-
1
-
-
45249123879
-
Structural diversity of organic chemistry. A scaffold analysis of the CAS Registry
-
doi:10.1021/jo8001276
-
Lipkus, A. H., Yuan, Q., Lucas, K. A., Funk, S. A., Bartelt III, W. F., Schenck, R. J. & Trippe, A. J. 2008 Structural diversity of organic chemistry. A scaffold analysis of the CAS Registry. J. Org. Chem. 73, 4443-4451. (doi:10.1021/jo8001276)
-
(2008)
J. Org. Chem.
, vol.73
, pp. 4443-4451
-
-
Lipkus, A.H.1
Yuan, Q.2
Lucas, K.A.3
Funk, S.A.4
Bartelt III, W.F.5
Schenck, R.J.6
Trippe, A.J.7
-
2
-
-
59649085308
-
The adrenal cortex and life
-
doi:10.1016/j.mce.2008.09.008
-
Vinson, G. P. 2009 The adrenal cortex and life. Mol. Cell. Endocrinol. 300, 2-6. (doi:10.1016/j.mce.2008.09.008)
-
(2009)
Mol. Cell. Endocrinol.
, vol.300
, pp. 2-6
-
-
Vinson, G.P.1
-
3
-
-
14544281944
-
Colocalization of mineralocorticoid receptor and glucocorticoid receptor in the hippocampus and hypothalamus
-
doi:10.1016/j.neures.2004.12.013
-
Han, F., Ozawa, H., Matsuda, K., Nishi, M. & Kawata, M. 2005 Colocalization of mineralocorticoid receptor and glucocorticoid receptor in the hippocampus and hypothalamus. Neurosci. Res. 51, 371-381. (doi:10.1016/j.neures. 2004.12.013)
-
(2005)
Neurosci. Res.
, vol.51
, pp. 371-381
-
-
Han, F.1
Ozawa, H.2
Matsuda, K.3
Nishi, M.4
Kawata, M.5
-
4
-
-
15044365996
-
The human mineralocorticoid receptor only partially differentiates between different ligands after expression in fission yeast
-
doi:10.1016/j.femsyr.2004.12.007
-
Bureik, M., Bruck, N., Hubel, K. & Bernhardt, R. 2005 The human mineralocorticoid receptor only partially differentiates between different ligands after expression in fission yeast. FEMS Yeast Res. 5, 627-633. (doi:10.1016/j.femsyr.2004.12.007)
-
(2005)
FEMS Yeast Res.
, vol.5
, pp. 627-633
-
-
Bureik, M.1
Bruck, N.2
Hubel, K.3
Bernhardt, R.4
-
5
-
-
0034112386
-
Specificity in mineralocorticoid versus glucocorticoid action
-
doi:10.1046/j.1523-1755.2000.00959.x
-
Fuller, P. J., Lim-Tio, S. S. & Brennan, F. E. 2000 Specificity in mineralocorticoid versus glucocorticoid action. Kidney Int. 57, 1256-1264. (doi:10.1046/j.1523-1755.2000.00959.x)
-
(2000)
Kidney Int.
, vol.57
, pp. 1256-1264
-
-
Fuller, P.J.1
Lim-Tio, S.S.2
Brennan, F.E.3
-
6
-
-
34249950662
-
Dynamics of glucocorticoid receptor and mineralocorticoid receptor: Implications from live cell imaging studies
-
doi:10.1159/000101917
-
Nishi, M. & Kawata, M. 2007 Dynamics of glucocorticoid receptor and mineralocorticoid receptor: implications from live cell imaging studies. Neuroendocrinology 85, 186-192. (doi:10.1159/000101917)
-
(2007)
Neuroendocrinology
, vol.85
, pp. 186-192
-
-
Nishi, M.1
Kawata, M.2
-
7
-
-
2342544131
-
Towards selectively modulating mineralocorticoid receptor function: Lessons from other systems
-
doi:10.1016/j.mce.2003.10.044
-
Baxter, J. D., Funder, J. W., Apriletti, J. W. & Webb, P. 2004 Towards selectively modulating mineralocorticoid receptor function: lessons from other systems. Mol. Cell. Endocrinol. 217, 151-165. (doi:10.1016/j.mce.2003.10. 044)
-
(2004)
Mol. Cell. Endocrinol.
