메뉴 건너뛰기




Volumn 9, Issue 10, 2014, Pages

Mathematical modeling of Interleukin-35 promoting tumor growth and angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COLONY STIMULATING FACTOR 1; INTERLEUKIN 35; INTERLEUKIN 35 INHIBITOR; OXYGEN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VASCULOTROPIN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-35, MOUSE;

EID: 84910062923     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110126     Document Type: Article
Times cited : (46)

References (92)
  • 1
    • 84874275252 scopus 로고    scopus 로고
    • Tumor-derived il-35 promotes tumor growth by enhancing myeloid cell accumulation and angiogenesis
    • Wang Z, Liu JQ, Liu Z, Shen R, Zhang G, et al. (2013) Tumor-derived il-35 promotes tumor growth by enhancing myeloid cell accumulation and angiogenesis. J Immuno 190:2415-2423.
    • (2013) J Immuno , vol.190 , pp. 2415-2423
    • Wang, Z.1    Liu, J.Q.2    Liu, Z.3    Shen, R.4    Zhang, G.5
  • 2
    • 84885362636 scopus 로고    scopus 로고
    • Assessing the role of il-35 in colorectal cancer progression and prognosis
    • Zeng JC, Zhang Z, Li TY, Liang YF, Wang HM, et al. (2013) Assessing the role of il-35 in colorectal cancer progression and prognosis. Int J Clin Exp Pathol 6:1806-1816.
    • (2013) Int J Clin Exp Pathol , vol.6 , pp. 1806-1816
    • Zeng, J.C.1    Zhang, Z.2    Li, T.Y.3    Liang, Y.F.4    Wang, H.M.5
  • 3
    • 84872407360 scopus 로고    scopus 로고
    • Il-35 over-expression increases apoptosis sensitivity and suppresses cell growth in human cancer cells
    • Long J, Zhang X, Wena M, Kong Q, Lv Z, et al. (2013) Il-35 over-expression increases apoptosis sensitivity and suppresses cell growth in human cancer cells. Biochemical and Biophysical Research Communications 430:364-369.
    • (2013) Biochemical and Biophysical Research Communications , vol.430 , pp. 364-369
    • Long, J.1    Zhang, X.2    Wena, M.3    Kong, Q.4    Lv, Z.5
  • 4
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory t cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage UK, Moore TT, Joo HG, Tanaka Y, Herrmann V, et al. (2002) Prevalence of regulatory t cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol 169:2756-2761.
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.G.3    Tanaka, Y.4    Herrmann, V.5
  • 5
    • 28544433483 scopus 로고    scopus 로고
    • The expression of the regulatory t cell-specific forkhead box transcription factor foxp3 is associated with poor prognosis in ovarian cancer
    • Wolf D, Wolf AM, Rumpold H, Fiegl H, Zeimet AG, et al. (2005) The expression of the regulatory t cell-specific forkhead box transcription factor foxp3 is associated with poor prognosis in ovarian cancer. Clin Cancer Res 11:8326-8331.
    • (2005) Clin Cancer Res , vol.11 , pp. 8326-8331
    • Wolf, D.1    Wolf, A.M.2    Rumpold, H.3    Fiegl, H.4    Zeimet, A.G.5
  • 7
    • 79251586227 scopus 로고    scopus 로고
    • Il-9 production by regulatory t cells recruits mast cells that are essential for regulatory t cellonduced immune suppression
    • Eller K, Wolf D, Huber JM, Metz M, Mayer G, et al. (2011) Il-9 production by regulatory t cells recruits mast cells that are essential for regulatory t cellonduced immune suppression. J Immunology 186:83-91.
    • (2011) J Immunology , vol.186 , pp. 83-91
    • Eller, K.1    Wolf, D.2    Huber, J.M.3    Metz, M.4    Mayer, G.5
  • 8
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine il-35 contributes to regulatory t-cell function
    • Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, et al. (2007) The inhibitory cytokine il-35 contributes to regulatory t-cell function. Nature 450:566-569.
    • (2007) Nature , vol.450 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3    Boyd, K.4    Wang, Y.5
  • 9
    • 55149104594 scopus 로고    scopus 로고
    • Interleukin-35: Odd one out or part of the family?
    • Collison LW, Vignali DAA (2008) Interleukin-35: odd one out or part of the family? Immunol Rev 226:248-262.
