Clarifying the roles of homeostasis and allostasis in physiological regulation

Psychological Review

Volumn 121, Issue 2, 2014, Pages 225-247

  Ramsay, Douglas S ^a   Woods, Stephen C ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

Addiction; Obesity; Opioid induced hyperalgesia; Sign reversal; Thermoregulation

Indexed keywords

ADAPTATION; ALLOSTASIS; CHEMICALLY INDUCED; FEEDBACK SYSTEM; HOMEOSTASIS; HUMAN; HYPERALGESIA; OBESITY; OPIATE ADDICTION; PATHOPHYSIOLOGY; PHYSIOLOGY; THERMOREGULATION;

ADAPTATION, PHYSIOLOGICAL; ALLOSTASIS; BODY TEMPERATURE REGULATION; FEEDBACK, PHYSIOLOGICAL; HOMEOSTASIS; HUMANS; HYPERALGESIA; OBESITY; OPIOID-RELATED DISORDERS;

EID: 84910066564     PISSN: 0033295X     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0035942     Document Type: Article

References (169)

1. Ahmed, S. H., & Koob, G. F. (2005). Transition to drug addiction: A negative reinforcement model based on an allostatic decrease in reward function. Psychopharmacology, 180, 473-490. doi:10.1007/s00213- 005-2180-z.
2. Angst, M. S., & Clark, J. D. (2006). Opioid-induced hyperalgesia: A qualitative systematic review. Anesthesiology, 104, 570 -587. doi: 10.1097/00000542-200603000-00025.
3. Baker, T. B., Piper, M. E., McCarthy, D. E., Majeskie, M. R., & Fiore, M. C. (2004). Addiction motivation reformulated: An affective processing model of negative reinforcement. Psychological Review, 111, 33-51. doi:10.1037/0033-295X.111.1.33.
4. Bauman, D. E. (2000). Regulation of nutrient partitioning during lactationHomeostasis and homeorhesis revisited. In P. Cronjé & E. A. Boomker (Eds.), Ruminant physiology: Digestion, metabolism, growth, and reproduction (pp. 311-328). doi:10.1079/9780851994635.0311.
5. Bauman, D. E., & Currie, W. B. (1980). Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis. Journal of Dairy Science, 63, 1514-1529. doi: 10.3168/jds.S0022-0302(80)83111-0.
6. Bernard, C. (1973). Lessons on the phenomena of life common to animals and vegetables: Second lecture, the three forms of life. In L. L. Langley (Ed.), Homeostasis: Origins of the concept (pp. 129-151). Stroudsberg, PA: Dowden, Hutchinson & Ross. (Original work published 1870).
7. Bernstein, I. L. (2003). Interaction between natural motivational systems and those which respond to drugs of abuse. Appetite, 41, 333-334. doi:10.1016/j.appet.2003.06.001.
8. Berntson, G. G., & Cacioppo, J. T. (2000). From homeostasis to allodynamic regulation. In J. T. Cacioppo, L. G. Tassinary, & G. G. Berntson (Eds.), Handbook of psychophysiology (2nd ed., pp. 459-481). Cambridge, England: Cambridge University Press.
9. Berntson, G. G., & Cacioppo, J. T. (2007). Integrative physiology: Homeostasis, allostasis, and the orchestration of systemic physiology. In J. T. Cacioppo, L. G. Tassinary & G. G. Berntson (Eds.), Handbook of psychophysiology (3rd ed., pp. 433- 452). doi:10.1017/ CBO9780511546396.019.
10. Berridge, K. C. (2004). Motivation concepts in behavioral neuroscience. Physiology & Behavior, 81, 179-209. doi:10.1016/j.physbeh.2004.02 .004.
11. Berthoud, H. R., Bereiter, D. A., Trimble, E. R., Siegel, E. G., & Jeanrenaud, B. (1981). Cephalic phase, reflex insulin secretion neuroanatomical and physiological characterization. Diabetologia, 20, 393-401. doi: 10.1007/BF00254508.
12. Bligh, J. (1972). Neuronal models of mammalian temperature regulation. In J. Bligh & R. E. Moore (Eds.), Essays on temperature regulation (pp. 105-120). Amsterdam, the Netherlands: North-Holland.
13. Bligh, J. (1998). Mammalian homeothermy: An integrative thesis. Journal of Thermal Biology, 23, 143-258. doi:10.1016/S0306-4565(98)00014-X.
14. Bligh, J. (2006). A theoretical consideration of the means whereby the mammalian core temperature is defended at a null zone. Journal of Applied Physiology, 100, 1332-1337. doi:10.1152/japplphysiol.01068 .2005.
15. Booth, D. A. (2008). Physiological regulation through learnt control of appetites by contingencies among signals from external and internal environments. Appetite, 51, 433-441. doi:10.1016/j.appet.2008.06.008.
16. Boulant, J. A. (1981). Hypothalamic mechanisms in thermoregulation. Federation Proceedings, 40, 2843-2850.
17. Boulant, J. A. (2000). Role of the preoptic-anterior hypothalamus in thermoregulation and fever. Clinical Infectious Diseases, 31(Suppl. 5), S157-S161. doi:10.1086/317521.