, vol.217
, pp. 151-165
-
-
Baxter, J.D.1
Funder, J.W.2
Apriletti, J.W.3
Webb, P.4
-
8
-
-
0033406694
-
Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors
-
doi:10.1016/S0014-5793(99)01667-1
-
Hellal-Levy, C., Couette, B., Fagart, J., Souque, A., Gomez-Sanchez, C. & Rafestin-Oblin, M. 1999 Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors. FEBS Lett. 464, 9-13. (doi:10.1016/S0014-5793(99)01667-1)
-
(1999)
FEBS Lett.
, vol.464
, pp. 9-13
-
-
Hellal-Levy, C.1
Couette, B.2
Fagart, J.3
Souque, A.4
Gomez-Sanchez, C.5
Rafestin-Oblin, M.6
-
9
-
-
0032977322
-
The type I and type II 11 beta-hydroxysteroid dehydrogenase enzymes
-
doi:10.1016/S0960-0760(99)00074-6
-
Krozowski, Z. et al. 1999 The type I and type II 11 beta-hydroxysteroid dehydrogenase enzymes. J. Steroid Biochem. Mol. Biol. 69, 391-401. (doi:10.1016/S0960-0760(99)00074-6)
-
(1999)
J. Steroid Biochem. Mol. Biol.
, vol.69
, pp. 391-401
-
-
Krozowski, Z.1
-
10
-
-
0344740887
-
Cortisol and the renal handling of electrolytes: Role in glucocorticoid-induced hypertension and bone disease
-
doi:10.1016/S1521-690X(03)00053-8
-
Ferrari, P. 2003 Cortisol and the renal handling of electrolytes: role in glucocorticoid-induced hypertension and bone disease. Best Pract. Res. Clin. Endocrinol. Metab. 17, 575-589. (doi:10.1016/S1521-690X(03)00053-8)
-
(2003)
Best Pract. Res. Clin. Endocrinol. Metab.
, vol.17
, pp. 575-589
-
-
Ferrari, P.1
-
11
-
-
0027516933
-
Aldosterone action
-
doi:10.1146/annurev.ph.55.030193.000555
-
Funder, J. W. 1993 Aldosterone action. Annu. Rev. Physiol. 55, 115-130. (doi:10.1146/annurev.ph.55.030193.000555)
-
(1993)
Annu. Rev. Physiol.
, vol.55
, pp. 115-130
-
-
Funder, J.W.1
-
12
-
-
21244485815
-
Mineralocorticoid receptors: Distribution and activation
-
doi:10.1007/s10741-005-2344-2
-
Funder, J. W. 2005 Mineralocorticoid receptors: distribution and activation. Heart Fail. Rev. 10, 15-22. (doi:10.1007/s10741-005-2344-2)
-
(2005)
Heart Fail. Rev.
, vol.10
, pp. 15-22
-
-
Funder, J.W.1
-
13
-
-
0029065303
-
Glucocorticoid receptor, mineralocorticoid receptors, 11 beta-hydroxysteroid dehydrogenase-1 and -2 expression in rat brain and kidney: In situ studies
-
doi:10.1016/0303-7207(95)03559-P
-
Roland, B. L., Krozowski, Z. S. & Funder, J. W. 1995 Glucocorticoid receptor, mineralocorticoid receptors, 11 beta-hydroxysteroid dehydrogenase-1 and -2 expression in rat brain and kidney: in situ studies. Mol. Cell. Endocrinol. 111, R1-R7. (doi:10.1016/0303-7207(95)03559-P)
-
(1995)
Mol. Cell. Endocrinol.
