메뉴 건너뛰기




Volumn 289, Issue 46, 2014, Pages 31983-31994

Plasma membrane cholesterol as a regulator of human and rodent P2X7 receptor activation and sensitization

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELL MEMBRANES; CHEMICAL ACTIVATION;

EID: 84911059063     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.574699     Document Type: Article
Times cited : (63)

References (58)
  • 1
    • 0036788971 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors
    • North, R. A. (2002) Molecular physiology of P2X receptors. Physiol. Rev. 82, 1013-1067
    • (2002) Physiol. Rev. , vol.82 , pp. 1013-1067
    • North, R.A.1
  • 2
    • 67649639047 scopus 로고    scopus 로고
    • Signaling at purinergic P2X receptors
    • Surprenant, A., and North, R. A. (2009) Signaling at purinergic P2X receptors. Annu. Rev. Physiol. 71, 333-359
    • (2009) Annu. Rev. Physiol. , vol.71 , pp. 333-359
    • Surprenant, A.1    North, R.A.2
  • 6
    • 79955931903 scopus 로고    scopus 로고
    • Activation of P2X receptors induces apoptosis in human retinal pigment epithelium. Invest
    • Yang, D., Elner, S. G., Clark, A. J., Hughes, B. A., Petty, H. R., and Elner, V. M. (2011) Activation of P2X receptors induces apoptosis in human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 52, 1522-1530
    • (2011) Ophthalmol. Vis. Sci. , vol.52 , pp. 1522-1530
    • Yang, D.1    Elner, S.G.2    Clark, A.J.3    Hughes, B.A.4    Petty, H.R.5    Elner, V.M.6
  • 7
    • 79960019927 scopus 로고    scopus 로고
    • P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice
    • Furlan-Freguia, C., Marchese, P., Gruber, A., Ruggeri, Z. M., and Ruf, W. (2011) P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. J. Clin. Invest. 121, 2932-2944
    • (2011) J. Clin. Invest. , vol.121 , pp. 2932-2944
    • Furlan-Freguia, C.1    Marchese, P.2    Gruber, A.3    Ruggeri, Z.M.4    Ruf, W.5
  • 8
    • 21844450590 scopus 로고    scopus 로고
    • Basal activation activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth
    • Adinolfi, E., Callegari, M. G., Ferrari, D., Bolognesi, C., Minelli, M., Wieckowski, M. R., Pinton, P., Rizzuto, R., and Di Virgilio, F. (2005) Basal activation activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth. Mol. Biol. Cell 16, 3260-3272
    • (2005) Mol. Biol. Cell , vol.16 , pp. 3260-3272
    • Adinolfi, E.1    Callegari, M.G.2    Ferrari, D.3    Bolognesi, C.4    Minelli, M.5    Wieckowski, M.R.6    Pinton, P.7    Rizzuto, R.8    Di Virgilio, F.9
  • 9
    • 79951827539 scopus 로고    scopus 로고
    • Purinergic P2X7 receptor regulates lung surfactant secretion in a paracrine manner
    • Mishra, A., Chintagari, N. R., Guo, Y., Weng, T., Su, L., and Liu, L. (2011) Purinergic P2X7 receptor regulates lung surfactant secretion in a paracrine manner. J. Cell Sci. 124, 657-668
    • (2011) J. Cell Sci. , vol.124 , pp. 657-668
    • Mishra, A.1    Chintagari, N.R.2    Guo, Y.3    Weng, T.4    Su, L.5    Liu, L.6
  • 12
    • 59449086148 scopus 로고    scopus 로고
    • The P2X7 receptor channel pore dilates under physiological ion conditions
    • Yan, Z., Li, S., Liang, Z., Tomić, M., and Stojilkovic, S. S. (2008) The P2X7 receptor channel pore dilates under physiological ion conditions. J. Gen. Physiol. 132, 563-573
    • (2008) J. Gen. Physiol. , vol.132 , pp. 563-573
    • Yan, Z.1    Li, S.2    Liang, Z.3    Tomić, M.4    Stojilkovic, S.S.5
  • 13
    • 77952931867 scopus 로고    scopus 로고
