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Volumn 346, Issue 6211, 2014, Pages

Genomically encoded analog memory with precise in vivo dna writing in living cell populations

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; RECOMBINASE; SINGLE STRANDED DNA;

EID: 84910594404     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1256272     Document Type: Article
Times cited : (224)

References (51)
  • 1
    • 84874683719 scopus 로고    scopus 로고
    • Towards practical, high-capacity, low-maintenance information storage in synthesized DNA
    • pmid: 23354052
    • N. Goldman et al., Towards practical, high-capacity, low-maintenance information storage in synthesized DNA. Nature 494, 77-80 (2013). doi: 10.1038/nature11875; pmid: 23354052
    • (2013) Nature , vol.494 , pp. 77-80
    • Goldman, N.1
  • 2
    • 84866747149 scopus 로고    scopus 로고
    • Next-generation digital information storage in DNA
    • pmid: 22903519
    • G. M. Church, Y. Gao, S. Kosuri, Next-generation digital information storage in DNA. Science 337, 1628 (2012). doi: 10.1126/science.1226355; pmid: 22903519
    • (2012) Science , vol.337 , pp. 1628
    • Church, G.M.1    Gao, Y.2    Kosuri, S.3
  • 3
    • 84883820704 scopus 로고    scopus 로고
    • Building synthetic memory
    • pmid: 24028965
    • M. C. Inniss, P. A. Silver, Building synthetic memory. Curr. Biol. 23, R812-R816 (2013). doi: 10.1016/j.cub.2013.06.047; pmid: 24028965
    • (2013) Curr. Biol. , vol.23 , pp. R812-R816
    • Inniss, M.C.1    Silver, P.A.2
  • 4
    • 0034688174 scopus 로고    scopus 로고
    • Construction of a genetic toggle switch in Escherichia coli
    • pmid: 10659857
    • T. S. Gardner, C. R. Cantor, J. J. Collins, Construction of a genetic toggle switch in Escherichia coli. Nature 403, 339-342 (2000). doi: 10.1038/35002131; pmid: 10659857
    • (2000) Nature , vol.403 , pp. 339-342
    • Gardner, T.S.1    Cantor, C.R.2    Collins, J.J.3
  • 5
    • 84897482912 scopus 로고    scopus 로고
    • Programmable bacteria detect and record an environmental signal in the mammalian gut
    • pmid: 24639514
    • J. W. Kotula et al., Programmable bacteria detect and record an environmental signal in the mammalian gut. Proc. Natl. Acad. Sci. U.S.A. 111, 4838-4843 (2014). doi: 10.1073/ pnas.1321321111; pmid: 24639514
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 4838-4843
    • Kotula, J.W.1
  • 6
    • 84863644753 scopus 로고    scopus 로고
    • Synthetic memory circuits for tracking human cell fate
    • pmid: 22751502
    • D. R. Burrill, M. C. Inniss, P. M. Boyle, P. A. Silver, Synthetic memory circuits for tracking human cell fate. Genes Dev. 26, 1486-1497 (2012). doi: 10.1101/gad.189035.112; pmid: 22751502
    • (2012) Genes Dev. , vol.26 , pp. 1486-1497
    • Burrill, D.R.1    Inniss, M.C.2    Boyle, P.M.3    Silver, P.A.4
  • 7
    • 3042822415 scopus 로고    scopus 로고
    • An engineered epigenetic transgene switch in mammalian cells
    • pmid: 15184906
    • B. P. Kramer et al., An engineered epigenetic transgene switch in mammalian cells. Nat. Biotechnoi. 22, 867-870 (2004). doi: 10.1038/nbt980; pmid: 15184906
    • (2004) Nat. Biotechnoi. , vol.22 , pp. 867-870
    • Kramer, B.P.1
  • 8
    • 34548856538 scopus 로고    scopus 로고
    • Rational design of memory in eukaryotic cells
    • pmid: 17875664
    • C. M. Ajo-Franklin et al., Rational design of memory in eukaryotic cells. Genes Dev. 21, 2271-2276 (2007). doi: 10.1101/gad.1586107; pmid: 17875664
    • (2007) Genes Dev. , vol.21 , pp. 2271-2276
    • Ajo-Franklin, C.M.1
  • 9
    • 84875230351 scopus 로고    scopus 로고
