, Molina-Holgado E. 2011. Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways. Br J Pharmacol 163:1520-1532.
    • (2011) Br J Pharmacol , vol.163 , pp. 1520-1532
    • Gomez, O.1    Sanchez-Rodriguez, A.2    Le, M.3    Sanchez-Caro, C.4    Molina-Holgado, F.5    Molina-Holgado, E.6
  • 17
    • 0031148953 scopus 로고    scopus 로고
    • Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis
    • Hardin-Pouzet H, Krakowski M, Bourbonnière L, Didier-Bazes M, Tran E, Owens T. 1997. Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis. Glia 20:79-85.
    • (1997) Glia , vol.20 , pp. 79-85
    • Hardin-Pouzet, H.1    Krakowski, M.2    Bourbonnière, L.3    Didier-Bazes, M.4    Tran, E.5    Owens, T.6
  • 18
    • 33646817416 scopus 로고    scopus 로고
    • Age increases axon loss associated with primary demyelination in cuprizone-induced demyelination in C57BL/6 mice
    • Irvine KA, Blakemore WF. 2006. Age increases axon loss associated with primary demyelination in cuprizone-induced demyelination in C57BL/6 mice. J Neuroimmunol 175:69-76.
    • (2006) J Neuroimmunol , vol.175 , pp. 69-76
    • Irvine, K.A.1    Blakemore, W.F.2
  • 19
    • 21744455710 scopus 로고    scopus 로고
    • Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation
    • Jackson SJ, Pryce G, Diemel LT, Cuzner ML, Baker D. 2005. Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation. Neuroscience 134:261-268.
    • (2005) Neuroscience , vol.134 , pp. 261-268
    • Jackson, S.J.1    Pryce, G.2    Diemel, L.T.3    Cuzner, M.L.4    Baker, D.5
  • 20
    • 75549089982 scopus 로고    scopus 로고
    • HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage
    • Kim JY, Shen S, Dietz K, He Y, Howell O, Reynolds R, Casaccia P. 2010. HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage. Nat Neurosci 13:180-189.
    • (2010) Nat Neurosci , vol.13 , pp. 180-189
    • Kim, J.Y.1    Shen, S.2    Dietz, K.3    He, Y.4    Howell, O.5    Reynolds, R.6    Casaccia, P.7
  • 21
    • 33751425712 scopus 로고    scopus 로고
    • Cannabinoids and neuronal damage: Differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures
    • Kreutz S, Koch M, Ghadban C, Korf HW, Dehghani F. 2007. Cannabinoids and neuronal damage: Differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. Exp Neurol 203:246-257.
    • (2007) Exp Neurol , vol.203 , pp. 246-257
    • Kreutz, S.1    Koch, M.2    Ghadban, C.3    Korf, H.W.4    Dehghani, F.5
  • 22
    • 61449187249 scopus 로고    scopus 로고
    • Chronic toxic demyelination in the central nervous system leads to axonal damage despite remyelination
    • Lindner M, Fokuhl J, Linsmeier F, Trebst C, Stangel M. 2009. Chronic toxic demyelination in the central nervous system leads to axonal damage despite remyelination. Neurosci Lett 453:120-125.
    • (2009) Neurosci Lett , vol.453 , pp. 120-125
    • Lindner, M.1    Fokuhl, J.2    Linsmeier, F.3    Trebst, C.4    Stangel, M.5
  • 24
    • 69249215137 scopus 로고    scopus 로고
    • Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects
    • Lozovaya N, Min R, Tsintsadze V, Burnashev N. 2009. Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects. Cell Calcium 46:154-162.
    • (2009) Cell Calcium , vol.46 , pp. 154-162
    • Lozovaya, N.1    Min, R.2    Tsintsadze, V.3    Burnashev, N.4
  • 27
    • 65849418702 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor-dependent and -independent inhibition of depolarization-induced calcium influx in oligodendrocytes
    • Mato S, Alberdi E, Ledent C, Watanabe M, Matute C. 2009. CB1 cannabinoid receptor-dependent and -independent inhibition of depolarization-induced calcium influx in oligodendrocytes. Glia 57:295-306.