18. Boulant, J. A. (2006). Neuronal basis of Hammel's model for set-point thermoregulation. Journal of Applied Physiology, 100, 1347-1354. doi: 10.1152/japplphysiol.01064.2005.
19. Boulos, Z., & Rosenwasser, A. M. (2004). A chronobiological perspective on allostasis and its application to shift work. In J. Schulkin (Ed.), Allostasis, homeostasis and the costs of physiological adaptation (pp. 228-301). New York, NY: Cambridge University Press.
20. Brobeck, J. R. (1965). Exchange, control, and regulation. In W. S. Yamamoto & J. R. Brobeck (Eds.), Physiological controls and regulations (pp. 1-14). Philadelphia, PA: Saunders.
21. Bruins Slot, L. A., & Colpaert, F. C. (1999). Experimental realization of a signal transduction algorithm. Journal of Theoretical Biology, 200, 39-48. doi:10.1006/jtbi.1999.0973.
22. Bruins Slot, L. A., Koek, W., Tarayre, J. P., & Colpaert, F. C. (2003). Tolerance and inverse tolerance to the hyperalgesic and analgesic actions, respectively, of the novel analgesic, F 13640. European Journal of Pharmacology, 466, 271-279. doi:10.1016/S0014-2999(03)01566-8.
23. Bruins Slot, L. A., Pauwels, P. J., & Colpaert, F. C. (2002). Sign-reversal during persistent activation in μ-opioid signal transduction. Journal of Theoretical Biology, 215, 169-182. doi:10.1006/jtbi.2001.2509.
24. Cabanac, M. (2006). Adjustable set point: To honor Harold T. Hammel. Journal of Applied Physiology, 100, 1338 -1346. doi:10.1152/ japplphysiol.01021.2005.
25. Campfield, L. A., & Smith, F. J. (2003). Blood glucose dynamics and control of meal initiation: A pattern detection and recognition theory. Physiological Reviews, 83, 25-58. doi:10.1152/physrev.00019.2002.
26. Cannon, W. B. (1929). Organization for physiological homeostasis. Physiological Reviews, 9, 399-431.
27. Cannon, W. B. (1932). The wisdom of the body. New York, NY: Norton.
28. Cannon, W. B. (1965). The way of an investigator: A scientist's experiences in medical research. New York, NY: Hafner. (Original work published 1945).
29. Carlisle, H. J., & Ingram, D. L. (1973). The effects of heating and cooling the spinal cord and hypothalamus on thermoregulatory behaviour in the pig. Journal of Physiology, 231, 353-364.
30. Carpenter, R. H. (2004). Homeostasis: A plea for a unified approach. Advances in Physiology Education, 28, 180-187. doi:10.1152/advan .00012.2004.
31. Célèrier, E., Laulin, J. P., Corcuff, J. B., Le Moal, M., & Simonnet, G. (2001). Progressive enhancement of delayed hyperalgesia induced by repeated heroin administration: A sensitization process. Journal of Neuroscience, 21, 4074-4080.
32. Chilliard, Y. (1986). Revue bibliographique: Variations quantitatives et métabolisme des lipides dans les tissus adipeux et le foie au cours du cycle gestation-lactation. 1re partie: chez la ratte [Bibliographic review: Quantitative variations and metabolism of lipids in adipose tissue and the liver during the gestation-lactation cycle: 1. In the rat]. Reproduction Nutrition Development, 26, 1057-1103. doi:10.1051/rnd:19860702.
33. Chilliard, Y., Ferlay, A., Faulconnier, Y., Bonnet, M., Rouel, J., & Bocquier, F. (2000). Adipose tissue metabolism and its role in adaptations to undernutrition in ruminants. Proceedings of the Nutrition Society, 59, 127-134. doi:10.1017/S002966510000015X.
34. Chu, L. F., Angst, M. S., & Clark, D. (2008). Opioid-induced hyperalgesia in humans: Molecular mechanisms and clinical considerations. Clinical Journal of Pain, 24, 479-496. doi:10.1097/AJP.0b013e31816b2f43.
35. Collier, G. H. (1986). The dialogue between the house economist and the resident physiologist. Nutrition & Behavior, 3, 9-26.
36. Collier, G. H., Johnson, D. F., Hill, W. L., & Kaufman, L. W. (1986). The economics of the law of effect. Journal of the Experimental Analysis of Behavior, 46, 113-136. doi:10.1901/jeab.1986.46-113.
37. Collier, G., Johnson, D. F., & Mitchell, C. (1999). The relation between meal size and the time between meals: Effects of cage complexity and food cost. Physiology & Behavior, 67, 339-346. doi:10.1016/S0031- 9384(99)00086-4.
38. Colpaert, F. C. (1996). System theory of pain and of opiate analgesia: No tolerance to opiates. Pharmacological Reviews, 48, 355-402.
39. Colpaert, F. C., Deseure, K., Stinus, L., & Adriaensen, H. (2006). Highefficacy 5-hydroxytryptamine 1A receptor activation counteracts opioid hyperallodynia and affective conditioning. Journal of Pharmacology and Experimental Therapeutics, 316, 892-899. doi:10.1124/jpet.105 .095109.
