Taenia solium tapeworms synthesize corticosteroids and sex steroids in vitro

General and Comparative Endocrinology

Volumn 205, Issue , 2014, Pages 62-67

  Valdez, R A ^a   Jimenez P ^a   Fernandez Presas A M ^b   Aguilar, L ^b   Willms, K ^b   Romano, M C ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Corticosteroid synthesis; Helmynths; Parasites; Sex steroid synthesis; Taenia solium tapeworms; Taeniids

Indexed keywords

ANDROSTENEDIONE; CORTICOSTEROID; CORTICOSTERONE; CORTODOXONE; DEOXYCORTICOSTERONE; ESTRADIOL; ESTRONE; HORMONE PRECURSOR; HYDROCORTISONE; PROGESTERONE; SEX HORMONE; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; TRITIUM;

ADULT; ANIMAL EXPERIMENT; ARTICLE; ENZYME ACTIVITY; ENZYME MECHANISM; HOST PARASITE INTERACTION; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; LARVAL STAGE; LIMIT OF DETECTION; NONHUMAN; PAEDOGENESIS; PROTEIN EXPRESSION; STEROIDOGENESIS; TAENIA SOLIUM; THIN LAYER CHROMATOGRAPHY; ANIMAL; BIOSYNTHESIS; HAMSTER; HUMAN; METABOLISM;

ADRENAL CORTEX HORMONES; ANDROSTENEDIONE; ANIMALS; CHROMATOGRAPHY, THIN LAYER; CRICETINAE; GONADAL STEROID HORMONES; HUMANS; PROGESTERONE; TAENIA SOLIUM; TESTOSTERONE; TRITIUM;

EID: 84908621859     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2014.04.014     Document Type: Article

References (44)

