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Volumn , Issue , 2014, Pages 257-278

Macrolides and ketolides

Author keywords

AUC MIC; K tolides; Macrolides; Tissue distribution

Indexed keywords


EID: 84910010052     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-75613-4_11     Document Type: Chapter
Times cited : (5)

References (135)
  • 1
    • 24044432916 scopus 로고    scopus 로고
    • Comparative pharmacodynamics of telithromycin and clarithromycin with streptococcus pneumoniae and staphylococcus aureus in an in vitro dynamic model: Focus on clinically achievable antibiotic concentrations
    • Alferova I.V., Vostrov SN, Portnoy YA et al (2005) Comparative pharmacodynamics of telithromycin and clarithromycin with Streptococcus pneumoniae and Staphylococcus aureus in an in vitro dynamic model: focus on clinically achievable antibiotic concentrations. Int J Antimicrob Agents 26:197-204
    • (2005) Int J Antimicrob Agents , vol.26 , pp. 197-204
    • Alferova, I.V.1    Vostrov, S.N.2    Portnoy, Y.A.3
  • 2
    • 33845696211 scopus 로고    scopus 로고
    • Pharmacokinetics-pharmacodynamics of antimicrobial therapy: It's not just for mice anymore
    • Ambrose PG, Bhavnani SM, Rubino CM et al (2007) Pharmacokinetics-pharmacodynamics of antimicrobial therapy: it's not just for mice anymore. Clin Infect Dis 44:79-86
    • (2007) Clin Infect Dis , vol.44 , pp. 79-86
    • Ambrose, P.G.1    Bhavnani, S.M.2    Rubino, C.M.3
  • 3
    • 0002078065 scopus 로고    scopus 로고
    • Advanced-generation macrolides: Tissue-directed antibiotics
    • Amsden GW (2001) Advanced-generation macrolides: tissue-directed antibiotics. Int J Antimicrob Agents 18(Suppl 1):S11-S15
    • (2001) Int J Antimicrob Agents , vol.18 , pp. S11-S15
    • Amsden, G.W.1
  • 4
    • 0032958771 scopus 로고    scopus 로고
    • Pharmacokinetics in serum and leukocyte exposures of oral azithromycin, 1,500 milligrams, given over a 3- or 5-day period in healthy subjects
    • Amsden GW, Nafziger AN, Foulds G. (1999) Pharmacokinetics in serum and leukocyte exposures of oral azithromycin, 1,500 milligrams, given over a 3- or 5-day period in healthy subjects. Antimicrob Agents Chemother 43:163-165
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 163-165
    • Amsden, G.W.1    Nafziger, A.N.2    Foulds, G.3
  • 5
    • 85039708793 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic (PK-PD) analysis of solithromycin against streptococcus pneumoniae using data from a murine-lung infection model
    • Boston, MA A1-688
    • Andes DR, Okusanya OO, Forrest A et al (2010) Pharmacokinetic-pharmacodynamic (PK-PD) analysis of Solithromycin against Streptococcus pneumoniae using data from a murine-lung infection model. In: 50th Interscience conference on antimicrobial agents and chemotherapy (ICAAC), Boston, MA A1-688
    • (2010) 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
    • Andes, D.R.1    Okusanya, O.O.2    Forrest, A.3
  • 6
    • 0026558750 scopus 로고
    • The new macrolide antibiotics: Azithromycin, clarithromycin, dirithromycin, and roxithromycin
    • Bahal N, Nahata M.C. (1992) The new macrolide antibiotics: azithromycin, clarithromycin, dirithromycin, and roxithromycin. Ann Pharmacother 26:46-55
    • (1992) Ann Pharmacother , vol.26 , pp. 46-55
    • Bahal, N.1    Nahata, M.C.2
  • 7
    • 33644656768 scopus 로고    scopus 로고
    • Pharmacodynamic evaluation of the intracellular activities of antibiotics against staphylococcus aureus in a model of THP-1 macrophages
    • Barcia-Macay M., Seral C, Mingeot-Leclercq MP et al (2006) Pharmacodynamic evaluation of the intracellular activities of antibiotics against Staphylococcus aureus in a model of THP-1 macrophages. Antimicrob Agents Chemother 50:841-851
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 841-851
    • Barcia-Macay, M.1    Seral, C.2    Mingeot-Leclercq, M.P.3
  • 9
    • 0027992703 scopus 로고
    • Azithromycin uptake and intracellular accumulation by toxoplasma gondii-infected macrophages
    • Blais J, Beauchamp D, Chamberland S. (1994) Azithromycin uptake and intracellular accumulation by Toxoplasma gondii-infected macrophages. J Antimicrob Chemother 34:371-382
    • (1994) J Antimicrob Chemother , vol.34 , pp. 371-382
    • Blais, J.1    Beauchamp, D.2    Chamberland, S.3
  • 10
    • 19544366269 scopus 로고    scopus 로고
    • Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin
    • Bosnar M, Kelneric Z, Munic V et al (2005) Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin. Antimicrob Agents Chemother 49: 2372-2377
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2372-2377
    • Bosnar, M.1    Kelneric, Z.2    Munic, V.3
  • 11
    • 0031942015 scopus 로고    scopus 로고
    • Pharmacodynamic properties of HMR 3647, a novel ketolide, on respiratory pathogens, enterococci and bacteroides fragilis demonstrated by studies of time-kill kinetics and postantibiotic effect
    • Boswell FJ, Andrews JM, Wise R. (1998) Pharmacodynamic properties of HMR 3647, a novel ketolide, on respiratory pathogens, enterococci and Bacteroides fragilis demonstrated by studies of time-kill kinetics and postantibiotic effect. J Antimicrob Chemother 41:149-153
    • (1998) J Antimicrob Chemother , vol.41 , pp. 149-153
    • Boswell, F.J.1    Andrews, J.M.2    Wise, R.3
  • 12
    • 0023711888 scopus 로고
    • Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-AZA-9a-homoerythromycin A derivatives; a new class of macrolide antibiotics, the azalides
    • Bright GM, Nagel AA, Bordner J et al (1988) Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-AZA-9a-homoerythromycin A derivatives; a new class of macrolide antibiotics, the azalides. J Antibiot (Tokyo) 41:1029-1047
    • (1988) J Antibiot (Tokyo) , vol.41 , pp. 1029-1047
    • Bright, G.M.1    Nagel, A.A.2    Bordner, J.3
  • 13
    • 0028598827 scopus 로고
    • Dirithromycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic efficacy
    • Brogden RN, Peters D.H. (1994) Dirithromycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic efficacy. Drugs 48:599-616
    • (1994) Drugs , vol.48 , pp. 599-616
    • Brogden, R.N.1    Peters, D.H.2
  • 14
    • 0034583884 scopus 로고    scopus 로고
    • Ketolides-telithromycin, an example of a new class of antibacterial agents
    • Bryskier A (2000) Ketolides-telithromycin, an example of a new class of antibacterial agents. Clin Microbiol Infect 6:661-669
    • (2000) Clin Microbiol Infect , vol.6 , pp. 661-669
    • Bryskier, A.1
  • 15
    • 0031857650 scopus 로고    scopus 로고
    • Pharmacodynamics of macrolides, azalides, and streptogramins: Effect on extracellular pathogens
    • Carbon C (1998) Pharmacodynamics of macrolides, azalides, and streptogramins: effect on extracellular pathogens. Clin Infect Dis 27:28-32