40. Colpaert, F. C., & Fregnac, Y. (2001). Paradoxical signal transduction in neurobiological systems. Molecular Neurobiology, 24, 145-168. doi: 10.1385/MN:24:1-3:145.
41. Colpaert, F. C., Wu, W. P., Hao, J. X., Royer, I., Sautel, F., Wiesenfeld- Hallin, Z., & Xu, X. J. (2004). High-efficacy 5-HT1A receptor activation causes a curative-like action on allodynia in rats with spinal cord injury. European Journal of Pharmacology, 497, 29-33. doi:10.1016/j.ejphar .2004.06.026.
42. Commission for Thermal Physiology of the International Union of Physiological Sciences. (2001). Glossary of terms for thermal physiology (3rd ed.). Japanese Journal of Physiology, 51, 245-280.
43. Compton, M. A. (1994). Cold-pressor pain tolerance in opiate and cocaine abusers: Correlates of drug type and use status. Journal of Pain and Symptom Management, 9, 462- 473. doi:10.1016/0885- 3924(94)90203-8.
44. Compton, P., Canamar, C. P., Hillhouse, M., & Ling, W. (2012). Hyperalgesia in heroin dependent patients and the effects of opioid substitution therapy. Journal of Pain, 13, 401-409. doi:10.1016/j.jpain.2012.01.001.
45. Compton, P., Charuvastra, V. C., & Ling, W. (2001). Pain intolerance in opioid-maintained former opiate addicts: Effect of long-acting maintenance agent. Drug and Alcohol Dependence, 63, 139-146. doi:10.1016/ S0376-8716(00)00200-3.
46. Csete, M. E., & Doyle, J. C. (2002, March 1). Reverse engineering of biological complexity. Science, 295, 1664-1669. doi:10.1126/science .1069981.
47. Day, T. A. (2005). Defining stress as a prelude to mapping its neurocircuitry: No help from allostasis. Progress in Neuropsychopharmacology & Biological Psychiatry, 29, 1195-1200. doi:10.1016/j.pnpbp.2005.08 .005.
48. Domjan, M. (2005). Pavlovian conditioning: A functional perspective. Annual Review of Psychology, 56, 179-206. doi:10.1146/annurev.psych .55.090902.141409.
49. Drazen, D. L., Vahl, T. P., D'Alessio, D. A., Seeley, R. J., & Woods, S. C. (2006). Effects of a fixed meal pattern on ghrelin secretion: Evidence for a learned response independent of nutrient status. Endocrinology, 147, 23-30. doi:10.1210/en.2005-0973.
50. Dworkin, B. R. (1993). Learning and physiological regulation. Chicago, IL: University of Chicago Press.
51. Dworkin, B. R. (2007). Interoception. In J. T. Cacioppo, L. G. Tassinary, & G. G. Berntson (Eds.), Handbook of psychophysiology (3rd ed., pp. 482-506). doi:10.1017/CBO9780511546396.021.
52. Edwards, S., & Koob, G. F. (2010). Neurobiology of dysregulated motivational systems in drug addiction. Future Neurology, 5, 393-410. doi:10.2217/fnl.10.14.
53. Edwards, S., Vendruscolo, L. F., Schlosburg, J. E., Misra, K. K., Wee, S., Park, P. E.,. Koob, G. F. (2012). Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: Alleviation by CRF1 receptor antagonism. Neuropharmacology, 62, 1142- 1151. doi:10.1016/j.neuropharm.2011.11.006.
54. Ganzel, B. L., Morris, P. A., & Wethington, E. (2010). Allostasis and the human brain: Integrating models of stress from the social and life sciences. Psychological Review, 117, 134-174. doi:10.1037/a0017773.
55. Goldstein, D. S. (2004). Merging of the homeostat theory with the concept of allostatic load. In J. Schulkin (Ed.), Allostasis, homeostasis and the costs of physiological adaptation (pp. 99-112). New York, NY: Cambridge University Press.
56. Goldstein, D. S. (2008). Computer models of stress, allostasis, and acute and chronic diseases. Stress, Neurotransmitters, and Hormones: Neuroendocrine and Genetic Mechanisms, 1148, 223-231. doi:10.1196/ Annals.1410.061.
57. Goldstein, D. S. (2012). Stress, allostatic load, catecholamines, and other neurotransmitters in neurodegenerative diseases. Cellular and Molecular Neurobiology, 32, 661-666. doi:10.1007/s10571-011-9780-4.
58. Goldstein, D. S. (2013). Differential responses of components of the autonomic nervous system. In R. M. Buijs & D. F. Swaab (Vol. Eds.), Handbook of clinical neurology: Vol. 117. Autonomic nervous system (pp. 13-22). doi:10.1016/B978-0-444-53491-0.00002-X.
59. Goldstein, D. S., & Kopin, I. J. (2007). Evolution of concepts of stress. Stress, 10, 109-120. doi:10.1080/10253890701288935.
60. Gordon, C. J. (1983). A review of terms for regulated vs. forced, neurochemical-induced changes in body temperature. Life Sciences, 32, 1285-1295. doi:10.1016/0024-3205(83)90802-0.
