메뉴 건너뛰기




Volumn 103, Issue 4, 2013, Pages 764-772

Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: Implication for osteoarthritis therapy

Author keywords

iNOS; Monosodium iodoacetate; Osteoarthritis; Pain; S methylisothiourea

Indexed keywords

ANTIRHEUMATIC AGENT; ETORICOXIB; INDUCIBLE NITRIC OXIDE SYNTHASE; IODOACETIC ACID; NITRIC OXIDE SYNTHASE INHIBITOR; S METHYLPSEUDOTHIOUREA; UNCLASSIFIED DRUG;

EID: 84873339951     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2012.12.013     Document Type: Article
Times cited : (33)

References (58)
  • 1
    • 3242688055 scopus 로고    scopus 로고
    • Inflammation in osteoarthritis
    • S.B. Abramson Inflammation in osteoarthritis J Rheumatol 70 2004 70 76
    • (2004) J Rheumatol , vol.70 , pp. 70-76
    • Abramson, S.B.1
  • 2
    • 54249104477 scopus 로고    scopus 로고
    • Nitric oxide in inflammation and pain associated with osteoarthritis
    • S.B. Abramson Nitric oxide in inflammation and pain associated with osteoarthritis Arthritis Res Ther 10 2008 1 7
    • (2008) Arthritis Res Ther , vol.10 , pp. 1-7
    • Abramson, S.B.1
  • 3
    • 66149180583 scopus 로고    scopus 로고
    • Developments in the scientific understanding of osteoarthritis
    • S. Abramson, and M. Attur Developments in the scientific understanding of osteoarthritis Arthritis Res Ther 11 2009 227
    • (2009) Arthritis Res Ther , vol.11 , pp. 227
    • Abramson, S.1    Attur, M.2
  • 4
    • 0035656866 scopus 로고    scopus 로고
    • Nitric oxide and inflammatory mediators in the perpetuation of osteoarthritis
    • S.B. Abramson, M. Attur, A.R. Amin, and R. Clancy Nitric oxide and inflammatory mediators in the perpetuation of osteoarthritis Curr Rheumatol Rep 3 2001 535 541
    • (2001) Curr Rheumatol Rep , vol.3 , pp. 535-541
    • Abramson, S.B.1    Attur, M.2    Amin, A.R.3    Clancy, R.4
  • 5
    • 0030076587 scopus 로고    scopus 로고
    • A selective inhibitor of inducible nitric oxide synthase prolongs survival in a rat model of bacterial peritonitis: Comparison with two nonselective strategies
    • J.S. Aranow, J. Zhuang, H. Wang, V. Larkin, M. Smith, and M.P. Fink A selective inhibitor of inducible nitric oxide synthase prolongs survival in a rat model of bacterial peritonitis: comparison with two nonselective strategies Shock 5 1996 116 121
    • (1996) Shock , vol.5 , pp. 116-121
    • Aranow, J.S.1    Zhuang, J.2    Wang, H.3    Larkin, V.4    Smith, M.5    Fink, M.P.6
  • 6
    • 0025274640 scopus 로고
    • Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis
    • W.P. Arend, and J.M. Dayer Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis Arthritis Rheum 33 1990 305 315
    • (1990) Arthritis Rheum , vol.33 , pp. 305-315
    • Arend, W.P.1    Dayer, J.M.2
  • 7
    • 0029797733 scopus 로고    scopus 로고
    • Selective inhibition of the inducible isoform of nitric oxide synthase prevents pulmonary transvascular flux during acute endotoxemia
    • M.S. Arkovitz, J.R. Wispe, V.F. Garcia, and C. Szabo Selective inhibition of the inducible isoform of nitric oxide synthase prevents pulmonary transvascular flux during acute endotoxemia J Pediatr Surg 31 1996 1009 1015
    • (1996) J Pediatr Surg , vol.31 , pp. 1009-1015
    • Arkovitz, M.S.1    Wispe, J.R.2    Garcia, V.F.3    Szabo, C.4
  • 8
    • 33847410500 scopus 로고    scopus 로고
    • Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain
    • B. Beyreuther, N. Callizot, and T. Stohr Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain Arthritis Res Ther 9 2007 R14
