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Volumn 47, Issue 5, 2014, Pages 435-447

In vitro combined treatment with cetuximab and trastuzumab inhibits growth of colon cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MESSENGER RNA; TRASTUZUMAB; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN; MONOCLONAL ANTIBODY;

EID: 84908606093     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/cpr.12125     Document Type: Article
Times cited : (27)

References (60)
  • 2
    • 34548277030 scopus 로고    scopus 로고
    • EUROCARE Working group: survival for eight major cancers and all cancers combined for European adults diagnosed in 1995-99: results of the EUROCARE-4 study
    • Berrino F, De Angelis R, Sant M, Rosso S, Bielska-Lasota M, Coebergh JW et al. (2007) EUROCARE Working group: survival for eight major cancers and all cancers combined for European adults diagnosed in 1995-99: results of the EUROCARE-4 study. Lancet Oncol. 8, 773-783.
    • (2007) Lancet Oncol. , vol.8 , pp. 773-783
    • Berrino, F.1    De Angelis, R.2    Sant, M.3    Rosso, S.4    Bielska-Lasota, M.5    Coebergh, J.W.6
  • 3
    • 2342530749 scopus 로고    scopus 로고
    • EUROCARE-3 summary cancer survival in Europe at the end of the 20th century
    • EUROCARE Working Group
    • Coleman MP, Gatta G, Verdecchia A, Estève J, Sant M, Storm H et al.; EUROCARE Working Group (2003) EUROCARE-3 summary cancer survival in Europe at the end of the 20th century. Ann. Oncol. 14(Suppl 5), v128-v149.
    • (2003) Ann. Oncol. , vol.14 , pp. v128-v149
    • Coleman, M.P.1    Gatta, G.2    Verdecchia, A.3    Estève, J.4    Sant, M.5    Storm, H.6
  • 4
    • 0034959016 scopus 로고    scopus 로고
    • The Type 1 growth factor receptors and their ligands considered as a complex system
    • Gullick WJ (2001) The Type 1 growth factor receptors and their ligands considered as a complex system. Endocr. Relat. Cancer 8, 75-82.
    • (2001) Endocr. Relat. Cancer , vol.8 , pp. 75-82
    • Gullick, W.J.1
  • 5
    • 70349223044 scopus 로고    scopus 로고
    • The epidermal growth factor system of ligands and receptors in cancer
    • Gullick WJ (2009) The epidermal growth factor system of ligands and receptors in cancer. Eur. J. Cancer 45(Suppl 1), 205-210.
    • (2009) Eur. J. Cancer , vol.45 , pp. 205-210
    • Gullick, W.J.1
  • 7
    • 75549083827 scopus 로고    scopus 로고
    • EGFR signaling and drug discovery
    • Lurje G, Lenz HJ (2009) EGFR signaling and drug discovery. Oncology 77, 400-410.
    • (2009) Oncology , vol.77 , pp. 400-410
    • Lurje, G.1    Lenz, H.J.2
  • 8
    • 0036362181 scopus 로고    scopus 로고
    • Why the epidermal growth factor receptor? The rationale for cancer therapy
    • Baselga J (2002) Why the epidermal growth factor receptor? The rationale for cancer therapy. Oncologist 7(Suppl 4), 2-8.
    • (2002) Oncologist , vol.7 , pp. 2-8
    • Baselga, J.1
  • 9
    • 17444380497 scopus 로고    scopus 로고
    • EGF receptor inhibition: attacks on multiple fronts
    • Hubbard SR (2005) EGF receptor inhibition: attacks on multiple fronts. Cancer Cell 7, 287-288.
    • (2005) Cancer Cell , vol.7 , pp. 287-288
    • Hubbard, S.R.1
  • 10
    • 27744607673 scopus 로고    scopus 로고
    • Cetuximab: an epidermal growth factor receptor monoclonal antibody for the treatment of colorectal cancer
    • Wong SF (2005) Cetuximab: an epidermal growth factor receptor monoclonal antibody for the treatment of colorectal cancer. Clin. Ther. 27, 684-694.