    • (1998) Clin Infect Dis , vol.27 , pp. 28-32
    • Carbon, C.1
  • 16
    • 0023481181 scopus 로고
    • Cellular uptake and subcellular distribution of roxithromycin and erythromycin in phagocytic cells
    • Carlier MB, Zenebergh A, Tulkens P.M. (1987) Cellular uptake and subcellular distribution of roxithromycin and erythromycin in phagocytic cells. J Antimicrob Chemother 20(Suppl B): 47-56
    • (1987) J Antimicrob Chemother , vol.20 , pp. 47-56
    • Carlier, M.B.1    Zenebergh, A.2    Tulkens, P.M.3
  • 17
    • 0028672538 scopus 로고
    • Accumulation, release and subcellular localization of azithromycin in phagocytic and non-phagocytic cells in culture
    • Carlier MB, Garcia-Luque I, Montenez JP et al (1994) Accumulation, release and subcellular localization of azithromycin in phagocytic and non-phagocytic cells in culture. Int J Tissue React 16:211-220
    • (1994) Int J Tissue React , vol.16 , pp. 211-220
    • Carlier, M.B.1    Garcia-Luque, I.2    Montenez, J.P.3
  • 18
    • 0035984781 scopus 로고    scopus 로고
    • Comparative intracellular (THP-1 macrophage) and extracellular activities of beta-lactams, azithromycin, gentamicin, and fluoroquinolones against listeria monocytogenes at clinically relevant concentrations
    • Carryn S, Van Bambeke F, Mingeot-Leclercq MP et al (2002) Comparative intracellular (THP-1 macrophage) and extracellular activities of beta-lactams, azithromycin, gentamicin, and fluoroquinolones against Listeria monocytogenes at clinically relevant concentrations. Antimicrob Agents Chemother 46:2095-2103
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 2095-2103
    • Carryn, S.1    Van Bambeke, F.2    Mingeot-Leclercq, M.P.3
  • 20
    • 0022641835 scopus 로고
    • Antibacterial activity of roxithromycin: A laboratory evaluation
    • Chantot JF, Bryskier A, Gasc J.C. (1986) Antibacterial activity of roxithromycin: a laboratory evaluation. J Antibiot (Tokyo) 39:660-668
    • (1986) J Antibiot (Tokyo) , vol.39 , pp. 660-668
    • Chantot, J.F.1    Bryskier, A.2    Gasc, J.C.3
  • 21
    • 4344607954 scopus 로고    scopus 로고
    • Steady-state plasma and intrapulmonary pharmacokinetics and pharmacodynamics of cethromycin
    • Conte JE J.r., Golden JA, Kipps J et al (2004) Steady-state plasma and intrapulmonary pharmacokinetics and pharmacodynamics of cethromycin. Antimicrob Agents Chemother 48:3508-3515
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3508-3515
    • Conte, J.E.1    Golden, J.A.2    Kipps, J.3
  • 22
    • 0031952586 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic parameters: Rationale for antibacterial dosing of mice and men
    • Craig WA (1998) Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 26:1-10
    • (1998) Clin Infect Dis , vol.26 , pp. 1-10
    • Craig, W.A.1
  • 23
    • 0038372082 scopus 로고    scopus 로고
    • Free drug 24-hr AUC/MIC is the PK/PD target that correlates with in vivo efficacy of macrolides, azalides, ketolides and clindamycin
    • San Diego, CA A-1264
    • Craig WA, Kiem S, Andes D.R. (2002) Free drug 24-Hr AUC/MIC is the PK/PD target that correlates with in vivo efficacy of macrolides, azalides, ketolides and clindamycin. In: 42d Interscience conference on antimicrobial agents and chemotherapy, San Diego, CA A-1264
    • (2002) 42d Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Craig, W.A.1    Kiem, S.2    Andes, D.R.3
  • 25
    • 0033229837 scopus 로고    scopus 로고
    • Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens
    • Denis A, Agouridas C, Auger JM et al (1999) Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. Bioorg Med Chem Lett 9:3075-3080
    • (1999) Bioorg Med Chem Lett , vol.9 , pp. 3075-3080
    • Denis, A.1    Agouridas, C.2    Auger, J.M.3
  • 26
    • 0036449979 scopus 로고    scopus 로고
    • Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily
    • Di Paolo A., Barbara C, Chella A et al (2002) Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily. Pharmacol Res 46:545-550
    • (2002) Pharmacol Res , vol.46 , pp. 545-550
    • Di Paolo, A.1    Barbara, C.2    Chella, A.3
  • 27
    • 0023212808 scopus 로고
    • Erythromycin series. XII. Antibacterial in vitro evaluation of 10-dihydro-10-deoxo-11-azaerythromycin A: Synthesis and structure-activity relationship of its acyl derivatives
    • Djokic S, Kobrehel G, Lazarevski G. (1987) Erythromycin series. XII. Antibacterial in vitro evaluation of 10-dihydro-10-deoxo-11-azaerythromycin A: synthesis and structure-activity relationship of its acyl derivatives. J Antibiot (Tokyo) 40:1006-1015
    • (1987) J Antibiot (Tokyo) , vol.40 , pp. 1006-1015
    • Djokic, S.1    Kobrehel, G.2    Lazarevski, G.3
  • 28
    • 0032908483 scopus 로고    scopus 로고
    • Postantibiotic effect and postantibiotic sub-mic effect of dirithromycin and erythromycin against respiratory tract pathogenic bacteria
    • Dornbusch K, Olofsson C, Holm S. (1999) Postantibiotic effect and postantibiotic sub-mic effect of dirithromycin and erythromycin against respiratory tract pathogenic bacteria. APMIS 107:505-513
    • (1999) APMIS , vol.107 , pp. 505-513
    • Dornbusch, K.1    Olofsson, C.2    Holm, S.3
  • 29
    • 0035224671 scopus 로고    scopus 로고
    • Structure-activity relationships of ketolides vs. Macrolides
    • Douthwaite S (2001) Structure-activity relationships of ketolides vs. macrolides. Clin Microbiol Infect 7(Suppl 3):11-17
    • (2001) Clin Microbiol Infect , vol.7 , pp. 11-17
    • Douthwaite, S.1
  • 30
    • 0034763651 scopus 로고    scopus 로고
    • Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site
    • Douthwaite S, Champney W.S. (2001) Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site. J Antimicrob Chemother 48 (Suppl T1):1-8
    • (2001) J Antimicrob Chemother , vol.48 , pp. 1-8
    • Douthwaite, S.1    Champney, W.S.2
  • 31
    • 28844462823 scopus 로고    scopus 로고
    • Kinetic bactericidal activity of telithromycin, azithromycin and clarithromycin against respiratory pathogens
    • Drago L, De Vecchi E, Nicola L et al (2005) Kinetic bactericidal activity of telithromycin, azithromycin and clarithromycin against respiratory pathogens. APMIS 113:655-663
    • (2005) APMIS , vol.113 , pp. 655-663
    • Drago, L.1    De Vecchi, E.2    Nicola, L.3
  • 32
    • 43549122049 scopus 로고    scopus 로고
    • Pharmacokinetics of azithromycin in serum and sinus fluid after administration of extended-release and immediate-release formulations in patients with acute bacterial sinusitis
    • Ehnhage A, Rautiainen M, Fang AF et al (2008) Pharmacokinetics of azithromycin in serum and sinus fluid after administration of extended-release and immediate-release formulations in patients with acute bacterial sinusitis. Int J Antimicrob Agents 31:561-566
    • (2008) Int J Antimicrob Agents , vol.31 , pp. 561-566