61. Gordon, C. J. (2001). The therapeutic potential of regulated hypothermia. Emergency Medicine Journal, 18, 81-89. doi:10.1136/emj.18.2.81.
62. Gordon, C. J. (2005). Temperature and toxicology: An integrative, comparative, and environmental approach. doi:10.1201/9781420037906.
63. Gordon, C. J. (2009). Autonomic nervous system: Central thermoregulatory control. In L. R. Squire (Ed.), Encyclopedia of neuroscience (Vol. 1, pp. 891-898). doi:10.1016/B978-008045046-9.00650-1.
64. Gordon, C. J., Rowsey, P. J., & Yang, Y.-L. (2002). Effect of repeated nicotine exposure on core temperature and motor activity in male and female rats. Journal of Thermal Biology, 27, 485-492. doi:10.1016/ S0306-4565(02)00021-9.
65. Gourley, S. L., Swanson, A. M., & Koleske, A. J. (2013). Corticosteroidinduced neural remodeling predicts behavioral vulnerability and resilience. Journal of Neuroscience, 33, 3107-3112. doi:10.1523/ JNEUROSCI.2138-12.2013.
66. Guyton, A. C. (1982). Human physiology and mechanisms of disease (3rd ed.). Philadelphia, PA: Saunders.
67. Hammel, H. T. (1965). Neurons and temperature regulation. In W. S. Yamamoto & J. R. Brobeck (Eds.), Physiological controls and regulations (pp. 71-97). Philadelphia, PA: Saunders.
68. Hammel, H. T. (1970). Concept of the adjustable set temperature. In J. D. Hardy, A. P. Gagge, & J. A. J. Stolwijk (Eds.), Physiological and behavioral temperature regulation (pp. 676-683). Springfield, IL: Charles C Thomas.
69. Hammel, H. T. (1988). Anesthetics and body-temperature regulation. Anesthesiology, 68, 833-835. doi:10.1097/00000542-198806000-00001.
70. Hammel, H. T. (1989). Homeostasis: Embracing negative feedback enhanced and sustained by positive feedback. In C. V. Paganelli & L. E. Farhi (Eds.), Physiological function in special environments (pp. 191- 202). doi:10.1007/978-1-4612-3556-9_15.
71. Hammel, H. T. (1990). Negative plus positive feedback. In J. Bligh & K. Voigt (Eds.), Thermoreception and temperature regulation (pp. 174- 182). doi:10.1007/978-3-642-75076-2_17.
72. Hammel, H. T., Jackson, D. C., Stolwijk, J. A., Hardy, J. D., & Strømme, S. B. (1963). Temperature regulation by hypothalamic proportional control with an adjustable set point. Journal of Applied Physiology, 18, 1146-1154.
73. Hammel, H. T., & Simon, E. (1994). Salt gland excretion enhanced during cross circulation of blood between two Pekin ducks: Evidence for positive feedback. In K. Pleschka & R. d. Gerstberger (Eds.), Integrative and cellular aspects of autonomic functions: Temperature and osmoregulation- Proceedings of the International Symposium on Integrative and Cellular Aspects of Autonomic Functions held in Bad Nauheim (Germany) on 29-30 July 1993 (pp. 497-508). Montrouge, France: J. Libbey Eurotext.
74. Hardy, J. D. (1965). The "set-point" concept in physiological temperature regulation. In W. S. Yamamoto & J. R. Brobeck (Eds.), Physiological controls and regulations (pp. 98-116). Philadelphia, PA: Saunders.
75. Herman, J. P. (2013). Neural control of chronic stress adaptation. Frontiers in Behavioral Neuroscience, 7, Article 61. doi:10.3389/fnbeh.2013 .00061.
76. Jacob, F. (1977, June 10). Evolution and tinkering. Science, 196, 1161- 1166. doi:10.1126/science.860134.
77. Johansen, K. (1961). Temperature regulation in the nine-banded armadillo (Dasypus novemcinctus mexicanus). Physiological Zoölogy, 34, 126- 144.
78. Kaiyala, K. J., Chan, B., & Ramsay, D. S. (2012). Robust thermoregulatory overcompensation, rather than tolerance, develops with serial administrations of 70% nitrous oxide to rats. Journal of Thermal Biology, 37, 30-40. doi:10.1016/j.jtherbio.2011.10.004.
79. Kaiyala, K. J., & Ramsay, D. S. (2005). Assessment of heat production, heat loss, and core temperature during nitrous oxide exposure: A new paradigm for studying drug effects and opponent responses. AmericanJournal of Physiology: Regulatory, Integrative and Comparative Physiology, 288, R692-R701. doi:10.1152/ajpregu.00412.2004.
80. Kanosue, K., Crawshaw, L. I., Nagashima, K., & Yoda, T. (2010). Concepts to utilize in describing thermoregulation and neurophysiological evidence for how the system works. European Journal of Applied Physiology, 109, 5-11. doi:10.1007/s00421-009-1256-6.
