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Volumn 340, Issue 6132, 2013, Pages 599-603

Amplifying genetic logic gates

Author keywords

[No Author keywords available]

Indexed keywords

DNA; RNA POLYMERASE;

EID: 84877607428     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1232758     Document Type: Article
Times cited : (389)

References (29)
  • 13
    • 84877607891 scopus 로고    scopus 로고
    • note
    • For example, converting a NOR gate repressed by transcription factors to an OR gate activated by transcription factors requires changing how proteins interact with RNA polymerase (from competitive binding and occlusion to recruitment and initiation) and simultaneous reworking of the basal activity for core promoter elements (from a constitutively active promoter that can be repressed to a weak promoter that does not spontaneously initiate transcription yet that transcription factors activate).
  • 14
    • 84877619275 scopus 로고    scopus 로고
    • Common signal carriers
    • OpenWetWare and Nature Publishing Group New York, chap. 3; available online at
    • C. Wadey, I. Deese, D. Endy, "Common signal carriers," in Adventures in Synthetic Biology (OpenWetWare and Nature Publishing Group New York, 2005), chap. 3; available online at http://hdl.handle.net/1721.1/46337.
    • (2005) Adventures in Synthetic Biology
    • Wadey, C.1    Deese, I.2    Endy, D.3
  • 16
  • 19
    • 84877598740 scopus 로고    scopus 로고
    • note
    • With transistor-based logic, gates use a base, emitter, and collector architecture that classically only allows for control of electrical current at one point on a wire by a single signal. Transcriptor-based logic allows RNA polymerase flow at a single point on DNA to be controlled, in theory, by as many independent recombinases as needed.
  • 23
    • 2142803437 scopus 로고    scopus 로고
    • Materials and methods are available as supplementary materials on
    • Materials and methods are available as supplementary materials on Science Online.
    • Science Online
  • 29
    • 84922756426 scopus 로고    scopus 로고
    • https://biobricks.org/bpa/


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.