    • Synthetic circuits integrating logic and memory in living cells
    • pmid: 23396014
    • P. Siuti, J. Yazbek, T. K. Lu, Synthetic circuits integrating logic and memory in living cells. Nat. Biotechnoi. 31, 448-452 (2013). doi: 10.1038/nbt.2510; pmid: 23396014
    • (2013) Nat. Biotechnoi. , vol.31 , pp. 448-452
    • Siuti, P.1    Yazbek, J.2    Lu, T.K.3
  • 10
    • 84861865655 scopus 로고    scopus 로고
    • Rewritable digital data storage in live cells via engineered control of recombination directionality
    • pmid: 22615351
    • J. Bonnet, P. Subsoontorn, D. Endy, Rewritable digital data storage in live cells via engineered control of recombination directionality. Proc. Natl. Acad. Sci. U.S.A. 109, 8884-8889 (2012). doi: 10.1073/pnas.1202344109; pmid: 22615351
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 8884-8889
    • Bonnet, J.1    Subsoontorn, P.2    Endy, D.3
  • 11
    • 84877607428 scopus 로고    scopus 로고
    • Amplifying genetic logic gates
    • pmid: 23539178
    • J. Bonnet, P. Yin, M. E. Ortiz, P. Subsoontorn, D. Endy, Amplifying genetic logic gates. Science 340, 599-603 (2013). doi: 10.1126/science.1232758; pmid: 23539178
    • (2013) Science , vol.340 , pp. 599-603
    • Bonnet, J.1    Yin, P.2    Ortiz, M.E.3    Subsoontorn, P.4    Endy, D.5
  • 12
    • 66349125024 scopus 로고    scopus 로고
    • Synthetic gene networks that count
    • pmid: 19478183
    • A. E. Friedland et al., Synthetic gene networks that count. Science 324, 1199-1202 (2009). doi: 10.1126/science.1172005; pmid: 19478183
    • (2009) Science , vol.324 , pp. 1199-1202
    • Friedland, A.E.1
  • 13
    • 0035810938 scopus 로고    scopus 로고
    • High efficiency mutagenesis, repair, and engineering of chromosomal DNA using single-stranded oligonucleotides
    • pmid: 11381128
    • H. M. Ellis, D. Yu, T. DiTizio, D. L. Court, High efficiency mutagenesis, repair, and engineering of chromosomal DNA using single-stranded oligonucleotides. Proc. Natl. Acad. Sci. U.S.A. 98, 6742-6746 (2001). doi: 10.1073/ pnas.121164898; pmid: 11381128
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 6742-6746
    • Ellis, H.M.1    Yu, D.2    DiTizio, T.3    Court, D.L.4
  • 14
    • 0346103663 scopus 로고    scopus 로고
    • Enhanced levels of λ Red-mediated recombinants in mismatch repair mutants
    • pmid: 14673109
    • N. Costantino, D. L. Court, Enhanced levels of λ Red-mediated recombinants in mismatch repair mutants. Proc. Natl. Acad. Sci. U.S.A. 100, 15748-15753 (2003). doi: 10.1073/ pnas.24349591.00; pmid: 14673109
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 15748-15753
    • Costantino, N.1    Court, D.L.2
  • 15
    • 0034705144 scopus 로고    scopus 로고
    • An efficient recombination system for chromosome engineering in Escherichia coli
    • pmid: 10811905
    • D. Yu et al., An efficient recombination system for chromosome engineering in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 97, 5978-5983 (2000). doi: 10.1073/ pnas.100127597; pmid: 10811905
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 5978-5983
    • Yu, D.1
  • 16
    • 79952002951 scopus 로고    scopus 로고
    • Probing cellular processes with oligo-mediated recombination and using the knowledge gained to optimize recombineering
    • pmid: 21256136
    • J. A. Sawitzke et al., Probing cellular processes with oligo-mediated recombination and using the knowledge gained to optimize recombineering. J. Mol. Biol. 407, 45-59 (2011). doi: 10.1016/j.jmb.2011.01.030; pmid: 21256136
    • (2011) J. Mol. Biol. , vol.407 , pp. 45-59
    • Sawitzke, J.A.1