    • (2007) Arthritis Res Ther , vol.9 , pp. 14
    • Beyreuther, B.1    Callizot, N.2    Stohr, T.3
  • 9
    • 0036822533 scopus 로고    scopus 로고
    • The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide
    • C. Boileau, J. Martel-Pelletier, F. Moldovan, J.Y. Jouzeau, P. Netter, and P.T. Manning The in situ up-regulation of chondrocyte interleukin-1- converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide Arthritis Rheum 46 2002 2637 2647
    • (2002) Arthritis Rheum , vol.46 , pp. 2637-2647
    • Boileau, C.1    Martel-Pelletier, J.2    Moldovan, F.3    Jouzeau, J.Y.4    Netter, P.5    Manning, P.T.6
  • 11
    • 0242606943 scopus 로고    scopus 로고
    • Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis
    • S.E. Bove, S.L. Calcaterra, R.M. Brooker, C.M. Huber, R.E. Guzman, and P.L. Juneau Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis Osteoarthr Cartil 11 2003 821 830
    • (2003) Osteoarthr Cartil , vol.11 , pp. 821-830
    • Bove, S.E.1    Calcaterra, S.L.2    Brooker, R.M.3    Huber, C.M.4    Guzman, R.E.5    Juneau, P.L.6
  • 12
    • 33745614887 scopus 로고    scopus 로고
    • A quantitative approach to measure joint pain in experimental osteoarthritis - Evidence of a role for nitric oxide
    • R.R. Castro, F.Q. Cunha, F.S. Silva Jr., and F.A. Rocha A quantitative approach to measure joint pain in experimental osteoarthritis - evidence of a role for nitric oxide Osteoarthr Cartil 8 2006 769 776
    • (2006) Osteoarthr Cartil , vol.8 , pp. 769-776
    • Castro, R.R.1    Cunha, F.Q.2    Silva, Jr.F.S.3    Rocha, F.A.4
  • 13
    • 0027477465 scopus 로고
    • Contribution of central neuroplasticity to pathological pain: Review of clinical and experimental evidence
    • T.J. Coderre, J. Katz, A.L. Vaccarino, and R. Melzack Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence Pain 52 1993 259 285
    • (1993) Pain , vol.52 , pp. 259-285
    • Coderre, T.J.1    Katz, J.2    Vaccarino, A.L.3    Melzack, R.4
  • 14
    • 5644231065 scopus 로고    scopus 로고
    • The monosodium iodoacetate model of osteoarthritis: A model of chronic nociceptive pain in rats?
    • R. Combe, S. Bramwell, and M.J. Field The monosodium iodoacetate model of osteoarthritis: a model of chronic nociceptive pain in rats? Neurosci Lett 370 2004 236 240
    • (2004) Neurosci Lett , vol.370 , pp. 236-240
    • Combe, R.1    Bramwell, S.2    Field, M.J.3
  • 15
    • 78650107700 scopus 로고    scopus 로고
    • Interpreting joint pain: Quantitative sensory testing in musculoskeletal management
    • C.A. Courtney, A.E. Kavchak, C.D. Lowry, and M.A. O'Hearn Interpreting joint pain: quantitative sensory testing in musculoskeletal management J Orthop Sports Phys Ther 40 2010 818 825
    • (2010) J Orthop Sports Phys Ther , vol.40 , pp. 818-825
    • Courtney, C.A.1    Kavchak, A.E.2    Lowry, C.D.3    O'Hearn, M.A.4
  • 16
    • 11144240791 scopus 로고    scopus 로고
    • Characterization of a method for measuring primary hyperalgesia of deep somatic tissue
    • A.S. David, R. Rajan, and A.S. Kathleen Characterization of a method for measuring primary hyperalgesia of deep somatic tissue J Pain 6 2005 41 47
    • (2005) J Pain , vol.6 , pp. 41-47
    • David, A.S.1    Rajan, R.2    Kathleen, A.S.3
  • 17
    • 0026467074 scopus 로고
    • Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases
    • A.J. Farrell, D.R. Blake, R.M. Palmer, and S. Moncada Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases Ann Rheum Dis 51 1992 1219 1522