    • (2008) Immunol Rev , vol.226 , pp. 248-262
    • Collison, L.W.1    Vignali, D.A.A.2
  • 12
    • 79959572627 scopus 로고    scopus 로고
    • Human regulatory t cells require interleukin-35 to mediate suppression and infectious tolerance
    • Chaturvedi V, Collison LW, Guy CS, Workman CJ, Vignali DAA (2011) Human regulatory t cells require interleukin-35 to mediate suppression and infectious tolerance. J Immunol 186:6661-6666.
    • (2011) J Immunol , vol.186 , pp. 6661-6666
    • Chaturvedi, V.1    Collison, L.W.2    Guy, C.S.3    Workman, C.J.4    Vignali, D.A.A.5
  • 14
    • 84864124859 scopus 로고    scopus 로고
    • Il-12 family cytokines: Immunological playmakers
    • Vignali DAA, Kuchroo VK (2012) Il-12 family cytokines: immunological playmakers. Nature immunology 13:722-728.
    • (2012) Nature Immunology , vol.13 , pp. 722-728
    • Vignali, D.A.A.1    Kuchroo, V.K.2
  • 16
    • 80053474761 scopus 로고    scopus 로고
    • Identification of epstein-barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer
    • Nishino R, Takano A, Oshita H, Ishikawa N, Akiyama H, et al. (2011) Identification of epstein-barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer. Clin Cancer Res 17:6272-6286.
    • (2011) Clin Cancer Res , vol.17 , pp. 6272-6286
    • Nishino, R.1    Takano, A.2    Oshita, H.3    Ishikawa, N.4    Akiyama, H.5
  • 17
    • 20244390313 scopus 로고    scopus 로고
    • Analysis of interleukin-27 (ebi3/p28) expression in epstein-barr virus- and human t-cell leukemia virus type 1-associated lymphomas: Heterogeneous expression of ebi3 subunit by tumoral cells
    • Larousserie F, Bardel E, Pflanz S, Arnulf B, Lome-Maldonado C, et al. (2005) Analysis of interleukin-27 (ebi3/p28) expression in epstein-barr virus- and human t-cell leukemia virus type 1-associated lymphomas: heterogeneous expression of ebi3 subunit by tumoral cells. Am J Pathol 166:1217-1228.
    • (2005) Am J Pathol , vol.166 , pp. 1217-1228
    • Larousserie, F.1    Bardel, E.2    Pflanz, S.3    Arnulf, B.4    Lome-Maldonado, C.5
  • 18
    • 0036839934 scopus 로고    scopus 로고
    • Frequent expression of the epstein-barr virus (ebv)-induced gene, ebi3, an il-12 p40-related cytokine, in hodgkin and reed-sternberg cells
    • Niedobitek G, Päolt D, Teichmann M, Devergne O (2002) Frequent expression of the epstein-barr virus (ebv)-induced gene, ebi3, an il-12 p40-related cytokine, in hodgkin and reed-sternberg cells. J Pathol 198:310-316.
    • (2002) J Pathol , vol.198 , pp. 310-316
    • Niedobitek, G.1    Päolt, D.2    Teichmann, M.3    Devergne, O.4
  • 20
    • 84877990693 scopus 로고    scopus 로고
    • Polarization and reprogramming of myeloid-derived suppressor cells
    • Yang WC, Ma G, Chen SH, Pan PY (2013) Polarization and reprogramming of myeloid-derived suppressor cells. J Mol Cell Biol 5:207-209.
    • (2013) J Mol Cell Biol , vol.5 , pp. 207-209
    • Yang, W.C.1    Ma, G.2    Chen, S.H.3    Pan, P.Y.4
  • 21
    • 84910105408 scopus 로고    scopus 로고
    • Dying to live: How our bodies fight disease
    • Kendall M (1998) Dying to live: How our bodies fight disease. Cambridge University.
    • (1998) Cambridge University
    • Kendall, M.1
  • 24
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, et al. (2004) The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25:677-686.
    • (2004) Trends Immunol , vol.25 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5
  • 25
    • 0842348242 scopus 로고    scopus 로고
    • Mathematical modeling of the use of macrophages as vehicles for drug delivery to hypoxic tumor sites
    • Owen MR, Byrne HM, Lewis CE (2004) Mathematical modeling of the use of macrophages as vehicles for drug delivery to hypoxic tumor sites. J Theore Biol 226:377-391.
    • (2004) J Theore Biol , vol.226 , pp. 377-391
    • Owen, M.R.1    Byrne, H.M.2    Lewis, C.E.3
  • 26
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct m2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • Sica A, Schioppa T, Mantovani A, Allavena P (2006) Tumour-associated macrophages are a distinct m2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy. European J of Cancer 42:717-727.
