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Volumn 30, Issue 11, 2014, Pages 1024-1033

Cilia and renal cysts;Cils et kystes rénaux

Author keywords

[No Author keywords available]

Indexed keywords

SIGNAL PEPTIDE; SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

EID: 84911121383     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/20143011017     Document Type: Article
Times cited : (7)

References (74)
  • 1
    • 84878332706 scopus 로고    scopus 로고
    • The role of the cilium in normal and abnormal cell cycles: Emphasis on renal cystic pathologies
    • Pan J, Seeger-Nukpezah T, Golemis EA. The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies. Cell Mol Life Sci 2013; 70: 1849-1874.
    • (2013) Cell Mol Life Sci , vol.70 , pp. 1849-1874
    • Pan, J.1    Seeger-Nukpezah, T.2    Golemis, E.A.3
  • 3
    • 77249103612 scopus 로고    scopus 로고
    • Molecular advances in autosomal dominant polycystic kidney disease
    • Gallagher AR, Germino GG, Somlo S. Molecular advances in autosomal dominant polycystic kidney disease. Adv Chronic Kidney Dis 2010; 17: 118-130.
    • (2010) Adv Chronic Kidney Dis , vol.17 , pp. 118-130
    • Gallagher, A.R.1    Germino, G.G.2    Somlo, S.3
  • 4
    • 0036175934 scopus 로고    scopus 로고
    • The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells
    • Nickel C, Benzing T, Sellin L, et al. The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells. J Clin Invest 2002; 109: 481-489.
    • (2002) J Clin Invest , vol.109 , pp. 481-489
    • Nickel, C.1    Benzing, T.2    Sellin, L.3
  • 5
    • 84877056647 scopus 로고    scopus 로고
    • Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation
    • Streets AJ, Wessely O, Peters DJ, Ong AC. Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation. Hum Mol Genet 2013; 22: 1924-1939.
    • (2013) Hum Mol Genet , vol.22 , pp. 1924-1939
    • Streets, A.J.1    Wessely, O.2    Peters, D.J.3    Ong, A.C.4
  • 6
    • 84876990650 scopus 로고    scopus 로고
    • Polycystic kidney disease: Polycystin-1 and polycystin-2-it's complicated
    • Watnick TJ, Germino GG. Polycystic kidney disease: Polycystin-1 and polycystin-2-it's complicated. Nat Rev Nephrol 2013; 9: 249-250.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 249-250
    • Watnick, T.J.1    Germino, G.G.2
  • 7
    • 33750391715 scopus 로고    scopus 로고
    • Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin
    • Wu Y, Dai XQ, Li Q, et al. Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin. Hum Mol Genet 2006; 15: 3280-3292.
    • (2006) Hum Mol Genet , vol.15 , pp. 3280-3292
    • Wu, Y.1    Dai, X.Q.2    Li, Q.3
  • 8
    • 70450162111 scopus 로고    scopus 로고
    • Nephrocystin-1 and nephrocystin-4 are required for epithelial morphogenesis and associate with PALS1/PATJ and Par6
    • Delous M, Hellman NE, Gaude HM, et al. Nephrocystin-1 and nephrocystin-4 are required for epithelial morphogenesis and associate with PALS1/PATJ and Par6. Hum Mol Genet 2009; 18: 4711-4723.
    • (2009) Hum Mol Genet , vol.18 , pp. 4711-4723
    • Delous, M.1    Hellman, N.E.2    Gaude, H.M.3
  • 9
    • 84867718106 scopus 로고    scopus 로고
    • 3D spheroid defects in NPHP knockdown cells are rescued by the somatostatin receptor agonist octreotide
    • Ghosh AK, Hurd T, Hildebrandt F. 3D spheroid defects in NPHP knockdown cells are rescued by the somatostatin receptor agonist octreotide. Am J Physiol Renal Physiol 2012; 303: F1225-F1229.
    • (2012) Am J Physiol Renal Physiol , vol.303 , pp. 1225-F1229
    • Ghosh, A.K.1    Hurd, T.2    Hildebrandt, F.3
  • 10
    • 78650924694 scopus 로고    scopus 로고
    • Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome
    • Cui C, Chatterjee B, Francis D, et al. Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome. Dis Model Mech 2011; 4: 43-56.
