The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi's sarcoma cells in vitro

European Journal of Pharmacology

Volumn 616, Issue 1-3, 2009, Pages 16-21

  Luca, Tonia ^a,b   Di Benedetto, Giulia ^a   Scuderi, Mariagrazia Rita ^a   Palumbo, Marco ^a   Clementi, Silvia ^a   Bernardini, Renato ^a   Cantarella, Giuseppina ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b Fondazione Mediterranea GB Morgagni   (Italy)

Author keywords

Cannabinoid antagonist; Cell death; Kaposi's sarcoma; Signal transduction

Indexed keywords

1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; CASPASE 3; CASPASE 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N (2 CHLOROETHYL) 5,8,11,14 EICOSATETRAENAMIDE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BENZOXAZINE DERIVATIVE; CANNABINOID; CASPASE; MITOGEN ACTIVATED PROTEIN KINASE; MORPHOLINE DERIVATIVE; NAPHTHALENE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; KAPOSI SARCOMA; PRIORITY JOURNAL; SARCOMA CELL; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENZYME SPECIFICITY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PREGNANCY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZOXAZINES; CANNABINOIDS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; NAPHTHALENES; PREGNANCY; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; SARCOMA, KAPOSI; SUBSTRATE SPECIFICITY;

EID: 67651100560     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.06.004     Document Type: Article

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