    • (2006) European J of Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 27
    • 77952525594 scopus 로고    scopus 로고
    • A pivotal role for interleukin-27 in cd8+ t cell functions and generation of cytotoxic t lymphocytes
    • Morishima N, Mizoguchi I, Okumura M, Chiba Y, Xu M, et al. (2010) A pivotal role for interleukin-27 in cd8+ t cell functions and generation of cytotoxic t lymphocytes. J Biomedicine and Biotechnology: doi:10.1155/2010/605483.
    • (2010) J Biomedicine and Biotechnology
    • Morishima, N.1    Mizoguchi, I.2    Okumura, M.3    Chiba, Y.4    Xu, M.5
  • 28
    • 33745639683 scopus 로고    scopus 로고
    • Inactivation of tgf-beta signaling in lung cancer results in increased cdk4 activity that can be rescued by elf
    • Baek HJ, Kim SS, da Silva FM, Volpe EA, Evans S, et al. (2006) Inactivation of tgf-beta signaling in lung cancer results in increased cdk4 activity that can be rescued by elf. Biochem Biophys Res Commun 11:1150-1157.
    • (2006) Biochem Biophys Res Commun , vol.11 , pp. 1150-1157
    • Baek, H.J.1    Kim, S.S.2    Da Silva, F.M.3    Volpe, E.A.4    Evans, S.5
  • 29
    • 35548950221 scopus 로고    scopus 로고
    • Regulatory t-cell inhibition versus depletion: The right choice in cancer immunotherapy
    • Colombo MP, Piconese S (2007) Regulatory t-cell inhibition versus depletion: the right choice in cancer immunotherapy. Nature Reviews Cancer 7:880-887.
    • (2007) Nature Reviews Cancer , vol.7 , pp. 880-887
    • Colombo, M.P.1    Piconese, S.2
  • 30
    • 0029949961 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha enhances secretion of transforming growth factor beta2 in mcf-7 breast cancer cells
    • Danforth DNJ, Sgagias MK (1996) Tumor necrosis factor alpha enhances secretion of transforming growth factor beta2 in mcf-7 breast cancer cells. Clin Cancer Res 2:827-835.
    • (1996) Clin Cancer Res , vol.2 , pp. 827-835
    • Danforth, D.N.J.1    Sgagias, M.K.2
  • 31
    • 0034469045 scopus 로고    scopus 로고
    • Transforming growth factor-beta and brest cancer: Transforming growth factor-beta/smad signaling defects and cancer
    • Kretzschmar M (2000) Transforming growth factor-beta and brest cancer: transforming growth factor-beta/smad signaling defects and cancer. Breast Cancer Res 2:107-115.
    • (2000) Breast Cancer Res , vol.2 , pp. 107-115
    • Kretzschmar, M.1
  • 32
    • 0031685620 scopus 로고    scopus 로고
    • Tgf-beta signal transduction
    • Massagué J (1998) Tgf-beta signal transduction. Annu Rev Biochem 67:753-791.
    • (1998) Annu Rev Biochem , vol.67 , pp. 753-791
    • Massagué, J.1
  • 33
    • 33746475270 scopus 로고    scopus 로고
    • Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
    • Muller AJ, Scherle PA (2006) Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors. Nat Rev Cancer 6:613-625.
    • (2006) Nat Rev Cancer , vol.6 , pp. 613-625
    • Muller, A.J.1    Scherle, P.A.2
  • 35
    • 35348901453 scopus 로고    scopus 로고
    • Basics of tgf-beta and pancreatic cancer
    • Truty MJ, Urrutia R (2007) Basics of tgf-beta and pancreatic cancer. Pancreatology 7:423-435.
    • (2007) Pancreatology , vol.7 , pp. 423-435
    • Truty, M.J.1    Urrutia, R.2
  • 36
    • 84856945806 scopus 로고    scopus 로고
    • + regulatory t cells
    • + regulatory t cells. J Mol Cell Biol 4:29-37.
    • (2012) J Mol Cell Biol , vol.4 , pp. 29-37
    • Tran, D.Q.1
  • 38
    • 84883760514 scopus 로고    scopus 로고
    • Mathematical model of the roles of t cells in inflammatory bowel disease
    • Lo WC, Arsenescu RI, Friedman A (2013) Mathematical model of the roles of t cells in inflammatory bowel disease. Bull Math Biol 75:1417-1433.