    • (2011) Dis Model Mech , vol.4 , pp. 43-56
    • Cui, C.1    Chatterjee, B.2    Francis, D.3
  • 11
    • 3042618920 scopus 로고    scopus 로고
    • Renal cysts of inv/inv mice resemble early infantile nephronophthisis
    • Phillips CL, Miller KJ, Filson AJ, et al. Renal cysts of inv/inv mice resemble early infantile nephronophthisis. J Am Soc Nephrol 2004; 15: 1744-1755.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1744-1755
    • Phillips, C.L.1    Miller, K.J.2    Filson, A.J.3
  • 13
    • 0036785149 scopus 로고    scopus 로고
    • The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
    • Yoder BK, Hou X, Guay-Woodford LM. The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J Am Soc Nephrol 2002; 13: 2508-2516.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2508-2516
    • Yoder, B.K.1    Hou, X.2    Guay-Woodford, L.M.3
  • 14
    • 0034735526 scopus 로고    scopus 로고
    • Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella
    • Pazour GJ, Dickert BL, Vucica Y, et al. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol 2000; 151: 709-718.
    • (2000) J Cell Biol , vol.151 , pp. 709-718
    • Pazour, G.J.1    Dickert, B.L.2    Vucica, Y.3
  • 15
    • 84890219086 scopus 로고    scopus 로고
    • Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans
    • Halbritter J, Bizet AA, Schmidts M, et al. Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans. Am J Hum Genet 2013; 93: 915-925.
    • (2013) Am J Hum Genet , vol.93 , pp. 915-925
    • Halbritter, J.1    Bizet, A.A.2    Schmidts, M.3
  • 16
    • 84876338226 scopus 로고    scopus 로고
    • Combined NGS approaches identify mutations in the intraflagellar transport gene IFT140 in skeletal ciliopathies with early progressive kidney disease
    • Schmidts M, Frank V, Eisenberger T, et al. Combined NGS approaches identify mutations in the intraflagellar transport gene IFT140 in skeletal ciliopathies with early progressive kidney disease. Hum Mutat 2013; 34: 714-724.
    • (2013) Hum Mutat , vol.34 , pp. 714-724
    • Schmidts, M.1    Frank, V.2    Eisenberger, T.3
  • 17
    • 56149097603 scopus 로고    scopus 로고
    • Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
    • Jonassen JA, SanAgustin J, Follit JA, Pazour GJ. Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease. J Cell Biol 2008; 183: 377-384.
    • (2008) J Cell Biol , vol.183 , pp. 377-384
    • Jonassen, J.A.1    Sanagustin, J.2    Follit, J.A.3    Pazour, G.J.4
  • 18
    • 84859863721 scopus 로고    scopus 로고
    • Disruption of IFT complex A causes cystic kidneys without mitotic spindle misorientation
    • Jonassen JA, SanAgustin J, Baker SP, Pazour GJ. Disruption of IFT complex A causes cystic kidneys without mitotic spindle misorientation. J Am Soc Nephrol 2012; 23: 641-651.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 641-651
    • Jonassen, J.A.1    Sanagustin, J.2    Baker, S.P.3    Pazour, G.J.4
  • 19
    • 84911174078 scopus 로고    scopus 로고
    • A Homozygous missense mutation in the ciliary gene TTC21B causes familial FSGS
    • Cong EH, Bizet AA, Boyer O, et al. A Homozygous missense mutation in the ciliary gene TTC21B causes familial FSGS. J Am Soc Nephrol 2014; Doi: 10.1681/ASN.2013101126.
    • (2014) J Am Soc Nephrol
    • Cong, E.H.1    Bizet, A.A.2    Boyer, O.3
  • 20
    • 84873805725 scopus 로고    scopus 로고
    • Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system
    • Costantini F. Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system. Wiley Interdisc Rev Dev Biol 2012; 1: 693-713.
    • (2012) Wiley Interdisc Rev Dev Biol , vol.1 , pp. 693-713
    • Costantini, F.1
  • 21
    • 84861117364 scopus 로고    scopus 로고
    • + exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease
    • + exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease. Am J Physiol 2006; 302: C1436-C1451.