, vol.111
-
-
Roland, B.L.1
Krozowski, Z.S.2
Funder, J.W.3
-
14
-
-
34548042789
-
Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious rats
-
doi:10.1152/ajprenal.00484.2006
-
Usa, K., Singh, R. J., Netzel, B. C., Liu, Y., Raff, H. & Liang, M. 2007 Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious rats. Am. J. Physiol. Renal Physiol. 293, F186-F192. (doi:10.1152/ajprenal. 00484.2006)
-
(2007)
Am. J. Physiol. Renal Physiol.
, vol.293
-
-
Usa, K.1
Singh, R.J.2
Netzel, B.C.3
Liu, Y.4
Raff, H.5
Liang, M.6
-
15
-
-
2342586714
-
Molecular mechanism of activation and nuclear translocation of the mineralocorticoid receptor upon binding of pregnanesteroids
-
doi:10.1016/j.mce.2003.10.041
-
Galigniana, M. D., Piwien Pilipuk, G., Kanelakis, K. C., Burton, G. & Lantos, C. P. 2004 Molecular mechanism of activation and nuclear translocation of the mineralocorticoid receptor upon binding of pregnanesteroids. Mol. Cell. Endocrinol. 217, 167-179. (doi:10.1016/j.mce.2003.10.041)
-
(2004)
Mol. Cell. Endocrinol.
, vol.217
, pp. 167-179
-
-
Galigniana, M.D.1
Piwien Pilipuk, G.2
Kanelakis, K.C.3
Burton, G.4
Lantos, C.P.5
-
16
-
-
24744451821
-
A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor
-
doi:10.1074/jbc.M504098200
-
Bledsoe, R. K. et al. 2005 A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor. J. Biol. Chem. 280, 31 283-31 293. (doi:10.1074/jbc.M504098200)
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31283-31293
-
-
Bledsoe, R.K.1
-
17
-
-
18444405534
-
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
-
doi:10.1016/S0092-8674(02)00817-6
-
Bledsoe, R. K. et al. 2002 Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition. Cell 110, 93-105. (doi:10.1016/S0092-8674(02)00817-6)
-
(2002)
Cell
, vol.110
, pp. 93-105
-
-
Bledsoe, R.K.1
-
18
-
-
37349085453
-
A flexible approach to induced fit docking
-
doi:10.1021/jm070593p
-
Nabuurs, S. B., Wagener, M. & de Vlieg, J. 2007 A flexible approach to induced fit docking. J. Med. Chem. 50, 6507-6518. (doi:10.1021/jm070593p)
-
(2007)
J. Med. Chem.
, vol.50
, pp. 6507-6518
-
-
Nabuurs, S.B.1
Wagener, M.2
De Vlieg, J.3
-
19
-
-
0017100804
-
Crystal structure of steroids: Molecular conformation and biological function
-
Duax, W. L., Weeks, C. M. & Rohrer, D. C. 1976 Crystal structure of steroids: molecular conformation and biological function. Recent Progr. Hormone Res. 32, 81-116.
-
(1976)
Recent Progr. Hormone Res.
, vol.32
, pp. 81-116
-
-
Duax, W.L.1
Weeks, C.M.2
Rohrer, D.C.3
-
20
-
-
57349172278
-
Odour character differences for enantiomers correlate with molecular flexibility
-
doi:10.1098/rsif.2008.0165
-
Brookes, J. C., Horsfield, A. P. & Stoneham, A. M. 2009 Odour character differences for enantiomers correlate with molecular flexibility. J. R. Soc. Interface 6, 75-86. (doi:10.1098/rsif.2008.0165)
-
(2009)
J. R. Soc. Interface
, vol.6
, pp. 75-86
-
-
Brookes, J.C.1
Horsfield, A.P.2
Stoneham, A.M.3
-
21
-
-
0020615392
-
Structural and configurational dependence of the sensory process in steroids
-
Ohloff, G., Maurer, B., Winter, B. & Giersch, W. 1983 Structural and configurational dependence of the sensory process. Helvetica Chim. Acta 66, 192-217. (Pubitemid 13130972)
-
(1983)
Helvetica Chimica Acta
, vol.66
, Issue.1
, pp. 192-217
-
-
Ohloff, G.1
Maurer, B.2
Winter, B.3
Giersch, W.4
-
22
-
-
0842341771
-
A new general quantum mechanical molecular model
-
Dewar, M. J., Zoebisch, E. G., Healy, E. F. & Stewart, J. J. 1985 A new general quantum mechanical molecular model. J. Am. Chem. Soc. 107, 3902.