    • (2013) Bull Math Biol , vol.75 , pp. 1417-1433
    • Lo, W.C.1    Arsenescu, R.I.2    Friedman, A.3
  • 39
    • 79954471164 scopus 로고    scopus 로고
    • Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of mcp-1
    • Boelte KC, Gordy LE, Joyce S, Thompson MA, Yang L, et al. (2011) Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of mcp-1. PLoS ONE 11:e18534.
    • (2011) PLoS ONE , vol.11 , pp. e18534
    • Boelte, K.C.1    Gordy, L.E.2    Joyce, S.3    Thompson, M.A.4    Yang, L.5
  • 40
    • 34247374339 scopus 로고    scopus 로고
    • Tumorassociated macrophages secrete il-6 and mcp-1 in head and neck squamous cell carcinoma tissue
    • Kross KW, Heimdal JH, Olsnes C, Olofson J, Aarstad HJ (2007) Tumorassociated macrophages secrete il-6 and mcp-1 in head and neck squamous cell carcinoma tissue. Acta Otolaryngol 127:532-539.
    • (2007) Acta Otolaryngol , vol.127 , pp. 532-539
    • Kross, K.W.1    Heimdal, J.H.2    Olsnes, C.3    Olofson, J.4    Aarstad, H.J.5
  • 41
    • 0002325617 scopus 로고    scopus 로고
    • Interleukin 12: Basic biology and potential applications in cancer treatment
    • Robertson MJ, Ritz J (1996) Interleukin 12: basic biology and potential applications in cancer treatment. Oncologist 1:88-97.
    • (1996) Oncologist , vol.1 , pp. 88-97
    • Robertson, M.J.1    Ritz, J.2
  • 43
    • 0020196797 scopus 로고
    • Murine t cell subsets and interleukins: Relationships between cytotoxic t cells, helper t cells and accessory cells
    • Wagner H, Kronke M, Solbach W, Scheurich P, Rollinghoff M, et al. (1982) Murine t cell subsets and interleukins: relationships between cytotoxic t cells, helper t cells and accessory cells. Clin Haematol 11:607-630.
    • (1982) Clin Haematol , vol.11 , pp. 607-630
    • Wagner, H.1    Kronke, M.2    Solbach, W.3    Scheurich, P.4    Rollinghoff, M.5
  • 46
    • 27644457376 scopus 로고    scopus 로고
    • Tgf-β directly targets cytotoxic t cell functions during tumor evasion of immune surveillance
    • Thomas DA, Massagué J (2005) Tgf-β directly targets cytotoxic t cell functions during tumor evasion of immune surveillance. Cancer Cell 8:369-380.
    • (2005) Cancer Cell , vol.8 , pp. 369-380
    • Thomas, D.A.1    Massagué, J.2
  • 47
    • 62449179631 scopus 로고    scopus 로고
    • Granulocyte macrophage colony-stimulating factor inhibits breats growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages
    • Eubank TD, Roberts RD, Khan M, Curry JM, Nuovo GJ, et al. (2009) Granulocyte macrophage colony-stimulating factor inhibits breats growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages. Cancer Res 69:2133-2140.
    • (2009) Cancer Res , vol.69 , pp. 2133-2140
    • Eubank, T.D.1    Roberts, R.D.2    Khan, M.3    Curry, J.M.4    Nuovo, G.J.5
  • 48
    • 84871391940 scopus 로고    scopus 로고
    • Decreased plasma il-35 levels are related to the left ventricular ejection fraction in coronary artery diseases
    • Lin Y, Huang Y, Lu Z, Luo C, Shi Y, et al. (2012) Decreased plasma il-35 levels are related to the left ventricular ejection fraction in coronary artery diseases. PLoS ONE 7:e52490.
    • (2012) PLoS ONE , vol.7 , pp. e52490
    • Lin, Y.1    Huang, Y.2    Lu, Z.3    Luo, C.4    Shi, Y.5
  • 49
    • 45449094504 scopus 로고    scopus 로고
    • A methodology for performing global uncertaintly and sensitivity analysis in systems biology
    • Marino S, Hogue IB, Ray CJ, Kirschner DE (2008) A methodology for performing global uncertaintly and sensitivity analysis in systems biology. J Theor Biol 254:178-196.
    • (2008) J Theor Biol , vol.254 , pp. 178-196
    • Marino, S.1    Hogue, I.B.2    Ray, C.J.3    Kirschner, D.E.4
  • 50
    • 84908390756 scopus 로고    scopus 로고
    • Il-35 promotes pancreas cancer growth through enhancement of proliferation and inhibition of apoptosis: Evidence for a role as an autocrine growth factor
    • in press
    • Nicholl MB, Ledgewood CL, Chen X, Bai Q, Qin C, et al. (2014) Il-35 promotes pancreas cancer growth through enhancement of proliferation and inhibition of apoptosis: Evidence for a role as an autocrine growth factor. Cytokine: in press.