    • (2006) Am J Physiol , vol.302 , pp. 1436-C1451
    • Olteanu, D.1    Liu, X.2    Liu, W.3
  • 22
    • 0031252295 scopus 로고    scopus 로고
    • Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation
    • Lu W, Peissel B, Babakhanlou H, et al. Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation. Nat Genet 1997; 17: 179-181.
    • (1997) Nat Genet , vol.17 , pp. 179-181
    • Lu, W.1    Peissel, B.2    Babakhanlou, H.3
  • 23
    • 36849037019 scopus 로고    scopus 로고
    • A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1
    • Piontek K, Menezes LF, Garcia-Gonzalez MA, et al. A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1. Nat Med 2007; 13: 1490-1495.
    • (2007) Nat Med , vol.13 , pp. 1490-1495
    • Piontek, K.1    Menezes, L.F.2    Garcia-Gonzalez, M.A.3
  • 24
    • 36249030528 scopus 로고    scopus 로고
    • Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice
    • Lantinga-van Leeuwen IS, Leonhard WN, van der Wal A, et al. Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice. Hum Mol Genet 2007; 16: 3188-3196.
    • (2007) Hum Mol Genet , vol.16 , pp. 3188-3196
    • Lantinga-Van Leeuwen, I.S.1    Leonhard, W.N.2    Van Der Wal, A.3
  • 25
    • 34548490748 scopus 로고    scopus 로고
    • Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease
    • Davenport JR, Watts AJ, Roper VC, et al. Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Curr Biol 2007; 17: 1586-1594.
    • (2007) Curr Biol , vol.17 , pp. 1586-1594
    • Davenport, J.R.1    Watts, A.J.2    Roper, V.C.3
  • 26
    • 44349116202 scopus 로고    scopus 로고
    • Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia
    • Patel V, Li L, Cobo-Stark P, et al. Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum Mol Genet 2008; 17: 1578-1590.
    • (2008) Hum Mol Genet , vol.17 , pp. 1578-1590
    • Patel, V.1    Li, L.2    Cobo-Stark, P.3
  • 27
    • 77249115100 scopus 로고    scopus 로고
    • Polycystic kidney disease, cilia, and planar polarity
    • Menezes LF, Germino GG. Polycystic kidney disease, cilia, and planar polarity. Methods Cell Biol 2009; 94: 273-297.
    • (2009) Methods Cell Biol , vol.94 , pp. 273-297
    • Menezes, L.F.1    Germino, G.G.2
  • 28
    • 0037884961 scopus 로고    scopus 로고
    • Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
    • Lin F, Hiesberger T, Cordes K, et al. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 2003; 100: 5286-5291.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5286-5291
    • Lin, F.1    Hiesberger, T.2    Cordes, K.3
  • 29
    • 84868613964 scopus 로고    scopus 로고
    • Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity
    • Hopp K, Ward CJ, Hommerding CJ, et al. Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity. J Clin Invest 2012; 122: 4257-4273.
    • (2012) J Clin Invest , vol.122 , pp. 4257-4273
    • Hopp, K.1    Ward, C.J.2    Hommerding, C.J.3
  • 30
    • 84878760611 scopus 로고    scopus 로고
    • Kif3a controls murine nephron number via GLI3 repressor, cell survival, gene expression in a lineage-specific manner
    • Chi L, Galtseva A, Chen L, et al. Kif3a controls murine nephron number via GLI3 repressor, cell survival, gene expression in a lineage-specific manner. PloS One 2013; 8: e65448.
    • (2013) PloS One , vol.8 , pp. 65448
    • Chi, L.1    Galtseva, A.2    Chen, L.3
  • 31
    • 67649844614 scopus 로고    scopus 로고
    • Polycystins and primary cilia: Primers for cell cycle progression
    • Zhou J. Polycystins and primary cilia: primers for cell cycle progression. Annu Rev Physiol 2009; 71: 83-113.
    • (2009) Annu Rev Physiol , vol.71 , pp. 83-113
    • Zhou, J.1
  • 32
    • 84920083456 scopus 로고    scopus 로고
    • The Primary cilium calcium channels and their role in flow sensing
    • Patel A. The Primary cilium calcium channels and their role in flow sensing. Pflugers Arch 2014; Doi: 10.1007/s00424-014-1516-0.