    • (2005) Clin. Ther. , vol.27 , pp. 684-694
    • Wong, S.F.1
  • 11
    • 33749316418 scopus 로고    scopus 로고
    • The epidermal growth factor receptor pathway: a model for targeted therapy
    • Scaltriti M, Baselga J (2006) The epidermal growth factor receptor pathway: a model for targeted therapy. Clin. Cancer Res. 12, 5268-5272.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 5268-5272
    • Scaltriti, M.1    Baselga, J.2
  • 12
    • 0031684721 scopus 로고    scopus 로고
    • The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy
    • Ross JS, Fletcher JA (1998) The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Oncologist 3, 237-252.
    • (1998) Oncologist , vol.3 , pp. 237-252
    • Ross, J.S.1    Fletcher, J.A.2
  • 13
    • 1242274464 scopus 로고    scopus 로고
    • Effects of trastuzumab on epidermal growth factor receptor-dependent and-independent human colon cancer cells
    • Kuwada SK, Scaife CL, Kuang J, Li X, Wong RF, Florell SR et al. (2004) Effects of trastuzumab on epidermal growth factor receptor-dependent and-independent human colon cancer cells. Int. J. Cancer 109, 291-301.
    • (2004) Int. J. Cancer , vol.109 , pp. 291-301
    • Kuwada, S.K.1    Scaife, C.L.2    Kuang, J.3    Li, X.4    Wong, R.F.5    Florell, S.R.6
  • 14
    • 0034929997 scopus 로고    scopus 로고
    • The HER-2/neu oncogene in tumors of the gastrointestinal tract
    • Ross JS, McKenna BJ (2001) The HER-2/neu oncogene in tumors of the gastrointestinal tract. Cancer Invest. 19, 554-568.
    • (2001) Cancer Invest. , vol.19 , pp. 554-568
    • Ross, J.S.1    McKenna, B.J.2
  • 15
    • 77957931103 scopus 로고    scopus 로고
    • Clinico-pathological and prognostic significance of p53, Bcl-2 and Her-2/neu protein markers in colorectal cancer using tissue microarray
    • Ismail HM, El-Baradie M, Moneer M, Khorshid O, Touny A (2007) Clinico-pathological and prognostic significance of p53, Bcl-2 and Her-2/neu protein markers in colorectal cancer using tissue microarray. J. Egypt. Natl. Canc. Inst. 19, 3-14.
    • (2007) J. Egypt. Natl. Canc. Inst. , vol.19 , pp. 3-14
    • Ismail, H.M.1    El-Baradie, M.2    Moneer, M.3    Khorshid, O.4    Touny, A.5
  • 16
    • 84856196387 scopus 로고    scopus 로고
    • Expression of Her-2/neu in colon carcinoma and its correlation with the histological grades and the lymph nodes status
    • Gill MK, Manjari M, Jain K, Kaur T (2011) Expression of Her-2/neu in colon carcinoma and its correlation with the histological grades and the lymph nodes status. JCDR 5, 1564-1568.
    • (2011) JCDR , vol.5 , pp. 1564-1568
    • Gill, M.K.1    Manjari, M.2    Jain, K.3    Kaur, T.4
  • 20
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, Khayat D, Bleiberg H, Santoro A et al. (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N. Engl. J. Med. 351, 337-345.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3    Khayat, D.4    Bleiberg, H.5    Santoro, A.6
  • 24
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signalling
    • Graus-Porta D, Beerli RR, Daly JM, Hynes NE (1997) ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signalling. EMBO J. 16, 1647-1655.