    • (2014) Cytokine
    • Nicholl, M.B.1    Ledgewood, C.L.2    Chen, X.3    Bai, Q.4    Qin, C.5
  • 54
    • 84871173673 scopus 로고    scopus 로고
    • Il-10 produced by induced regulatory t cells (itregs) controls colitis and pathogenic exitregs during immunotherapy
    • Schmitt EG, Haribhai D, Williams JB, Aggarwal P, Jia S, et al. (2012) Il-10 produced by induced regulatory t cells (itregs) controls colitis and pathogenic exitregs during immunotherapy. J Immunol 189:5638-5648.
    • (2012) J Immunol , vol.189 , pp. 5638-5648
    • Schmitt, E.G.1    Haribhai, D.2    Williams, J.B.3    Aggarwal, P.4    Jia, S.5
  • 55
    • 84867995078 scopus 로고    scopus 로고
    • Hypoxia inducible factors mediate the inhibtion of cancer by gm-csf: A mathematical model
    • Chen D, Roda JM, Marsh CB, Eubank TD, Friedman A (2012) Hypoxia inducible factors mediate the inhibtion of cancer by gm-csf: a mathematical model. Bull Math Biol 17:2752-2777.
    • (2012) Bull Math Biol , vol.17 , pp. 2752-2777
    • Chen, D.1    Roda, J.M.2    Marsh, C.B.3    Eubank, T.D.4    Friedman, A.5
  • 56
    • 84876435186 scopus 로고    scopus 로고
    • The role of cd200-cd200r in tumor immune evasion
    • Liao KL, Bai XF, Friedman A (2013) The role of cd200-cd200r in tumor immune evasion. J Theor Biol 328:65-76.
    • (2013) J Theor Biol , vol.328 , pp. 65-76
    • Liao, K.L.1    Bai, X.F.2    Friedman, A.3
  • 57
    • 3042713269 scopus 로고    scopus 로고
    • A mathematical model of tumor anglogenesis, regulated by vascular endothelial growth factor and the angiopoietins
    • Plank MJ, Sleeman BD, Jones PF (2004) A mathematical model of tumor anglogenesis, regulated by vascular endothelial growth factor and the angiopoietins. J Theore Biol 229:435-454.
    • (2004) J Theore Biol , vol.229 , pp. 435-454
    • Plank, M.J.1    Sleeman, B.D.2    Jones, P.F.3
  • 58
    • 67650433616 scopus 로고    scopus 로고
    • Modeling the immune rheostat of macrophages in the lung in response to infection
    • Day J, Friedman A, Schlesinger LS (2008) Modeling the immune rheostat of macrophages in the lung in response to infection. PNAS 106:11246-11251.
    • (2008) PNAS , vol.106 , pp. 11246-11251
    • Day, J.1    Friedman, A.2    Schlesinger, L.S.3
  • 59
    • 0033567908 scopus 로고    scopus 로고
    • Behavior and therapeutic efficacy of β-glucuronidase-positive mononuclear phagocytes in murine model of mucopolysaccharidosis type vii
    • Freeman BJ, Roberts MS, Vogler CA, Nicholes A, Hofling AA, et al. (1999) Behavior and therapeutic efficacy of β-glucuronidase-positive mononuclear phagocytes in murine model of mucopolysaccharidosis type vii. Blood 94:2142-2150.
    • (1999) Blood , vol.94 , pp. 2142-2150
    • Freeman, B.J.1    Roberts, M.S.2    Vogler, C.A.3    Nicholes, A.4    Hofling, A.A.5
  • 60
    • 57349100395 scopus 로고    scopus 로고
    • A simple mathematical model of cytokine capture using a hemoadsorption device
    • DiLeo MV, Kellum JA, Federspiel WJ (2009) A simple mathematical model of cytokine capture using a hemoadsorption device. Ann Biomed Eng 37:222-229.
    • (2009) Ann Biomed Eng , vol.37 , pp. 222-229
    • DiLeo, M.V.1    Kellum, J.A.2    Federspiel, W.J.3
  • 62
    • 0345608301 scopus 로고
    • Decreased interleukin-12 (il-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of interferongamma, natural killer, and lyphokine-activated killer activity by il-12 in cord blood mononuclear cells
    • Lee SM, Suen Y, Chang L, Bruner V, Qian J, et al. (1995) Decreased interleukin-12 (il-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of interferongamma, natural killer, and lyphokine-activated killer activity by il-12 in cord blood mononuclear cells. Blood 88:945-954.