81. Karatsoreos, I. N., & McEwen, B. S. (2011). Psychobiological allostasis: Resistance, resilience and vulnerability. Trends in Cognitive Sciences, 15, 576-584. doi:10.1016/j.tics.2011.10.005.
82. Katz, L. M., Frank, J. E., McGwin, G., Jr., Finch, A., & Gordon, C. J. (2012). Induction of a prolonged hypothermic state by drug-induced reduction in the thermoregulatory set-point. Therapeutic Hypothermia and Temperature Management, 2, 61-66. doi:10.1089/ther.2012.0011.
83. Kennedy, G. C. (1950). The hypothalamic control of food intake in rats. Proceedings of the Royal Society B: Biological Sciences, 137, 535-549. doi:10.1098/rspb.1950.0065.
84. Kitano, H., Oda, K., Kimura, T., Matsuoka, Y., Csete, M., Doyle, J., & Muramatsu, M. (2004). Metabolic syndrome and robustness tradeoffs. Diabetes, 53(Suppl. 3), S6-S15. doi:10.2337/diabetes.53.suppl_3.S6.
85. Kobayashi, S., Okazawa, M., Hori, A., Matsumura, K., & Hosokawa, H. (2006). Paradigm shift in sensory system: Animals do not have sensors. Journal of Thermal Biology, 31, 19-23. doi:10.1016/j.jtherbio.2005.11 .011.
86. Koob, G. F. (2004). Allostatic view of motivation: Implications for psychopathology. In R. A. Bevins & M. T. Bardo (Eds.), Nebraska Symposium on Motivation: Vol. 50. Motivational factors in the etiology of drug abuse (pp. 1-18). Lincoln: University of Nebraska Press.
87. Koob, G. F. (2009). Dynamics of neuronal circuits in addiction: Reward, antireward, and emotional memory. Pharmacopsychiatry, 42(Suppl. 1), S32-S41. doi:10.1055/s-0029-1216356.
88. Koob, G. F. (2010). The role of CRF and CRF-related peptides in the dark side of addiction. Brain Research, 1314, 3-14. doi:10.1016/j.brainres .2009.11.008.
89. Koob, G. F., & Le Moal, M. (1997, October 3). Drug abuse: Hedonic homeostatic dysregulation. Science, 278, 52-58. doi:10.1126/science .278.5335.52.
90. Koob, G. F., & Le Moal, M. (2001). Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology, 24, 97-129. doi: 10.1016/S0893-133X(00)00195-0.
91. Koob, G. F., & Le Moal, M. (2004). Drug addiction and allostasis. In J. Schulkin (Ed.), Allostasis, homeostasis and the costs of physiological adaptation (pp. 150-163). New York, NY: Cambridge University Press.
92. Koob, G. F., & Le Moal, M. (2005). Plasticity of reward neurocircuitry and the "dark side" of drug addiction. Nature Neuroscience, 8, 1442-1444. doi:10.1038/nn1105-1442.
93. Koob, G. F., & Le Moal, M. (2008). Addiction and the brain antireward system. Annual Review of Psychology, 59, 29-53. doi:10.1146/annurev .psych.59.103006.093548.
94. Kuenzel, W. J., Beck, M. M., & Teruyama, R. (1999). Neural sites and pathways regulating food intake in birds: A comparative analysis to mammalian systems. Journal of Experimental Zoology, 283, 348-364. doi:10.1002/(SICI)1097-010X(19990301/01)283:4/5<348::AIDJEZ5>3.0.C O;2-5.
95. Langley, L. L. (1973). Homeostasis: Origins of the concept. Stroudsburg, PA: Dowden.
96. Lê, A. D., Poulos, C. X., & Cappell, H. (1979, November 30). Conditioned tolerance to the hypothermic effect of ethyl-alcohol. Science, 206, 1109-1110. doi:10.1126/science.493999.
97. Lee, M., Silverman, S. M., Hansen, H., Patel, V. B., & Manchikanti, L. (2011). A comprehensive review of opioid-induced hyperalgesia. Pain Physician, 14, 145-161.
98. Le Moal, M. (2007). Historical approach and evolution of the stress concept: A personal account. Psychoneuroendocrinology, 32(Suppl. 1), S3-S9. doi:10.1016/j.psyneuen.2007.03.019.
99. Le Moal, M., & Koob, G. F. (2007). Drug addiction: Pathways to the disease and pathophysiological perspectives. European Neuropsychopharmacology, 17, 377-393. doi:10.1016/j.euroneuro.2006.10.006.
100. López-Barneo, J., Ortega-Sáenz, P., Pardal, R., Pascual, A., & Piruat, J. I. (2008). Carotid body oxygen sensing. European Respiratory Journal, 32, 1386-1398. doi:10.1183/09031936.00056408.
101. Mansfield, J. G., & Cunningham, C. L. (1980). Conditioning and extinction of tolerance to the hypothermic effect of ethanol in rats. Journal of Comparative and Physiological Psychology, 94, 962-969. doi:10.1037/ h0077824.
102. Mao, J. (2002). Opioid-induced abnormal pain sensitivity: Implications in clinical opioid therapy. Pain, 100, 213-217. doi:10.1016/S0304- 3959(02)00422-0.