  • 17
    • 72949112229 scopus 로고    scopus 로고
    • Oligonucleotide recombination in Gramnegative bacteria
    • pmid: 19943907
    • B. Swingle et al., Oligonucleotide recombination in Gramnegative bacteria. Mol. Microbiol. 75, 138-148 (2010). doi: 10.1111/j.1365-2958.2009.06876.x; pmid: 19943907
    • (2010) Mol. Microbiol , vol.75 , pp. 138-148
    • Swingle, B.1
  • 18
    • 40349101854 scopus 로고    scopus 로고
    • Identification and analysis of recombineering functions from Gram-negative and Gram-positive bacteria and their phages
    • pmid: 18230724
    • S. Datta, N. Costantino, X. Zhou, D. L. Court, Identification and analysis of recombineering functions from Gram-negative and Gram-positive bacteria and their phages. Proc. Natl. Acad. Sci. U.S.A. 105, 1626-1631 (2008). doi: 10.1073/ pnas.0709089105; pmid: 18230724
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 1626-1631
    • Datta, S.1    Costantino, N.2    Zhou, X.3    Court, D.L.4
  • 19
    • 0021473220 scopus 로고
    • Multicopy single-stranded DNA isolated from a gram-negative bacterium, Myxococcus xanthus
    • pmid: 6088065
    • T. Yee, T. Furuichi, S. Inouye, M. Inouye, Multicopy single-stranded DNA isolated from a gram-negative bacterium, Myxococcus xanthus. Ceii 38, 203-209 (1984). doi: 10.1016/ 0092-8674(84)90541-5; pmid: 6088065
    • (1984) Ceii , vol.38 , pp. 203-209
    • Yee, T.1    Furuichi, T.2    Inouye, S.3    Inouye, M.4
  • 20
    • 23844509486 scopus 로고    scopus 로고
    • Retrons, msDNA, and the bacterial genome
    • pmid: 16093702
    • B. C. Lampson, M. Inouye, S. Inouye, Retrons, msDNA, and the bacterial genome. Cytogenet. Genome Res. 110, 491-499 (2005). doi: 10.1159/000084982; pmid: 16093702
    • (2005) Cytogenet. Genome Res. , vol.110 , pp. 491-499
    • Lampson, B.C.1    Inouye, M.2    Inouye, S.3
  • 21
    • 0024523256 scopus 로고
    • Reverse transcriptase-dependent synthesis of a covalently linked, branched DNA-RNA compound in E. Coli B
    • pmid: 2466573
    • D. Um, W. K. Maas, Reverse transcriptase-dependent synthesis of a covalently linked, branched DNA-RNA compound in E. coli B. Cell 56, 891-904 (1989). doi: 10.1016/0092-8674(89) 90693-4; pmid: 2466573
    • (1989) Cell , vol.56 , pp. 891-904
    • Um, D.1    Maas, W.K.2
  • 22
    • 0030861452 scopus 로고    scopus 로고
    • Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/l1-l2 regulatory elements
    • pmid: 9092630
    • 2 regulatory elements. Nucleic Acids Res. 25, 1203-1210 (1997). doi: 10.1093/nar/25.6.1203; pmid: 9092630
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1203-1210
    • Lutz, R.1    Bujard, H.2
  • 23
    • 27244447331 scopus 로고    scopus 로고
    • Retrovirus reverse transcriptases containing a modified YXDD motif
    • pmid: 16004080
    • P. L. Sharma, V. Nurpeisov, R. F. Schinazi, Retrovirus reverse transcriptases containing a modified YXDD motif. Antivir. Chem. Chemother. 16, 169-182 (2005).pmid: 16004080
    • (2005) Antivir. Chem. Chemother , vol.16 , pp. 169-182
    • Sharma, P.L.1    Nurpeisov, V.2    Schinazi, R.F.3
  • 24
    • 0029123850 scopus 로고
    • Gene regulation by antisense DNA produced in vivo
    • pmid: 7544343
    • J. R. Mao, M. Shimada, S. Inouye, M. Inouye, Gene regulation by antisense DNA produced in vivo. J. Biol. Chem. 270, 19684-19687 (1995). doi: 10.1074/jbc.270.34.19684; pmid: 7544343
    • (1995) J. Biol. Chem. , vol.270 , pp. 19684-19687
    • Mao, J.R.1    Shimada, M.2    Inouye, S.3    Inouye, M.4
  • 25
    • 26644453335 scopus 로고    scopus 로고
    • Simple and highly efficient BAG recombineering using galK selection