    • C-terminal calmodulin-binding motif differentially controls human and rat P2X7 receptor current facilitation
    • Roger, S., Gillet, L., Baroja-Mazo, A., Surprenant, A., and Pelegrin, P. (2010) C-terminal calmodulin-binding motif differentially controls human and rat P2X7 receptor current facilitation. J. Biol. Chem. 285, 17514-17524
    • (2010) J. Biol. Chem. , vol.285 , pp. 17514-17524
    • Roger, S.1    Gillet, L.2    Baroja-Mazo, A.3    Surprenant, A.4    Pelegrin, P.5
  • 14
    • 46749144924 scopus 로고    scopus 로고
    • Facilitation of P2X7 receptor currents and membrane blebbing via constitutive and dynamic calmodulin binding
    • Roger, S., Pelegrin, P., and Surprenant, A. (2008) Facilitation of P2X7 receptor currents and membrane blebbing via constitutive and dynamic calmodulin binding. J. Neurosci. 28, 6393-6401
    • (2008) J. Neurosci. , vol.28 , pp. 6393-6401
    • Roger, S.1    Pelegrin, P.2    Surprenant, A.3
  • 15
    • 77958471651 scopus 로고    scopus 로고
    • Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: Chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors
    • Allsopp, R. C., Lalo, U., and Evans, R. J. (2010) Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors. J. Biol. Chem. 285, 32770-32777
    • (2010) J. Biol. Chem. , vol.285 , pp. 32770-32777
    • Allsopp, R.C.1    Lalo, U.2    Evans, R.J.3
  • 18
    • 61449242774 scopus 로고    scopus 로고
    • Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts
    • Gonnord, P., Delarasse, C., Auger, R., Benihoud, K., Prigent, M., Cuif, M. H., Lamaze, C., and Kanellopoulos, J. M. (2009) Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts. FASEB J. 23, 795-805
    • (2009) FASEB J. , vol.23 , pp. 795-805
    • Gonnord, P.1    Delarasse, C.2    Auger, R.3    Benihoud, K.4    Prigent, M.5    Cuif, M.H.6    Lamaze, C.7    Kanellopoulos, J.M.8
  • 19
    • 80053173506 scopus 로고    scopus 로고
    • Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model
    • Gnanasekaran, A., Sundukova, M., van den Maagdenberg, A. M., Fabbretti, E., and Nistri, A. (2011) Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model. Mol. Pain 7, 77
    • (2011) Mol. Pain , vol.7 , pp. 77
    • Gnanasekaran, A.1    Sundukova, M.2    Van Den Maagdenberg, A.M.3    Fabbretti, E.4    Nistri, A.5
  • 21
    • 74849118341 scopus 로고    scopus 로고
    • Lipid rafts as a membrane-organizing principle
    • Lingwood, D., and Simons, K. (2010) Lipid rafts as a membrane-organizing principle. Science 327, 46-50
    • (2010) Science , vol.327 , pp. 46-50
    • Lingwood, D.1    Simons, K.2
  • 22
    • 1642354334 scopus 로고    scopus 로고
    • Lipid rafts: Heterogeneity on the high seas
    • Pike, L. J. (2004) Lipid rafts: heterogeneity on the high seas. Biochem. J. 378, 281-292
    • (2004) Biochem. J. , vol.378 , pp. 281-292
    • Pike, L.J.1
  • 23
    • 48949116921 scopus 로고    scopus 로고
    • Characterization of the molecular interaction between caveolin-1 and the P2X receptors 4 and 7 in E10 mouse lung alveolar epithelial cells
    • Barth, K., Weinhold, K., Guenther, A., Linge, A., Gereke, M., and Kasper, M. (2008) Characterization of the molecular interaction between caveolin-1 and the P2X receptors 4 and 7 in E10 mouse lung alveolar epithelial cells. Int. J. Biochem. Cell Biol. 40, 2230-2239
    • (2008) Int. J. Biochem. Cell Biol. , vol.40 , pp. 2230-2239
    • Barth, K.1    Weinhold, K.2    Guenther, A.3    Linge, A.4    Gereke, M.5    Kasper, M.6
  • 24