    • (1992) Ann Rheum Dis , vol.51 , pp. 1219-1522
    • Farrell, A.J.1    Blake, D.R.2    Palmer, R.M.3    Moncada, S.4
  • 18
    • 33344467770 scopus 로고    scopus 로고
    • Clinical practice. Osteoarthritis of knee
    • D.T. Felson Clinical practice. Osteoarthritis of knee N Engl J Med 354 2006 841 848
    • (2006) N Engl J Med , vol.354 , pp. 841-848
    • Felson, D.T.1
  • 19
    • 78650173659 scopus 로고    scopus 로고
    • Gait analysis and pain response of two rodent models of osteoarthritis
    • C.E. Ferland, S. Laverty, F. Beaudry, and P. Vachon Gait analysis and pain response of two rodent models of osteoarthritis Pharmacol Biochem Behav 97 2011 603 610
    • (2011) Pharmacol Biochem Behav , vol.97 , pp. 603-610
    • Ferland, C.E.1    Laverty, S.2    Beaudry, F.3    Vachon, P.4
  • 20
    • 0023810797 scopus 로고
    • A novel method for the sampling of synovial fluid in mice: Assay of a synovial lysosomal enzyme in zymosan induced arthritis
    • F. Folliard, and B. Terlain A novel method for the sampling of synovial fluid in mice: assay of a synovial lysosomal enzyme in zymosan induced arthritis Agents Actions 25 1988 139 145
    • (1988) Agents Actions , vol.25 , pp. 139-145
    • Folliard, F.1    Terlain, B.2
  • 21
    • 0030881805 scopus 로고    scopus 로고
    • Mono-iodoacetate-induced experimental osteoarthritis. A dose-response study of loss of mobility, morphology, and biochemistry
    • C. Guingamp, P. Gegout-Pottie, L. Philippe, B. Terlain, P. Netter, and P. Gillet Mono-iodoacetate-induced experimental osteoarthritis. A dose-response study of loss of mobility, morphology, and biochemistry Arthritis Rheum 40 1997 1670 1679
    • (1997) Arthritis Rheum , vol.40 , pp. 1670-1679
    • Guingamp, C.1    Gegout-Pottie, P.2    Philippe, L.3    Terlain, B.4    Netter, P.5    Gillet, P.6
  • 22
    • 0242552331 scopus 로고    scopus 로고
    • Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: An animal model of osteoarthritis
    • R.E. Guzman, M.G. Evans, S. Bove, B. Morenko, and K. Kilgore Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis Toxicol Pathol 31 2003 619 624
    • (2003) Toxicol Pathol , vol.31 , pp. 619-624
    • Guzman, R.E.1    Evans, M.G.2    Bove, S.3    Morenko, B.4    Kilgore, K.5
  • 23
    • 42449155118 scopus 로고    scopus 로고
    • Modulation of pain in osteoarthritis: The role of nitric oxide
    • C.M. Hancock, and C. Riegger-Krugh Modulation of pain in osteoarthritis: the role of nitric oxide Clin J Pain 24 2008 353 365
    • (2008) Clin J Pain , vol.24 , pp. 353-365
    • Hancock, C.M.1    Riegger-Krugh, C.2
  • 24
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • K. Hargreaves, R. Dubner, F. Brown, C. Flores, and J. Joris A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia Pain 32 1988 77 88
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 25
    • 65649131953 scopus 로고    scopus 로고
    • Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice
    • V.L. Harvey, and A.H. Dickenson Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice Mol Pain 5 2009 18
    • (2009) Mol Pain , vol.5 , pp. 18
    • Harvey, V.L.1    Dickenson, A.H.2
  • 27
    • 78650986866 scopus 로고    scopus 로고
    • Pharmacologic therapy for osteoarthritis - The era of disease modification
    • D.J. Hunter Pharmacologic therapy for osteoarthritis - the era of disease modification Nat Rev Rheumatol 7 2011 13 22
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 13-22
    • Hunter, D.J.1
  • 28
    • 77957685729 scopus 로고    scopus 로고
    • Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model
    • H.J. Im, J.S. Kim, X. Li, N. Kotwal, D.R. Sumner, and A.J. van Wijnen Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model Arthritis Rheum 62 2010 2995 3005
    • (2010) Arthritis Rheum , vol.62 , pp. 2995-3005
    • Im, H.J.1    Kim, J.S.2    Li, X.3    Kotwal, N.4    Sumner, D.R.5    Van Wijnen, A.J.6
  • 29
    • 33947178518 scopus 로고    scopus 로고
    • Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: Increased expression of ATF-3 and pharmacological characterisation
    • S.P. Ivanavicius, A.D. Ball, C.G. Heapy, F.R. Westwood, and F. Murray Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation Pain 128 2007 272 282
    • (2007) Pain , vol.128 , pp. 272-282
    • Ivanavicius, S.P.1    Ball, A.D.2    Heapy, C.G.3    Westwood, F.R.4    Murray, F.5
  • 32
    • 33845871512 scopus 로고    scopus 로고
    • Inflammation-induced reduction of spontaneous activity by adjuvant: A novel model to study the effect of analgesics in rats
    • D.J. Matson, D.C. Broom, S.R. Carson, J. Baldassari, J. Kehne, and D.N. Cortright Inflammation-induced reduction of spontaneous activity by adjuvant: a novel model to study the effect of analgesics in rats J Pharmacol Exp Ther 320 2007 194 201
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 194-201
    • Matson, D.J.1    Broom, D.C.2    Carson, S.R.3    Baldassari, J.4    Kehne, J.5    Cortright, D.N.6
  • 33
    • 84858684172 scopus 로고    scopus 로고
    • Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis
    • Matthew Thakur, Wahida Rahman, Carl Hobbs, Anthony H. Dickenson, and David L.H. Bennett Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis PLoS One 7 2012 33730
    • (2012) PLoS One , vol.7 , pp. 33730
    • Thakur, M.1    Rahman, W.2    Hobbs, C.3    Dickenson, A.H.4    Bennett, D.L.H.5
  • 34
    • 0033103354 scopus 로고    scopus 로고
    • Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its down regulation by axotomy
    • G.J. Michael, and J.V. Priestley Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its down regulation by axotomy J Neurosci 19 1999 1844 1854
    • (1999) J Neurosci , vol.19 , pp. 1844-1854
    • Michael, G.J.1    Priestley, J.V.2
  • 36
    • 0029954092 scopus 로고    scopus 로고
    • Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons
    • S. Neumann, T.P. Doubell, T. Leslie, and C.J. Woolf Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons Nature 384 1996 360 364
    • (1996) Nature , vol.384 , pp. 360-364
    • Neumann, S.1    Doubell, T.P.2    Leslie, T.3    Woolf, C.J.4
  • 37
    • 0032520767 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase prevents lps-induced acute lung injury in dogs
    • M. Numata, S. Shunsuke, M. Naoki, M. Akira, N. Yoji, and I. Satoshi Inhibition of inducible nitric oxide synthase prevents lps-induced acute lung injury in dogs J Immunol 160 1998 3031 3037
    • (1998) J Immunol , vol.160 , pp. 3031-3037
    • Numata, M.1    Shunsuke, S.2    Naoki, M.3    Akira, M.4    Yoji, N.5    Satoshi, I.6
  • 38
    • 77953289025 scopus 로고    scopus 로고
    • Cartilage degeneration is associated with augmented chemically-induced joint pain in rats
    • M. Okamoto, and Y. Atsuta Cartilage degeneration is associated with augmented chemically-induced joint pain in rats Clin Orthop Relat Res 468 2010 1423 1427
    • (2010) Clin Orthop Relat Res , vol.468 , pp. 1423-1427
    • Okamoto, M.1    Atsuta, Y.2
  • 39
    • 84858701980 scopus 로고    scopus 로고