    • Ehnhage, A.1    Rautiainen, M.2    Fang, A.F.3
  • 33
    • 67349099518 scopus 로고    scopus 로고
    • Pharmacokinetics of azithromycin in plasma and sinus mucosal tissue following administration of extended-release or immediate-release formulations in adult patients with chronic rhinosinusitis
    • Fang AF, Palmer JN, Chiu AG et al (2009) Pharmacokinetics of azithromycin in plasma and sinus mucosal tissue following administration of extended-release or immediate-release formulations in adult patients with chronic rhinosinusitis. Int J Antimicrob Agents 34:67-71
    • (2009) Int J Antimicrob Agents , vol.34 , pp. 67-71
    • Fang, A.F.1    Palmer, J.N.2    Chiu, A.G.3
  • 34
    • 0022982303 scopus 로고
    • In vitro and in vivo evaluation of A-56268 (TE-031), a new macrolide
    • Fernandes PB, Bailer R, Swanson R et al (1986) In vitro and in vivo evaluation of A-56268 (TE-031), a new macrolide. Antimicrob Agents Chemother 30:865-873
    • (1986) Antimicrob Agents Chemother , vol.30 , pp. 865-873
    • Fernandes, P.B.1    Bailer, R.2    Swanson, R.3
  • 35
    • 0036151472 scopus 로고    scopus 로고
    • Comparative pharmacodynamics of azithromycin and roxithromycin with S. Pyogenes and S. Pneumoniae in a model that simulates in vitro pharmacokinetics in human tonsils
    • Firsov AA, Zinner SH, Vostrov SN et al (2002) Comparative pharmacodynamics of azithromycin and roxithromycin with S. pyogenes and S. pneumoniae in a model that simulates in vitro pharmacokinetics in human tonsils. J Antimicrob Chemother 49:113-119
    • (2002) J Antimicrob Chemother , vol.49 , pp. 113-119
    • Firsov, A.A.1    Zinner, S.H.2    Vostrov, S.N.3
  • 36
    • 0025096817 scopus 로고
    • The pharmacokinetics of azithromycin in human serum and tissues
    • Foulds G, Shepard RM, Johnson R.B. (1990) The pharmacokinetics of azithromycin in human serum and tissues. J Antimicrob Chemother 25(Suppl A):73-82
    • (1990) J Antimicrob Chemother , vol.25 , pp. 73-82
    • Foulds, G.1    Shepard, R.M.2    Johnson, R.B.3
  • 39
    • 0027999049 scopus 로고
    • Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid
    • Freeman CD, Nightingale CH, Nicolau DP et al (1994) Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid. Antimicrob Agents Chemother 38:2449-2451
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 2449-2451
    • Freeman, C.D.1    Nightingale, C.H.2    Nicolau, D.P.3
  • 40
    • 19244374949 scopus 로고
    • Macrolides: Present and future. An appraisal of in-vitro activity and pharmacokinetic behavior
    • Furneri PM, Nicoletti G. (1991) Macrolides: present and future. An appraisal of in-vitro activity and pharmacokinetic behavior. J Chemother 3(Suppl 1):24-27
    • (1991) J Chemother , vol.3 , pp. 24-27
    • Furneri, P.M.1    Nicoletti, G.2
  • 41
    • 75749085747 scopus 로고    scopus 로고
    • Intrapulmonary pharmacokinetics of S-013420, a novel bicyclolide antibacterial, in healthy Japanese subjects
    • Furuie H, Saisho Y, Yoshikawa T et al (2010) Intrapulmonary pharmacokinetics of S-013420, a novel bicyclolide antibacterial, in healthy Japanese subjects. Antimicrob Agents Chemother 54:866-870
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 866-870
    • Furuie, H.1    Saisho, Y.2    Yoshikawa, T.3
  • 42
    • 0038601497 scopus 로고    scopus 로고
    • Accumulation and activity of cethromycin (ABT-773) within human polymorphonuclear leucocytes
    • Garcia I, Pascual A, Ballesta S et al (2003) Accumulation and activity of cethromycin (ABT-773) within human polymorphonuclear leucocytes. J Antimicrob Chemother 52:24-28
    • (2003) J Antimicrob Chemother , vol.52 , pp. 24-28
    • Garcia, I.1    Pascual, A.2    Ballesta, S.3
  • 43
    • 9644254238 scopus 로고    scopus 로고
    • Pharmacokinetics of telithromycin in plasma and soft tissues after single-dose administration to healthy volunteers
    • Gattringer R, Urbauer E, Traunmuller F et al (2004) Pharmacokinetics of telithromycin in plasma and soft tissues after single-dose administration to healthy volunteers. Antimicrob Agents Chemother 48:4650-4653
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 4650-4653
    • Gattringer, R.1    Urbauer, E.2    Traunmuller, F.3
  • 44
    • 0037405968 scopus 로고    scopus 로고
    • Telithromycin (HMR 3647) achieves high and sustained concentrations in tonsils of patients undergoing tonsillectomy
    • Gehanno P, Sultan E, Passot V et al (2003) Telithromycin (HMR 3647) achieves high and sustained concentrations in tonsils of patients undergoing tonsillectomy. Int J Antimicrob Agents 21: 441-445
    • (2003) Int J Antimicrob Agents , vol.21 , pp. 441-445
    • Gehanno, P.1    Sultan, E.2    Passot, V.3
  • 45
    • 0025101797 scopus 로고
    • Correlation of the extravascular pharmacokinetics of azithromycin with in-vivo efficacy in models of localized infection
    • Girard AE, Girard D, Retsema J.A. (1990) Correlation of the extravascular pharmacokinetics of azithromycin with in-vivo efficacy in models of localized infection. J Antimicrob Chemother 25(Suppl A):61-71
    • (1990) J Antimicrob Chemother , vol.25 , pp. 61-71
    • Girard, A.E.1    Girard, D.2    Retsema, J.A.3
  • 46
    • 0024522884 scopus 로고
    • In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: Possible mechanism of delivery and release at sites of infection
    • Gladue RP, Bright GM, Isaacson RE et al (1989) In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: possible mechanism of delivery and release at sites of infection. Antimicrob Agents Chemother 33:277-282
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 277-282
    • Gladue, R.P.1    Bright, G.M.2    Isaacson, R.E.3
  • 47
    • 0141741181 scopus 로고    scopus 로고
    • Steady-state plasma and bronchopulmonary characteristics of clarithromycin extended-release tablets in normal healthy adult subjects
    • Gotfried MH, Danziger LH, Rodvold K.A. (2003) Steady-state plasma and bronchopulmonary characteristics of clarithromycin extended-release tablets in normal healthy adult subjects. J Antimicrob Chemother 52:450-456
    • (2003) J Antimicrob Chemother , vol.52 , pp. 450-456
    • Gotfried, M.H.1    Danziger, L.H.2    Rodvold, K.A.3
  • 48
    • 0035022075 scopus 로고    scopus 로고
    • Pharmacokinetics and tolerability of extendedrelease clarithromycin
    • Guay DR, Gustavson LE, Devcich KJ et al (2001) Pharmacokinetics and tolerability of extendedrelease clarithromycin. Clin Ther 23:566-577
    • (2001) Clin Ther , vol.23 , pp. 566-577
    • Guay, D.R.1    Gustavson, L.E.2    Devcich, K.J.3
  • 49
    • 0035174343 scopus 로고    scopus 로고
    • Characteristics and mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes
    • Hand WL, Hand D.L. (2001) Characteristics and mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes. Int J Antimicrob Agents 18:419-425