103. Mayer, J. (1955). Regulation of energy intake and the body weight: The glucostatic theory and the lipostatic hypothesis. Annals of the New York Academy of Sciences, 63, 15- 43. doi:10.1111/j.1749-6632.1955 .tb36543.x.
104. McAllen, R. M., Tanaka, M., Ootsuka, Y., & McKinley, M. J. (2010). Multiple thermoregulatory effectors with independent central controls. European Journal of Applied Physiology, 109, 27-33. doi:10.1007/ s00421-009-1295-z.
105. McEwen, B. S., & Gianaros, P. J. (2010). Central role of the brain in stress and adaptation: Links to socioeconomic status, health, and disease. Annals of the New York Academy of Sciences, 1186, 190-222. doi: 10.1111/j.1749-6632.2009.05331.x.
106. McEwen, B. S., & Stellar, E. (1993). Stress and the individual: Mechanisms leading to disease. Archives of Internal Medicine, 153, 2093- 2101. doi:10.1001/archinte.1993.00410180039004.
107. McEwen, B. S., & Wingfield, J. C. (2010). What is in a name? Integrating homeostasis, allostasis and stress. Hormones and Behavior, 57, 105- 111. doi:10.1016/j.yhbeh.2009.09.011.
108. Mercer, J. B., & Hammel, H. T. (1989). Total calorimetry and temperature regulation in the nine-banded armadillo. Acta Physiologica Scandinavica, 135, 579-589. doi:10.1111/j.1748-1716.1989.tb08620.x.
109. Moore-Ede, M. C. (1986). Physiology of the circadian timing system: Predictive versus reactive homeostasis. American Journal of Physiology, 250, R737-R752.
110. Morris, M. J., Na, E. S., & Johnson, A. K. (2008). Salt craving: The psychobiology of pathogenic sodium intake. Physiology & Behavior, 94, 709-721. doi:10.1016/j.physbeh.2008.04.008.
111. Morrison, S. F., & Nakamura, K. (2011). Central neural pathways for thermoregulation. Frontiers in Bioscience, 16, 74-104. doi:10.2741/ 3677.
112. Mrosovsky, N. (1990). Rheostasis: The physiology of change. New York, NY: Oxford University Press.
113. Na, E. S., Morris, M. J., Johnson, R. F., Beltz, T. G., & Johnson, A. K. (2007). The neural substrates of enhanced salt appetite after repeated sodium depletions. Brain Research, 1171, 104 -110. doi:10.1016/j .brainres.2007.07.033.
114. Nicolaidis, S. (2011). Metabolic and humoral mechanisms of feeding and genesis of the ATP/ADP/AMP concept. Physiology & Behavior, 104, 8-14. doi:10.1016/j.physbeh.2011.04.058.
115. Olausson, P., Kiraly, D. D., Gourley, S. L., & Taylor, J. R. (2013). Persistent effects of prior chronic exposure to corticosterone on rewardrelated learning and motivation in rodents. Psychopharmacology, 225, 569-577. doi:10.1007/s00213-012-2844-4.
116. Ossipov, M. H., Lai, J., King, T., Vanderah, T. W., Malan, T. P., Jr., Hruby, V. J., & Porreca, F. (2004). Antinociceptive and nociceptive actions of opioids. Journal of Neurobiology, 61, 126-148. doi:10.1002/neu.20091.
117. Ossipov, M. H., Lai, J., King, T., Vanderah, T. W., & Porreca, F. (2005). Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure. Biopolymers, 80, 319-324. doi:10.1002/bip.20254.
118. Ossipov, M. H., Lai, J., Vanderah, T. W., & Porreca, F. (2003). Induction of pain facilitation by sustained opioid exposure: Relationship to opioidantinociceptive tolerance. Life Sciences, 73, 783-800. doi:10.1016/ S0024-3205(03)00410-7.
119. Peters, A., & McEwen, B. S. (2012). Introduction for the allostatic load special issue. Physiology & Behavior, 106, 1-4. doi:10.1016/j.physbeh .2011.12.019.
120. Power, M. L. (2004). Viability as opposed to stability: An evolutionary perspective on physiological regulation. In J. Schulkin (Ed.), Allostasis, homeostasis and the costs of physiological adaptation (pp. 343-364). New York, NY: Cambridge University Press.
121. Power, M. L., & Schulkin, J. (2012). Maternal obesity, metabolic disease, and allostatic load. Physiology & Behavior, 106, 22-28. doi:10.1016/j .physbeh.2011.09.011.
122. Ramsay, D. S., Kaiyala, K. J., Leroux, B. G., & Woods, S. C. (2005). Individual differences in initial sensitivity and acute tolerance predict patterns of chronic drug tolerance to nitrous-oxide-induced hypothermia in rats. Psychopharmacology, 181, 48-59. doi:10.1007/s00213-005- 2219-1.
123. Ramsay, D. S., Seeley, R. J., Bolles, R. C., & Woods, S. C. (1996). Ingestive homeostasis: The primacy of learning. In E. D. Capaldi (Ed.), Why we eat what we eat: The psychology of eating (pp. 11-27). doi: 10.1037/10291-001.
