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Volumn 2014, Issue , 2014, Pages

Targets and candidate agents for Type 2 diabetes treatment with computational bioinformatics approach

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; COMPLEMENT; ICOSANOID; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 7; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN; SELENIUM; TRANSCRIPTION FACTOR; BENZOPHENANTHRIDINE DERIVATIVE; ISOQUINOLINE DERIVATIVE; SANGUINARINE; THIORPHAN;

EID: 84911166972     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2014/763936     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 64649104158 scopus 로고    scopus 로고
    • From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
    • 2-s2.0-64649104158
    • Defronzo R. A., From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes 2009 58 4 773 795 10.2337/db09-9028 2-s2.0-64649104158
    • (2009) Diabetes , vol.58 , Issue.4 , pp. 773-795
    • Defronzo, R.A.1
  • 2
    • 0033578476 scopus 로고    scopus 로고
    • Pharmacologic therapy for type 2 diabetes mellitus
    • 2-s2.0-0033578476
    • DeFronzo R. A., Pharmacologic therapy for type 2 diabetes mellitus. Annals of Internal Medicine 1999 131 4 281 303 10.7326/0003-4819-131-4-199908170-00008 2-s2.0-0033578476
    • (1999) Annals of Internal Medicine , vol.131 , Issue.4 , pp. 281-303
    • Defronzo, R.A.1
  • 5
    • 0023221765 scopus 로고
    • Primary prevention of diabetes mellitus
    • 2-s2.0-0023221765
    • Tuomilehto J., Wolf E., Primary prevention of diabetes mellitus. Diabetes Care 1987 10 2 238 248 10.2337/diacare.10.2.238 2-s2.0-0023221765
    • (1987) Diabetes Care , vol.10 , Issue.2 , pp. 238-248
    • Tuomilehto, J.1    Wolf, E.2
  • 6
    • 0026969347 scopus 로고
    • Genetic and environmental determinants of non-insulin-dependent diabetes mellitus (NIDDM)
    • 2-s2.0-0026969347
    • Hamman R. F., Genetic and environmental determinants of non-insulin-dependent diabetes mellitus (NIDDM). Diabetes/Metabolism Reviews 1992 8 4 287 338 10.1002/dmr.5610080402 2-s2.0-0026969347
    • (1992) Diabetes/Metabolism Reviews , vol.8 , Issue.4 , pp. 287-338
    • Hamman, R.F.1
  • 9
    • 17044386953 scopus 로고    scopus 로고
    • Type 2 diabetes: Principles of pathogenesis and therapy
    • 2-s2.0-17044386953
    • Stumvoll M., Goldstein B. J., van Haeften T. W., Type 2 diabetes: principles of pathogenesis and therapy. The Lancet 2005 365 9467 1333 1346 10.1016/S0140-6736(05)61032-X 2-s2.0-17044386953
    • (2005) The Lancet , vol.365 , Issue.9467 , pp. 1333-1346
    • Stumvoll, M.1    Goldstein, B.J.2    Van Haeften, T.W.3
  • 10
    • 0037219411 scopus 로고    scopus 로고
    • β -cell deficit and increased β -cell apoptosis in humans with type 2 diabetes
    • 2-s2.0-0037219411
    • Butler A. E., Janson J., Bonner-Weir S., Ritzel R., Rizza R. A., Butler P. C., β -cell deficit and increased β -cell apoptosis in humans with type 2 diabetes. Diabetes 2003 52 1 102 110 10.2337/diabetes.52.1.102 2-s2.0-0037219411
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5    Butler, P.C.6
  • 11
    • 84890494543 scopus 로고    scopus 로고
    • Role of reduced β -cell mass versus impaired β -cell function in the pathogenesis of type 2 diabetes
    • 2-s2.0-84890494543
    • Meier J. J., Bonadonna R. C., Role of reduced β -cell mass versus impaired β -cell function in the pathogenesis of type 2 diabetes. Diabetes Care 2013 36 2 S113 S119 10.2337/dcS13-2008 2-s2.0-84890494543
    • (2013) Diabetes Care , vol.36 , Issue.2 , pp. S113-S119
    • Meier, J.J.1    Bonadonna, R.C.2
  • 12
    • 34547871639 scopus 로고    scopus 로고