    • (2009) Glia , vol.57 , pp. 295-306
    • Mato, S.1    Alberdi, E.2    Ledent, C.3    Watanabe, M.4    Matute, C.5
  • 28
    • 84883158864 scopus 로고    scopus 로고
    • Cytosolic zinc accumulation contributes to excitotoxic oligodendroglial death
    • Mato S, Sánchez-Gómez MV, Bernal-Chico A, Matute C. 2013. Cytosolic zinc accumulation contributes to excitotoxic oligodendroglial death. Glia 61:750-764.
    • (2013) Glia , vol.61 , pp. 750-764
    • Mato, S.1    Sánchez-Gómez, M.V.2    Bernal-Chico, A.3    Matute, C.4
  • 31
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • McCarthy KD, de Vellis J. 1980. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85:890-902.
    • (1980) J Cell Biol , vol.85 , pp. 890-902
    • McCarthy, K.D.1    de Vellis, J.2
  • 32
    • 0031952612 scopus 로고    scopus 로고
    • Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity
    • McDonald JW, Althomsons SP, Hyrc KL, Choi DW, Goldberg MP. 1998. Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity. Nat Med 4:291-297.
    • (1998) Nat Med , vol.4 , pp. 291-297
    • McDonald, J.W.1    Althomsons, S.P.2    Hyrc, K.L.3    Choi, D.W.4    Goldberg, M.P.5
  • 35
    • 0037111841 scopus 로고    scopus 로고
    • Cannabinoids promote oligodendrocyte progenitor survival: Involvement of cannabinoid receptors and phosphatidylinositol-3 kinase/Akt signaling
    • Molina-Holgado E, Vela JM, Arévalo-Martín A, Almazán G, Molina-Holgado F, Borrell J, Guaza C. 2002. Cannabinoids promote oligodendrocyte progenitor survival: Involvement of cannabinoid receptors and phosphatidylinositol-3 kinase/Akt signaling. J Neurosci 22:9742-9753.
    • (2002) J Neurosci , vol.22 , pp. 9742-9753
    • Molina-Holgado, E.1    Vela, J.M.2    Arévalo-Martín, A.3    Almazán, G.4    Molina-Holgado, F.5    Borrell, J.6    Guaza, C.7
  • 38
    • 35348907336 scopus 로고    scopus 로고
    • Endocannabinoid signalling triggered by NMDA receptor-mediated calcium entry into rat hippocampal neurons
    • Ohno-Shosaku T, Hashimotodani Y, Ano M, Takeda S, Tsubokawa H, Kano M. 2007. Endocannabinoid signalling triggered by NMDA receptor-mediated calcium entry into rat hippocampal neurons. J Physiol 584:407-418.
    • (2007) J Physiol , vol.584 , pp. 407-418
    • Ohno-Shosaku, T.1    Hashimotodani, Y.2    Ano, M.3    Takeda, S.4    Tsubokawa, H.5    Kano, M.6
  • 43
    • 0033958462 scopus 로고    scopus 로고
    • Glutamate excitotoxicity in a model of multiple sclerosis
    • Pitt D, Werner P, Raine CS. 2000. Glutamate excitotoxicity in a model of multiple sclerosis. Nat Med 6:67-70.
    • (2000) Nat Med , vol.6 , pp. 67-70
    • Pitt, D.1    Werner, P.2    Raine, C.S.3
  • 44
    • 0023100903 scopus 로고
    • Effectiveness of amantadine in reducing relapses in multiple sclerosis
    • Plaut GS. 1987. Effectiveness of amantadine in reducing relapses in multiple sclerosis. J R Soc Med 80:91-93.
    • (1987) J R Soc Med , vol.80 , pp. 91-93
    • Plaut, G.S.1
  • 46
    • 84887606588 scopus 로고    scopus 로고
    • Therapeutic potential of a novel cannabinoid agent CB52 in the mouse model of experimental autoimmune encephalomyelitis
    • Ribeiro R, Yu F, Wen J, Vana A, Zhang Y. 2013. Therapeutic potential of a novel cannabinoid agent CB52 in the mouse model of experimental autoimmune encephalomyelitis. Neuroscience 254:427-442.
    • (2013) Neuroscience , vol.254 , pp. 427-442
    • Ribeiro, R.1    Yu, F.2    Wen, J.3    Vana, A.4    Zhang, Y.5
  • 47
    • 0043025561 scopus 로고    scopus 로고
    • Excitatory amino acids and multiple sclerosis: Evidence from cerebrospinal fluid
    • Sarchielli P, Greco L, Floridi A, Gallai V. 2003. Excitatory amino acids and multiple sclerosis: Evidence from cerebrospinal fluid. Arch Neurol 60:1082-1088.