-
(1985)
J. Am. Chem. Soc.
, vol.107
, pp. 3902
-
-
Dewar, M.J.1
Zoebisch, E.G.2
Healy, E.F.3
Stewart, J.J.4
-
23
-
-
0000189651
-
Density-functional thermochemistry. III. The role of exact exchange
-
doi:10.1063/1.464913
-
Becke, A. D. 1993 Density-functional thermochemistry. III. The role of exact exchange. J. Chem. Phys. 98, 5648-5652. (doi:10.1063/1.464913)
-
(1993)
J. Chem. Phys.
, vol.98
, pp. 5648-5652
-
-
Becke, A.D.1
-
25
-
-
9144240095
-
DREIDING: A generic force field for molecular simulations
-
doi:10.1021/j100389a010
-
Mayo, S. L., Olafson, B. D. & Goddard III, W. A. 1990 DREIDING: a generic force field for molecular simulations. J. Phys. Chem. 94, 8897-8909. (doi:10.1021/j100389a010)
-
(1990)
J. Phys. Chem.
, vol.94
, pp. 8897-8909
-
-
Mayo, S.L.1
Olafson, B.D.2
Goddard III, W.A.3
-
26
-
-
2942532422
-
Development and testing of a general amber force field
-
doi:10.1002/jcc.20035
-
Wang, J., Wolf, R. M., Caldwell, J. W., Kollman, P. A. & Case, D. A. 2004 Development and testing of a general amber force field. J. Comput. Chem. 25, 1157-1174. (doi:10.1002/jcc.20035)
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1157-1174
-
-
Wang, J.1
Wolf, R.M.2
Caldwell, J.W.3
Kollman, P.A.4
Case, D.A.5
-
27
-
-
0000121981
-
Preliminary results of an electron diffraction reinvestigation of cyclobutane and cyclopentane
-
Almenningen, A., Bastiansen, O. & Skancke, P. N. 1961 Preliminary results of an electron diffraction reinvestigation of cyclobutane and cyclopentane. Acta Chem. Scand. 15, 711.
-
(1961)
Acta Chem. Scand.
, vol.15
, pp. 711
-
-
Almenningen, A.1
Bastiansen, O.2
Skancke, P.N.3
-
28
-
-
0004117577
-
-
London, UK: John Wiley & Sons
-
Eliel, E. L., Allinger, N. L., Angyal, S. J. & Morrison, G. A. 1965 Conformational analysis. London, UK: John Wiley & Sons.
-
(1965)
Conformational Analysis
-
-
Eliel, E.L.1
Allinger, N.L.2
Angyal, S.J.3
Morrison, G.A.4
-
30
-
-
0000375207
-
Adrenocorticotrophic hormone; adrenocortical steroids and their synthetic analogues; inhibitors of adrenocortical steroid biosynthesis
-
(eds A. G. Gilman, L. S. Goodman, T. W. Rall & F. Murad). New York, NY: Macmillan
-
Haynes, R. C. & Murad, F. 1985 Adrenocorticotrophic hormone; adrenocortical steroids and their synthetic analogues; inhibitors of adrenocortical steroid biosynthesis. In The pharmacological basis of therapeutics (eds A. G. Gilman, L. S. Goodman, T. W. Rall & F. Murad). New York, NY: Macmillan.