    • (1997) EMBO J. , vol.16 , pp. 1647-1655
    • Graus-Porta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.E.4
  • 25
    • 0038718522 scopus 로고    scopus 로고
    • Developing inhibitors of the epidermal growth factor receptor for cancer treatment
    • Grunwald V, Hidalgo M (2003) Developing inhibitors of the epidermal growth factor receptor for cancer treatment. J. Natl. Cancer Inst. 95, 4851-4867.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 4851-4867
    • Grunwald, V.1    Hidalgo, M.2
  • 26
    • 13844306484 scopus 로고    scopus 로고
    • Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy
    • Friedman LM, Rinon A, Schechter B, Lyass L, Lavi S, Bacus SS et al. (2005) Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy. Proc. Natl. Acad. Sci. USA 102, 1915-1920.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 1915-1920
    • Friedman, L.M.1    Rinon, A.2    Schechter, B.3    Lyass, L.4    Lavi, S.5    Bacus, S.S.6
  • 27
    • 62549147841 scopus 로고    scopus 로고
    • Persistent elimination of ErbB-2/HER2-overexpressing tumors using combinations of monoclonal antibodies: relevance of receptor endocytosis
    • Ben-Kasus T, Schechter B, Lavi S, Yarden Y, Sela M (2009) Persistent elimination of ErbB-2/HER2-overexpressing tumors using combinations of monoclonal antibodies: relevance of receptor endocytosis. Proc. Natl. Acad. Sci. USA 106, 3294-3299.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3294-3299
    • Ben-Kasus, T.1    Schechter, B.2    Lavi, S.3    Yarden, Y.4    Sela, M.5
  • 28
    • 0017412603 scopus 로고
    • One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice
    • Fogh J, Fogh JM, Orfeo T (1977) One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J. Natl. Cancer Inst. 59, 221-226.
    • (1977) J. Natl. Cancer Inst. , vol.59 , pp. 221-226
    • Fogh, J.1    Fogh, J.M.2    Orfeo, T.3
  • 30
  • 31
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: the complexity of targeted inhibitors
    • Hynes NE, Lane HA (2005) ERBB receptors and cancer: the complexity of targeted inhibitors. Nat. Rev. Cancer 5, 341-354.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 32
    • 63749086305 scopus 로고    scopus 로고
    • ErbB receptors and signaling pathways in cancer
    • Hynes NE, MacDonald G (2009) ErbB receptors and signaling pathways in cancer. Curr. Opin. Cell Biol. 21, 177-184.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 177-184
    • Hynes, N.E.1    MacDonald, G.2
  • 34
    • 1642421130 scopus 로고    scopus 로고
    • Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment
    • Normanno N, Bianco C, De Luca A, Maiello MR, Salomon DS (2003) Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr. Relat. Cancer 10, 1-21.
    • (2003) Endocr. Relat. Cancer , vol.10 , pp. 1-21
    • Normanno, N.1    Bianco, C.2    De Luca, A.3    Maiello, M.R.4    Salomon, D.S.5
  • 36
    • 31544457665 scopus 로고    scopus 로고
    • Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis
    • Zhou Y, Li S, Hu YP, Wang J, Hauser J, Conway AN et al. (2006) Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis. Cancer Res. 66, 404-411.
    • (2006) Cancer Res. , vol.66 , pp. 404-411
    • Zhou, Y.1    Li, S.2    Hu, Y.P.3    Wang, J.4    Hauser, J.5    Conway, A.N.6
  • 37
    • 21344457447 scopus 로고    scopus 로고
    • Synergy of epidermal growth factor receptor kinase inhibitor AG1478 and ErbB2 kinase inhibitor AG879 in human colon carcinoma cells is associated with induction of apoptosis
    • Zhou Y, Brattain MG (2005) Synergy of epidermal growth factor receptor kinase inhibitor AG1478 and ErbB2 kinase inhibitor AG879 in human colon carcinoma cells is associated with induction of apoptosis. Cancer Res. 65, 5848-5856.
    • (2005) Cancer Res. , vol.65 , pp. 5848-5856
    • Zhou, Y.1    Brattain, M.G.2
  • 39
    • 0032934041 scopus 로고    scopus 로고
    • Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis
    • Damstrup L, Kuwada SK, Dempsey PJ, Brown CL, Hawkey CJ, Poulsen HS et al. (1999) Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis. Br. J. Cancer 80, 1012-1019.
    • (1999) Br. J. Cancer , vol.80 , pp. 1012-1019
    • Damstrup, L.1    Kuwada, S.K.2    Dempsey, P.J.3    Brown, C.L.4    Hawkey, C.J.5    Poulsen, H.S.6
  • 40
    • 0033404509 scopus 로고    scopus 로고
    • The dynamic expression of the epidermal growth factor receptor and epidermal growth factor ligand family in a differentiating intestinal epithelial cell line
    • Kuwada SK, Li XF, Damstrup L, Dempsey PJ, Coffey RJ, Wiley HS (1999) The dynamic expression of the epidermal growth factor receptor and epidermal growth factor ligand family in a differentiating intestinal epithelial cell line. Growth Factors 17, 139-153.