1. Aceves-Ramos A., Valdez R.A., Gaona B., Willms K., Romano M.C. Steroid synthesis by Taenia crassiceps WFU cysticerci is regulated by enzyme inhibitors. Gen. Comp. Endocrinol. 2013, 188:212-217.
2. Aceves-Ramos A., de la Torre P., Hinojosa L., Ponce A., García-Villegas R., Laclette J.P., Bobes R.J., Romano M.C. Cloning, characterization and functional expression of Taenia solium 17 beta-hydroxysteroid dehydrogenase. Gen. Comp. Endocrinol. 2014, 203:186-192.
3. Bridghamm J.T., Carroll S.M., Thornton J.W. Evolution of hormone receptor complexity by molecular exploitation. Science 2006, 312:97-101.
4. Brookes J.C., Galigniana M.D., Harker A.H., Stoneham A.M., Vinson G.P. System among the corticosteroids: specificity and molecular dynamics. J. R. Soc. Interface 2012, 9(66):43-53.
5. Cárdenas G., Valdez R., Saenz B., Botasso O., Fragoso G., Sciutto E., Romano M.C., Fleury A. Impact of Taenia solium neurocysticercosis upon endocrine status and its relation with immunoinflammatory parameters. Int. J. Parasitol. 2012, 42:171-176.
6. Campbell C.M., Foster A., Jalabert B., Truscott B. Identification and quantification of steroids in the serum of rainbow trout during spermiation and oocyte maturation. J. Endocrinol. 1980, 85:371-378.
7. Close D.A., Yun S., Mac Cormick S., Wildbill A.J., Li W. 11-Deoxycortisol is a corticosteroid in the lamprey. Gen. Comp. Endocrinol. 2010, 107:13942-13947.
8. Conley A.J., Bird I.M. The role of cytochrome P450 17 alpha-hydroxylase and 3 beta-hydroxysteroid dehydrogenase in the integration of gonadal and adrenal steroidogenesis via the delta 5 and delta 4 pathways of steroidogenesis in mammals. Biol. Reprod. 1997, 56:789-799.
9. Davies E., MacKenzie S.M. Extra adrenal production of corticosteroids. Clin. Exp. Pharmacol. Physiol. 2003, 30:437-445.
10. Fernández Presas A.M., Willms K., Romano M.C. The key steroidogenic enzyme 3β-hydroxysteroid dehydrogenase is present in the strobilae and larvae of Taenia solium and T. crassiceps WFU strain. Parasitol. Res. 2008, 103:847-852.
11. Gómez Y., Valdéz R.A., Larralde C., Romano M.C. Sex steroids and parasitism: Taenia crassiceps cysticercus metabolizes exogenous androstenedione to testosterone in vitro. J. Steroid Biochem. Mol. Biol. 2000, 74:143-147.
12. Hannen R.F., Michael A.E., Jaulim A., Bhogal R., Burrin J.M., Philpott M.P. Steroid synthesis by primary human keratinocytes; implications for skin disease. Biochem. Biophys. Res. Commun. 2011, 404:62-67.
13. Jiménez P., Valdéz R.A., Romano M.C. Metabolism of steroid hormones by Taenia solium and Taenia crassiceps cysticerci. J. Steroid Biochem. Mol. Biol. 2006, 99:203-208.
14. Kiilerich P., Tipsmark C.K., Borski R.J., Madsen S.S. Differential effects of cortisol and 11-deoxycorticosterone on ion transport protein mRNA levels in gills of two euryhaline teleosts, Mozambique tilapia and striped bass. J. Endocrinol. 2011, 209:115-126.
15. Kumar S., Hedges S.B. A molecular timescale for vertebrate evolution. Nature 1998, 392:917-920.
16. Labrie F., Simard J., Luu-The V., Pelletier G., Belghmi K., Belanger A. Structure, regulation and role of 3 beta-hydroxysteroid dehydrogenase, 17 beta-hydroxysteroid dehydrogenase and aromatase enzymes in the formation of sex steroids in classical and peripheral intracrine tissues. Baillieres Clin. Endocrinol. Metab. 1994, 8:451-474.
17. Mc Cormick S.D. Endocrine control of osmoregulation in teleost fish. Am. Zool. 2001, 41:781-794.
18. Merchant M.T., Corella C., Willms K. Autoradiographic analysis of the germinative tissue in evaginated Taenia solium metacestodes. J. Parasitol. 1997, 83:363-367.
19. Michael A.E., Cooke B.A. A working hypothesis for the regulation of steroidogenesis and germ cell development in the gonads by glucocorticoids and 11β-hydroxysteroid dehydrogenase (11βHSD). Mol. Cell. Endocrinol. 1994, 100:55-63.
20. Milla S., Terrien X., Sturm A., Ibrahim F., Giton F., Fiet J., Prunet P., Le Gac F. Plasma 11-deoxycorticosterone (DOC) and mineralocorticoid receptor testicular expression during rainbow trout Oncorhynchus mykiss spermiation: implication with 17alpha, 20beta-dihydroprogesterone on the milt fluidity. Reprod. Biol. Endocrinol. 2008, 6:6-19.
21. Mommsen T.P., Vijayan M.M., Moon T.W. Cortisol in teleosts: Dynamics mechanism of action and metabolic regulation. Rev. Fish Biol. Fisher. 1999, 9:211-268.
22. Penning T.M. Molecular endocrinology of hydroxysteroid dehydrogenases. Endocr. Rev. 1997, 18:281-305.
23. Payne A.H., Hales D.B. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocrine Rev. 2004, 25:947-970.
24. Pazirandeh, Xue Y., Rafter I., Sjoväl J., Jondal M., Okret S. Paracrine glucocorticoid activity produced by thymic epithelial cells. FASEB J. 1999, 13:893-901.
25. Provost P.R., Tremblay Y. Genes involved in the adrenal pathway of glucocorticoid synthesis are transiently expressed in the developing lung. Endocrinology 2005, 146:2239-2245.
26. Reyes-Hernandez J.L., Leung G., McKay D.M. Cestode regulation of inflammation and inflammatory diseases. Int. J. Parasitol. 2013, 43:233-243.
27. Romano M.C., Valdéz R.A., Cartas A.L., Gómez Y., Larralde C. Steroid hormone production by parasites: the case of Taenia crassiceps and Taenia solium cysticerci. J. Steroid Biochem. Mol. Biol. 2003, 85:221-225.
28. Romano M.C., Valdéz R.A., Hinojosa L., Gómez Y., Jiménez P. Are hormones relevant for the search and design of anti-parasitic drugs?. Curr. Top. Med. Chem. 2008, 8:408-414.
29. Sapolsky R.M., Romero L.M., Munck A.U. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory and preparative actions. Endocr. Rev. 2000, 21:55-89.
30. Simard J., Rickkets M.L., Gingras S., Soucy P., Feltus F.A., Melner F.H. Molecular biology of the 3beta-hydroxysteroid dehydrogenase delta 5/delta 4 isomerase gene family. Endocr. Rev. 2005, 26:525-582.
31. Stocco D.M., Clark B.J. Regulation of the acute production of steroids in steroidogenic cells. Endocr. Rev. 1996, 17:221-244.
32. Stolte E.H., Kemenade B.M., Savelkoul H.F.J., Flik G. Evolution of glucocorticoid receptors with different glucocorticoid sensitivity. J. Endocrinol. 2006, 190:17-28.
33. Sturm B.J., Bury N., Dengreville L., Fagart J., Flouriot G., Rafestin-Oblin M.E., Prunet P. 11-Deoxycorticosterone is a potent agonist of the rainbow trout (Oncorhynchus mykiss) mineralocorticoid receptor. Endocrinology 2005, 146:47-55.
34. Terrazas L.I. Susceptibility and resistance to cysticercosis. Curr. Top. Med. Chem. 2008, 8:408-414.
35. Thornton J.W. Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:5671-5676.
36. Vacchio M.S., Papadopoulos V., Ashwell J.D. Steroid production in the thymus: implications for thymocyte selection. J. Exp. Med. 1994, 179:1835-1846.
37. Valdéz R.A., Jiménez P., Cartas A.L., Gómez Y., Romano M.C. Taenia solium cysticerci synthesize androgens and estrogens in vitro. Parasitol. Res. 2006, 98:472-476.
38. Valdéz R.A., Hinojosa L., Gómez Y., Willms K., Romano M.C. Taenia crassiceps WFU cysticerci synthesize corticosteroids in vitro: metyrapone regulates the production. Gen. Comp. Endocrinol. 2012, 176:409-414.
39. Varsamos S., Nebel C., Charmantier G. Ontogeny of osmoregulation in postembryonic fish: a review. Comp. Biochem. Physiol. A 2005, 141:401-429.
40. Vinson G.P. The mislabelling of deoxycorticosterone: making sense of corticosteroid structure and function. J. Endocrinol 2011, 211:3-16.
41. Wada H. Glucocorticoids: mediators of vertebrate ontogenic transitions. Gen. Comp. Endocrinol. 2008, 156:441-453.
42. Willms K., Shoemaker Ch.B., Skelly P.J., Landa A. Cloning and expression of a Na+, K+-ATPase-subunit from Taenia solium (TNaK1). Mol. Biochem. Parasitol. 2004, 138:79-82.
43. White A.C. Neurocysticercosis: updates on epidemiology, pathogenesis, diagnosis and management. Annu. Rev. Med. 2000, 51:187-206.
44. Willms K., Caro J.A., Robert L. Ultrastructure of spermatogonia and spermatocyte lobules in Taenia solium strobilae (Cestoda, Cyclophyllidea, Taeniidae) from golden hamsters. Parasitol. Res. 2003, 90:479-488.