-
(1985)
The Pharmacological Basis of Therapeutics
-
-
Haynes, R.C.1
Murad, F.2
-
31
-
-
78651051155
-
The present status of aldosterone in clinical medicine
-
Genest, J. 1955 The present status of aldosterone in clinical medicine. Can. Med. Assoc. J. 73, 876-883.
-
(1955)
Can. Med. Assoc. J.
, vol.73
, pp. 876-883
-
-
Genest, J.1
-
32
-
-
0000528032
-
The adrenal cortex
-
ed. J. D. Wilson, Philadelphia, PA: W.B. Saunders
-
Orth, D. N. & Kovacs, W. J. 1998 The adrenal cortex. In Williams' textbook of endocrinology (ed. J. D. Wilson), pp. 517-664. Philadelphia, PA: W.B. Saunders.
-
(1998)
Williams' Textbook of Endocrinology
, pp. 517-664
-
-
Orth, D.N.1
Kovacs, W.J.2
-
33
-
-
0346908835
-
Influence of corticosteroids on protein and carbohydrate metabolism
-
(eds H. Blaschko, A. D. Smith & G. Sayers), Washington, DC: American Physiological Society
-
Steele, R. 1975 Influence of corticosteroids on protein and carbohydrate metabolism. In Handbook of physiology (eds H. Blaschko, A. D. Smith & G. Sayers), pp. 135-167. Washington, DC: American Physiological Society.
-
(1975)
Handbook of Physiology
, pp. 135-167
-
-
Steele, R.1
-
34
-
-
0033602480
-
The glucocorticoid properties of the synthetic steroid pregna-1,4-diene-11beta-ol-3,20-dione (deltaHOP) are not entirely correlated with the steroid binding to the glucocorticoid receptor
-
doi:10.1016/S0303-7207(98)00205-6
-
Vicent, G. P., Pecci, A., Ghini, A. A., Piwien-Pilipuk, G., Veleiro, A. S., Burton, G., Lantos, C. P. & Galigniana, M. D. 1999 The glucocorticoid properties of the synthetic steroid pregna-1,4-diene-11beta-ol-3,20-dione (deltaHOP) are not entirely correlated with the steroid binding to the glucocorticoid receptor. Mol. Cell. Endocrinol. 149, 207-219. (doi:10.1016/S0303-7207(98)00205-6)
-
(1999)
Mol. Cell. Endocrinol.
, vol.149
, pp. 207-219
-
-
Vicent, G.P.1
Pecci, A.2
Ghini, A.A.3
Piwien-Pilipuk, G.4
Veleiro, A.S.5
Burton, G.6
Lantos, C.P.7
Galigniana, M.D.8
-
35
-
-
0002639757
-
A method for the colorimetric estimation of glycogen with iodine
-
Krisman, C. R. 1962 A method for the colorimetric estimation of glycogen with iodine. Anal. Biochem. 4, 17-23.
-
(1962)
Anal. Biochem.
, vol.4
, pp. 17-23
-
-
Krisman, C.R.1
-
36
-
-
0030952348
-
Features of the shuttle pair 11 beta-hydroxyprogesterone-11- ketoprogesterone
-
Galigniana, M. D., Vicent, G. P., Burton, G. & Lantos, C. P. 1997 Features of the shuttle pair 11 beta-hydroxyprogesterone-11-ketoprogesterone. Steroids 62, 358-364.