    • 34249795198 scopus 로고    scopus 로고
    • Caveolin-1 influences P2X7 receptor expression and localization in mouse lung alveolar epithelial cells
    • Barth, K., Weinhold, K., Guenther, A., Young, M. T., Schnittler, H., and Kasper, M. (2007) Caveolin-1 influences P2X7 receptor expression and localization in mouse lung alveolar epithelial cells. FEBS J. 274, 3021-3033
    • (2007) FEBS J. , vol.274 , pp. 3021-3033
    • Barth, K.1    Weinhold, K.2    Guenther, A.3    Young, M.T.4    Schnittler, H.5    Kasper, M.6
  • 25
    • 33750362901 scopus 로고    scopus 로고
    • P2X7 and phospholipid signalling: The search of the "missing link" in epithelial cells
    • Garcia-Marcos, M., Pochet, S., Marino, A., and Dehaye, J. P. (2006) P2X7 and phospholipid signalling: the search of the "missing link" in epithelial cells. Cell. Signal. 18, 2098-2104
    • (2006) Cell. Signal. , vol.18 , pp. 2098-2104
    • Garcia-Marcos, M.1    Pochet, S.2    Marino, A.3    Dehaye, J.P.4
  • 26
    • 77954685069 scopus 로고    scopus 로고
    • Interaction and interrelation of P2X7 and P2X4 receptor complexes in mouse lung epithelial cells
    • Weinhold, K., Krause-Buchholz, U., Rödel, G., Kasper, M., and Barth, K. (2010) Interaction and interrelation of P2X7 and P2X4 receptor complexes in mouse lung epithelial cells. Cell. Mol. Life Sci. 67, 2631-2642
    • (2010) Cell. Mol. Life Sci. , vol.67 , pp. 2631-2642
    • Weinhold, K.1    Krause-Buchholz, U.2    Rödel, G.3    Kasper, M.4    Barth, K.5
  • 27
    • 80051937076 scopus 로고    scopus 로고
    • Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signalling
    • Fessler, M. B., and Parks, J. S. (2011) Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling. J. Immunol. 187, 1529-1535
    • (2011) J. Immunol. , vol.187 , pp. 1529-1535
    • Fessler, M.B.1    Parks, J.S.2
  • 29
    • 29344454912 scopus 로고    scopus 로고
    • Involvement of de novo ceramide biosynthesis in macrophage death induced by activation of ATP sensitive P2X7 receptor
    • Raymond, M. N., and Le Stunff, H. (2006) Involvement of de novo ceramide biosynthesis in macrophage death induced by activation of ATP sensitive P2X7 receptor. FEBS Lett. 580, 131-136
    • (2006) FEBS Lett. , vol.580 , pp. 131-136
    • Raymond, M.N.1    Le Stunff, H.2
  • 30
    • 33646470605 scopus 로고    scopus 로고
    • ATP-induced apoptosis of thymocytes is mediated by activation of P2X7 receptor and involves de novo ceramide synthesis and mitochondria
    • Lépine, S., Le Stunff, H., Lakatos, B., Sulpice, J. C., and Giraud, F. (2006) ATP-induced apoptosis of thymocytes is mediated by activation of P2X7 receptor and involves de novo ceramide synthesis and mitochondria. Biochim. Biophys. Acta 1761, 73-82
    • (2006) Biochim. Biophys. Acta , vol.1761 , pp. 73-82
    • Lépine, S.1    Le Stunff, H.2    Lakatos, B.3    Sulpice, J.C.4    Giraud, F.5
  • 32
    • 84860998306 scopus 로고    scopus 로고
    • Fluvastatin suppresses native and recombinant human P2X4 receptor function
    • Li, J., and Fountain, S. J. (2012) Fluvastatin suppresses native and recombinant human P2X4 receptor function. Purinergic Signal. 8, 311-316
    • (2013) Purinergic Signal. , vol.8 , pp. 311-316
    • Li, J.1    Fountain, S.J.2
  • 33
    • 24744448897 scopus 로고    scopus 로고
    • Disruption of lipid rafts inhibits P2X1 receptor-mediated currents and arterial vasoconstriction
