Integrated approaches for analyzing U1-70K cleavage in Alzheimers disease

Journal of Proteome Research

Volumn 13, Issue 11, 2014, Pages 4526-4534

  Bai, Bing ^a   Chen, Ping Chung ^a   Hales, Chadwick M ^c   Wu, Zhiping ^a   Pagala, Vishwajeeth ^b   High, Anthony A ^b   Levey, Allan I ^c   Lah, James J ^c   Peng, Junmin ^a,b  

^a Departments of Neurobiology   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

Alzheimers disease; LC MS MS; mass spectrometry; neurodegenerative disease; proteolytic cleavage; proteomics; RNA splicing; stable isotope labeling; U1 snRNP; U1 70K

Indexed keywords

STABLE ISOTOPE; PEPTIDE FRAGMENT; SMALL NUCLEAR RIBONUCLEOPROTEIN; SNRNP70 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; GENETIC TRANSFECTION; HEK293 CELL LINE; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROPHILICITY; LIQUID CHROMATOGRAPHY; NERVE CELL; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; RNA CLEAVAGE; RNA SPLICING; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING; ANIMAL; CYTOLOGY; METABOLISM; PATHOPHYSIOLOGY;

ALZHEIMER DISEASE; ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, LIQUID; HIPPOCAMPUS; HUMANS; NEURONS; PEPTIDE FRAGMENTS; PROTEOLYSIS; RATS; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR; TANDEM MASS SPECTROMETRY;

EID: 84908888137     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5003593     Document Type: Article

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