    • (1999) Growth Factors , vol.17 , pp. 139-153
    • Kuwada, S.K.1    Li, X.F.2    Damstrup, L.3    Dempsey, P.J.4    Coffey, R.J.5    Wiley, H.S.6
  • 41
    • 40949135397 scopus 로고    scopus 로고
    • PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab
    • Jhawer M, Goel S, Wilson AJ, Montagna C, Ling YH, Byun DS et al. (2008) PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab. Cancer Res. 68, 1953-1961.
    • (2008) Cancer Res. , vol.68 , pp. 1953-1961
    • Jhawer, M.1    Goel, S.2    Wilson, A.J.3    Montagna, C.4    Ling, Y.H.5    Byun, D.S.6
  • 42
    • 51349159152 scopus 로고    scopus 로고
    • Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines
    • Solmi R, Lauriola M, Francesconi M, Martini D, Voltattorni M, Ceccarelli C et al. (2008) Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines. BMC Cancer 8, 227.
    • (2008) BMC Cancer , vol.8 , pp. 227
    • Solmi, R.1    Lauriola, M.2    Francesconi, M.3    Martini, D.4    Voltattorni, M.5    Ceccarelli, C.6
  • 43
    • 0028081735 scopus 로고
    • Regulation of Caco-2 cell proliferation by basolateral membrane epidermal growth factor receptors
    • Bishop WP, Wen JT (1994) Regulation of Caco-2 cell proliferation by basolateral membrane epidermal growth factor receptors. Am. J. Physiol. 267, G892-G900.
    • (1994) Am. J. Physiol. , vol.267 , pp. G892-G900
    • Bishop, W.P.1    Wen, J.T.2
  • 44
    • 0026650727 scopus 로고
    • Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-α. Characterization of mammary gland and skin proliferation
    • Halter SA, Dempsey PJ, Matsui Y, Stokes MK, Graves-Deal R, Hogan BLM et al. (1992) Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-α. Characterization of mammary gland and skin proliferation. Am. J. Pathol. 140, 1131-1146.
    • (1992) Am. J. Pathol. , vol.140 , pp. 1131-1146
    • Halter, S.A.1    Dempsey, P.J.2    Matsui, Y.3    Stokes, M.K.4    Graves-Deal, R.5    Hogan, B.L.M.6
  • 46
    • 0026720594 scopus 로고
    • Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon
    • Johnson GR, Saeki T, Gordon AW, Shoyab M, Salomon DS, Stromberg K (1992) Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon. J. Cell Biol. 118, 741-751.
    • (1992) J. Cell Biol. , vol.118 , pp. 741-751
    • Johnson, G.R.1    Saeki, T.2    Gordon, A.W.3    Shoyab, M.4    Salomon, D.S.5    Stromberg, K.6
  • 47
    • 0026779893 scopus 로고
    • Colorectum cell-derived growth factor (CRDGF) is homologous to amphiregulin, a member of the epidermal growth factor family
    • Culouscou JM, Remacle-Bonnet M, Carlton GW, Plowman GD, Shoyab M (1992) Colorectum cell-derived growth factor (CRDGF) is homologous to amphiregulin, a member of the epidermal growth factor family. Growth Factors 7, 195-205.
    • (1992) Growth Factors , vol.7 , pp. 195-205
    • Culouscou, J.M.1    Remacle-Bonnet, M.2    Carlton, G.W.3    Plowman, G.D.4    Shoyab, M.5
  • 48
    • 33645749886 scopus 로고    scopus 로고
    • In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR
    • Balin-Gauthier D, Delord JP, Rochaix P, Mallard V, Thomas F, Hennebelle I et al. (2006) In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR. Cancer Chemother. Pharmacol. 57, 709-718.