    • (2001) Int J Antimicrob Agents , vol.18 , pp. 419-425
    • Hand, W.L.1    Hand, D.L.2
  • 50
    • 0037308582 scopus 로고    scopus 로고
    • Influence of macrolide susceptibility on efficacies of clarithromycin and azithromycin against streptococcus pneumoniae in a murine lung infection model
    • Hoffman HL, Klepser ME, Ernst EJ et al (2003) Influence of macrolide susceptibility on efficacies of clarithromycin and azithromycin against Streptococcus pneumoniae in a murine lung infection model. Antimicrob Agents Chemother 47:739-746
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 739-746
    • Hoffman, H.L.1    Klepser, M.E.2    Ernst, E.J.3
  • 51
    • 77957340321 scopus 로고    scopus 로고
    • In vitro pharmacokinetic and pharmacodynamic evaluation of S-013420 against haemophilus influenzae and streptococcus pneumoniae
    • Homma T, Hori T, Ohshiro M et al (2010) In vitro pharmacokinetic and pharmacodynamic evaluation of S-013420 against Haemophilus influenzae and Streptococcus pneumoniae. Antimicrob Agents Chemother 54:4300-4305
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4300-4305
    • Homma, T.1    Hori, T.2    Ohshiro, M.3
  • 52
    • 0020672034 scopus 로고
    • Intracellular multiplication of legionnaires' disease bacteria (Legionella pneumophila) in human monocytes is reversibly inhibited by erythromycin and rifampin
    • Horwitz MA, Silverstein S.C. (1983) Intracellular multiplication of Legionnaires' disease bacteria (Legionella pneumophila) in human monocytes is reversibly inhibited by erythromycin and rifampin. J Clin Invest 71:15-26
    • (1983) J Clin Invest , vol.71 , pp. 15-26
    • Horwitz, M.A.1    Silverstein, S.C.2
  • 54
    • 66149102781 scopus 로고    scopus 로고
    • Pharmacokinetics of EDP-420 after ascending single oral doses in healthy adult volunteers
    • Jiang LJ, Wang M, Or Y.S. (2009) Pharmacokinetics of EDP-420 after ascending single oral doses in healthy adult volunteers. Antimicrob Agents Chemother 53:1786-1792
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 1786-1792
    • Jiang, L.J.1    Wang, M.2    Or, Y.S.3
  • 55
    • 0036168517 scopus 로고    scopus 로고
    • Intrapulmonary pharmacokinetics of telithromycin, a new ketolide, in healthy Japanese volunteers
    • Kadota J, Ishimatsu Y, Iwashita T et al (2002) Intrapulmonary pharmacokinetics of telithromycin, a new ketolide, in healthy Japanese volunteers. Antimicrob Agents Chemother 46:917-921
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 917-921
    • Kadota, J.1    Ishimatsu, Y.2    Iwashita, T.3
  • 56
    • 0017262117 scopus 로고
    • Evaluation of midecamycin sensitivity disc (author's transl)
    • Kanazawa Y, Kuramata T. (1976) Evaluation of midecamycin sensitivity disc (author's transl). Jpn J Antibiot 29:178-183
    • (1976) Jpn J Antibiot , vol.29 , pp. 178-183
    • Kanazawa, Y.1    Kuramata, T.2
  • 57
    • 0019824634 scopus 로고
    • In vitro and in vivo antibacterial activity of 9,3''-di-oacetyl midecamycin (Mom), a new macrolide antibiotic
    • Kawaharajo K, Sekizawa Y, Inoue M. (1981) In vitro and in vivo antibacterial activity of 9,3''-Di-oacetyl midecamycin (Mom), a new macrolide antibiotic. J Antibiot (Tokyo) 34:436-442
    • (1981) J Antibiot (Tokyo) , vol.34 , pp. 436-442
    • Kawaharajo, K.1    Sekizawa, Y.2    Inoue, M.3
  • 58
    • 33846972314 scopus 로고    scopus 로고
    • Comparative in vitro and bactericidal activities of telithromycin against penicillin-nonsusceptible, levofloxacin-resistant, and macrolide-resistant streptococcus pneumoniae by time-kill methodology
    • Kays MB, Lisek CR, Denys G.A. (2007) Comparative in vitro and bactericidal activities of telithromycin against penicillin-nonsusceptible, levofloxacin-resistant, and macrolide-resistant Streptococcus pneumoniae by time-kill methodology. Int J Antimicrob Agents 29:289-294
    • (2007) Int J Antimicrob Agents , vol.29 , pp. 289-294
    • Kays, M.B.1    Lisek, C.R.2    Denys, G.A.3
  • 59
    • 0032723696 scopus 로고    scopus 로고
    • The penetration of anti-infectives into the central nervous system
    • Kearney BP, Aweeka F.T. (1999) The penetration of anti-infectives into the central nervous system. Neurol Clin 17:883-900
    • (1999) Neurol Clin , vol.17 , pp. 883-900
    • Kearney, B.P.1    Aweeka, F.T.2
  • 60
    • 77049232657 scopus 로고
    • Spiramycin in the treatment of infection
    • Kellow WF, Lepper MH, Plauts S et al (1955) Spiramycin in the treatment of infection. Antibiot Annu 3:658-666
    • (1955) Antibiot Annu , vol.3 , pp. 658-666
    • Kellow, W.F.1    Lepper, M.H.2    Plauts, S.3
  • 62
    • 40749140314 scopus 로고    scopus 로고
    • Pharmacokinetics of clarithromycin in bronchial epithelial lining fluid
    • Kikuchi E, Yamazaki K, Kikuchi J et al (2008) Pharmacokinetics of clarithromycin in bronchial epithelial lining fluid. Respirology 13:221-226
    • (2008) Respirology , vol.13 , pp. 221-226
    • Kikuchi, E.1    Yamazaki, K.2    Kikuchi, J.3
  • 63
    • 0036784365 scopus 로고    scopus 로고
    • Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model
    • Kim MK, Zhou W, Tessier PR et al (2002) Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model. Antimicrob Agents Chemother 46:3185-3192
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3185-3192
    • Kim, M.K.1    Zhou, W.2    Tessier, P.R.3
  • 64
    • 0024435166 scopus 로고
    • New directions for macrolide antibiotics: Structural modifications and in vitro activity
    • Kirst HA, Sides G.D. (1989) New directions for macrolide antibiotics: structural modifications and in vitro activity. Antimicrob Agents Chemother 33:1413-1418
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 1413-1418
    • Kirst, H.A.1    Sides, G.D.2
  • 65
    • 17444411576 scopus 로고    scopus 로고
    • Penetration of telithromycin into the nasal mucosa and ethmoid bone of patients undergoing rhinosurgery for chronic sinusitis
    • Kuehnel TS, Schurr C, Lotter K et al (2005) Penetration of telithromycin into the nasal mucosa and ethmoid bone of patients undergoing rhinosurgery for chronic sinusitis. J Antimicrob Chemother 55:591-594
    • (2005) J Antimicrob Chemother , vol.55 , pp. 591-594
    • Kuehnel, T.S.1    Schurr, C.2    Lotter, K.3
  • 66
    • 1642420415 scopus 로고    scopus 로고
    • Interaction of the new ketolide ABT-773 (cethromycin) with human polymorphonuclear neutrophils and the phagocytic cell line PLB-985 in vitro
    • Labro MT, Abdelghaffar H, Babin-Chevaye C (2004) Interaction of the new ketolide ABT-773 (cethromycin) with human polymorphonuclear neutrophils and the phagocytic cell line PLB-985 in vitro. Antimicrob Agents Chemother 48:1096-1104
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 1096-1104
    • Labro, M.T.1    Abdelghaffar, H.2    Babin-Chevaye, C.3
