A small-molecule probe induces a conformation in HIV TAR RNA capable of binding drug-like fragments

Journal of Molecular Biology

Volumn 410, Issue 5, 2011, Pages 984-996

  Davidson, Amy ^a   Begley, Darren W ^a,b   Lau, Carmen ^a   Varani, Gabriele ^a,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Emerald BioStructures   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

fragment based ligand design; HIV; RNA; TAR; Tat

Indexed keywords

RNA; TRANSACTIVATOR PROTEIN;

ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; MOLECULAR DOCKING; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN RNA BINDING; RNA STRUCTURE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 79960361918     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.03.039     Document Type: Article

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