124. Ramsay, D. S., & Woods, S. C. (1997). Biological consequences of drug administration: Implications for acute and chronic tolerance. Psychological Review, 104, 170-193. doi:10.1037/0033-295X.104.1.170.
125. Refinetti, R. (2010). The circadian rhythm of body temperature. Frontiers in Bioscience, 15, 564-594. doi:10.2741/3634.
126. Ren, Z. Y., Shi, J., Epstein, D. H., Wang, J., & Lu, L. (2009). Abnormal pain response in pain-sensitive opiate addicts after prolonged abstinence predicts increased drug craving. Psychopharmacology, 204, 423-429. doi:10.1007/s00213-009-1472-0.
127. Romanovsky, A. A. (2007a). Temperature regulation. In O. H. Petersen (Ed.), Lecture notes: Human physiology (5th ed., pp. 603-615). Malden, MA: Blackwell.
128. Romanovsky, A. A. (2007b). Thermoregulation: Some concepts have changed-Functional architecture of the thermoregulatory system. American Journal of Physiology: Regulatory Integrative and Comparative Physiology, 292, R37-R46. doi:10.1152/ajpregu.00668.2006.
129. Satinoff, E. (1978, July 7). Neural organization and evolution of thermal regulation in mammals. Science, 201, 16 -22. doi:10.1126/science .351802.
130. Satinoff, E. (2005). Thermoregulation. In I. Q. Whishaw & B. Kolb (Eds.), The behavior of the laboratory rat: A handbook with tests (pp. 226- 235). Oxford, England: Oxford University Press.
131. Schulkin, J. (2011). Social allostasis: Anticipatory regulation of the internal milieu. Frontiers in Evolutionary Neuroscience, 2, Article 111. doi: 10.3389/fnevo.2010.00111.
132. Seeley, R. J., Ramsay, D. S., & Woods, S. C. (1997). Regulation of food intake: Interactions between learning and physiology. In M. E. Bouton & M. S. Fanselow (Eds.), Learning, motivation, and cognition: The functional behaviorism of Robert C. Bolles (pp. 99-115). doi:10.1037/ 10223-005.
133. Selye, H. (1973). Homeostasis and heterostasis. Perspectives in Biology and Medicine, 16, 441-445. Sherrington, C. S. (1906). The integrative action of the nervous system. New York, NY: Scribner's.
134. Siegel, S. (2001). Pavlovian conditioning and drug overdose: When tolerance fails. Addiction Research & Theory, 9, 503-513. doi:10.3109/ 16066350109141767.
135. Siegel, S. (2008). Learning and the wisdom of the body. Learning & Behavior, 36, 242-252. doi:10.3758/LB.36.3.242.
136. Siegel, S., & Allan, L. G. (1998). Learning and homeostasis: Drug addiction and the McCollough effect. Psychological Bulletin, 124, 230-239. doi:10.1037/0033-2909.124.2.230.
137. Siegel, S., Baptista, M. A., Kim, J. A., McDonald, R. V., & Weise-Kelly, L. (2000). Pavlovian psychopharmacology: The associative basis of tolerance. Experimental and Clinical Psychopharmacology, 8, 276-293. doi:10.1037/1064-1297.8.3.276.
138. Siegel, S., Hinson, R. E., Krank, M. D., & McCully, J. (1982, April 23). Heroin "overdose" death: Contribution of drug-associated environmental cues. Science, 216, 436-437. doi:10.1126/science.7200260.
139. Solomon, R. L. (1980). The opponent-process theory of acquired motivation: The costs of pleasure and the benefits of pain. American Psychologist, 35, 691-712. doi:10.1037/0003-066X.35.8.691.
140. Solomon, R. L., & Corbit, J. D. (1974). An opponent-process theory of motivation: I. Temporal dynamics of affect. Psychological Review, 81, 119-145. doi:10.1037/h0036128.
141. Somjen, G. G. (1992). The missing error signal: Regulation beyond negative feedback. News in Physiological Sciences, 7, 184-185.
142. Soodak, H., & Iberall, A. (1978, August 18). Homeokinetics: A physical science for complex systems. Science, 201, 579-582. doi:10.1126/ science.201.4356.579.
143. Sterling, P. (2004). Principles of allostasis: Optimal design, predictive regulation, pathophysiology, and rational therapeutics. In J. Schulkin (Ed.), Allostasis, homeostasis and the costs of physiological adaptation (pp. 17-64). New York, NY: Cambridge University Press.
144. Sterling, P. (2012). Allostasis: A model of predictive regulation. Physiology & Behavior, 106, 5-15. doi:10.1016/j.physbeh.2011.06.004.
145. Sterling, P., & Eyer, J. (1988). Allostasis: A new paradigm to explain arousal pathology. In S. Fisher & J. T. Reason (Eds.), Handbook of life stress, cognition, and health (pp. 629-649). Chichester, England: Wiley.
146. Strubbe, J. H., & van Dijk, G. (2002). The temporal organization of ingestive behaviour and its interaction with regulation of energy balance. Neuroscience & Biobehavioral Reviews, 26, 485-498. doi:10.1016/ S0149-7634(02)00016-7.