    • (2014) Pflugers Arch
    • Patel, A.1
  • 33
    • 70350346866 scopus 로고    scopus 로고
    • Polycystin-1 and-2 dosage regulates pressure sensing
    • Sharif-Naeini R, Folgering JH, Bichet D, et al. Polycystin-1 and-2 dosage regulates pressure sensing. Cell 2009; 139: 587-596.
    • (2009) Cell , vol.139 , pp. 587-596
    • Sharif-Naeini, R.1    Folgering, J.H.2    Bichet, D.3
  • 34
    • 0037317302 scopus 로고    scopus 로고
    • Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
    • Nauli SM, Alenghat FJ, Luo Y, et al. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet 2003; 33: 129-137.
    • (2003) Nat Genet , vol.33 , pp. 129-137
    • Nauli, S.M.1    Alenghat, F.J.2    Luo, Y.3
  • 35
    • 79960590689 scopus 로고    scopus 로고
    • Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases
    • Choi YH, Suzuki A, Hajarnis S, et al. Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases. Proc Natl Acad Sci USA 2011; 108: 10679-10684.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 10679-10684
    • Choi, Y.H.1    Suzuki, A.2    Hajarnis, S.3
  • 36
    • 84891818486 scopus 로고    scopus 로고
    • Strategies targeting cAMP signaling in the treatment of polycystic kidney disease
    • Torres VE, Harris PC. Strategies targeting cAMP signaling in the treatment of polycystic kidney disease. J Am Soc Nephrol 2014; 25: 18-32.
    • (2014) J Am Soc Nephrol , vol.25 , pp. 18-32
    • Torres, V.E.1    Harris, P.C.2
  • 37
    • 77954510897 scopus 로고    scopus 로고
    • Emerging evidence of a link between the polycystins, the mTOR pathways
    • Boletta A., Emerging evidence of a link between the polycystins, the mTOR pathways. PathoGenetics 2009; 2: 6.
    • (2009) Patho Genetics , vol.2 , pp. 6
    • Boletta, A.1
  • 38
    • 67649872366 scopus 로고    scopus 로고
    • Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis
    • Gattone VH, 2nd, Sinders RM, Hornberger TA, Robling AG. Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis. Kidney Int 2009; 76: 178-182.
    • (2009) Kidney Int. , vol.76 , pp. 178-182
    • Gattone, I.I.V.H.1    Sinders, R.M.2    Hornberger, T.A.3    Robling, A.G.4
  • 39
    • 78149259013 scopus 로고    scopus 로고
    • Primary cilia regulate mTORC1 activity and cell size through Lkb1
    • Boehlke C, Kotsis F, Patel V, et al. Primary cilia regulate mTORC1 activity and cell size through Lkb1. Nat Cell Biol 2010; 12: 1115-1122.
    • (2010) Nat Cell Biol , vol.12 , pp. 1115-1122
    • Boehlke, C.1    Kotsis, F.2    Patel, V.3
  • 40
    • 84883455352 scopus 로고    scopus 로고
    • Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease
    • Ma M, Tian X, Igarashi P, et al. Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease. Nat Genet 2013; 45: 1004-1012.
    • (2013) Nat Genet , vol.45 , pp. 1004-1012
    • Ma, M.1    Tian, X.2    Igarashi, P.3
  • 41
    • 84874594253 scopus 로고    scopus 로고
    • Proximal tubule proliferation is insufficient to induce rapid cyst formation after cilia disruption
    • Sharma N, Malarkey EB, Berbari NF, et al. Proximal tubule proliferation is insufficient to induce rapid cyst formation after cilia disruption. J Am Soc Nephrol 2013; 24: 456-464.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 456-464
    • Sharma, N.1    Malarkey, E.B.2    Berbari, N.F.3
  • 42
    • 75749126127 scopus 로고    scopus 로고
    • Galectin-3, a novel centrosome-associated protein, required for epithelial morphogenesis
    • Koch A, Poirier F, Jacob R, Delacour D. Galectin-3, a novel centrosome-associated protein, required for epithelial morphogenesis. Mol Biol Cell 2010; 21: 219-231.
    • (2010) Mol Biol Cell , vol.21 , pp. 219-231
    • Koch, A.1    Poirier, F.2    Jacob, R.3    Delacour, D.4
  • 43
    • 84900338585 scopus 로고    scopus 로고
    • Aberrant expression of laminin-332 promotes cell proliferation and cyst growth in ARPKD
    • Vijayakumar S, Dang S, Marinkovich MP, et al. Aberrant expression of laminin-332 promotes cell proliferation and cyst growth in ARPKD. Am J Physiol Renal Physiol 2014; 306: F640-F654.