    • GEOquery: A bridge between the Gene Expression Omnibus (GEO) and BioConductor
    • 2-s2.0-34547871639
    • Sean D., Meltzer P. S., GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor. Bioinformatics 2007 23 14 1846 1847 10.1093/bioinformatics/btm254 2-s2.0-34547871639
    • (2007) Bioinformatics , vol.23 , Issue.14 , pp. 1846-1847
    • Sean, D.1    Meltzer, P.S.2
  • 13
    • 33750616076 scopus 로고    scopus 로고
    • Microarray analysis after RNA amplification can detect pronounced differences in gene expression using limma
    • 2-s2.0-33750616076
    • Diboun I., Wernisch L., Orengo C. A., Koltzenburg M., Microarray analysis after RNA amplification can detect pronounced differences in gene expression using limma. BMC Genomics 2006 7, article 252 10.1186/1471-2164-7-252 2-s2.0-33750616076
    • (2006) BMC Genomics , vol.7252
    • Diboun, I.1    Wernisch, L.2    Orengo, C.A.3    Koltzenburg, M.4
  • 14
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
    • article 3 MR2101454
    • Smyth G. K., Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Statistical Applications in Genetics and Molecular Biology 2004 3 article 3 10.2202/1544-6115.1027 MR2101454
    • (2004) Statistical Applications in Genetics and Molecular Biology , vol.3
    • Smyth, G.K.1
  • 15
    • 28444445926 scopus 로고    scopus 로고
    • Vienna, Austria R Foundation for Statistical Computing
    • Team R. D. C., R: A Language and Environment for Statistical Computing 2005 Vienna, Austria R Foundation for Statistical Computing. http://www.R-project.org
    • (2005) R: A Language and Environment for Statistical Computing
  • 16
    • 0033472709 scopus 로고    scopus 로고
    • Resampling-based false discovery rate controlling multiple test procedures for correlated test statistics
    • 2-s2.0-0033472709
    • Yekutieli D., Benjamini Y., Resampling-based false discovery rate controlling multiple test procedures for correlated test statistics. Journal of Statistical Planning and Inference 1999 82 1-2 171 196 10.1016/S0378-3758(99)00041-5 MR1736442 2-s2.0-0033472709
    • (1999) Journal of Statistical Planning and Inference , vol.82 , Issue.1-2 , pp. 171-196
    • Yekutieli, D.1    Benjamini, Y.2
  • 18
    • 79959271429 scopus 로고    scopus 로고
    • WebGestalt2: An updated and expanded version of the Web-based Gene Set Analysis Toolkit
    • supplement 4
    • Duncan D., Prodduturi N., Zhang B., WebGestalt2: an updated and expanded version of the Web-based Gene Set Analysis Toolkit. BMC Bioinformatics 2010 11 supplement 4 P10 10.1186/1471-2105-11-S4-P10
    • (2010) BMC Bioinformatics , vol.11 , pp. P10
    • Duncan, D.1    Prodduturi, N.2    Zhang, B.3
  • 21
    • 52949153587 scopus 로고    scopus 로고
    • Arachidonic-acid-derived eicosanoids: Roles in biology and immunopathology
    • 2-s2.0-52949153587
    • Harizi H., Corcuff J.-B., Gualde N., Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology. Trends in Molecular Medicine 2008 14 10 461 469 10.1016/j.molmed.2008.08.005 2-s2.0-52949153587
    • (2008) Trends in Molecular Medicine , vol.14 , Issue.10 , pp. 461-469
    • Harizi, H.1    Corcuff, J.-B.2    Gualde, N.3
  • 22
    • 0021022903 scopus 로고
    • Arachidonate metabolism in vascular disorders
    • 2-s2.0-0021022903
    • Majerus P. W., Arachidonate metabolism in vascular disorders. The Journal of Clinical Investigation 1983 72 5 1521 1525 10.1172/JCI111110 2-s2.0-0021022903
    • (1983) The Journal of Clinical Investigation , vol.72 , Issue.5 , pp. 1521-1525
    • Majerus, P.W.1
  • 23
    • 0142195896 scopus 로고    scopus 로고
    • Aspirin insensitive eicosanoid biosynthesis in cardiovascular disease
    • 2-s2.0-0142195896
