Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease

Acta Neuropathologica Communications

Volumn 2, Issue 1, 2014, Pages

  Végh, Marlene J ^a   Heldring, Céline M ^a   Kamphuis, Willem ^b   Hijazi, Sara ^a   Timmerman, Arie J ^a   Li, Ka Wan ^a   van Nierop, Pim ^a   Mansvelder, Huibert D ^a   Hol, Elly M ^c   Smit, August B ^a   van Kesteren, Ronald E ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Alzheimer's disease; Extracellular matrix; Hippocampus; Memory; Perineuronal net; Plasticity

Indexed keywords

CHONDROITIN ABC LYASE; SCLEROPROTEIN;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL; C57BL MOUSE; CONDITIONING; DISEASE MODEL; DRUG EFFECTS; EXTRACELLULAR MATRIX; HIPPOCAMPUS; HUMAN; LONG TERM POTENTIATION; MALE; MEMORY DISORDER; METABOLISM; MOUSE; PATHOLOGY; PROTEOMICS; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; CHONDROITIN ABC LYASE; CONDITIONING (PSYCHOLOGY); DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; HIPPOCAMPUS; HUMANS; LONG-TERM POTENTIATION; MALE; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PLAQUE, AMYLOID; PROTEOMICS;

EID: 84910641125     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-014-0076-z     Document Type: Article

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