    • (2014) Am J Physiol Renal Physiol , vol.306 , pp. 640-F654
    • Vijayakumar, S.1    Dang, S.2    Marinkovich, M.P.3
  • 44
    • 80052270877 scopus 로고    scopus 로고
    • Polycystins, focal adhesions and extracellular matrix interactions
    • Drummond IA. Polycystins, focal adhesions and extracellular matrix interactions. Biochim Biophys Acta 2011; 1812: 1322-1326.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 1322-1326
    • Drummond, I.A.1
  • 45
    • 84898815152 scopus 로고    scopus 로고
    • Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-pacsin 2-N-wasp complex
    • Yao G, Su X, Nguyen V, et al. Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-pacsin 2-N-wasp complex. Hum Mol Genet 2014; 23: 2769-2779.
    • (2014) Hum Mol Genet , vol.23 , pp. 2769-2779
    • Yao, G.1    Su, X.2    Nguyen, V.3
  • 46
    • 29444450890 scopus 로고    scopus 로고
    • Defective planar cell polarity in polycystic kidney disease
    • Fischer E, Legue E, Doyen A, et al. Defective planar cell polarity in polycystic kidney disease. Nat Genet 2006; 38: 21-23.
    • (2006) Nat Genet , vol.38 , pp. 21-23
    • Fischer, E.1    Legue, E.2    Doyen, A.3
  • 47
    • 80053553994 scopus 로고    scopus 로고
    • The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries
    • Nigg EA, Stearns T. The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries. Nat Cell Biol 2011; 13: 1154-1160.
    • (2011) Nat Cell Biol , vol.13 , pp. 1154-1160
    • Nigg, E.A.1    Stearns, T.2
  • 48
    • 67649878597 scopus 로고    scopus 로고
    • Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis
    • Karner CM, Chirumamilla R, Aoki S, et al. Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis. Nat Genet 2009; 41: 793-799.
    • (2009) Nat Genet , vol.41 , pp. 793-799
    • Karner, C.M.1    Chirumamilla, R.2    Aoki, S.3
  • 49
    • 77949361893 scopus 로고    scopus 로고
    • Loss of oriented cell division does not initiate cyst formation
    • Nishio S, Tian X, Gallagher AR, et al. Loss of oriented cell division does not initiate cyst formation. J Am Soc Nephrol 2010; 21: 295-302.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 295-302
    • Nishio, S.1    Tian, X.2    Gallagher, A.R.3
  • 50
    • 84870478180 scopus 로고    scopus 로고
    • Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension
    • Lienkamp SS, Liu K, Karner CM, et al. Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension. Nat Genet 2012; 44: 1382-1387.
    • (2012) Nat Genet , vol.44 , pp. 1382-1387
    • Lienkamp, S.S.1    Liu, K.2    Karner, C.M.3
  • 51
    • 58849125300 scopus 로고    scopus 로고
    • Collective cell migration drives morphogenesis of the kidney nephron
    • Vasilyev A, Liu Y, Mudumana S, et al. Collective cell migration drives morphogenesis of the kidney nephron. PLoS Biol 2009; 7: e9.
    • (2009) PLoS Biol , vol.7 , pp. 9
    • Vasilyev, A.1    Liu, Y.2    Mudumana, S.3
  • 52
    • 84886654516 scopus 로고    scopus 로고
    • Polycystin-1 binds Par3/aPKC, controls convergent extension during renal tubular morphogenesis
    • Castelli M, Boca M, Chiaravalli M, et al. Polycystin-1 binds Par3/aPKC, controls convergent extension during renal tubular morphogenesis. Nat Commun 2013; 4: 2658.
    • (2013) Nat Commun , vol.4 , pp. 2658
    • Castelli, M.1    Boca, M.2    Chiaravalli, M.3
  • 53
    • 84903158774 scopus 로고    scopus 로고
    • Developmental signaling: Does it bridge the gap between cilia dysfunction and renal cystogenesis ?
    • Tran PV, Sharma M, Li X, Calvet JP. Developmental signaling: Does it bridge the gap between cilia dysfunction and renal cystogenesis ?. Birth Defects Res C Embryo Today 2014; 102: 159-173.
