-
1
-
-
80051713783
-
The molecular architecture of HIV
-
Briggs JA, Krausslich HG. 2011. The molecular architecture of HIV. J. Mol. Biol. 410:491-500. http://dx.doi.org/10.1016/j.jmb.2011.04.021.
-
(2011)
J. Mol. Biol
, vol.410
, pp. 491-500
-
-
Briggs, J.A.1
Krausslich, H.G.2
-
4
-
-
61549084714
-
Viral protease inhibitors.
-
Anderson J, Schiffer C, Lee SK, Swanstrom R. 2009. Viral protease inhibitors. Handb. Exp. Pharmacol. 2009(189):85-110. http://dx.doi.org /10.1007/978-3-540-79086-0_4.
-
(2009)
Handb. Exp. Pharmacol.
, vol.2009
, Issue.189
, pp. 85-110
-
-
Anderson, J.1
Schiffer, C.2
Lee, S.K.3
Swanstrom, R.4
-
5
-
-
84868216387
-
Current and novel inhibitors of HIV protease
-
Pokorna J, Machala L, Rezacova P, Konvalinka J. 2009. Current and novel inhibitors of HIV protease. Viruses 1:1209-1239. http://dx.doi.org /10.3390/v1031209.
-
(2009)
Viruses
, vol.1
, pp. 1209-1239
-
-
Pokorna, J.1
Machala, L.2
Rezacova, P.3
Konvalinka, J.4
-
6
-
-
73549092917
-
Fifteen years of HIV protease inhibitors: raising the barrier to resistance
-
Wensing AM, van Maarseveen NM, Nijhuis M. 2010. Fifteen years of HIV protease inhibitors: raising the barrier to resistance. Antiviral Res. 85:59-74. http://dx.doi.org/10.1016/j.antiviral.2009.10.003.
-
(2010)
Antiviral Res
, vol.85
, pp. 59-74
-
-
Wensing, A.M.1
van Maarseveen, N.M.2
Nijhuis, M.3
-
7
-
-
12544255655
-
Three-dimensional structure of HIV-1 virus-like particles by electron cryotomography
-
Benjamin J, Ganser-Pornillos BK, Tivol WF, Sundquist WI, Jensen GJ. 2005. Three-dimensional structure of HIV-1 virus-like particles by electron cryotomography. J. Mol. Biol. 346:577-588. http://dx.doi.org/10 .1016/j.jmb.2004.11.064.
-
(2005)
J. Mol. Biol
, vol.346
, pp. 577-588
-
-
Benjamin, J.1
Ganser-Pornillos, B.K.2
Tivol, W.F.3
Sundquist, W.I.4
Jensen, G.J.5
-
8
-
-
67650482702
-
Structure and assembly of immature HIV
-
Briggs JA, Riches JD, Glass B, Bartonova V, Zanetti G, Krausslich HG. 2009. Structure and assembly of immature HIV. Proc. Natl. Acad. Sci. U. S. A. 106:11090-11095. http://dx.doi.org/10.1073/pnas.0903535106.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A
, vol.106
, pp. 11090-11095
-
-
Briggs, J.A.1
Riches, J.D.2
Glass, B.3
Bartonova, V.4
Zanetti, G.5
Krausslich, H.G.6
-
9
-
-
33644806492
-
The mechanism of HIV-1 core assembly: insights from threedimensional reconstructions of authentic virions
-
Briggs JA, Grunewald K, Glass B, Forster F, Krausslich HG, Fuller SD. 2006. The mechanism of HIV-1 core assembly: insights from threedimensional reconstructions of authentic virions. Structure 14:15-20. http://dx.doi.org/10.1016/j.str.2005.09.010.
-
(2006)
Structure
, vol.14
, pp. 15-20
-
-
Briggs, J.A.1
Grunewald, K.2
Glass, B.3
Forster, F.4
Krausslich, H.G.5
Fuller, S.D.6
-
10
-
-
0037388765
-
Structural organization of authentic, mature HIV-1 virions and cores
-
Briggs JA, Wilk T, Welker R, Krausslich HG, Fuller SD. 2003. Structural organization of authentic, mature HIV-1 virions and cores. EMBO J. 22: 1707-1715. http://dx.doi.org/10.1093/emboj/cdg143.
