Enhanced gene delivery efficiency of cationic liposomes coated with PEGylated hyaluronic acid for anti P-glycoprotein siRNA: A potential candidate for overcoming multi-drug resistance

International Journal of Pharmaceutics

Volumn 477, Issue 1-2, 2014, Pages 590-600

  Ran, Rui ^a   Liu, Yayuan ^a   Gao, Huile ^a   Kuang, Qifang ^a   Zhang, Qianyu ^a   Tang, Jie ^a   Huang, Kai ^a   Chen, Xiaoxiao ^a   Zhang, Zhirong ^a   He, Qin ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Cationic liposome; P glycoprotein downregulation; PEGylated hyaluronic acid; siRNA delivery; Tumor targeting delivery

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; COPOLYMER; HYALURONIC ACID; LIPOFECTAMINE; LIPOSOME; MACROGOL 2000; MULTIDRUG RESISTANCE PROTEIN; NANOPARTICLE; NINHYDRIN; PROTAMINE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; MOUSE; NONHUMAN; PARTICLE SIZE; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; STATIC ELECTRICITY; SURFACE CHARGE; SYNTHESIS; ZETA POTENTIAL;

EID: 84910011417     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.11.012     Document Type: Article

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