    • Afferent drive elicits ongoing pain in a model of advanced osteoarthritis
    • A. Okun, P. Liu, P. Davis, J. Ren, B. Remeniuk, and T. Brion Afferent drive elicits ongoing pain in a model of advanced osteoarthritis Pain 153 2012 924 933
    • (2012) Pain , vol.153 , pp. 924-933
    • Okun, A.1    Liu, P.2    Davis, P.3    Ren, J.4    Remeniuk, B.5    Brion, T.6
  • 40
    • 30744441822 scopus 로고    scopus 로고
    • Calibrated forceps: A sensitive and reliable tool for pain and analgesia studies
    • E.L. Oliva, B. Michel, R. Jean-Luc, S. Gregory, B. Malika, and P. Pierrick Calibrated forceps: a sensitive and reliable tool for pain and analgesia studies J Pain 7 2006 32 39
    • (2006) J Pain , vol.7 , pp. 32-39
    • Oliva, E.L.1    Michel, B.2    Jean-Luc, R.3    Gregory, S.4    Malika, B.5    Pierrick, P.6
  • 41
    • 0033166769 scopus 로고    scopus 로고
    • Reduction in the structural changes of experimental osteoarthritis by a nitric oxide inhibitor
    • J. Pelletier, D. Jovanovic, and J.C. Fernandes Reduction in the structural changes of experimental osteoarthritis by a nitric oxide inhibitor Osteoarthr Cartil 7 1999 416 418
    • (1999) Osteoarthr Cartil , vol.7 , pp. 416-418
    • Pelletier, J.1    Jovanovic, D.2    Fernandes, J.C.3
  • 42
    • 0036591439 scopus 로고    scopus 로고
    • Neuroplasticity - An important factor in acute and chronic pain
    • S. Petersen-Felix, and M. Curatolo Neuroplasticity - an important factor in acute and chronic pain Swiss Med Wkly 132 2002 273 278
    • (2002) Swiss Med Wkly , vol.132 , pp. 273-278
    • Petersen-Felix, S.1    Curatolo, M.2
  • 43
    • 31844455533 scopus 로고    scopus 로고
    • Administration of baclofen a gamma-aminobutyric acid type B agonist in the thalamic ventrobasal complex, attenuates allodynia in monoarthritic rats subjected to the ankle-bend test
    • C.S. Potes, F.L. Neto, and J.M. Castro-Lopes Administration of baclofen a gamma-aminobutyric acid type B agonist in the thalamic ventrobasal complex, attenuates allodynia in monoarthritic rats subjected to the ankle-bend test J Neurosci Res 83 2006 515 523
    • (2006) J Neurosci Res , vol.83 , pp. 515-523
    • Potes, C.S.1    Neto, F.L.2    Castro-Lopes, J.M.3
  • 44
    • 68649093976 scopus 로고    scopus 로고
    • Increased gene expression and production of spinal cyclooxygenase 1 and 2 during experimental osteoarthritis pain
    • M. Procházková, P. Zanvit, T. Doležal, L. Prokešová, and M. Kršiak Increased gene expression and production of spinal cyclooxygenase 1 and 2 during experimental osteoarthritis pain Physiol Res 2012 58 2009 419 425
    • (2009) Physiol Res , vol.2012 , Issue.58 , pp. 419-425
    • Procházková, M.1    Zanvit, P.2    Doležal, T.3    Prokešová, L.4    Kršiak, M.5
  • 45
    • 0000382556 scopus 로고
    • A method for measurement of analgesic activity of inflamed tissue
    • L.O. Randall, and J. Sellito A method for measurement of analgesic activity of inflamed tissue Arch Int Pharmacodyn 111 1957 209 219
    • (1957) Arch Int Pharmacodyn , vol.111 , pp. 209-219
    • Randall, L.O.1    Sellito, J.2
  • 46
    • 0036629201 scopus 로고    scopus 로고
    • Spectrophotometric determination of serum nitrite and nitrate by copper-cadmium alloy
    • K.V.H. Sastry, R.P. Moudgal, J. Mohan, J.S. Tyagi, and G.S. Rao Spectrophotometric determination of serum nitrite and nitrate by copper-cadmium alloy Analyt Biochem 306 2002 79 82
    • (2002) Analyt Biochem , vol.306 , pp. 79-82
    • Sastry, K.V.H.1    Moudgal, R.P.2    Mohan, J.3    Tyagi, J.S.4    Rao, G.S.5