-
(2003)
EMBO J
, vol.22
, pp. 1707-1715
-
-
Briggs, J.A.1
Wilk, T.2
Welker, R.3
Krausslich, H.G.4
Fuller, S.D.5
-
11
-
-
34247185183
-
Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells
-
Wright ER, Schooler JB, Ding HJ, Kieffer C, Fillmore C, Sundquist WI, Jensen GJ. 2007. Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells. EMBO J. 26:2218- 2226. http://dx.doi.org/10.1038/sj.emboj.7601664.
-
(2007)
EMBO J
, vol.26
, pp. 2218- 2226
-
-
Wright, E.R.1
Schooler, J.B.2
Ding, H.J.3
Kieffer, C.4
Fillmore, C.5
Sundquist, W.I.6
Jensen, G.J.7
-
12
-
-
0032930797
-
Assembly and analysis of conical models for the HIV-1 core
-
Ganser BK, Li S, Klishko VY, Finch JT, Sundquist WI. 1999. Assembly and analysis of conical models for the HIV-1 core. Science 283:80-83. http://dx.doi.org/10.1126/science.283.5398.80.
-
(1999)
Science
, vol.283
, pp. 80-83
-
-
Ganser, B.K.1
Li, S.2
Klishko, V.Y.3
Finch, J.T.4
Sundquist, W.I.5
-
13
-
-
0034699383
-
Image reconstructions of helical assemblies of the HIV-1 CA protein
-
Li S, Hill CP, Sundquist WI, Finch JT. 2000. Image reconstructions of helical assemblies of the HIV-1 CA protein. Nature 407:409-413. http: //dx.doi.org/10.1038/35030177.
-
(2000)
Nature
, vol.407
, pp. 409-413
-
-
Li, S.1
Hill, C.P.2
Sundquist, W.I.3
Finch, J.T.4
-
14
-
-
84863982480
-
Structure of the immature retroviral capsid at 8 A resolution by cryo-electron microscopy
-
Bharat TA, Davey NE, Ulbrich P, Riches JD, de Marco A, Rumlova M, Sachse C, Ruml T, Briggs JA. 2012. Structure of the immature retroviral capsid at 8 A resolution by cryo-electron microscopy. Nature 487:385- 389. http://dx.doi.org/10.1038/nature11169.
-
(2012)
Nature
, vol.487
, pp. 385- 389
-
-
Bharat, T.A.1
Davey, N.E.2
Ulbrich, P.3
Riches, J.D.4
de Marco, A.5
Rumlova, M.6
Sachse, C.7
Ruml, T.8
Briggs, J.A.9
-
15
-
-
3042648569
-
Key interactions in HIV-1 maturation identified by hydrogen- deuterium exchange
-
Lanman J, Lam TT, Emmett MR, Marshall AG, Sakalian M, Prevelige PE, Jr. 2004. Key interactions in HIV-1 maturation identified by hydrogen- deuterium exchange. Nat. Struct. Mol. Biol. 11:676-677. http://dx .doi.org/10.1038/nsmb790.
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 676-677
-
-
Lanman, J.1
Lam, T.T.2
Emmett, M.R.3
Marshall, A.G.4
Sakalian, M.5
Prevelige Jr., P.E.6
-
16
-
-
0026322839
-
Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity
-
Krausslich HG. 1991. Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity. Proc. Natl. Acad. Sci. U. S. A. 88:3213-3217. http://dx.doi.org /10.1073/pnas.88.8.3213.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A
, vol.88
, pp. 3213-3217
-
-
Krausslich, H.G.1
-
17
-
-
0024784403
-
Cleavage of HIV-1 Gag polyprotein synthesized in vitro: sequential cleavage by the viral protease
-
Erickson-Viitanen S, Manfredi J, Viitanen P, Tribe DE, Tritch R, Hutchison CA, III, Loeb DD, Swanstrom R. 1989. Cleavage of HIV-1 Gag polyprotein synthesized in vitro: sequential cleavage by the viral protease. AIDS Res. Human Retroviruses 5:577-591. http://dx.doi.org/10 .1089/aid.1989.5.577.
-
(1989)
AIDS Res. Human Retroviruses
, vol.5
, pp. 577-591
-
-
Erickson-Viitanen, S.1
Manfredi, J.2
Viitanen, P.3
Tribe, D.E.4
Tritch, R.5
Hutchison III, C.A.6
Loeb, D.D.7
Swanstrom, R.8
-
18
-
-
27744572130
-
Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates
-
Pettit SC, Lindquist JN, Kaplan AH, Swanstrom R. 2005. Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates. Retrovirology 2:66. http://dx.doi.org/10.1186/1742-4690-2-66.