    • Vial, C., and Evans, R. J. (2005) Disruption of lipid rafts inhibits P2X1 receptor-mediated currents and arterial vasoconstriction. J. Biol. Chem. 280, 30705-30711
    • (2005) J. Biol. Chem. , vol.280 , pp. 30705-30711
    • Vial, C.1    Evans, R.J.2
  • 34
    • 80052197134 scopus 로고    scopus 로고
    • Identification of human P2X1 receptor-interacting proteins reveals a role of the cytoskeleton in receptor regulation
    • Lalo, U., Roberts, J. A., and Evans, R. J. (2011) Identification of human P2X1 receptor-interacting proteins reveals a role of the cytoskeleton in receptor regulation. J. Biol. Chem. 286, 30591-30599
    • (2011) J. Biol. Chem. , vol.286 , pp. 30591-30599
    • Lalo, U.1    Roberts, J.A.2    Evans, R.J.3
  • 35
    • 84867112397 scopus 로고    scopus 로고
    • Splice-variants of the P2X7 receptor reveal differential agonist-dependence and functional coupling with pannexin-1
    • Xu, X. J., Boumechache, M., Robinson, L. E., Marschall, V., Gorecki, D. C., Masin, M., and Murrell-Lagnado, R. (2012) Splice-variants of the P2X7 receptor reveal differential agonist-dependence and functional coupling with pannexin-1. J. Cell Sci. 125, 3776-3789
    • (2013) J. Cell Sci. , vol.125 , pp. 3776-3789
    • Xu, X.J.1    Boumechache, M.2    Robinson, L.E.3    Marschall, V.4    Gorecki, D.C.5    Masin, M.6    Murrell-Lagnado, R.7
  • 36
    • 67649395964 scopus 로고    scopus 로고
    • Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells
    • Boumechache, M., Masin, M., Edwardson, J. M., Górecki, D. C., and Murrell-Lagnado, R. (2009) Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells. J. Biol. Chem. 284, 13446-13454
    • (2009) J. Biol. Chem. , vol.284 , pp. 13446-13454
    • Boumechache, M.1    Masin, M.2    Edwardson, J.M.3    Górecki, D.C.4    Murrell-Lagnado, R.5
  • 37
    • 36549041874 scopus 로고    scopus 로고
    • Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis
    • Qureshi, O. S., Paramasivam, A., Yu, J. C., and Murrell-Lagnado, R. D. (2007) Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis. J. Cell Sci. 120, 3838-3849
    • (2007) J. Cell Sci. , vol.120 , pp. 3838-3849
    • Qureshi, O.S.1    Paramasivam, A.2    Yu, J.C.3    Murrell-Lagnado, R.D.4
  • 38
    • 0037096435 scopus 로고    scopus 로고
    • P2X receptor trafficking in neurons is subunit specific
    • Bobanovic, L. K., Royle, S. J., and Murrell-Lagnado, R. D. (2002) P2X receptor trafficking in neurons is subunit specific. J. Neurosci. 22, 4814-4824
    • (2002) J. Neurosci. , vol.22 , pp. 4814-4824
    • Bobanovic, L.K.1    Royle, S.J.2    Murrell-Lagnado, R.D.3
  • 39
    • 34249064912 scopus 로고    scopus 로고
    • Use of cyclodextrins to manipulate plasma membrane cholesterol content: Evidence, misconceptions and control strategies
    • Zidovetzki, R., and Levitan, I. (2007) Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies. Biochim. Biophys. Acta 1768, 1311-1324
    • (2007) Biochim. Biophys. Acta , vol.1768 , pp. 1311-1324
    • Zidovetzki, R.1    Levitan, I.2
  • 40
    • 68849086814 scopus 로고    scopus 로고
    • Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: This dissociation regulates P2X7 pore formation
    • Gu, B. J., Rathsam, C., Stokes, L., McGeachie, A. B., and Wiley, J. S. (2009) Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: this dissociation regulates P2X7 pore formation. Am. J. Physiol. Cell Physiol. 297, C430-C439
    • (2009) Am. J. Physiol. Cell Physiol. , vol.297 , pp. C430-C439
    • Gu, B.J.1    Rathsam, C.2    Stokes, L.3    McGeachie, A.B.4    Wiley, J.S.5