  • 47
    • 0034766887 scopus 로고    scopus 로고
    • Nitric oxide prevents the IFN-gamma/LPS-induced hepatotoxicity in a protein kinase G-independent manner
    • H.S. So, B.H. Jung, H.S. Song, K. Myung, J.S. Park, and K.M. Chae Nitric oxide prevents the IFN-gamma/LPS-induced hepatotoxicity in a protein kinase G-independent manner Immunopharmacol Immunotoxicol 23 2001 321 334
    • (2001) Immunopharmacol Immunotoxicol , vol.23 , pp. 321-334
    • So, H.S.1    Jung, B.H.2    Song, H.S.3    Myung, K.4    Park, J.S.5    Chae, K.M.6
  • 48
    • 5644302490 scopus 로고    scopus 로고
    • A robust model of adjuvant-induced chronic unilateral arthritis in two mouse strains
    • D.G. Stephan, S.M. Daniel, J.C. Christopher, and P.C. Iain A robust model of adjuvant-induced chronic unilateral arthritis in two mouse strains J Neurosci Methods 139 2004 281 291
    • (2004) J Neurosci Methods , vol.139 , pp. 281-291
    • Stephan, D.G.1    Daniel, S.M.2    Christopher, J.C.3    Iain, P.C.4
  • 49
    • 7744237924 scopus 로고    scopus 로고
    • Nitric oxide decreases IGF-1 receptor function in vitro; Glutathione depletion enhances this effect in vivo
    • R.K. Studer Nitric oxide decreases IGF-1 receptor function in vitro; glutathione depletion enhances this effect in vivo Osteoarthritis Cartilage 12 2004 863 869
    • (2004) Osteoarthritis Cartilage , vol.12 , pp. 863-869
    • Studer, R.K.1
  • 51
    • 0028577721 scopus 로고
    • Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase
    • C. Szabo, G.J. Southan, and C. Thiemerrnann Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase Proc Natl Acad Sci U S A 91 1994 12472 12476
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 12472-12476
    • Szabo, C.1    Southan, G.J.2    Thiemerrnann, C.3
  • 53
    • 34547116227 scopus 로고    scopus 로고
    • Evaluation of pain behavior and bone destruction in two arthritic models in guinea pig and rat
    • H. Vermeirsch, R. Biermans, P.L. Salmon, and T.F. Meert Evaluation of pain behavior and bone destruction in two arthritic models in guinea pig and rat Pharmacol Biochem Behav 87 2007 349 359
    • (2007) Pharmacol Biochem Behav , vol.87 , pp. 349-359
    • Vermeirsch, H.1    Biermans, R.2    Salmon, P.L.3    Meert, T.F.4
  • 54
    • 0034782634 scopus 로고    scopus 로고
    • Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage
    • K. Vuolteenaho, T. Moilanen, N. Al Saffar, R.G. Knowles, and E. Moilanen Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage Osteoarthr Cartil 9 2001 597 605
    • (2001) Osteoarthr Cartil , vol.9 , pp. 597-605
    • Vuolteenaho, K.1    Moilanen, T.2    Al Saffar, N.3    Knowles, R.G.4    Moilanen, E.5
  • 57
    • 0034625770 scopus 로고    scopus 로고
    • Neuronal plasticity: Increasing the gain in pain
    • C.J. Woolf, and M.W. Salter Neuronal plasticity: increasing the gain in pain Science 288 2000 1765 1769
    • (2000) Science , vol.288 , pp. 1765-1769
    • Woolf, C.J.1    Salter, M.W.2
  • 58
    • 0037196896 scopus 로고    scopus 로고
    • Two variables that can be used as pain indices in experimental animal models of arthritis
    • C.Y. Yun, T.K. Sung, H.K. Chang, L. Yeoungsu, J.G. James, and M.C. Jin Two variables that can be used as pain indices in experimental animal models of arthritis J Neurosci Methods 115 2002 107 113
    • (2002) J Neurosci Methods , vol.115 , pp. 107-113
    • Yun, C.Y.1    Sung, T.K.2    Chang, H.K.3    Yeoungsu, L.4    James, J.G.5    Jin, M.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.