    • (2014) Birth Defects Res C Embryo Today , vol.102 , pp. 159-173
    • Tran, P.V.1    Sharma, M.2    Li, X.3    Calvet, J.P.4
  • 54
    • 70350217255 scopus 로고    scopus 로고
    • GLI3 repressor controls nephron number via regulation of Wnt11, Ret in ureteric tip cells
    • Cain JE, Islam E, Haxho F, et al. GLI3 repressor controls nephron number via regulation of Wnt11, Ret in ureteric tip cells. PloS One 2009; 4: e7313.
    • (2009) PloS One , vol.4 , pp. 7313
    • Cain, J.E.1    Islam, E.2    Haxho, F.3
  • 55
    • 84921802641 scopus 로고    scopus 로고
    • Downregulating hedgehog signaling reduces renal ccystogenic potential of mouse models
    • Tran PV, Talbott GC, Turbe-Doan A, et al. Downregulating hedgehog signaling reduces renal ccystogenic potential of mouse models. J Am Soc Nephrol 2014; Doi: 10.1681/ASN.2013070735.
    • (2014) J Am Soc Nephrol
    • Tran, P.V.1    Talbott, G.C.2    Turbe-Doan, A.3
  • 56
    • 80053948530 scopus 로고    scopus 로고
    • Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs
    • Li B, Rauhauser AA, Dai J, et al. Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs. Hum Mol Genet 2011; 20: 4155-4166.
    • (2011) Hum Mol Genet , vol.20 , pp. 4155-4166
    • Li, B.1    Rauhauser, A.A.2    Dai, J.3
  • 57
    • 75149149456 scopus 로고    scopus 로고
    • Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as Indian hedgehog
    • Chan SK, Riley PR, Price KL, et al. Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as Indian hedgehog. Am J Physiol Renal Physiol 2010; 298: F346-F356.
    • (2010) Am J Physiol Renal Physiol , vol.298 , pp. 346-F356
    • Chan, S.K.1    Riley, P.R.2    Price, K.L.3
  • 58
    • 20944435539 scopus 로고    scopus 로고
    • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
    • Simons M, Gloy J, Ganner A, et al. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat Genet 2005; 37: 537-543.
    • (2005) Nat Genet , vol.37 , pp. 537-543
    • Simons, M.1    Gloy, J.2    Ganner, A.3
  • 59
    • 77955418239 scopus 로고    scopus 로고
    • Cystic kidney disease: The role of Wnt signaling
    • Lancaster MA, Gleeson JG. Cystic kidney disease: the role of Wnt signaling. Trends Mol Med 2010; 16: 349-360.
    • (2010) Trends Mol Med , vol.16 , pp. 349-360
    • Lancaster, M.A.1    Gleeson, J.G.2
  • 60
    • 79954596902 scopus 로고    scopus 로고
    • The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice
    • Sugiyama N, Tsukiyama T, Yamaguchi TP, Yokoyama T. The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice. Kidney Int 2011; 79: 957-965.
    • (2011) Kidney Int , vol.79 , pp. 957-965
    • Sugiyama, N.1    Tsukiyama, T.2    Yamaguchi, T.P.3    Yokoyama, T.4
  • 61
    • 79959785834 scopus 로고    scopus 로고
    • T-cell factor/beta-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease
    • Miller MM, Iglesias DM, Zhang Z, et al. T-cell factor/beta-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease. Kidney Int 2011; 80: 146-153.
    • (2011) Kidney Int. , vol.80 , pp. 146-153
    • Miller, M.M.1    Iglesias, D.M.2    Zhang, Z.3
  • 62
    • 79958745491 scopus 로고    scopus 로고
    • Control of the Wnt pathways by nephrocystin-4 is required for morphogenesis of the zebrafish pronephros
    • Burckle C, Gaude HM, Vesque C, et al. Control of the Wnt pathways by nephrocystin-4 is required for morphogenesis of the zebrafish pronephros. Hum Mol Genet 2011; 20: 2611-2627.
    • (2011) Hum Mol Genet , vol.20 , pp. 2611-2627
    • Burckle, C.1    Gaude, H.M.2    Vesque, C.3
  • 63
    • 78149237338 scopus 로고    scopus 로고
    • The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation
    • Yates LL, Papakrivopoulou J, Long DA, et al. The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. Hum Mol Genet 2010; 19: 4663-4676.