-
(2005)
Retrovirology
, vol.2
, pp. 66
-
-
Pettit, S.C.1
Lindquist, J.N.2
Kaplan, A.H.3
Swanstrom, R.4
-
19
-
-
0027971621
-
The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions
-
Pettit SC, Moody MD, Wehbie RS, Kaplan AH, Nantermet PV, Klein CA, Swanstrom R. 1994. The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions. J. Virol. 68:8017-8027.
-
(1994)
J. Virol
, vol.68
, pp. 8017-8027
-
-
Pettit, S.C.1
Moody, M.D.2
Wehbie, R.S.3
Kaplan, A.H.4
Nantermet, P.V.5
Klein, C.A.6
Swanstrom, R.7
-
20
-
-
35348911923
-
Mutational analysis of the C-terminal gag cleavage sites in human immunodeficiency virus type 1
-
Coren LV, Thomas JA, Chertova E, Sowder RC, II, Gagliardi TD, Gorelick RJ, Ott DE. 2007. Mutational analysis of the C-terminal gag cleavage sites in human immunodeficiency virus type 1. J. Virol. 81: 10047-10054. http://dx.doi.org/10.1128/JVI.02496-06.
-
(2007)
J. Virol
, vol.81
, pp. 10047-10054
-
-
Coren, L.V.1
Thomas, J.A.2
Chertova, E.3
Sowder II, R.C.4
Gagliardi, T.D.5
Gorelick, R.J.6
Ott, D.E.7
-
21
-
-
84870664162
-
Role of the SP2 domain and its proteolytic cleavage in HIV-1 structural maturation and infectivity
-
de Marco A, Heuser AM, Glass B, Krausslich HG, Muller B, Briggs JA. 2012. Role of the SP2 domain and its proteolytic cleavage in HIV-1 structural maturation and infectivity. J. Virol. 86:13708-13716. http://dx.doi .org/10.1128/JVI.01704-12.
-
(2012)
J. Virol
, vol.86
, pp. 13708-13716
-
-
de Marco, A.1
Heuser, A.M.2
Glass, B.3
Krausslich, H.G.4
Muller, B.5
Briggs, J.A.6
-
22
-
-
0031925586
-
Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites
-
Wiegers K, Rutter G, Kottler H, Tessmer U, Hohenberg H, Krausslich HG. 1998. Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites. J. Virol. 72:2846-2854.
-
(1998)
J. Virol
, vol.72
, pp. 2846-2854
-
-
Wiegers, K.1
Rutter, G.2
Kottler, H.3
Tessmer, U.4
Hohenberg, H.5
Krausslich, H.G.6
-
23
-
-
84870340629
-
The choreography of HIV-1 proteolytic processing and virion assembly
-
Lee SK, Potempa M, Swanstrom R. 2012. The choreography of HIV-1 proteolytic processing and virion assembly. J. Biol. Chem. 287:40867- 40874. http://dx.doi.org/10.1074/jbc.R112.399444.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 40867- 40874
-
-
Lee, S.K.1
Potempa, M.2
Swanstrom, R.3
-
24
-
-
84873265652
-
Investigation of HIV-1 assembly and release using modern fluorescence imaging techniques
-
Chojnacki J, Muller B. 2013. Investigation of HIV-1 assembly and release using modern fluorescence imaging techniques. Traffic 14:15-24. http: //dx.doi.org/10.1111/tra.12006.
-
(2013)
Traffic
, vol.14
, pp. 15-24
-
-
Chojnacki, J.1
Muller, B.2
-
25
-
-
0034695668
-
Maturation dynamics of a viral capsid: visualization of transitional intermediate states
-
Lata R, Conway JF, Cheng N, Duda RL, Hendrix RW, Wikoff WR, Johnson JE, Tsuruta H, Steven AC. 2000. Maturation dynamics of a viral capsid: visualization of transitional intermediate states. Cell 100:253-263. http://dx.doi.org/10.1016/S0092-8674(00)81563-9.