  • 41
    • 33750473352 scopus 로고    scopus 로고
    • Pannexin-1 mediates large pore formation and interleukin-1- release by the ATP-gated P2X7 receptor
    • Pelegrin, P., and Surprenant, A. (2006) Pannexin-1 mediates large pore formation and interleukin-1- release by the ATP-gated P2X7 receptor. EMBO J. 25, 5071-5082
    • (2006) EMBO J. , vol.25 , pp. 5071-5082
    • Pelegrin, P.1    Surprenant, A.2
  • 43
    • 84862001785 scopus 로고    scopus 로고
    • Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2-and voltage-gatedK-(BK) channels
    • Singh, A. K., McMillan, J., Bukiya, A. N., Burton, B., Parrill, A. L., and Dopico, A. M. (2012) Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2-and voltage-gatedK-(BK) channels. J. Biol. Chem. 287, 20509-20521
    • (2012) J. Biol. Chem. , vol.287 , pp. 20509-20521
    • Singh, A.K.1    McMillan, J.2    Bukiya, A.N.3    Burton, B.4    Parrill, A.L.5    Dopico, A.M.6
  • 44
    • 0031755752 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor function in cholesterol transport: Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern
    • Li, H., and Papadopoulos, V. (1998) Peripheral-type benzodiazepine receptor function in cholesterol transport: identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern. Endocrinology 139, 4991-4997
    • (1998) Endocrinology , vol.139 , pp. 4991-4997
    • Li, H.1    Papadopoulos, V.2
  • 45
    • 79851494039 scopus 로고    scopus 로고
    • Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor
    • Oddi, S., Dainese, E., Fezza, F., Lanuti, M., Barcaroli, D., De Laurenzi, V., Centonze, D., and Maccarrone, M. (2011) Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor. J. Neurochem. 116, 858-865
    • (2011) J. Neurochem. , vol.116 , pp. 858-865
    • Oddi, S.1    Dainese, E.2    Fezza, F.3    Lanuti, M.4    Barcaroli, D.5    De Laurenzi, V.6    Centonze, D.7    Maccarrone, M.8
  • 46
    • 0037164705 scopus 로고    scopus 로고
    • Identification of a conserved domain of the HIV-1 transmembrane protein gp41 which interacts with cholesteryl groups
    • Vincent, N., Genin, C., and Malvoisin, E. (2002) Identification of a conserved domain of the HIV-1 transmembrane protein gp41 which interacts with cholesteryl groups. Biochim. Biophys. Acta 1567, 157-164
    • (2002) Biochim. Biophys. Acta , vol.1567 , pp. 157-164
    • Vincent, N.1    Genin, C.2    Malvoisin, E.3
  • 47
    • 84875345806 scopus 로고    scopus 로고
    • Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor
    • Rokic, M. B., Stojilkovic, S. S., Vavra, V., Kuzyk, P., Tvrdonova, V., and Zemkova, H. (2013) Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor. PLoS One 8, e59411
    • (2013) PLoS One , vol.8 , pp. e59411
    • Rokic, M.B.1    Stojilkovic, S.S.2    Vavra, V.3    Kuzyk, P.4    Tvrdonova, V.5    Zemkova, H.6
  • 48
    • 34548611556 scopus 로고    scopus 로고
    • Regulation of ATPgated P2X receptors by phosphoinositides
    • Zhao, Q., Logothetis, D. E., and Séguéla, P. (2007) Regulation of ATPgated P2X receptors by phosphoinositides. Pflugers Arch. 455, 181-185
    • (2007) Pflugers Arch. , vol.455 , pp. 181-185
    • Zhao, Q.1    Logothetis, D.E.2    Séguéla, P.3
  • 50
    • 84874195644 scopus 로고    scopus 로고
    • P2X7 receptor channels allow direct permeation of nanometer-sized dyes
    • Browne, L. E., Compan, V., Bragg, L., and North, R. A. (2013) P2X7 receptor channels allow direct permeation of nanometer-sized dyes. J. Neurosci. 33, 3557-3566