    • pmid: 15731329
    • S. Warming, N. Costantino, D. L. Court, N. A. Jenkins, N. G. Copeland, Simple and highly efficient BAG recombineering using galK selection. Nucleic Acids Res. 33, e36 (2005). doi: 10.1093/nar/gni035; pmid: 15731329
    • (2005) Nucleic Acids Res. , vol.33 , pp. e36
    • Warming, S.1    Costantino, N.2    Court, D.L.3    Jenkins, N.A.4    Copeland, N.G.5
  • 26
    • 84857371657 scopus 로고    scopus 로고
    • From dusk till dawn: One-plasmid systems for light-regulated gene expression
    • pmid: 22245580
    • R. Ohlendorf, R. R. Vidavski, A. Eldar, K. Moffat, A. Möglich, From dusk till dawn: One-plasmid systems for light-regulated gene expression. J. Moi. Biol. 416, 534-542 (2012). doi: 10.1016/j.jmb.2012.01.001; pmid: 22245580
    • (2012) J. Moi. Biol. , vol.416 , pp. 534-542
    • Ohlendorf, R.1    Vidavski, R.R.2    Eldar, A.3    Moffat, K.4    Möglich, A.5
  • 27
    • 33845614522 scopus 로고    scopus 로고
    • The involvement of replication in single stranded oligonucleotide-mediated gene repair
    • pmid: 17088285
    • M. S. Huen et al;., The involvement of replication in single stranded oligonucleotide-mediated gene repair. Nucleic Acids Res. 34, 6183-6194 (2006). doi: 10.1093/nar/gkl852; pmid: 17088285
    • (2006) Nucleic Acids Res. , vol.34 , pp. 6183-6194
    • Huen, M.S.1
  • 28
    • 40549083336 scopus 로고    scopus 로고
    • Involvement of DNA replication in phage lambda Red-mediated homologous recombination
    • pmid: 18333884
    • A. R. Poteete, Involvement of DNA replication in phage lambda Red-mediated homologous recombination. Mol. Microbiol. 68, 66-74 (2008). doi: 10.1111/j1365-2958.2008.06133.x; pmid: 18333884
    • (2008) Mol. Microbiol , vol.68 , pp. 66-74
    • Poteete, A.R.1
  • 29
    • 84879236720 scopus 로고    scopus 로고
    • Involvement of Escherichia coli DNA replication proteins in phage Lambda Red-mediated homologous recombination
    • pmid: 23840702
    • A. R. Poteete, Involvement of Escherichia coli DNA replication proteins in phage Lambda Red-mediated homologous recombination. PLOS ONE 8, e67440 (2013). doi: 10.1371/ journal.pone.0067440; pmid: 23840702
    • (2013) PLOS ONE , vol.8 , pp. e67440
    • Poteete, A.R.1
  • 30
    • 33846083163 scopus 로고    scopus 로고
    • RecA-independent recombination is efficient but limited by exonucleases
    • pmid: 17182742
    • B. E. Dutra, V. A. Sutera Jr., S. T. Lovett, RecA-independent recombination is efficient but limited by exonucleases. Proc. Natl. Acad. Sci. U.S.A. 104, 216-221 (2007). doi: 10.1073/ pnas.0608293104; pmid: 17182742
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 216-221
    • Dutra, B.E.1    Sutera, V.A.2    Lovett, S.T.3
  • 31
    • 17844374314 scopus 로고    scopus 로고
    • A synthetic multicellular system for programmed pattern formation
    • pmid: 15858574
    • S. Basu, Y. Gerchman, C. H. Collins, F. H. Arnold, R. Weiss, A synthetic multicellular system for programmed pattern formation. Nature 434, 1130-1134 (2005). doi: 10.1038/ nature03461; pmid: 15858574
    • (2005) Nature , vol.434 , pp. 1130-1134
    • Basu, S.1    Gerchman, Y.2    Collins, C.H.3    Arnold, F.H.4    Weiss, R.5
  • 33
    • 84878381909 scopus 로고    scopus 로고
    • Synthetic analog computation in living cells
    • pmid: 23676681
    • R. Daniel, J. R. Rubens, R. Sarpeshkar, T. K. Lu, Synthetic analog computation in living cells. Nature 497, 619-623 (2013). doi: 10.1038/nature12148; pmid: 23676681
    • (2013) Nature , vol.497 , pp. 619-623
    • Daniel, R.1    Rubens, J.R.2    Sarpeshkar, R.3    Lu, T.K.4
