Glycoborinine induces apoptosis through mitochondrial pathway in HepG2 cells

Journal of Asian Natural Products Research

Volumn 16, Issue 10, 2014, Pages 991-999

  Yang, Hua ^a   Tian, Shi Ting ^a   Wu, Rui Yun ^a   Chen, Yu ^a   Mei, Zhi Nan ^a   Wang, Chao Yuan ^a   Yang, Guang Zhong ^a  

^a SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

anti tumor activity; glycoborinine; mitochondrial apoptotic pathway

Indexed keywords

ALKALOID DERIVATIVE; ANTINEOPLASTIC AGENT; CASPASE 3; CYTOCHROME C; GLYCOBORININE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 3; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 5,5',6,6'-TETRACHLORO-1,1',3,3'-TETRAETHYLBENZIMIDAZOLOCARBOCYANINE; BENZIMIDAZOLE DERIVATIVE; CARBAZOLE DERIVATIVE; CARBOCYANINE; PROTEIN BCL 2;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CHROMATIN; CHROMATIN CONDENSATION; CONTROLLED STUDY; FLOW CYTOMETRY; HEPG2 CELL LINE; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CLEAVAGE; WESTERN BLOTTING; CHEMICAL STRUCTURE; CHEMISTRY; DIAGNOSTIC USE; DOSE RESPONSE; DRUG EFFECTS; HUMAN; IC50; LIVER TUMOR; METABOLISM;

APOPTOSIS; BENZIMIDAZOLES; CARBAZOLES; CARBOCYANINES; CASPASE 3; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR STRUCTURE; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES;

EID: 84908606328     PISSN: 10286020     EISSN: 14772213     Source Type: Journal    
DOI: 10.1080/10286020.2014.918961     Document Type: Article

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