    • (2013) J. Neurosci. , vol.33 , pp. 3557-3566
    • Browne, L.E.1    Compan, V.2    Bragg, L.3    North, R.A.4
  • 51
    • 78751646831 scopus 로고    scopus 로고
    • Probes for studying cholesterol binding and cell biology
    • Gimpl, G., and Gehrig-Burger, K. (2011) Probes for studying cholesterol binding and cell biology. Steroids 76, 216-231
    • (2011) Steroids , vol.76 , pp. 216-231
    • Gimpl, G.1    Gehrig-Burger, K.2
  • 52
    • 61949446361 scopus 로고    scopus 로고
    • Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells
    • Mondal, M., Mesmin, B., Mukherjee, S., and Maxfield, F. R. (2009) Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells. Mol. Biol. Cell 20, 581-588
    • (2009) Mol. Biol. Cell , vol.20 , pp. 581-588
    • Mondal, M.1    Mesmin, B.2    Mukherjee, S.3    Maxfield, F.R.4
  • 53
    • 84863829102 scopus 로고    scopus 로고
    • A dual polybasic motif determines phosphoinositide binding and regulation in the P2X channel family
    • Bernier, L. P., Blais, D., Boué-Grabot, É., and Séguéla, P. (2012) A dual polybasic motif determines phosphoinositide binding and regulation in the P2X channel family. PLoS One 7, e40595
    • (2012) PLoS One , vol.7 , pp. e40595
    • Bernier, L.P.1    Blais, D.2    Boué-Grabot É.3    Séguéla, P.4
  • 54
    • 35348909573 scopus 로고    scopus 로고
    • Agonist potency at P2X7 receptors is modulated by structurally diverse lipids
    • Michel, A. D., and Fonfria, E. (2007) Agonist potency at P2X7 receptors is modulated by structurally diverse lipids. Br. J. Pharmacol. 152, 523-537
    • (2007) Br. J. Pharmacol. , vol.152 , pp. 523-537
    • Michel, A.D.1    Fonfria, E.2
  • 55
    • 84860785529 scopus 로고    scopus 로고
    • Molecular mechanism of ATP binding and ion channel activation in P2X receptors
    • Hattori, M., and Gouaux, E. (2012) Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature 485, 207-212
    • (2012) Nature , vol.485 , pp. 207-212
    • Hattori, M.1    Gouaux, E.2
  • 56
    • 34547135165 scopus 로고    scopus 로고
    • Potential roles of membrane fluidity and ceramide in hyperthermia and alcohol stimulation of TRAIL apoptosis
    • Moulin, M., Carpentier, S., Levade, T., and Arrigo, A. P. (2007) Potential roles of membrane fluidity and ceramide in hyperthermia and alcohol stimulation of TRAIL apoptosis. Apoptosis 12, 1703-1720
    • (2007) Apoptosis , vol.12 , pp. 1703-1720
    • Moulin, M.1    Carpentier, S.2    Levade, T.3    Arrigo, A.P.4
  • 57
    • 84868193217 scopus 로고    scopus 로고
    • Innate immunosenescence: Effect of aging on cells and receptors of the innate immune system in humans
    • Solana, R., Tarazona, R., Gayoso, I., Lesur, O., Dupuis, G., and Fulop, T. (2012) Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans. Semin. Immunol. 24, 331-341
    • (2013) Semin. Immunol. , vol.24 , pp. 331-341
    • Solana, R.1    Tarazona, R.2    Gayoso, I.3    Lesur, O.4    Dupuis, G.5    Fulop, T.6
  • 58
    • 80054037447 scopus 로고    scopus 로고
    • Plasma membrane cholesterol plays a critical role in the Salmonella-induced anti-inflammatory response in intestinal epithelial cells
    • Huang, F. C. (2011) Plasma membrane cholesterol plays a critical role in the Salmonella-induced anti-inflammatory response in intestinal epithelial cells. Cell. Immunol. 271, 480-487
    • (2011) Cell. Immunol. , vol.271 , pp. 480-487
    • Huang, F.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.