Effect of S-methylisothiourea, an inducible nitric oxide synthase inhibitor, in joint pain and pathology in surgically induced model of osteoarthritis

Connective Tissue Research

Volumn 55, Issue 5-6, 2014, Pages 367-377

  Balaganur, Venkanna ^a   Pathak, Nitya Nand ^a   Lingaraju, Madhu C ^a   More, Amar Sunil ^a   Latief, Najeeb ^a   Kumari, Rashmi Rekha ^a   Kumar, Dinesh ^a   Tandan, Surendra K ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Anterior cruciate ligament transection; Mechanical hyperalgesia; Osteoarthritis; S methylisothiourea; Thermal hyperalgesia

Indexed keywords

ANALGESIC AGENT; COLLAGEN; ETORICOXIB; GLYCOSAMINOGLYCAN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; S METHYLISOTHIOUREA; THIOUREA DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; S-METHYLISOTHIOPSEUDOURONIUM;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR CRUCIATE LIGAMENT INJURY; ANTERIOR CRUCIATE LIGAMENT TRANSECTION; ARTHRALGIA; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE INJURY; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG EFFECT; ENZYME INHIBITION; HISTOPATHOLOGY; HYPERALGESIA; IN VIVO STUDY; KNEE FUNCTION; KNEE OSTEOARTHRITIS; MALE; MECHANICAL HYPERALGESIA; MENISCECTOMY; NONHUMAN; PAIN SEVERITY; PATHOPHYSIOLOGY; POSTOPERATIVE CARE; RAT; TAIL FLICK TEST; THERMAL HYPERALGESIA; ANALOGS AND DERIVATIVES; ANALYSIS OF VARIANCE; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTERIOR CRUCIATE LIGAMENT; BLOOD; COMPLICATION; HISTOLOGY; KNEE MENISCUS; OSTEOARTHRITIS; PATHOLOGY; SURGERY; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; ANTERIOR CRUCIATE LIGAMENT; ARTHRALGIA; HISTOLOGICAL TECHNIQUES; HYPERALGESIA; INTERLEUKIN-1BETA; ISOTHIURONIUM; MALE; MENISCI, TIBIAL; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; OSTEOARTHRITIS; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84911019515     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.3109/03008207.2014.953629     Document Type: Article

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