  • 67
  • 68
    • 70349153036 scopus 로고    scopus 로고
    • Cellular accumulation and pharmacodynamic evaluation of the intracellular activity of CEM-101, a novel fluoroketolide, against staphylococcus aureus, listeria monocytogenes, and legionella pneumophila in human THP-1 macrophages
    • Lemaire S, Van Bambeke F, Tulkens P.M. (2009) Cellular accumulation and pharmacodynamic evaluation of the intracellular activity of CEM-101, a novel fluoroketolide, against Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in human THP-1 macrophages. Antimicrob Agents Chemother 53:3734-3743
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3734-3743
    • Lemaire, S.1    Van Bambeke, F.2    Tulkens, P.M.3
  • 69
    • 23944472639 scopus 로고    scopus 로고
    • The bioequivalence of telithromycin administered orally as crushed tablets versus tablets swallowed whole
    • Lippert C, Gbenado S, Qiu C et al (2005) The bioequivalence of telithromycin administered orally as crushed tablets versus tablets swallowed whole. J Clin Pharmacol 45:1025-1031
    • (2005) J Clin Pharmacol , vol.45 , pp. 1025-1031
    • Lippert, C.1    Gbenado, S.2    Qiu, C.3
  • 70
    • 33846020066 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of azithromycin in serum and white blood cells of healthy subjects receiving a single-dose extended-release regimen versus a 3-day immediate-release regimen
    • Liu P, Allaudeen H, Chandra R et al (2007) Comparative pharmacokinetics of azithromycin in serum and white blood cells of healthy subjects receiving a single-dose extended-release regimen versus a 3-day immediate-release regimen. Antimicrob Agents Chemother 51:103-109
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 103-109
    • Liu, P.1    Allaudeen, H.2    Chandra, R.3
  • 71
    • 18844446241 scopus 로고    scopus 로고
    • Pharmacodynamics of an 800-mg dose of telithromycin in patients with community-acquired pneumonia caused by extracellular pathogens
    • Lodise TP, Preston S, Bhargava V et al (2005) Pharmacodynamics of an 800-mg dose of telithromycin in patients with community-acquired pneumonia caused by extracellular pathogens. Diagn Microbiol Infect Dis 52:45-52
    • (2005) Diagn Microbiol Infect Dis , vol.52 , pp. 45-52
    • Lodise, T.P.1    Preston, S.2    Bhargava, V.3
  • 72
    • 41149168759 scopus 로고    scopus 로고
    • Pharmacokinetics of azithromycin in serum, bronchial washings, alveolar macrophages and lung tissue following a single oral dose of extended or immediate release formulations of azithromycin
    • Lucchi M, Damle B, Fang A et al (2008) Pharmacokinetics of azithromycin in serum, bronchial washings, alveolar macrophages and lung tissue following a single oral dose of extended or immediate release formulations of azithromycin. J Antimicrob Chemother 61:884-891
    • (2008) J Antimicrob Chemother , vol.61 , pp. 884-891
    • Lucchi, M.1    Damle, B.2    Fang, A.3
  • 73
    • 0035016761 scopus 로고    scopus 로고
    • Uptake, transport, and delivery of antimicrobial agents by human polymorphonuclear neutrophils
    • Mandell GL, Coleman E. (2001) Uptake, transport, and delivery of antimicrobial agents by human polymorphonuclear neutrophils. Antimicrob Agents Chemother 45:1794-1798
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 1794-1798
    • Mandell, G.L.1    Coleman, E.2
  • 75
    • 0016014585 scopus 로고
    • Antibacterial activity of 9(S)-erythromycylaminealdehyde condensation products
    • Massey EH, Kitchell BS, Martin LD et al (1974) Antibacterial activity of 9(S)-erythromycylaminealdehyde condensation products. J Med Chem 17:105-107
    • (1974) J Med Chem , vol.17 , pp. 105-107
    • Massey, E.H.1    Kitchell, B.S.2    Martin, L.D.3
  • 78
    • 0346102550 scopus 로고    scopus 로고
    • Penetration of oral telithromycin into female genital tissues
    • Mikamo H, Ninomiya M, Tamaya T. (2003) Penetration of oral telithromycin into female genital tissues. J Infect Chemother 9:358-360
    • (2003) J Infect Chemother , vol.9 , pp. 358-360
    • Mikamo, H.1    Ninomiya, M.2    Tamaya, T.3
  • 79
    • 0033047391 scopus 로고    scopus 로고
    • Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [Dirithromycin], and azithromycin) with phospholipids: Computer-aided conformational analysis and studies on acellular and cell culture models
    • Montenez JP, Van Bambeke F, Piret J et al (1999) Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [Dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models. Toxicol Appl Pharmacol 156:129-140
    • (1999) Toxicol Appl Pharmacol , vol.156 , pp. 129-140
    • Montenez, J.P.1    Van Bambeke, F.2    Piret, J.3
  • 80
    • 0028144375 scopus 로고
    • Accumulation of clarithromycin in macrophages infected with mycobacterium avium
    • Mor N, Vanderkolk J, Heifets L. (1994) Accumulation of clarithromycin in macrophages infected with Mycobacterium avium. Pharmacotherapy 14:100-104
    • (1994) Pharmacotherapy , vol.14 , pp. 100-104
    • Mor, N.1    Vanderkolk, J.2    Heifets, L.3
  • 81
    • 0021329213 scopus 로고
    • Chemical modification of erythromycins. I. Synthesis and antibacterial activity of 6-O-methylerythromycins A
    • Morimoto S, Takahashi Y, Watanabe Y et al (1984) Chemical modification of erythromycins. I. Synthesis and antibacterial activity of 6-O-methylerythromycins A. J Antibiot (Tokyo) 37: 187-189
    • (1984) J Antibiot (Tokyo) , vol.37 , pp. 187-189
    • Morimoto, S.1    Takahashi, Y.2    Watanabe, Y.3
  • 82
    • 0034774476 scopus 로고    scopus 로고
    • Bronchopulmonary disposition of the ketolide telithromycin (HMR 3647)
    • Muller-Serieys C., Soler P, Cantalloube C et al (2001) Bronchopulmonary disposition of the ketolide telithromycin (HMR 3647). Antimicrob Agents Chemother 45:3104-3108
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 3104-3108
    • Muller-Serieys, C.1    Soler, P.2    Cantalloube, C.3
  • 83
    • 77954761478 scopus 로고    scopus 로고
    • Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays
    • Munic V, Kelneric Z, Mikac L et al (2010) Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays. Eur J Pharm Sci 41:86-95
    • (2010) Eur J Pharm Sci , vol.41 , pp. 86-95
    • Munic, V.1    Kelneric, Z.2    Mikac, L.3
  • 84
    • 78650393871 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic analysis of azithromycin extended release in Japanese patients with common respiratory tract infectious disease
    • Muto C, Liu P, Chiba K et al (2011) Pharmacokinetic-pharmacodynamic analysis of azithromycin extended release in Japanese patients with common respiratory tract infectious disease. J Antimicrob Chemother 66:165-174
    • (2011) J Antimicrob Chemother , vol.66 , pp. 165-174
    • Muto, C.1    Liu, P.2    Chiba, K.3
  • 85
    • 0035169214 scopus 로고    scopus 로고
