Olaquindox induces apoptosis through the mitochondrial pathway in HepG2 cells

Toxicology

Volumn 285, Issue 3, 2011, Pages 104-113

  Zou, Jiajie ^a,b   Chen, Qian ^a,c   Jin, Xi ^a,d   Tang, Shusheng ^a   Chen, Kaipao ^a,b   Zhang, Ting ^a   Xiao, Xilong ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b JOINN Laboratories   (China)

^c INSTITUTE OF ZOOLOGY   (China)

^d BEIJING NORMAL UNIVERSITY   (China)

Author keywords

Apoptosis; Bcl 2; Mitochondrial pathway; Olaquindox; P53

Indexed keywords

CASPASE 3; CASPASE 9; CELL NUCLEUS DNA; CYTOCHROME C; MITOCHONDRIAL DNA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OLAQUINDOX; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; UPREGULATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CASPASES; CELL CYCLE; CYTOCHROMES C; DNA DAMAGE; HEP G2 CELLS; HUMANS; IN SITU NICK-END LABELING; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; POLY(ADP-RIBOSE) POLYMERASES; POLYMERASE CHAIN REACTION; QUINOXALINES; TUMOR SUPPRESSOR PROTEIN P53;

SUIDAE;

EID: 79957808725     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.04.010     Document Type: Article

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