    • (2003) Arch Neurol , vol.60 , pp. 1082-1088
    • Sarchielli, P.1    Greco, L.2    Floridi, A.3    Gallai, V.4
  • 48
    • 0142244152 scopus 로고    scopus 로고
    • Caspase-dependent and caspase-independent oligodendrocyte death mediated by AMPA and kainate receptors
    • Sánchez-Gómez MV, Alberdi E, Ibarretxe G, Torre I, Matute C. 2003. Caspase-dependent and caspase-independent oligodendrocyte death mediated by AMPA and kainate receptors. J Neurosci 23:9519-9528.
    • (2003) J Neurosci , vol.23 , pp. 9519-9528
    • Sánchez-Gómez, M.V.1    Alberdi, E.2    Ibarretxe, G.3    Torre, I.4    Matute, C.5
  • 49
    • 79951965680 scopus 로고    scopus 로고
    • Bax and calpain mediate excitotoxic oligodendrocyte death induced by activation of both AMPA and kainate receptors
    • Sánchez-Gómez MV, Alberdi E, Pérez-Navarro E, Alberch J, Matute C. 2011. Bax and calpain mediate excitotoxic oligodendrocyte death induced by activation of both AMPA and kainate receptors. J Neurosci 31:2996-3006.
    • (2011) J Neurosci , vol.31 , pp. 2996-3006
    • Sánchez-Gómez, M.V.1    Alberdi, E.2    Pérez-Navarro, E.3    Alberch, J.4    Matute, C.5
  • 51
    • 79959977058 scopus 로고    scopus 로고
    • Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats
    • Sciolino NR, Zhou W, Hohmann AG. 2011. Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats. Pharmacol Res 64:226-234.
    • (2011) Pharmacol Res , vol.64 , pp. 226-234
    • Sciolino, N.R.1    Zhou, W.2    Hohmann, A.G.3
  • 52
    • 80053995816 scopus 로고    scopus 로고
    • De- and remyelination in the CNS white and grey matter induced by cuprizone: The old, the new, and the unexpected
    • Skripuletz T, Gudi V, Hackstette D, Stangel M. 2011. De- and remyelination in the CNS white and grey matter induced by cuprizone: The old, the new, and the unexpected. Histol Histopathol 26:1585-1597.
    • (2011) Histol Histopathol , vol.26 , pp. 1585-1597
    • Skripuletz, T.1    Gudi, V.2    Hackstette, D.3    Stangel, M.4
  • 53
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis ameliorated by AMPA antagonists
    • Smith T, Groom A, Zhu B, Turski L. 2000. Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat Med 6:62-66.
    • (2000) Nat Med , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3    Turski, L.4
  • 54
    • 18744407587 scopus 로고    scopus 로고
    • Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T
    • Srinivasan R, Sailasuta N, Hurd R, Nelson S, Pelletier D. 2005. Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. Brain 128:1016-1025.
    • (2005) Brain , vol.128 , pp. 1016-1025
    • Srinivasan, R.1    Sailasuta, N.2    Hurd, R.3    Nelson, S.4    Pelletier, D.5
  • 55
    • 0031442231 scopus 로고    scopus 로고
    • Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases
    • Stover JF, Lowitzsch K, Kempski OS. 1997. Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases. Neurosci Lett 238:25-28.
    • (1997) Neurosci Lett , vol.238 , pp. 25-28
    • Stover, J.F.1    Lowitzsch, K.2    Kempski, O.S.3
  • 57
    • 0030008498 scopus 로고    scopus 로고
    • Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis
    • Wallström E, Diener P, Ljungdahl A, Khademi M, Nilsson CG, Olsson T. 1996. Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis. J Neurol Sci 137:89-96.
    • (1996) J Neurol Sci , vol.137 , pp. 89-96
    • Wallström, E.1    Diener, P.2    Ljungdahl, A.3    Khademi, M.4    Nilsson, C.G.5    Olsson, T.6
  • 58
    • 0034911054 scopus 로고    scopus 로고
    • Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage
    • Werner P, Pitt D, Raine CS. 2001. Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Ann Neurol 50:169-180.
    • (2001) Ann Neurol , vol.50 , pp. 169-180
    • Werner, P.1    Pitt, D.2    Raine, C.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.