-
(2000)
Cell
, vol.100
, pp. 253-263
-
-
Lata, R.1
Conway, J.F.2
Cheng, N.3
Duda, R.L.4
Hendrix, R.W.5
Wikoff, W.R.6
Johnson, J.E.7
Tsuruta, H.8
Steven, A.C.9
-
26
-
-
17044440108
-
Virus maturation: dynamics and mechanism of a stabilizing structural transition that leads to infectivity
-
Steven AC, Heymann JB, Cheng N, Trus BL, Conway JF. 2005. Virus maturation: dynamics and mechanism of a stabilizing structural transition that leads to infectivity. Curr. Opin. Struct. Biol. 15:227-236. http: //dx.doi.org/10.1016/j.sbi.2005.03.008.
-
(2005)
Curr. Opin. Struct. Biol
, vol.15
, pp. 227-236
-
-
Steven, A.C.1
Heymann, J.B.2
Cheng, N.3
Trus, B.L.4
Conway, J.F.5
-
27
-
-
0026328223
-
Analysis of temperature-sensitive mutants of the HIV-1 protease
-
Manchester M, Loeb DD, Everitt L, Moody M, Hutchison CA, III, Swanstrom R. 1991. Analysis of temperature-sensitive mutants of the HIV-1 protease. Adv. Exp. Med. Biol. 306:493-497. http://dx.doi.org/10 .1007/978-1-4684-6012-4_63.
-
(1991)
Adv. Exp. Med. Biol
, vol.306
, pp. 493-497
-
-
Manchester, M.1
Loeb, D.D.2
Everitt, L.3
Moody, M.4
Hutchison III, C.A.5
Swanstrom, R.6
-
28
-
-
0028187279
-
Structural and molecular biology of protease function and inhibition. Keystone Symposium. Santa Fe, New Mexico, March 5-12, 1994. Abstracts.
-
Konvalinka J. 1994. Structural and molecular biology of protease function and inhibition. Keystone Symposium. Santa Fe, New Mexico, March 5-12, 1994. Abstracts. J. Cell. Biochem. Suppl. 18D:117-177.
-
(1994)
J. Cell. Biochem. Suppl.
, vol.18 D
, pp. 117-177
-
-
Konvalinka, J.1
-
29
-
-
2942620594
-
Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation
-
Sluis-Cremer N, Arion D, Abram ME, Parniak MA. 2004. Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation. Int. J. Biochem. Cell Biol. 36:1836-1847. http://dx.doi.org/10.1016/j.biocel .2004.02.020.
-
(2004)
Int. J. Biochem. Cell Biol
, vol.36
, pp. 1836-1847
-
-
Sluis-Cremer, N.1
Arion, D.2
Abram, M.E.3
Parniak, M.A.4
-
30
-
-
0023200396
-
Productive, persistent infection of human colorectal cell lines with human immunodeficiency virus
-
Adachi A, Koenig S, Gendelman HE, Daugherty D, Gattoni-Celli S, Fauci AS, Martin MA. 1987. Productive, persistent infection of human colorectal cell lines with human immunodeficiency virus. J. Virol. 61:209- 213.
-
(1987)
J. Virol
, vol.61
, pp. 209- 213
-
-
Adachi, A.1
Koenig, S.2
Gendelman, H.E.3
Daugherty, D.4
Gattoni-Celli, S.5
Fauci, A.S.6
Martin, M.A.7
-
31
-
-
33847267353
-
Double-labeled HIV-1 particles for study of virus-cell interaction
-
Lampe M, Briggs JA, Endress T, Glass B, Riegelsberger S, Krausslich HG, Lamb DC, Brauchle C, Muller B. 2007. Double-labeled HIV-1 particles for study of virus-cell interaction. Virology 360:92-104. http://dx .doi.org/10.1016/j.virol.2006.10.005.
-
(2007)
Virology
, vol.360
, pp. 92-104
-
-
Lampe, M.1
Briggs, J.A.2
Endress, T.3
Glass, B.4
Riegelsberger, S.5
Krausslich, H.G.6
Lamb, D.C.7
Brauchle, C.8
Muller, B.9
-
32
-
-
0033060752
-
Proline residues in human immunodeficiency virus type 1 p6(Gag) exert a cell type-dependent effect on viral replication and virion incorporation of Pol proteins
-
Dettenhofer M, Yu XF. 1999. Proline residues in human immunodeficiency virus type 1 p6(Gag) exert a cell type-dependent effect on viral replication and virion incorporation of Pol proteins. J. Virol. 73:4696- 4704.