    • (1995) Blood , vol.88 , pp. 945-954
    • Lee, S.M.1    Suen, Y.2    Chang, L.3    Bruner, V.4    Qian, J.5
  • 63
    • 0032900383 scopus 로고    scopus 로고
    • Immunological effects of interleukin 12 administered by bolus intravenous injection to patients with cancer
    • Robertson MJ, Cameron C, Atkins MB, Gordon MS, Lotze MT, et al. (1999) Immunological effects of interleukin 12 administered by bolus intravenous injection to patients with cancer. Clin Cancer Res 5:9-16.
    • (1999) Clin Cancer Res , vol.5 , pp. 9-16
    • Robertson, M.J.1    Cameron, C.2    Atkins, M.B.3    Gordon, M.S.4    Lotze, M.T.5
  • 65
    • 33745016900 scopus 로고    scopus 로고
    • Scale-up of breast cancer stem cell aggregate cultures to suspension bioreactors
    • Youn BS, Sen A, Behie LA, Girgis-Gabardo A, Hassell JA (2008) Scale-up of breast cancer stem cell aggregate cultures to suspension bioreactors. Biotechnol Prog 22:801-810.
    • (2008) Biotechnol Prog , vol.22 , pp. 801-810
    • Youn, B.S.1    Sen, A.2    Behie, L.A.3    Girgis-Gabardo, A.4    Hassell, J.A.5
  • 66
    • 0035605450 scopus 로고    scopus 로고
    • Modeling the interactions between tumor cells and a blood vessel in a microenvironment within a vascular tumor
    • Breward CJW, Byrne HM, Lewis CE (2001) Modeling the interactions between tumor cells and a blood vessel in a microenvironment within a vascular tumor. European J Appl Math 12:529-556.
    • (2001) European J Appl Math , vol.12 , pp. 529-556
    • Breward, C.J.W.1    Byrne, H.M.2    Lewis, C.E.3
  • 67
    • 68749109536 scopus 로고    scopus 로고
    • A distinct macrophage population mediated metastatic breast cancer cell extravasation, establishment and growth
    • Qian B, Deng Y, Hong Im J, Muschel RJ, Zou Y, et al. (2009) A distinct macrophage population mediated metastatic breast cancer cell extravasation, establishment and growth. PLoS ONE 4:e6563.
    • (2009) PLoS ONE , vol.4 , pp. e6563
    • Qian, B.1    Deng, Y.2    Im, J.H.3    Muschel, R.J.4    Zou, Y.5
  • 68
    • 0345707572 scopus 로고    scopus 로고
    • Oxygenation gain factor: A novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers
    • Vaupel P, Mayer A, Briest S, Höckel M (2003) Oxygenation gain factor: a novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers. Cancer Res 63:7634-7637.
    • (2003) Cancer Res , vol.63 , pp. 7634-7637
    • Vaupel, P.1    Mayer, A.2    Briest, S.3    Höckel, M.4
  • 69
    • 0023777948 scopus 로고
    • Glucose diffusivity in multicellular tumor spheroids
    • Casciari JJ, Sotirchos SV, Sutherland RM (1988) Glucose diffusivity in multicellular tumor spheroids. Cancer Res 48:3905-3909.
    • (1988) Cancer Res , vol.48 , pp. 3905-3909
    • Casciari, J.J.1    Sotirchos, S.V.2    Sutherland, R.M.3
  • 70
    • 0031558747 scopus 로고    scopus 로고
    • Pattern formation and spatiotemporal irregularity in a model for macrophage tumor interactions
    • Owen MR, Sherratt JA (1998) Pattern formation and spatiotemporal irregularity in a model for macrophage tumor interactions. J Theore Biol 189:63-80.
    • (1998) J Theore Biol , vol.189 , pp. 63-80
    • Owen, M.R.1    Sherratt, J.A.2
  • 71
    • 0034880050 scopus 로고    scopus 로고
    • Association between serum macrophage colony-stimulating factor levels and monocyte and thrombocyte counts in healthy, hypoxic, and septic term neonates
    • Oren H, Duman N, Abacioglu H, Ozkan H, Irken G (2001) Association between serum macrophage colony-stimulating factor levels and monocyte and thrombocyte counts in healthy, hypoxic, and septic term neonates. Pediatrics 108:329-332.