    • Pharmacokinetics of the new ketolide telithromycin (HMR 3647) administered in ascending single and multiple doses
    • Namour F, Wessels DH, Pascual MH et al (2001) Pharmacokinetics of the new ketolide telithromycin (HMR 3647) administered in ascending single and multiple doses. Antimicrob Agents Chemother 45:170-175
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 170-175
    • Namour, F.1    Wessels, D.H.2    Pascual, M.H.3
  • 86
    • 0035992158 scopus 로고    scopus 로고
    • Penetration of telithromycin (HMR 3647), a new ketolide antimicrobial, into inflammatory blister fluid following oral administration
    • Namour F, Sultan E, Pascual MH et al (2002) Penetration of telithromycin (HMR 3647), a new ketolide antimicrobial, into inflammatory blister fluid following oral administration. J Antimicrob Chemother 49:1035-1038
    • (2002) J Antimicrob Chemother , vol.49 , pp. 1035-1038
    • Namour, F.1    Sultan, E.2    Pascual, M.H.3
  • 87
    • 0037417010 scopus 로고    scopus 로고
    • In vitro bactericidal activities of ABT-773 against ermB strains of streptococcus pneumoniae
    • Neuhauser MM, Prause JL, Danziger LH et al (2003) In vitro bactericidal activities of ABT-773 against ermB strains of Streptococcus pneumoniae. Antimicrob Agents Chemother 47:1132-1134
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1132-1134
    • Neuhauser, M.M.1    Prause, J.L.2    Danziger, L.H.3
  • 88
    • 0014112111 scopus 로고
    • A new antibiotic, josamycin. II. Biological studies
    • Nitta K, Yano K, Miyamoto F et al (1967) A new antibiotic, josamycin. II. Biological studies. J Antibiot (Tokyo) 20:181-187
    • (1967) J Antibiot (Tokyo) , vol.20 , pp. 181-187
    • Nitta, K.1    Yano, K.2    Miyamoto, F.3
  • 89
    • 0036894189 scopus 로고    scopus 로고
    • Pharmacodynamic modeling of clarithromycin against macrolide-resistant [PCR-positive mef(A) or erm(B)] streptococcus pneumoniae simulating clinically achievable serum and epithelial lining fluid free-drug concentrations
    • Noreddin AM, Roberts D, Nichol K et al (2002) Pharmacodynamic modeling of clarithromycin against macrolide-resistant [PCR-positive mef(A) or erm(B)] Streptococcus pneumoniae simulating clinically achievable serum and epithelial lining fluid free-drug concentrations. Antimicrob Agents Chemother 46:4029-4034
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 4029-4034
    • Noreddin, A.M.1    Roberts, D.2    Nichol, K.3
  • 90
    • 67349100212 scopus 로고    scopus 로고
    • Pharmacodynamic target attainment potential of azithromycin, clarithromycin, and telithromycin in serum and epithelial lining fluid of community-acquired pneumonia patients with penicillin-susceptible, intermediate, and resistant streptococcus pneumoniae
    • Noreddin AM, El Khatib WF, Aolie J et al (2009) Pharmacodynamic target attainment potential of azithromycin, clarithromycin, and telithromycin in serum and epithelial lining fluid of community-acquired pneumonia patients with penicillin-susceptible, intermediate, and resistant Streptococcus pneumoniae. Int J Infect Dis 13:483-487
    • (2009) Int J Infect Dis , vol.13 , pp. 483-487
    • Noreddin, A.M.1    El Khatib, W.F.2    Aolie, J.3
  • 91
    • 0035172060 scopus 로고    scopus 로고
    • Pharmacodynamics of telithromycin in vitro against respiratory tract pathogens
    • Odenholt I, Lowdin E, Cars O. (2001) Pharmacodynamics of telithromycin in vitro against respiratory tract pathogens. Antimicrob Agents Chemother 45:23-29
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 23-29
    • Odenholt, I.1    Lowdin, E.2    Cars, O.3
  • 92
    • 0028890069 scopus 로고
    • Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens
    • Odenholt-Tornqvist I., Lowdin E, Cars O. (1995) Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens. Antimicrob Agents Chemother 39:221-226
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 221-226
    • Odenholt-Tornqvist, I.1    Lowdin, E.2    Cars, O.3
  • 94
    • 0017164832 scopus 로고
    • Modifications of a macrolide antibiotic midecamycin (SF-837). I. Synthesis and structure of 9,3''-diacetylmidecamycin
    • Omoto S, Iwamatsu K, Inouye S et al (1976) Modifications of a macrolide antibiotic midecamycin (SF-837). I. Synthesis and structure of 9,3''-diacetylmidecamycin. J Antibiot (Tokyo) 29:536-548
    • (1976) J Antibiot (Tokyo) , vol.29 , pp. 536-548
    • Omoto, S.1    Iwamatsu, K.2    Inouye, S.3
  • 95
    • 0000184017 scopus 로고    scopus 로고
    • Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens
    • Or YS, Clark RF, Wang S et al (2000) Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens. J Med Chem 43:1045-1049
    • (2000) J Med Chem , vol.43 , pp. 1045-1049
    • Or, Y.S.1    Clark, R.F.2    Wang, S.3
  • 96
    • 0038725719 scopus 로고    scopus 로고
    • Experimental estimation of the role of P-glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the caco-2 cell model
    • Pachot JI, Botham RP, Haegele KD et al (2003) Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model. J Pharm Pharm Sci 6:1-12
    • (2003) J Pharm Pharm Sci , vol.6 , pp. 1-12
    • Pachot, J.I.1    Botham, R.P.2    Haegele, K.D.3
  • 99
    • 0035262142 scopus 로고    scopus 로고
    • Uptake and intracellular activity of ketolide HMR 3647 in human phagocytic and non-phagocytic cells
    • Pascual A, Ballesta S, Garcia I et al (2001) Uptake and intracellular activity of ketolide HMR 3647 in human phagocytic and non-phagocytic cells. Clin Microbiol Infect 7:65-69
    • (2001) Clin Microbiol Infect , vol.7 , pp. 65-69
    • Pascual, A.1    Ballesta, S.2    Garcia, I.3
  • 100
    • 0026740641 scopus 로고
    • Clarithromycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential
    • Peters DH, Clissold S.P. (1992) Clarithromycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential. Drugs 44:117-164
    • (1992) Drugs , vol.44 , pp. 117-164
    • Peters, D.H.1    Clissold, S.P.2
  • 101
    • 0037416983 scopus 로고    scopus 로고
    • ABT-773: Pharmacokinetics and interactions with ranitidine and sucralfate
    • Pletz MW, Preechachatchaval V, Bulitta J et al (2003) ABT-773: pharmacokinetics and interactions with ranitidine and sucralfate. Antimicrob Agents Chemother 47:1129-1131
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1129-1131
    • Pletz, M.W.1    Preechachatchaval, V.2    Bulitta, J.3
  • 102
    • 0023483280 scopus 로고
    • Roxithromycin: A pharmacokinetic review of a macrolide
    • Puri SK, Lassman H.B. (1987) Roxithromycin: a pharmacokinetic review of a macrolide. J Antimicrob Chemother 20(Suppl B):89-100
    • (1987) J Antimicrob Chemother , vol.20 , pp. 89-100
    • Puri, S.K.1    Lassman, H.B.2
  • 103
    • 0030956116 scopus 로고    scopus 로고
    • Intrapulmonary steady-state concentrations of clarithromycin and azithromycin in healthy adult volunteers