    • Patrignani P., Aspirin insensitive eicosanoid biosynthesis in cardiovascular disease. Thrombosis Research 2003 110 5-6 281 286 10.1016/S0049-3848(03)00382-7 2-s2.0-0142195896
    • (2003) Thrombosis Research , vol.110 , Issue.5-6 , pp. 281-286
    • Patrignani, P.1
  • 24
    • 0024994816 scopus 로고
    • Role of eicosanoids as mediators of inflammation in inflammatory bowel disease
    • 2-s2.0-0024994816
    • Stenson W. F., Role of eicosanoids as mediators of inflammation in inflammatory bowel disease. Scandinavian Journal of Gastroenterology, Supplement 1990 25 172 13 18 2-s2.0-0024994816
    • (1990) Scandinavian Journal of Gastroenterology, Supplement , vol.25 , Issue.172 , pp. 13-18
    • Stenson, W.F.1
  • 25
    • 0022903351 scopus 로고
    • Eicosanoids and their role in the pathogenesis of diarrhoeal diseases
    • 2-s2.0-0022903351
    • Rask-Madsen J., Eicosanoids and their role in the pathogenesis of diarrhoeal diseases. Clinics in Gastroenterology 1986 15 3 545 566 2-s2.0-0022903351
    • (1986) Clinics in Gastroenterology , vol.15 , Issue.3 , pp. 545-566
    • Rask-Madsen, J.1
  • 26
    • 0035433149 scopus 로고    scopus 로고
    • Platelet dysfunction in type 2 diabetes
    • 2-s2.0-0035433149
    • Vinik A. I., Erbas T., Sun Park T., Nolan R., Pittenger G. L., Platelet dysfunction in type 2 diabetes. Diabetes Care 2001 24 8 1476 1485 10.2337/diacare.24.8.1476 2-s2.0-0035433149
    • (2001) Diabetes Care , vol.24 , Issue.8 , pp. 1476-1485
    • Vinik, A.I.1    Erbas, T.2    Sun Park, T.3    Nolan, R.4    Pittenger, G.L.5
  • 27
    • 0020040981 scopus 로고
    • Eicosanoids: Prostaglandins, thromboxanes, leukotrienes, and other derivatives of carbon-20 unsaturated fatty acids
    • 2-s2.0-0020040981
    • Wolfe L. S., Eicosanoids: prostaglandins, thromboxanes, leukotrienes, and other derivatives of carbon-20 unsaturated fatty acids. Journal of Neurochemistry 1982 38 1 1 14 10.1111/j.1471-4159.1982.tb10847.x 2-s2.0-0020040981
    • (1982) Journal of Neurochemistry , vol.38 , Issue.1 , pp. 1-14
    • Wolfe, L.S.1
  • 28
    • 0033579331 scopus 로고    scopus 로고
    • Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes
    • 2-s2.0-0033579331
    • Okumura M., Imanishi M., Yamashita T., Yamamura Y., Kim S., Iwao H., Tanaka S., Fujii S., Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes. Life Sciences 1999 66 5 371 377 10.1016/S0024-3205(99)00603-7 2-s2.0-0033579331
    • (1999) Life Sciences , vol.66 , Issue.5 , pp. 371-377
    • Okumura, M.1    Imanishi, M.2    Yamashita, T.3    Yamamura, Y.4    Kim, S.5    Iwao, H.6    Tanaka, S.7    Fujii, S.8
  • 29
    • 84878231693 scopus 로고    scopus 로고
    • Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion
    • 2-s2.0-84878231693
    • Kimple M. E., Keller M. P., Rabaglia M. R., Pasker R. L., Neuman J. C., Truchan N. A., Brar H. K., Attie A. D., Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion. Diabetes 2013 62 6 1904 1912 10.2337/db12-0769 2-s2.0-84878231693
    • (2013) Diabetes , vol.62 , Issue.6 , pp. 1904-1912
    • Kimple, M.E.1    Keller, M.P.2    Rabaglia, M.R.3    Pasker, R.L.4    Neuman, J.C.5    Truchan, N.A.6    Brar, H.K.7    Attie, A.D.8
  • 30
    • 0035153291 scopus 로고    scopus 로고
    • Latent TGF- β binding protein LTBP-1 contains three potential extracellular matrix interacting domains
    • 2-s2.0-0035153291
    • Unsöld C., Hyytiäinen M., Bruckner-Tuderman L., Keski-Oja J., Latent TGF- β binding protein LTBP-1 contains three potential extracellular matrix interacting domains. Journal of Cell Science 2001 114 1 187 197 2-s2.0-0035153291
    • (2001) Journal of Cell Science , vol.114 , Issue.1 , pp. 187-197