    • (2001) Pediatrics , vol.108 , pp. 329-332
    • Oren, H.1    Duman, N.2    Abacioglu, H.3    Ozkan, H.4    Irken, G.5
  • 73
    • 0034480628 scopus 로고    scopus 로고
    • Internalization and halflife of membrane-bound macrophage colony-simulating factor
    • Tang S, Liu H, Chen G, Rao Q, Geng Y, et al. (2000) Internalization and halflife of membrane-bound macrophage colony-simulating factor. Chinese Sc Bull 45:1697-1703.
    • (2000) Chinese Sc Bull , vol.45 , pp. 1697-1703
    • Tang, S.1    Liu, H.2    Chen, G.3    Rao, Q.4    Geng, Y.5
  • 75
    • 33746743790 scopus 로고    scopus 로고
    • Cell death and the maintenance of immunological memory
    • Yates A, Callard R (2001) Cell death and the maintenance of immunological memory. Discret Contin Dyn S 1:43-59.
    • (2001) Discret Contin Dyn S , vol.1 , pp. 43-59
    • Yates, A.1    Callard, R.2
  • 76
    • 77954623323 scopus 로고    scopus 로고
    • Interaction of tumor with its micro-environment: A mathematical model
    • Kim Y, Friedman A (2010) Interaction of tumor with its micro-environment: a mathematical model. J Math Biol 72:1029-1068.
    • (2010) J Math Biol , vol.72 , pp. 1029-1068
    • Kim, Y.1    Friedman, A.2
  • 77
    • 1642407734 scopus 로고    scopus 로고
    • The human immune response to mycobacterium tuberculosis in lung and lymph node
    • Marino S, Kirschner DE (2004) The human immune response to mycobacterium tuberculosis in lung and lymph node. J Theor Biol 227:463-486.
    • (2004) J Theor Biol , vol.227 , pp. 463-486
    • Marino, S.1    Kirschner, D.E.2
  • 78
    • 0035877019 scopus 로고    scopus 로고
    • Peripheral blood fibrocytes: Differentiation pathway and migration to wound sites
    • Abe R, Donnelly SC, Peng T, Bucala R, Metz CN (2001) Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J Immunol 166:7556-7562.
    • (2001) J Immunol , vol.166 , pp. 7556-7562
    • Abe, R.1    Donnelly, S.C.2    Peng, T.3    Bucala, R.4    Metz, C.N.5
  • 79
    • 69249221370 scopus 로고    scopus 로고
    • A mathematical model for pattern formation of glioma cells outside the tumor spheroid core
    • Kim Y, Lawler S, Nowicki MO, Chiocca EA, Friedman A (2009) A mathematical model for pattern formation of glioma cells outside the tumor spheroid core. J Theore Biol 260:359-371.
    • (2009) J Theore Biol , vol.260 , pp. 359-371
    • Kim, Y.1    Lawler, S.2    Nowicki, M.O.3    Chiocca, E.A.4    Friedman, A.5
  • 80
    • 77954029740 scopus 로고    scopus 로고
    • Transfirmed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: A mathematical model and experiments
    • Kim Y, Wallace J, Li F, Ostrowski M, Friedman A (2010) Transfirmed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: a mathematical model and experiments. J Math Biol 61:401-421.
    • (2010) J Math Biol , vol.61 , pp. 401-421
    • Kim, Y.1    Wallace, J.2    Li, F.3    Ostrowski, M.4    Friedman, A.5
  • 81
    • 0033568304 scopus 로고    scopus 로고
    • Markers of lymphocyte homing distinguish cd4 t cell subsets that turn over in response to hiv-1 infection in humans
    • Hengel RL, Jones BM, Kennedy MS, Hubbard MR, McDougal JS (1999) Markers of lymphocyte homing distinguish cd4 t cell subsets that turn over in response to hiv-1 infection in humans. J Immunol 163:3539-3548.
    • (1999) J Immunol , vol.163 , pp. 3539-3548
    • Hengel, R.L.1    Jones, B.M.2    Kennedy, M.S.3    Hubbard, M.R.4    McDougal, J.S.5
  • 82
    • 0032550369 scopus 로고    scopus 로고
    • Turnover of cd4+ and cd8+ t lymphocytes in hiv-1 infection as measured by ki-67 antigen
    • Sachsenberg N, Perelson AS, Yerly S, Schockmel GA, Leduc D, et al. (1998) Turnover of cd4+ and cd8+ t lymphocytes in hiv-1 infection as measured by ki-67 antigen. J Exp Med 187:1295-1303.