    • Rodvold KA, Gotfried MH, Danziger LH et al (1997) Intrapulmonary steady-state concentrations of clarithromycin and azithromycin in healthy adult volunteers. Antimicrob Agents Chemother 41:1399-1402
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1399-1402
    • Rodvold, K.A.1    Gotfried, M.H.2    Danziger, L.H.3
  • 104
    • 84866337951 scopus 로고    scopus 로고
    • Comparison of plasma, epithelial lining fluid, and alveolar macrophage concentrations of solithromycin (CEM-101) in healthy adult subjects
    • Rodvold KA, Gotfried MH, Still JG et al (2012) Comparison of plasma, epithelial lining fluid, and alveolar macrophage concentrations of solithromycin (CEM-101) in healthy adult subjects. Antimicrob Agents Chemother 56(10):5076-5081
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.10 , pp. 5076-5081
    • Rodvold, K.A.1    Gotfried, M.H.2    Still, J.G.3
  • 105
    • 0019858719 scopus 로고
    • Acyl derivatives of 16-membered macrolides. I. Synthesis and biological properties of 3"-O-propionylleucomycin A5 (TMS-19-Q)
    • Sakakibara H, Okekawa O, Fujiwara T et al (1981) Acyl derivatives of 16-membered macrolides. I. Synthesis and biological properties of 3"-O-propionylleucomycin A5 (TMS-19-Q). J Antibiot (Tokyo) 34:1001-1010
    • (1981) J Antibiot (Tokyo) , vol.34 , pp. 1001-1010
    • Sakakibara, H.1    Okekawa, O.2    Fujiwara, T.3
  • 106
    • 66149121800 scopus 로고    scopus 로고
    • Intracellular activity of antibiotics against staphylococcus aureus in a mouse peritonitis model
    • Sandberg A, Hessler JH, Skov RL et al (2009) Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. Antimicrob Agents Chemother 53:1874-1883
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 1874-1883
    • Sandberg, A.1    Hessler, J.H.2    Skov, R.L.3
  • 107
    • 13644281331 scopus 로고
    • Tissue-directed pharmacokinetics
    • Schentag JJ, Ballow C.H. (1991) Tissue-directed pharmacokinetics. Am J Med 91:5S-11S
    • (1991) Am J Med , vol.91 , pp. 5S-11S
    • Schentag, J.J.1    Ballow, C.H.2
  • 108
    • 0038101671 scopus 로고    scopus 로고
    • Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by listeria monocytogenes or staphylococcus aureus
    • Seral C, Carryn S, Tulkens PM et al (2003a) Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus. J Antimicrob Chemother 51:1167-1173
    • (2003) J Antimicrob Chemother , vol.51 , pp. 1167-1173
    • Seral, C.1    Carryn, S.2    Tulkens, P.M.3
  • 109
    • 0037417076 scopus 로고    scopus 로고
    • Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages
    • Seral C, Michot JM, Chanteux H et al (2003b) Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages. Antimicrob Agents Chemother 47: 1047-1051
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1047-1051
    • Seral, C.1    Michot, J.M.2    Chanteux, H.3
  • 110
    • 33645833853 scopus 로고    scopus 로고
    • Drug interactions during therapy with three major groups of antimicrobial agents
    • Shakeri-Nejad K., Stahlmann R. (2006) Drug interactions during therapy with three major groups of antimicrobial agents. Expert Opin Pharmacother 7:639-651
    • (2006) Expert Opin Pharmacother , vol.7 , pp. 639-651
    • Shakeri-Nejad, K.1    Stahlmann, R.2
  • 111
    • 24344466640 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of telithromycin, the first ketolide antibacterial
    • Shi J, Montay G, Bhargava V.O. (2005) Clinical pharmacokinetics of telithromycin, the first ketolide antibacterial. Clin Pharmacokinet 44:915-934
    • (2005) Clin Pharmacokinet , vol.44 , pp. 915-934
    • Shi, J.1    Montay, G.2    Bhargava, V.O.3
  • 112
    • 39549115019 scopus 로고    scopus 로고
    • Macrolide antibiotics as immunomodulatory medications: Proposed mechanisms of action
    • Shinkai M, Henke MO, Rubin B.K. (2008) Macrolide antibiotics as immunomodulatory medications: proposed mechanisms of action. Pharmacol Ther 117:393-405
    • (2008) Pharmacol Ther , vol.117 , pp. 393-405
    • Shinkai, M.1    Henke, M.O.2    Rubin, B.K.3
  • 113
    • 79955542813 scopus 로고    scopus 로고
    • Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects
    • Still JG, Schranz J, Degenhardt TP et al (2011) Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects. Antimicrob Agents Chemother 55:1997-2003
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1997-2003
    • Still, J.G.1    Schranz, J.2    Degenhardt, T.P.3
  • 114
    • 34047240096 scopus 로고    scopus 로고
    • Azithromycin extended release: A review of its use in the treatment of acute bacterial sinusitis and community-acquired pneumonia in the US
    • Swainston HT, Keam S.J. (2007) Azithromycin extended release: a review of its use in the treatment of acute bacterial sinusitis and community-acquired pneumonia in the US. Drugs 67:773-792
    • (2007) Drugs , vol.67 , pp. 773-792
    • Swainston, H.T.1    Keam, S.J.2
  • 115
    • 0036235528 scopus 로고    scopus 로고
    • Pharmacodynamic assessment of clarithromycin in a murine model of pneumococcal pneumonia
    • Tessier PR, Kim MK, Zhou W et al (2002) Pharmacodynamic assessment of clarithromycin in a murine model of pneumococcal pneumonia. Antimicrob Agents Chemother 46:1425-1434
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1425-1434
    • Tessier, P.R.1    Kim, M.K.2    Zhou, W.3
  • 116
    • 11244342348 scopus 로고    scopus 로고
    • Pharmacodynamic profile of telithromycin against macrolide- and fluoroquinolone-resistant streptococcus pneumoniae in a neutropenic mouse thigh model
    • Tessier PR, Mattoes HM, Dandekar PK et al (2005) Pharmacodynamic profile of telithromycin against macrolide- and fluoroquinolone-resistant Streptococcus pneumoniae in a neutropenic mouse thigh model. Antimicrob Agents Chemother 49:188-194
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 188-194
    • Tessier, P.R.1    Mattoes, H.M.2    Dandekar, P.K.3
  • 117
    • 77953195425 scopus 로고    scopus 로고
    • Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections
    • Togami K, Chono S, Seki T et al (2010a) Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections. Drug Dev Ind Pharm 36:861-866
    • (2010) Drug Dev Ind Pharm , vol.36 , pp. 861-866
    • Togami, K.1    Chono, S.2    Seki, T.3
  • 118
    • 77949533787 scopus 로고    scopus 로고
    • Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages
    • Togami K, Chono S, Seki T et al (2010b) Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages. J Pharm Pharmacol 62:71-75
    • (2010) J Pharm Pharmacol , vol.62 , pp. 71-75
    • Togami, K.1    Chono, S.2    Seki, T.3
  • 119
    • 67349120012 scopus 로고    scopus 로고
    • Multiple-dose pharmacokinetics of telithromycin in peripheral soft tissues