  • 34
    • 84897954571 scopus 로고    scopus 로고
    • Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals
    • pmid: 24608181
    • E. J. Olson, L. A. Hartsough, B. P. Landry, R. Shroff, J. J. Tabor, Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals. Nat. Methods 11, 449-455 (2014). doi: 10.1038/nmeth 2884; pmid: 24608181
    • (2014) Nat. Methods , vol.11 , pp. 449-455
    • Olson, E.J.1    Hartsough, L.A.2    Landry, B.P.3    Shroff, R.4    Tabor, J.J.5
  • 35
    • 84866010111 scopus 로고    scopus 로고
    • Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases
    • pmid: 22957093
    • J. A. Mosberg, C. J. Gregg, M. J. Lajoie, H. H. Wang, G. M. Church, Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases. PLOS ONE 7, e44638 (2012). doi: 10.1371/journal. pone.0044638; pmid: 22957093
    • (2012) PLOS ONE , vol.7 , pp. e44638
    • Mosberg, J.A.1    Gregg, C.J.2    Lajoie, M.J.3    Wang, H.H.4    Church, G.M.5
  • 36
    • 0026721914 scopus 로고
    • In vivo production of a stable single-stranded cDNA in Saccharomyces cerevisiae by means of a bacterial retron
    • pmid: 1378616
    • S. Miyata, A. Ohshima, S. Inouye, M. Inouye, In vivo production of a stable single-stranded cDNA in Saccharomyces cerevisiae by means of a bacterial retron. Proc. Natl. Acad. Sci. U.S.A. 89, 5735-5739 (1992). doi: 10.1073/pnas.89.13.5735; pmid: 1378616
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 5735-5739
    • Miyata, S.1    Ohshima, A.2    Inouye, S.3    Inouye, M.4
  • 37
    • 0028017538 scopus 로고
    • Production of single-stranded DNA in mammalian cells by means of a bacterial retron
    • pmid: 7507924
    • O. Mirochnitchenko, S. Inouye, M. Inouye, Production of single-stranded DNA in mammalian cells by means of a bacterial retron. J. Biol. Chem. 269, 2380-2383 (1994).pmid: 7507924
    • (1994) J. Biol. Chem. , vol.269 , pp. 2380-2383
    • Mirochnitchenko, O.1    Inouye, S.2    Inouye, M.3
  • 38
    • 0035794245 scopus 로고    scopus 로고
    • An error-prone T7 RNA polymerase mutant generated by directed evolution
    • pmid: 11828447
    • S. Brakmann, S. Grzeszik, An error-prone T7 RNA polymerase mutant generated by directed evolution. ChemBioChem 2, 212-219 (2001). doi: 10.1002/1439-7633(20010302)2:3<212:: AID-CBIC212>3.0.CO;2-R; pmid: 11828447
    • (2001) ChemBioChem , vol.2 , pp. 212-219
    • Brakmann, S.1    Grzeszik, S.2
  • 39
    • 0024273119 scopus 로고
    • The accuracy of reverse transcriptase from HIV-1
    • pmid: 2460925
    • J. D. Roberts, K. Bebenek, T. A. Kunkel, The accuracy of reverse transcriptase from HIV-1. Science 242, 1171-1173 (1988). doi: 10.1126/science.2460925; pmid: 2460925
    • (1988) Science , vol.242 , pp. 1171-1173
    • Roberts, J.D.1    Bebenek, K.2    Kunkel, T.A.3
  • 40
    • 0027215750 scopus 로고
    • Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots
    • pmid: 7683675
    • K. Bebenek, J. Abbotts, S. H. Wilson, T. A. Kunkel, Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots. J. Biol. Chem. 268, 10324-10334 (1993).pmid: 7683675
    • (1993) J. Biol. Chem. , vol.268 , pp. 10324-10334
    • Bebenek, K.1    Abbotts, J.2    Wilson, S.H.3    Kunkel, T.A.4
  • 41
    • 79955534060 scopus 로고    scopus 로고
    • A system for the continuous directed evolution of biomolecules
    • pmid: 21478873
    • K. M. Esvelt, J. C. Carlson, D. R. Liu, A system for the continuous directed evolution of biomolecules. Nature 472, 499-503 (2011). doi: 10.1038/nature09929; pmid: 21478873
    • (2011) Nature , vol.472 , pp. 499-503
    • Esvelt, K.M.1    Carlson, J.C.2    Liu, D.R.3