147. Strubbe, J. H., & Woods, S. C. (2004). The timing of meals. Psychological Review, 111, 128-141. doi:10.1037/0033-295X.111.1.128.
148. Székely, M., Szelényi, Z., Pétervári, E., & Balaskó, M. (2001). Thermoregulatory "overshoot" reactions in cold-adapted rats. Journal of Thermal Biology, 26, 491-497. doi:10.1016/S0306-4565(01)00066-3.
149. Tajino, K., Hosokawa, H., Maegawa, S., Matsumura, K., Dhaka, A., & Kobayashi, S. (2011). Cooling-sensitive TRPM8 is thermostat of skin temperature against cooling. PLoS One, 6(3), Article e17504. doi: 10.1371/journal.pone.0017504.
150. Teff, K. L. (2011). How neural mediation of anticipatory and compensatory insulin release helps us tolerate food. Physiology & Behavior, 103, 44-50. doi:10.1016/j.physbeh.2011.01.012.
151. Vahl, T. P., Drazen, D. L., Seeley, R. J., D'Alessio, D. A., & Woods, S. C. (2010). Meal-anticipatory glucagon-like peptide-1 secretion in rats. Endocrinology, 151, 569-575. doi:10.1210/en.2009-1002.
152. Vanderah, T. W., Suenaga, N. M., Ossipov, M. H., Malan, T. P., Jr., Lai, J., & Porreca, F. (2001). Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance. Journal of Neuroscience, 21, 279-286.
153. Waddington, C. H. (1957). The strategy of the genes: A discussion of some aspects of theoretical biology. London, England: Allen & Unwin. Waddington, C. H. (1968). Towards a theoretical biology: An IUBS symposium-Vol. 1. Prolegomena. Edinburgh, Scotland: Edinburgh University Press.
154. Werner, J. (2010). System properties, feedback control and effector coordination of human temperature regulation. European Journal of Applied Physiology, 109, 13-25. doi:10.1007/s00421-009-1216-1.
155. White, J. M. (2004). Pleasure into pain: The consequences of long-term opioid use. Addictive Behaviors, 29, 1311-1324. doi:10.1016/j.addbeh .2004.06.007.
156. Wiener, N. (1948). Cybernetics. New York, NY: Wiley. Wirtshafter, D., & Davis, J. D. (1977). Set points, settling points, and the control of body weight. Physiology & Behavior, 19, 75-78. doi:10.1016/ 0031-9384(77)90162-7.
157. Woods, S. C. (1991). The eating paradox: How we tolerate food. Psychological Review, 98, 488-505. doi:10.1037/0033-295X.98.4.488.
158. Woods, S. C. (2009). The control of food intake: Behavioral versus molecular perspectives. Cell Metabolism, 9, 489-498. doi:10.1016/j .cmet.2009.04.007.
159. Woods, S. C., Decke, E., & Vasselli, J. R. (1974). Metabolic hormones and regulation of body-weight. Psychological Review, 81, 26-43. doi: 10.1037/h0035927.
160. Woods, S. C., & Ramsay, D. S. (2000). Pavlovian influences over food and drug intake. Behavioural Brain Research, 110, 175-182. doi:10.1016/ S0166-4328(99)00194-1.
161. Woods, S. C., & Ramsay, D. S. (2007). Homeostasis: Beyond Curt Richter. Appetite, 49, 388-398. doi:10.1016/j.appet.2006.09.015.
162. Woods, S. C., & Strubbe, J. H. (1994). The psychobiology of meals. Psychonomic Bulletin & Review, 1, 141-155. doi:10.3758/BF03200770.
163. Woods, S. C., Vasselli, J. R., Kaestner, E., Szakmary, G. A., Milburn, P., & Vitiello, M. V. (1977). Conditioned insulin-secretion and meal feeding in rats. Journal of Comparative and Physiological Psychology,
164. Wyndham, C. H., & Atkins, A. R. (1968). A physiological scheme and mathematical model of temperature regulation in man. Pflügers Arch, 303, 14-30. doi:10.1007/BF00586824.
165. Yang, Y., & Gordon, C. J. (1996). Ambient temperature limits and stability of temperature regulation in telemetered male and female rats. Journal of Thermal Biology, 21, 353-363. doi:10.1016/S0306-4565(96)00021-6.
166. Yates, F. E. (1982). The 10th J. A. F. Stevenson Memorial Lecture: Outline of a physical theory of physiological systems. Canadian Journal of Physiology and Pharmacology, 60, 217-248. doi:10.1139/y82-035.
167. Yates, F. E. (1994). Order and complexity in dynamical systems: Homeodynamics as a generalized mechanics for biology. Mathematical and Computer Modelling, 19, 49-74. doi:10.1016/0895-7177(94)90189-9.
168. Yates, F. E. (1996). Homeostasis. In J. E. Birren (Ed.), Encyclopedia of gerontology: Age, aging, and the aged (Vol. 1, pp. 679-686). San Diego, CA: Academic Press.
169. Yates, F. E. (2008). Homeokinetics/homeodynamics: A physical heuristic for life and complexity. Ecological Psychology, 20, 148-179. doi: 10.1080/10407410801977546.