Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance

Journal of Neuroscience

Volumn 21, Issue 1, 2001, Pages 279-286

  Vanderah, T W ^a   Suenaga, N M H ^a   Ossipov, M H ^a   Malan T P , Jr ^a   Lai, J ^a   Porreca, F ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Descending facilitation; Lidocaine; Opioid tolerance; Opioid induced pain; Supraspinal spinal synergy; Tactile allodynia; Thermal hyperalgesia

Indexed keywords

LIDOCAINE; MORPHINE; OPIATE;

ALLODYNIA; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; DOSE RESPONSE; DRUG ACTIVATION; DRUG PELLET; DRUG POTENCY; EFFERENT NERVE; FACILITATION; HYPERALGESIA; MALE; MEDULLA OBLONGATA; MINIPUMP; NONHUMAN; PAIN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SPINAL CORD LESION;

EID: 0035141560     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-01-00279.2001     Document Type: Article

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