    • (2010) Hum Mol Genet , vol.19 , pp. 4663-4676
    • Yates, L.L.1    Papakrivopoulou, J.2    Long, D.A.3
  • 64
    • 79951532109 scopus 로고    scopus 로고
    • Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development
    • Mao Y, Mulvaney J, Zakaria S, et al. Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. Development 2011; 138: 947-957.
    • (2011) Development , vol.138 , pp. 947-957
    • Mao, Y.1    Mulvaney, J.2    Zakaria, S.3
  • 65
    • 84859859241 scopus 로고    scopus 로고
    • Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity
    • Saburi S, Hester I, Goodrich L, McNeill H. Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity. Development 2012; 139: 1806-1820.
    • (2012) Development , vol.139 , pp. 1806-1820
    • Saburi, S.1    Hester, I.2    Goodrich, L.3    McNeill, H.4
  • 66
    • 0037377655 scopus 로고    scopus 로고
    • Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice
    • Brown NE, Murcia NS. Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice. Kidney Int 2003; 63: 1220-1229.
    • (2003) Kidney Int , vol.63 , pp. 1220-1229
    • Brown, N.E.1    Murcia, N.S.2
  • 67
    • 84878434156 scopus 로고    scopus 로고
    • Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy
    • Rowe I, Chiaravalli M, Mannella V, et al. Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy. Nat Med 2014; 19: 488-493.
    • (2014) Nat Med , vol.19 , pp. 488-493
    • Rowe, I.1    Chiaravalli, M.2    Mannella, V.3
  • 68
    • 78651387406 scopus 로고    scopus 로고
    • Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney
    • Nagalakshmi VK, Ren Q, Pugh MM, et al. Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney. Kidney Int 2011; 79: 317-330.
    • (2011) Kidney Int. , vol.79 , pp. 317-330
    • Nagalakshmi, V.K.1    Ren, Q.2    Pugh, M.M.3
  • 70
    • 84911181245 scopus 로고    scopus 로고
    • Complexité génétique des ciliopathies et identification de nouveaux gènes
    • Bachmann-Gagescu R. Complexité génétique des ciliopathies et identification de nouveaux gènes. Med Sci (Paris) 2014; 30: 1011-1023.
    • (2014) Med Sci (Paris) , vol.30 , pp. 1011-1023
    • Bachmann-Gagescu, R.1
  • 71
    • 84911115528 scopus 로고    scopus 로고
    • Élongation de l'axonème et dynamique du transport intraflagellaire
    • Fort C, Bastin P. Élongation de l'axonème et dynamique du transport intraflagellaire. Med Sci (Paris) 2014; 30: 955-961.
    • (2014) Med Sci (Paris) , vol.30 , pp. 955-961
    • Fort, C.1    Bastin, P.2
  • 72
    • 84911152857 scopus 로고    scopus 로고
    • De nouvelles fonctions extraciliaires pour les proteínes ciliaires. Quelles conséquences sur l'apparition de ciliopathies ?
    • Taulet N, Delaval B. De nouvelles fonctions extraciliaires pour les proteínes ciliaires. Quelles conséquences sur l'apparition de ciliopathies ? Med Sci (Paris) 2014; 30: 1040-1050.
    • (2014) Med Sci (Paris) , vol.30 , pp. 1040-1050
    • Taulet, N.1    Delaval, B.2
  • 73
    • 84911133983 scopus 로고    scopus 로고
    • Les liens multiples entre les cils et la polarité planaire cellulaire
    • Ezan J, Montcouquiol M. Les liens multiples entre les cils et la polarité planaire cellulaire. Med Sci (Paris) 2014; 30: 1004-1010.
    • (2014) Med Sci (Paris) , vol.30 , pp. 1004-1010
    • Ezan, J.1    Montcouquiol, M.2
  • 74
    • 84911147043 scopus 로고    scopus 로고
    • Le cil primaire, orchestrateur de la morphogenèse cérébrale
    • Laclef C. Le cil primaire, orchestrateur de la morphogenèse cérébrale. Med Sci (Paris) 2014; 30: 980-990.
    • (2014) Med Sci (Paris) , vol.30 , pp. 980-990
    • Laclef, C.1


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