    • Unsöld, C.1    Hyytiäinen, M.2    Bruckner-Tuderman, L.3    Keski-Oja, J.4
  • 31
    • 43049146157 scopus 로고    scopus 로고
    • The role of proteases in transforming growth factor- β activation
    • 2-s2.0-43049146157
    • Jenkins G., The role of proteases in transforming growth factor- β activation. International Journal of Biochemistry and Cell Biology 2008 40 6-7 1068 1078 10.1016/j.biocel.2007.11.026 2-s2.0-43049146157
    • (2008) International Journal of Biochemistry and Cell Biology , vol.40 , Issue.6-7 , pp. 1068-1078
    • Jenkins, G.1
  • 32
    • 82255185487 scopus 로고    scopus 로고
    • L-carnosine inhibits high-glucose-mediated matrix accumulation in human mesangial cells by interfering with TGF- β production and signalling
    • 2-s2.0-82255185487
    • Köppel H., Riedl E., Braunagel M., Sauerhoefer S., Ehnert S., Godoy P., Sternik P., Dooley S., Yard B. A., L-carnosine inhibits high-glucose-mediated matrix accumulation in human mesangial cells by interfering with TGF- β production and signalling. Nephrology Dialysis Transplantation 2011 26 12 3852 3858 10.1093/ndt/gfr324 2-s2.0-82255185487
    • (2011) Nephrology Dialysis Transplantation , vol.26 , Issue.12 , pp. 3852-3858
    • Köppel, H.1    Riedl, E.2    Braunagel, M.3    Sauerhoefer, S.4    Ehnert, S.5    Godoy, P.6    Sternik, P.7    Dooley, S.8    Yard, B.A.9
  • 33
    • 84883175084 scopus 로고    scopus 로고
    • Anti-diabetic treatment regulates pro-fibrotic TGF- β serum levels in type 2 diabetics
    • 2-s2.0-84883175084
    • Pscherer S., Freude T., Forst T., Nussler A. K., Braun K. F., Ehnert S., Anti-diabetic treatment regulates pro-fibrotic TGF- β serum levels in type 2 diabetics. Diabetology and Metabolic Syndrome 2013 5 1, article 48 10.1186/1758-5996-5-48 2-s2.0-84883175084
    • (2013) Diabetology and Metabolic Syndrome , vol.5 , Issue.1
    • Pscherer, S.1    Freude, T.2    Forst, T.3    Nussler, A.K.4    Braun, K.F.5    Ehnert, S.6
  • 35
    • 84860584838 scopus 로고    scopus 로고
    • β -cell-specific gene repression: A mechanism to protect against inappropriate or maladjusted insulin secretion?
    • 2-s2.0-84860584838
    • Schuit F., van Lommel L., Granvik M., Goyvaerts L., de Faudeur G., Schraenen A., Lemaire K., β -cell-specific gene repression: a mechanism to protect against inappropriate or maladjusted insulin secretion? Diabetes 2012 61 5 969 975 10.2337/db11-1564 2-s2.0-84860584838
    • (2012) Diabetes , vol.61 , Issue.5 , pp. 969-975
    • Schuit, F.1    Van Lommel, L.2    Granvik, M.3    Goyvaerts, L.4    De Faudeur, G.5    Schraenen, A.6    Lemaire, K.7
  • 36
    • 0026537450 scopus 로고
    • Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors
    • 2-s2.0-0026537450
    • Hu P., Margolis B., Skolnik E. Y., Lammers R., Ullrich A., Schlessinger J., Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors. Molecular and Cellular Biology 1992 12 3 981 990 2-s2.0-0026537450
    • (1992) Molecular and Cellular Biology , vol.12 , Issue.3 , pp. 981-990
    • Hu, P.1    Margolis, B.2    Skolnik, E.Y.3    Lammers, R.4    Ullrich, A.5    Schlessinger, J.6
  • 38
    • 26844576371 scopus 로고    scopus 로고
    • Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules
    • 2-s2.0-26844576371
    • Zhang Y., Wolf-Yadlin A., Ross P. L., Pappin D. J., Rush J., Lauffenburger D. A., White F. M., Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. Molecular and Cellular Proteomics 2005 4 9 1240 1250 10.1074/mcp.M500089-MCP200 2-s2.0-26844576371
    • (2005) Molecular and Cellular Proteomics , vol.4 , Issue.9 , pp. 1240-1250