    • (2006) Cancer Chemother. Pharmacol. , vol.57 , pp. 709-718
    • Balin-Gauthier, D.1    Delord, J.P.2    Rochaix, P.3    Mallard, V.4    Thomas, F.5    Hennebelle, I.6
  • 49
    • 33745698049 scopus 로고    scopus 로고
    • Molecular cytogenetics: genomic imbalances in colorectal cancer and their clinical impact
    • Grade M, Becker H, Liersch T, Ried T, Ghadimi BM (2006) Molecular cytogenetics: genomic imbalances in colorectal cancer and their clinical impact. Cell Oncol. 28, 71-84.
    • (2006) Cell Oncol. , vol.28 , pp. 71-84
    • Grade, M.1    Becker, H.2    Liersch, T.3    Ried, T.4    Ghadimi, B.M.5
  • 50
    • 78651519477 scopus 로고    scopus 로고
    • Recent advances in molecular diagnostics of colorectal cancer by genomic arrays: proposal for a procedural shift in biological sampling and pathological report
    • Castorina S, Barresi V, Luca T, Privitera G, Musso N, Capizzi C et al. (2010) Recent advances in molecular diagnostics of colorectal cancer by genomic arrays: proposal for a procedural shift in biological sampling and pathological report. Ital. J. Anat. Embryol. 115, 39-45.
    • (2010) Ital. J. Anat. Embryol. , vol.115 , pp. 39-45
    • Castorina, S.1    Barresi, V.2    Luca, T.3    Privitera, G.4    Musso, N.5    Capizzi, C.6
  • 53
    • 33747860634 scopus 로고    scopus 로고
    • Treatment of HNSCC cell lines with the EGFR-specific inhibitor cetuximab (Erbitux) results in paradox phosphorylation of tyrosine 1173 in the receptor
    • Mandic R, Rodgarkia-Dara CJ, Zhu L, Folz BJ, Bette M, Weihe E et al. (2006) Treatment of HNSCC cell lines with the EGFR-specific inhibitor cetuximab (Erbitux) results in paradox phosphorylation of tyrosine 1173 in the receptor. FEBS Lett. 580, 4793-5000.
    • (2006) FEBS Lett. , vol.580 , pp. 4793-5000
    • Mandic, R.1    Rodgarkia-Dara, C.J.2    Zhu, L.3    Folz, B.J.4    Bette, M.5    Weihe, E.6
  • 54
    • 33750103211 scopus 로고    scopus 로고
    • Anti-EGFR therapies: clinical experience in colorectal, lung, and head and neck cancers
    • Vokes EE, Chu E (2006) Anti-EGFR therapies: clinical experience in colorectal, lung, and head and neck cancers. Oncology (Williston Park) 20(5 Suppl 2), 15-25.
    • (2006) Oncology (Williston Park) , vol.20 , Issue.5 , pp. 15-25
    • Vokes, E.E.1    Chu, E.2
  • 55
    • 16244400108 scopus 로고    scopus 로고
    • Cetuximab: an epidermal growth factor receptor chemeric human-murine monoclonal antibody
    • Harding J, Burtness B (2005) Cetuximab: an epidermal growth factor receptor chemeric human-murine monoclonal antibody. Drugs Today (Barc.) 41, 107-127.
    • (2005) Drugs Today (Barc.) , vol.41 , pp. 107-127
    • Harding, J.1    Burtness, B.2
  • 57
    • 0034234854 scopus 로고    scopus 로고
    • Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2
    • Klapper LN, Waterman H, Sela M, Yarden Y (2000) Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2. Cancer Res. 60, 3384-3388.
    • (2000) Cancer Res. , vol.60 , pp. 3384-3388
    • Klapper, L.N.1    Waterman, H.2    Sela, M.3    Yarden, Y.4
  • 58
    • 60149109196 scopus 로고    scopus 로고
    • Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity
    • Scaltriti M, Verma C, Guzman M, Jimenez J, Parra JL, Pedersen K et al. (2009) Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity. Oncogene 28, 803-814.
    • (2009) Oncogene , vol.28 , pp. 803-814
    • Scaltriti, M.1    Verma, C.2    Guzman, M.3    Jimenez, J.4    Parra, J.L.5    Pedersen, K.6


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