  • 42
    • 84901249356 scopus 로고    scopus 로고
    • Universal computing by DNA origami robots in a living animal
    • pmid: 24705510
    • Y. Amir et al., Universal computing by DNA origami robots in a living animal. Nat. Nanotechnol. 9, 353-357 (2014). doi: 10.1038/nnano.2014.58; pmid: 24705510
    • (2014) Nat. Nanotechnol. , vol.9 , pp. 353-357
    • Amir, Y.1
  • 43
    • 79960650829 scopus 로고    scopus 로고
    • Neural network computation with DNA strand displacement cascades
    • pmid: 21776082
    • L. Qian, E. Winfree, J. Bruck, Neural network computation with DNA strand displacement cascades. Nature 475, 368-372 (2011). doi: 10.1038/nature10262; pmid: 21776082
    • (2011) Nature , vol.475 , pp. 368-372
    • Qian, L.1    Winfree, E.2    Bruck, J.3
  • 44
    • 33845411737 scopus 로고    scopus 로고
    • Enzyme-free nucleic acid logic circuits
    • pmid: 17158324
    • G. Seelig, D. Soloveichik, D. Y. Zhang, E. Winfree, Enzyme-free nucleic acid logic circuits. Science 314, 1585-1588 (2006). doi: 10.1126/science.1.132493; pmid: 17158324
    • (2006) Science , vol.314 , pp. 1585-1588
    • Seelig, G.1    Soloveichik, D.2    Zhang, D.Y.3    Winfree, E.4
  • 45
    • 33645028600 scopus 로고    scopus 로고
    • Folding DNA to create nanoscale shapes and patterns
    • pmid: 16541064
    • P. W. Rothemund, Folding DNA to create nanoscale shapes and patterns. Nature 440, 297-302 (2006). doi: 10.1038/ nature04586; pmid: 16541064
    • (2006) Nature , vol.440 , pp. 297-302
    • Rothemund, P.W.1
  • 46
    • 66249137759 scopus 로고    scopus 로고
    • Self-assembly of DNA into nanoscale three-dimensional shapes
    • pmid: 19458720
    • S. M. Douglas et al., Self-assembly of DNA into nanoscale three-dimensional shapes. Nature 459, 414-418 (2009). doi: 10.1038/nature08016; pmid: 19458720
    • (2009) Nature , vol.459 , pp. 414-418
    • Douglas, S.M.1
  • 47
    • 84857335824 scopus 로고    scopus 로고
    • A logic-gated nanorobot for targeted transport of molecular payloads
    • pmid: 22344439
    • S. M. Douglas, I. Bachelet, G. M. Church, A logic-gated nanorobot for targeted transport of molecular payloads. Science 335, 831-834 (2012). doi: 10.1126/science.1214081; pmid: 22344439
    • (2012) Science , vol.335 , pp. 831-834
    • Douglas, S.M.1    Bachelet, I.2    Church, G.M.3
  • 49
    • 84876377597 scopus 로고    scopus 로고
    • A new structural framework for integrating replication protein A into DNA processing machinery
    • pmid: 23303776
    • C. A. Brosey et al., A new structural framework for integrating replication protein A into DNA processing machinery. Nucleic Acids Res. 41, 2313-2327 (2013). doi: 10.1093/nar/gks1332; pmid: 23303776
    • (2013) Nucleic Acids Res. , vol.41 , pp. 2313-2327
    • Brosey, C.A.1
  • 50
    • 84899696363 scopus 로고    scopus 로고
    • Large-scale de novo DNA synthesis: Technologies and applications
    • pmid: 24781323
    • S. Kosuri, G. M. Church, Large-scale de novo DNA synthesis: Technologies and applications. Nat. Methods 11, 499-507 (2014). doi: 10.103S/nmeth.2918; pmid: 24781323
    • (2014) Nat. Methods , vol.11 , pp. 499-507
    • Kosuri, S.1    Church, G.M.2
  • 51
    • 84862520770 scopus 로고    scopus 로고
    • Fiji: An open-source platform for biological-image analysis
    • pmid: 22743772
    • J. Schindelin et al., Fiji: An open-source platform for biological-image analysis. Nat. Methods 9, 676-682 (2012). doi: 10.1038/ nrneth.201.9; pmid: 22743772
    • (2012) Nat. Methods , vol.9 , pp. 676-682
    • Schindelin, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.