-
(1999)
J. Virol
, vol.73
, pp. 4696- 4704
-
-
Dettenhofer, M.1
Yu, X.F.2
-
33
-
-
59749086857
-
A one-step SYBR green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants
-
Pizzato M, Erlwein O, Bonsall D, Kaye S, Muir D, McClure MO. 2009. A one-step SYBR green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants. J. Virol. Methods 156:1-7. http://dx.doi.org/10.1016/j.jviromet.2008.10.012.
-
(2009)
J. Virol. Methods
, vol.156
, pp. 1-7
-
-
Pizzato, M.1
Erlwein, O.2
Bonsall, D.3
Kaye, S.4
Muir, D.5
McClure, M.O.6
-
34
-
-
25644458666
-
Automated electron microscope tomography using robust prediction of specimen movements
-
Mastronarde DN. 2005. Automated electron microscope tomography using robust prediction of specimen movements. J. Struct. Biol. 152:36- 51. http://dx.doi.org/10.1016/j.jsb.2005.07.007.
-
(2005)
J. Struct. Biol
, vol.152
, pp. 36-51
-
-
Mastronarde, D.N.1
-
35
-
-
0029879295
-
Computer visualization of three-dimensional image data using IMOD
-
Kremer JR, Mastronarde DN, McIntosh JR. 1996. Computer visualization of three-dimensional image data using IMOD. J. Struct. Biol. 116:71- 76. http://dx.doi.org/10.1006/jsbi.1996.0013.
-
(1996)
J. Struct. Biol
, vol.116
, pp. 71- 76
-
-
Kremer, J.R.1
Mastronarde, D.N.2
McIntosh, J.R.3
-
36
-
-
37049036372
-
Binding kinetics of darunavir to human immunodeficiency virus type 1 protease explain the potent antiviral activity and high genetic barrier
-
Dierynck I, De Wit M, Gustin E, Keuleers I, Vandersmissen J, Hallenberger S, Hertogs K. 2007. Binding kinetics of darunavir to human immunodeficiency virus type 1 protease explain the potent antiviral activity and high genetic barrier. J. Virol. 81:13845-13851. http://dx.doi.org/10 .1128/JVI.01184-07.
-
(2007)
J. Virol
, vol.81
, pp. 13845-13851
-
-
Dierynck, I.1
De Wit, M.2
Gustin, E.3
Keuleers, I.4
Vandersmissen, J.5
Hallenberger, S.6
Hertogs, K.7
-
37
-
-
0037028049
-
Relationships between structure and interaction kinetics for HIV-1 protease inhibitors
-
Markgren PO, Schaal W, Hamalainen M, Karlen A, Hallberg A, Samuelsson B, Danielson UH. 2002. Relationships between structure and interaction kinetics for HIV-1 protease inhibitors. J. Med. Chem. 45:5430- 5439. http://dx.doi.org/10.1021/jm0208370.
-
(2002)
J. Med. Chem
, vol.45
, pp. 5430- 5439
-
-
Markgren, P.O.1
Schaal, W.2
Hamalainen, M.3
Karlen, A.4
Hallberg, A.5
Samuelsson, B.6
Danielson, U.H.7
-
38
-
-
1642310506
-
Kinetic and thermodynamic characterization of HIV-1 protease inhibitors
-
Shuman CF, Hamalainen MD, Danielson UH. 2004. Kinetic and thermodynamic characterization of HIV-1 protease inhibitors. J. Mol. Recognit. 17:106-119. http://dx.doi.org/10.1002/jmr.655.
-
(2004)
J. Mol. Recognit
, vol.17
, pp. 106-119
-
-
Shuman, C.F.1
Hamalainen, M.D.2
Danielson, U.H.3
-
39
-
-
0024535339
-
Human immunodeficiency virus protease.Bacterial expression and characterization of the purified aspartic protease.
-
Darke PL, Leu CT, Davis LJ, Heimbach JC, Diehl RE, Hill WS, Dixon RA, Sigal IS. 1989. Human immunodeficiency virus protease. Bacterial expression and characterization of the purified aspartic protease. J. Biol. Chem. 264:2307-2312.
-
(1989)
J. Biol. Chem
, vol.264
, pp. 2307-2312
-
-
Darke, P.L.1
Leu, C.T.2
Davis, L.J.3
Heimbach, J.C.4
Diehl, R.E.5
Hill, W.S.6
Dixon, R.A.7
Sigal, I.S.8
-
40
-
-
0026005186
-
Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism.