    • (1998) J Exp Med , vol.187 , pp. 1295-1303
    • Sachsenberg, N.1    Perelson, A.S.2    Yerly, S.3    Schockmel, G.A.4    Leduc, D.5
  • 83
    • 0015693581 scopus 로고
    • Circulating T and B lymphocytes of the mouse. II. Lifespan
    • Sprent J, Basten A (1973) Circulating t and b lymphocytes of the mouse. ii. lifespan. Cell Immunol 7:40-59.
    • (1973) Cell Immunol , vol.7 , pp. 40-59
    • Sprent, J.1    Basten, A.2
  • 84
    • 0035253576 scopus 로고    scopus 로고
    • A model to predict cell-mediated immune regulatory mechanisms during human infection with mycobacterium tuberculosis
    • Wigginton JE, Kirschner D (2001) A model to predict cell-mediated immune regulatory mechanisms during human infection with mycobacterium tuberculosis. J Immunol 166:1951-1967.
    • (2001) J Immunol , vol.166 , pp. 1951-1967
    • Wigginton, J.E.1    Kirschner, D.2
  • 85
    • 0037442018 scopus 로고    scopus 로고
    • Persistence and turnover of antigen-specific cd4 t cells during chronic tuberculosis infection in the mouse
    • Winslow GM, Roberts AD, Blackman MA, Woodland DL (2003) Persistence and turnover of antigen-specific cd4 t cells during chronic tuberculosis infection in the mouse. J Immunol 170:2046-2052.
    • (2003) J Immunol , vol.170 , pp. 2046-2052
    • Winslow, G.M.1    Roberts, A.D.2    Blackman, M.A.3    Woodland, D.L.4
  • 86
    • 0345737075 scopus 로고    scopus 로고
    • Model of competitive binding of vascular endothelial growth factor and placental growth factor to vegf receptors on endothelial cells
    • Gabhann FM, Popel AS (2003) Model of competitive binding of vascular endothelial growth factor and placental growth factor to vegf receptors on endothelial cells. Am J Physiol Heart Circ Physiol 286:H153-H164.
    • (2003) Am J Physiol Heart Circ Physiol , vol.286 , pp. H153-H164
    • Gabhann, F.M.1    Popel, A.S.2
  • 87
    • 40649097554 scopus 로고    scopus 로고
    • Wound angiogenesis as a function of tissue oxygen tension: A mathematical model
    • Schugart RC, Friedman A, Zhao R, Sen CK (2008) Wound angiogenesis as a function of tissue oxygen tension: a mathematical model. PNAS 105:2628-2633.
    • (2008) PNAS , vol.105 , pp. 2628-2633
    • Schugart, R.C.1    Friedman, A.2    Zhao, R.3    Sen, C.K.4
  • 89
    • 10344251488 scopus 로고    scopus 로고
    • Gm-csf induces expression of soluble vegf receptor-1 from human monocytes and inhibits angiogenesis in mice
    • Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, et al. (2004) Gm-csf induces expression of soluble vegf receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity 21:831-842.
    • (2004) Immunity , vol.21 , pp. 831-842
    • Eubank, T.D.1    Roberts, R.2    Galloway, M.3    Wang, Y.4    Cohn, D.E.5
  • 90
    • 0029422302 scopus 로고
    • The mathematical modeling of tumour angiogenesis and invasion
    • Chaplain MAJ (1995) The mathematical modeling of tumour angiogenesis and invasion. Acta Biotheoret 43:387-402.
    • (1995) Acta Biotheoret , vol.43 , pp. 387-402
    • Chaplain, M.A.J.1
  • 91
    • 0014094766 scopus 로고
    • Effect of lysolecithin on oxygen uptake of tumor cells polymorphonuclear leucocytes lymphocytes and macrophages in vitro
    • Butterworth AE, Cater DB (1967) Effect of lysolecithin on oxygen uptake of tumor cells polymorphonuclear leucocytes lymphocytes and macrophages in vitro. Br J Cancer 21:373-389.
    • (1967) Br J Cancer , vol.21 , pp. 373-389
    • Butterworth, A.E.1    Cater, D.B.2
  • 92
    • 70349266564 scopus 로고    scopus 로고
    • Oxygen consumption can regulate the growth of tumors, a new perspective on the warburg effect
    • Chen Y, Cairns R, Papandreou I, Koong A, Denko NC (2009) Oxygen consumption can regulate the growth of tumors, a new perspective on the warburg effect. PLoS ONE 4:e7033.
    • (2009) PLoS ONE , vol.4 , pp. e7033
    • Chen, Y.1    Cairns, R.2    Papandreou, I.3    Koong, A.4    Denko, N.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.