Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 8, 2012, Pages

  Bowie, Rachel V ^a   Donatello, Simona ^a   Lyes, Clíona ^a   Owens, Mark B ^a   Babina, Irina S ^a   Hudson, Lance ^a   Walsh, Shaun V ^b   O'Donoghue, Diarmuid P ^c   Amu, Sylvie ^d   Barry, Sean P ^d   Fallon, Padraic G ^d   Hopkins, Ann M ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b NINEWELLS HOSPITAL   (United Kingdom)

^c ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^d ST JAMES S HOSPITAL   (Ireland)

Author keywords

Adhesion; Barrier function; Colitis; Epithelium; Tight junction

Indexed keywords

ALKALINE PHOSPHATASE; FLOTILLIN 1; GAMMA INTERFERON; METHYL BETA CYCLODEXTRIN; OCCLUDIN; PROTEIN ZO1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; ILEUM; INTESTINE BIOPSY; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA PERMEABILITY; LIPID RAFT; MALE; MICROENVIRONMENT; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TIGHT JUNCTION; ULCERATIVE COLITIS; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BIOPSY; BLOTTING, WESTERN; CACO-2 CELLS; CENTRIFUGATION, DENSITY GRADIENT; COLITIS, ULCERATIVE; DIET; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENTERITIS; FEMALE; HUMANS; INTERLEUKIN-10; INTESTINAL MUCOSA; INTESTINES; LIPID METABOLISM; MALE; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MIDDLE AGED; PERMEABILITY; TIGHT JUNCTIONS;

EID: 84859775839     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00002.2011     Document Type: Article

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