    • Zhang, Y.1    Wolf-Yadlin, A.2    Ross, P.L.3    Pappin, D.J.4    Rush, J.5    Lauffenburger, D.A.6    White, F.M.7
  • 39
    • 84902505683 scopus 로고    scopus 로고
    • Sanguinarine is a novel VEGF inhibitor involved in the suppression of angiogenesis and cell migration
    • Xu J.-Y., Meng Q.-H., Chong Y., Sanguinarine is a novel VEGF inhibitor involved in the suppression of angiogenesis and cell migration. Molecular and Clinical Oncology 2013 1 2 331 336
    • (2013) Molecular and Clinical Oncology , vol.1 , Issue.2 , pp. 331-336
    • Xu, J.-Y.1    Meng, Q.-H.2    Chong, Y.3
  • 41
    • 75149114612 scopus 로고    scopus 로고
    • Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3
    • 2-s2.0-75149114612
    • Choi W. Y., Jin C.-Y., Han M. H., Kim G.-Y., Kim N. D., Lee W. H., Kim S.-K., Choi Y. H., Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3. Anticancer Research 2009 29 11 4457 4465 2-s2.0-75149114612
    • (2009) Anticancer Research , vol.29 , Issue.11 , pp. 4457-4465
    • Choi, W.Y.1    Jin, C.-Y.2    Han, M.H.3    Kim, G.-Y.4    Kim, N.D.5    Lee, W.H.6    Kim, S.-K.7    Choi, Y.H.8
  • 43
  • 44
    • 80051655844 scopus 로고    scopus 로고
    • Evaluation of anticancer activities of benzo[c]phenanthridine alkaloid sanguinarine in oral squamous cell carcinoma cell line
    • 2-s2.0-80051655844
    • Tsukamoto H., Kondo S., Mukudai Y., Nagumo T., Yasuda A., Kurihara Y., Kamatani T., Shintani S., Evaluation of anticancer activities of benzo[c]phenanthridine alkaloid sanguinarine in oral squamous cell carcinoma cell line. Anticancer Research 2011 31 9 2841 2846 2-s2.0-80051655844
    • (2011) Anticancer Research , vol.31 , Issue.9 , pp. 2841-2846
    • Tsukamoto, H.1    Kondo, S.2    Mukudai, Y.3    Nagumo, T.4    Yasuda, A.5    Kurihara, Y.6    Kamatani, T.7    Shintani, S.8
  • 45
    • 59449083445 scopus 로고    scopus 로고
    • Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion
    • 2-s2.0-59449083445
    • Jang B.-C., Park J.-G., Song D.-K., Baek W.-K., Yoo S. K., Jung K.-H., Park G.-Y., Lee T.-Y., Suh S.-I., Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion. Toxicology in Vitro 2009 23 2 281 287 10.1016/j.tiv.2008.12.013 2-s2.0-59449083445
    • (2009) Toxicology in Vitro , vol.23 , Issue.2 , pp. 281-287
    • Jang, B.-C.1    Park, J.-G.2    Song, D.-K.3    Baek, W.-K.4    Yoo, S.K.5    Jung, K.-H.6    Park, G.-Y.7    Lee, T.-Y.8    Suh, S.-I.9
  • 46
    • 81855185596 scopus 로고    scopus 로고
    • Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion
    • 2-s2.0-81855185596
    • Sun M., Liu C., Nadiminty N., Lou W., Zhu Y., Yang J., Evans C. P., Zhou Q., Gao A. C., Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion. The Prostate 2012 72 1 82 89 10.1002/pros.21409 2-s2.0-81855185596
    • (2012) The Prostate , vol.72 , Issue.1 , pp. 82-89
    • Sun, M.1    Liu, C.2    Nadiminty, N.3    Lou, W.4    Zhu, Y.5    Yang, J.6    Evans, C.P.7    Zhou, Q.8    Gao, A.C.9
  • 49
    • 12444257014 scopus 로고    scopus 로고
    • Antioxidants inhibit fatty acid and glucose-mediated induction of neutral endopeptidase gene expression in human microvascular endothelial cells
    • 2-s2.0-12444257014
    • Muangman P., Tamura R. N., Gibran N. S., Antioxidants inhibit fatty acid and glucose-mediated induction of neutral endopeptidase gene expression in human microvascular endothelial cells. Journal of the American College of Surgeons 2005 200 2 208 215 10.1016/j.jamcollsurg.2004.09.043 2-s2.0-12444257014
    • (2005) Journal of the American College of Surgeons , vol.200 , Issue.2 , pp. 208-215
    • Muangman, P.1    Tamura, R.N.2    Gibran, N.S.3


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