-
Hyland LJ, Tomaszek TA, Jr, Meek TD. 1991. Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism. Biochemistry 30: 8454-8463.
-
(1991)
Biochemistry
, vol.30
, pp. 8454-8463
-
-
Hyland, L.J.1
Tomaszek Jr., T.A.2
Meek, T.D.3
-
41
-
-
0028070285
-
Substrate-dependent mechanisms in the catalysis of human immunodeficiency virus protease
-
Polgar L, Szeltner Z, Boros I. 1994. Substrate-dependent mechanisms in the catalysis of human immunodeficiency virus protease. Biochemistry 33:9351-9357. http://dx.doi.org/10.1021/bi00197a040.
-
(1994)
Biochemistry
, vol.33
, pp. 9351-9357
-
-
Polgar, L.1
Szeltner, Z.2
Boros, I.3
-
42
-
-
84859762033
-
Context surrounding processing sites is crucial in determining cleavage rate of a subset of processing sites in HIV-1 Gag and Gag-Pro-Pol polyprotein precursors by viral protease
-
Lee SK, Potempa M, Kolli M, Ozen A, Schiffer CA, Swanstrom R. 2012. Context surrounding processing sites is crucial in determining cleavage rate of a subset of processing sites in HIV-1 Gag and Gag-Pro-Pol polyprotein precursors by viral protease. J. Biol. Chem. 287:13279-13290. http://dx.doi.org/10.1074/jbc.M112.339374.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 13279-13290
-
-
Lee, S.K.1
Potempa, M.2
Kolli, M.3
Ozen, A.4
Schiffer, C.A.5
Swanstrom, R.6
-
43
-
-
0028842279
-
Proteolytic processing of particle-associated retroviral polyproteins by homologous and heterologous viral proteinases
-
Konvalinka J, Heuser AM, Hruskova-Heidingsfeldova O, Vogt VM, Sedlacek J, Strop P, Krausslich HG. 1995. Proteolytic processing of particle-associated retroviral polyproteins by homologous and heterologous viral proteinases. Eur. J. Biochem. 228:191-198. http://dx.doi.org/10 .1111/j.1432-1033.1995.tb20249.x.
-
(1995)
Eur. J. Biochem
, vol.228
, pp. 191-198
-
-
Konvalinka, J.1
Heuser, A.M.2
Hruskova-Heidingsfeldova, O.3
Vogt, V.M.4
Sedlacek, J.5
Strop, P.6
Krausslich, H.G.7
-
44
-
-
70350366737
-
HIV-1 Gag processing intermediates trans-dominantly interfere with HIV-1 infectivity
-
Muller B, Anders M, Akiyama H, Welsch S, Glass B, Nikovics K, Clavel F, Tervo HM, Keppler OT, Krausslich HG. 2009. HIV-1 Gag processing intermediates trans-dominantly interfere with HIV-1 infectivity. J. Biol. Chem. 284:29692-29703. http://dx.doi.org/10.1074/jbc.M109.027144.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 29692-29703
-
-
Muller, B.1
Anders, M.2
Akiyama, H.3
Welsch, S.4
Glass, B.5
Nikovics, K.6
Clavel, F.7
Tervo, H.M.8
Keppler, O.T.9
Krausslich, H.G.10
-
45
-
-
80053436942
-
The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse
-
Jolly C, Welsch S, Michor S, Sattentau QJ. 2011. The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse. PLoS Pathog. 7:e1002226. http://dx.doi.org/10.1371/journal.ppat.1002226.
-
(2011)
PLoS Pathog
, vol.7
-
-
Jolly, C.1
Welsch, S.2
Michor, S.3
Sattentau, Q.J.4
-
46
-
-
77949412821
-
Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition
-
Martin N, Welsch S, Jolly C, Briggs JA, Vaux D, Sattentau QJ. 2010. Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition. J. Virol. 84:3516- 3527. http://dx.doi.org/10.1128/JVI.02651-09.