    • Traunmuller F, Fille M, Thallinger C et al (2009) Multiple-dose pharmacokinetics of telithromycin in peripheral soft tissues. Int J Antimicrob Agents 34:72-75
    • (2009) Int J Antimicrob Agents , vol.34 , pp. 72-75
    • Traunmuller, F.1    Fille, M.2    Thallinger, C.3
  • 120
    • 33846915413 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic modeling of in vitro activity of azithromycin against four different bacterial strains
    • Treyaprasert W, Schmidt S, Rand KH et al (2007) Pharmacokinetic/pharmacodynamic modeling of in vitro activity of azithromycin against four different bacterial strains. Int J Antimicrob Agents 29:263-270
    • (2007) Int J Antimicrob Agents , vol.29 , pp. 263-270
    • Treyaprasert, W.1    Schmidt, S.2    Rand, K.H.3
  • 121
    • 33645026902 scopus 로고    scopus 로고
    • Cellular pharmacodynamics and pharmacokinetics of antibiotics: Current views and perspectives
    • Van Bambeke F., Barcia-Macay M, Lemaire S et al (2006) Cellular pharmacodynamics and pharmacokinetics of antibiotics: current views and perspectives. Curr Opin Drug Discov Devel 9:218-230
    • (2006) Curr Opin Drug Discov Devel , vol.9 , pp. 218-230
    • Van Bambeke, F.1    Barcia-Macay, M.2    Lemaire, S.3
  • 122
    • 39049097113 scopus 로고    scopus 로고
    • Ketolides: Pharmacological profile and rational positioning in the treatment of respiratory tract infections
    • Van Bambeke F., Harms JM, Van Laethem Y et al (2008) Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections. Expert Opin Pharmacother 9:267-283
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 267-283
    • Van Bambeke, F.1    Harms, J.M.2    Van Laethem, Y.3
  • 123
    • 0031879813 scopus 로고    scopus 로고
    • Interactions between HMR 3647, a new ketolide, and human polymorphonuclear neutrophils
    • Vazifeh D, Preira A, Bryskier A et al (1998) Interactions between HMR 3647, a new ketolide, and human polymorphonuclear neutrophils. Antimicrob Agents Chemother 42:1944-1951
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1944-1951
    • Vazifeh, D.1    Preira, A.2    Bryskier, A.3
  • 124
    • 0027420830 scopus 로고
    • Correlation between macrolide lung pharmacokinetics and therapeutic efficacy in a mouse model of pneumococcal pneumonia
    • Veber B, Vallee E, Desmonts JM et al (1993) Correlation between macrolide lung pharmacokinetics and therapeutic efficacy in a mouse model of pneumococcal pneumonia. J Antimicrob Chemother 32:473-482
    • (1993) J Antimicrob Chemother , vol.32 , pp. 473-482
    • Veber, B.1    Vallee, E.2    Desmonts, J.M.3
  • 126
    • 0023791140 scopus 로고
    • Toxicity, uptake, and subcellular distribution in rat hepatocytes of roxithromycin, a new semisynthetic macrolide, and erythromycin base
    • Villa P, Sassella D, Corada M et al (1988) Toxicity, uptake, and subcellular distribution in rat hepatocytes of roxithromycin, a new semisynthetic macrolide, and erythromycin base. Antimicrob Agents Chemother 32:1541-1546
    • (1988) Antimicrob Agents Chemother , vol.32 , pp. 1541-1546
    • Villa, P.1    Sassella, D.2    Corada, M.3
  • 127
    • 10044284273 scopus 로고    scopus 로고
    • Synthesis of novel 6,11-O-bridged bicyclic ketolides via a palladium-catalyzed bis-allylation
    • Wang G, Niu D, Qiu YL et al (2004) Synthesis of novel 6,11-O-bridged bicyclic ketolides via a palladium-catalyzed bis-allylation. Org Lett 6:4455-4458
    • (2004) Org Lett , vol.6 , pp. 4455-4458
    • Wang, G.1    Niu, D.2    Qiu, Y.L.3
  • 128
    • 0030743728 scopus 로고    scopus 로고
    • Intracellular activity of azithromycin against mycobacterium avium complex in human macrophages
    • Wildfeuer A, Haberreiter A. (1997) Intracellular activity of azithromycin against Mycobacterium avium complex in human macrophages. Arzneimittelforschung 47:866-868
    • (1997) Arzneimittelforschung , vol.47 , pp. 866-868
    • Wildfeuer, A.1    Haberreiter, A.2
  • 130
    • 57449102073 scopus 로고    scopus 로고
    • Ketolides - The modern relatives of macrolides: The pharmacokinetic perspective
    • Zeitlinger M, Wagner CC, Heinisch B. (2009) Ketolides-the modern relatives of macrolides: the pharmacokinetic perspective. Clin Pharmacokinet 48:23-38
    • (2009) Clin Pharmacokinet , vol.48 , pp. 23-38
    • Zeitlinger, M.1    Wagner, C.C.2    Heinisch, B.3
  • 131
    • 0035059952 scopus 로고    scopus 로고
    • Review of macrolides and ketolides: Focus on respiratory tract infections
    • Zhanel GG, Dueck M, Hoban DJ et al (2001) Review of macrolides and ketolides: focus on respiratory tract infections. Drugs 61:443-498
    • (2001) Drugs , vol.61 , pp. 443-498
    • Zhanel, G.G.1    Dueck, M.2    Hoban, D.J.3
  • 132
    • 0036343455 scopus 로고    scopus 로고
    • The ketolides: A critical review
    • Zhanel GG, Walters M, Noreddin A et al (2002) The ketolides: a critical review. Drugs 62: 1771-1804
    • (2002) Drugs , vol.62 , pp. 1771-1804
    • Zhanel, G.G.1    Walters, M.2    Noreddin, A.3
  • 133
    • 0037925150 scopus 로고    scopus 로고
    • Pharmacodynamic activity of azithromycin against macrolide-susceptible and - Resistant streptococcus pneumoniae simulating clinically achievable free serum, epithelial lining fluid and middle ear fluid concentrations
    • Zhanel GG, DeCorby M, Noreddin A et al (2003) Pharmacodynamic activity of azithromycin against macrolide-susceptible and - resistant Streptococcus pneumoniae simulating clinically achievable free serum, epithelial lining fluid and middle ear fluid concentrations. J Antimicrob Chemother 52:83-88
    • (2003) J Antimicrob Chemother , vol.52 , pp. 83-88
    • Zhanel, G.G.1    DeCorby, M.2    Noreddin, A.3
  • 134
    • 18244382544 scopus 로고    scopus 로고
    • Pharmacodynamic activity of telithromycin at simulated clinically achievable free-drug concentrations in serum and epithelial lining fluid against efflux (mefE)-producing macrolide-resistant streptococcus pneumoniae for which telithromycin MICs vary
    • Zhanel GG, Johanson C, Laing N et al (2005) Pharmacodynamic activity of telithromycin at simulated clinically achievable free-drug concentrations in serum and epithelial lining fluid against efflux (mefE)-producing macrolide-resistant Streptococcus pneumoniae for which telithromycin MICs vary. Antimicrob Agents Chemother 49:1943-1948
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 1943-1948
    • Zhanel, G.G.1    Johanson, C.2    Laing, N.3
  • 135
    • 77954309361 scopus 로고    scopus 로고
    • High azithromycin loading powders for inhalation and their in vivo evaluation in rats
    • Zhang Y, Wang X, Lin X et al (2010) High azithromycin loading powders for inhalation and their in vivo evaluation in rats. Int J Pharm 395:205-214
    • (2010) Int J Pharm , vol.395 , pp. 205-214
    • Zhang, Y.1    Wang, X.2    Lin, X.3


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