Molecular dynamics simulations identify time scale of conformational changes responsible for conformational selection in molecular recognition of HIV-1 transactivation responsive RNA

Journal of the American Chemical Society

Volumn 136, Issue 44, 2014, Pages 15631-15637

  Musiani, Francesco ^a,b,c   Rossetti, Giulia ^c   Capece, Luciana ^d   Gerger, Thomas Martin ^c   Micheletti, Cristian ^a   Varani, Gabriele ^e   Carloni, Paolo ^c  

^a SISSA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

^d INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; CONFORMATIONS; RNA; TAR; TIME MEASUREMENT;

CONFORMATIONAL CHANGE; CONFORMATIONAL ENSEMBLE; CONFORMATIONAL FLUCTUATIONS; CONFORMATIONAL SELECTION; EXPERIMENTAL TECHNIQUES; MOLECULAR DYNAMICS SIMULATIONS; MOLECULAR SIMULATIONS; REGULATORY ELEMENTS;

MOLECULAR DYNAMICS;

RNA; TRANSACTIVATION RESPONSIVE RNA; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CONFORMATION; CONFORMATIONAL SELECTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; IONIC STRENGTH; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; TRANSACTIVATION; CHEMISTRY; GENETICS; TRANSCRIPTION INITIATION;

HIV-1; MOLECULAR DYNAMICS SIMULATION; NUCLEIC ACID CONFORMATION; RNA, VIRAL; TRANSCRIPTIONAL ACTIVATION;

EID: 84908658478     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja507812v     Document Type: Article

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