-
(2010)
J. Virol
, vol.84
, pp. 3516-3527
-
-
Martin, N.1
Welsch, S.2
Jolly, C.3
Briggs, J.A.4
Vaux, D.5
Sattentau, Q.J.6
-
47
-
-
84879534949
-
Gag-Pol processing during HIV-1 virion maturation: a systems biology approach
-
Konnyu B, Sadiq SK, Turanyi T, Hirmondo R, Muller B, Krausslich HG, Coveney PV, Muller V. 2013. Gag-Pol processing during HIV-1 virion maturation: a systems biology approach. PLoS Comput. Biol. 9:e1003103. http://dx.doi.org/10.1371/journal.pcbi.1003103.
-
(2013)
PLoS Comput. Biol
, vol.9
-
-
Konnyu, B.1
Sadiq, S.K.2
Turanyi, T.3
Hirmondo, R.4
Muller, B.5
Krausslich, H.G.6
Coveney, P.V.7
Muller, V.8
-
48
-
-
83655190761
-
Cell-to-cell transfer of HIV-1 via virological synapses leads to endosomal virion maturation that activates viral membrane fusion
-
Dale BM, McNerney GP, Thompson DL, Hubner W, de Los Reyes K, Chuang FY, Huser T, Chen BK. 2011. Cell-to-cell transfer of HIV-1 via virological synapses leads to endosomal virion maturation that activates viral membrane fusion. Cell Host Microbe 10:551-562. http://dx.doi.org /10.1016/j.chom.2011.10.015.
-
(2011)
Cell Host Microbe
, vol.10
, pp. 551-562
-
-
Dale, B.M.1
McNerney, G.P.2
Thompson, D.L.3
Hubner, W.4
de Los Reyes, K.5
Chuang, F.Y.6
Huser, T.7
Chen, B.K.8
-
49
-
-
33846702679
-
A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism
-
Nijhuis M, van Maarseveen NM, Lastere S, Schipper P, Coakley E, Glass B, Rovenska M, de Jong D, Chappey C, Goedegebuure IW, Heilek- Snyder G, Dulude D, Cammack N, Brakier-Gingras L, Konvalinka J, Parkin N, Krausslich HG, Brun-Vezinet F, Boucher CA. 2007. A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism. PLoS Med. 4:e36. http://dx.doi.org/10.1371/journal.pmed.0040036.
-
(2007)
PLoS Med
, vol.4
-
-
Nijhuis, M.1
van Maarseveen, N.M.2
Lastere, S.3
Schipper, P.4
Coakley, E.5
Glass, B.6
Rovenska, M.7
de Jong, D.8
Chappey, C.9
Goedegebuure, I.W.10
Heilek-Snyder, G.11
Dulude, D.12
Cammack, N.13
Brakier-Gingras, L.14
Konvalinka, J.15
Parkin, N.16
Krausslich, H.G.17
Brun-Vezinet, F.18
Boucher, C.A.19
-
50
-
-
69249216636
-
A strongly transdominant mutation in the human immunodeficiency virus type 1 gag gene defines an Achilles heel in the virus life cycle
-
Lee SK, Harris J, Swanstrom R. 2009. A strongly transdominant mutation in the human immunodeficiency virus type 1 gag gene defines an Achilles heel in the virus life cycle. J. Virol. 83:8536-8543. http://dx.doi .org/10.1128/JVI.00317-09.
-
(2009)
J. Virol
, vol.83
, pp. 8536-8543
-
-
Lee, S.K.1
Harris, J.2
Swanstrom, R.3
-
51
-
-
0028915128
-
Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication
-
Engelman A, Englund G, Orenstein JM, Martin MA, Craigie R. 1995. Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication. J. Virol. 69:2729-2736.
-
(1995)
J. Virol
, vol.69
, pp. 2729-2736
-
-
Engelman, A.1
Englund, G.2
Orenstein, J.M.3
Martin, M.A.4
Craigie, R.5
-
52
-
-
0032617446
-
In vivo analysis of retroviral integrase structure and function
-
Engelman A. 1999. In vivo analysis of retroviral integrase structure and function. Adv. Virus Res. 52:411-426. http://dx.doi.org/10.1016/S0065 -3527(08)60309-7.