-
(1997)
Steroids
, vol.62
, pp. 358-364
-
-
Galigniana, M.D.1
Vicent, G.P.2
Burton, G.3
Lantos, C.P.4
-
37
-
-
37049025017
-
Differential recruitment of tetratricorpeptide repeat domain immunophilins to the mineralocorticoid receptor influences both heat-shock protein 90-dependent retrotransport and hormone-dependent transcriptional activity
-
doi:10.1021/bi701372c
-
Gallo, L. I., Ghini, A. A., Pilipuk, G. P. & Galigniana, M. D. 2007 Differential recruitment of tetratricorpeptide repeat domain immunophilins to the mineralocorticoid receptor influences both heat-shock protein 90-dependent retrotransport and hormone-dependent transcriptional activity. Biochemistry 46, 14 044-14 057. (doi:10.1021/bi701372c)
-
(2007)
Biochemistry
, vol.46
, pp. 14044-14057
-
-
Gallo, L.I.1
Ghini, A.A.2
Pilipuk, G.P.3
Galigniana, M.D.4
-
38
-
-
59649088671
-
The chemistry of the hormones
-
Selye, H. & Jensen, H. 1946 The chemistry of the hormones. Ann. Rev. Biochem. 15, 347-360.
-
(1946)
Ann. Rev. Biochem.
, vol.15
, pp. 347-360
-
-
Selye, H.1
Jensen, H.2
-
39
-
-
60849127882
-
Enhanced cortisol production rates, free cortisol, and 11beta-HSD-1 expression correlate with visceral fat and insulin resistance in men: Effect of weight loss
-
doi:10.1152/ajpendo.90769.2008
-
Purnell, J. Q., Kahn, S. E., Samuels, M. H., Brandon, D., Loriaux, D. L. & Brunzell, J. D. 2009 Enhanced cortisol production rates, free cortisol, and 11beta-HSD-1 expression correlate with visceral fat and insulin resistance in men: effect of weight loss. Am J Physiol Endocrinol Metab 296, E351-E357. (doi:10.1152/ajpendo.90769.2008)
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Purnell, J.Q.1
Kahn, S.E.2
Samuels, M.H.3
Brandon, D.4
Loriaux, D.L.5
Brunzell, J.D.6
-
40
-
-
0034126395
-
Interactions of mineralocorticoids and glucocorticoids in epithelial target tissues
-
doi:10.1046/j.1523-1755.2000.00977.x
-
Morris, D. J., Souness, G. W., Brem, A. S. & Oblin, M. E. 2000 Interactions of mineralocorticoids and glucocorticoids in epithelial target tissues. Kidney Int. 57, 1370-1373. (doi:10.1046/j.1523-1755.2000.00977.x)
-
(2000)
Kidney Int.
, vol.57
, pp. 1370-1373
-
-
Morris, D.J.1
Souness, G.W.2
Brem, A.S.3
Oblin, M.E.4
-
41
-
-
84954981008
-
The general adaptation syndrome and the diseases of adaptation
-
Selye, H. 1946 The general adaptation syndrome and the diseases of adaptation. J. Clin. Endocrinol. Metab. 6, 117-230.
-
(1946)
J. Clin. Endocrinol. Metab.
, vol.6
, pp. 117-230
-
-
Selye, H.1
-
42
-
-
53849096731
-
Testing geometrical discrimination within an enzyme active site: Constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole
-
doi:10.1021/ja803928m
-
Sigala, P. A., Kraut, D. A., Caaveiro, J. M., Pybus, B., Ruben, E. A., Ringe, D., Petsko, G. A. & Herschlag, D. 2008 Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole. J. Am. Chem. Soc. 130, 13 696-13 708. (doi:10.1021/ja803928m)
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 13696-13708
-
-
Sigala, P.A.1
Kraut, D.A.2
Caaveiro, J.M.3
Pybus, B.4
Ruben, E.A.5
Ringe, D.6
Petsko, G.A.7
Herschlag, D.8
-
43
-
-
70450281537
-
The principles of conformational analysis
-
Amsterdam, The Netherlands: Elsevier
-
Barton, D. H. 1972 The principles of conformational analysis. In Nobel Lectures, 1963-1970, pp. 298-311. Amsterdam, The Netherlands: Elsevier.
-
(1972)
Nobel Lectures, 1963-1970
, pp. 298-311
-
-
Barton, D.H.1
|