-
(1999)
Adv. Virus Res
, vol.52
, pp. 411-426
-
-
Engelman, A.1
-
53
-
-
84878137599
-
Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation
-
Jurado KA, Wang H, Slaughter A, Feng L, Kessl JJ, Koh Y, Wang W, Ballandras-Colas A, Patel PA, Fuchs JR, Kvaratskhelia M, Engelman A. 2013. Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation. Proc. Natl. Acad. Sci. U. S. A. 110:8690-8695. http://dx.doi.org/10.1073/pnas.1300703110.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A
, vol.110
, pp. 8690-8695
-
-
Jurado, K.A.1
Wang, H.2
Slaughter, A.3
Feng, L.4
Kessl, J.J.5
Koh, Y.6
Wang, W.7
Ballandras-Colas, A.8
Patel, P.A.9
Fuchs, J.R.10
Kvaratskhelia, M.11
Engelman, A.12
-
54
-
-
84883649897
-
Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells
-
Balakrishnan M, Yant SR, Tsai L, O'Sullivan C, Bam RA, Tsai A, Niedziela-Majka A, Stray KM, Sakowicz R, Cihlar T. 2013. Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells. PLoS One 8:e74163. http://dx.doi .org/10.1371/journal.pone.0074163.
-
(2013)
PLoS One
, vol.8
-
-
Balakrishnan, M.1
Yant, S.R.2
Tsai, L.3
O'Sullivan, C.4
Bam, R.A.5
Tsai, A.6
Niedziela-Majka, A.7
Stray, K.M.8
Sakowicz, R.9
Cihlar, T.10
-
55
-
-
84878214842
-
LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
-
Desimmie BA, Schrijvers R, Demeulemeester J, Borrenberghs D, Weydert C, Thys W, Vets S, Van Remoortel B, Hofkens J, De Rijck J, Hendrix J, Bannert N, Gijsbers R, Christ F, Debyser Z. 2013. LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions. Retrovirology 10:57. http://dx.doi.org/10.1186/1742 -4690-10-57.
-
(2013)
Retrovirology
, vol.10
, pp. 57
-
-
Desimmie, B.A.1
Schrijvers, R.2
Demeulemeester, J.3
Borrenberghs, D.4
Weydert, C.5
Thys, W.6
Vets, S.7
Van Remoortel, B.8
Hofkens, J.9
De Rijck, J.10
Hendrix, J.11
Bannert, N.12
Gijsbers, R.13
Christ, F.14
Debyser, Z.15
-
56
-
-
84895852851
-
Multimodal mechanism of action of allosteric HIV-1 integrase inhibitors
-
Jurado KA, Engelman A. 2013. Multimodal mechanism of action of allosteric HIV-1 integrase inhibitors. Exp. Rev. Mol. Med. 15:e14. http: //dx.doi.org/10.1017/erm.2013.15.
-
(2013)
Exp. Rev. Mol. Med
, vol.15
-
-
Jurado, K.A.1
Engelman, A.2
-
57
-
-
24644493205
-
Virion instability of human immunodeficiency virus type 1 reverse transcriptase (RT) mutated in the protease cleavage site between RT p51 and the RT RNase H domain
-
Abram ME, Parniak MA. 2005. Virion instability of human immunodeficiency virus type 1 reverse transcriptase (RT) mutated in the protease cleavage site between RT p51 and the RT RNase H domain. J. Virol. 79: 11952-11961. http://dx.doi.org/10.1128/JVI.79.18.11952-11961.2005.
-
(2005)
J. Virol
, vol.79
, pp. 11952-11961
-
-
Abram, M.E.1
Parniak, M.A.2
-
58
-
-
70450193040
-
Mutations in the thumb allow human immunodeficiency virus type 1 reverse transcriptase to be cleaved by protease in virions
-
Dunn LL, McWilliams MJ, Das K, Arnold E, Hughes SH. 2009. Mutations in the thumb allow human immunodeficiency virus type 1 reverse transcriptase to be cleaved by protease in virions. J. Virol. 83:12336- 12344. http://dx.doi.org/10.1128/JVI.00676-09.
-
(2009)
J. Virol
, vol.83
, pp. 12336-12344
-
-
Dunn, L.L.1
McWilliams, M.J.2
Das, K.3
Arnold, E.4
Hughes, S.H.5
-
59
-
-
0025297454
-
Dimerization of human immunodeficiency virus type 1 reverse transcriptase. A target for chemotherapeutic intervention.
-
Restle T, Muller B, Goody RS. 1990. Dimerization of human immunodeficiency virus type 1 reverse transcriptase. A target for chemotherapeutic intervention. J. Biol. Chem. 265:8986-8988.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 8986-8988
-
-
Restle, T.1
Muller, B.2
Goody, R.S.3
|