TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion

Molecular Biology of the Cell

Volumn 25, Issue 22, 2014, Pages 3528-3540

  Osborne, Lukas D ^a   Li, George Z ^b   How, Tam ^b   O'Brien, E Tim ^a   Blobe, Gerard C ^b   Superfine, Richard ^a   Mythreye, Karthikeyan ^c  

^a The University of North Carolina at Chapel Hill   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GEF H1 PROTEIN; INTEGRIN; LARG PROTEIN; PROTEASOME; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG; ARHGEF12 PROTEIN, HUMAN; ARHGEF2 PROTEIN, HUMAN;

ARTICLE; CELL CULTURE; CELL INVASION; CELL STIFFNESS; CELLULAR PARAMETERS; EPITHELIAL MESENCHYMAL TRANSITION; GENETIC TRANSFECTION; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REGULATORY MECHANISM; ANIMAL; BIOMECHANICS; CELL ADHESION; CELL MOTION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MECHANOTRANSDUCTION; METABOLISM; MOUSE; PRESSURE; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; BIOMECHANICAL PHENOMENA; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTEGRINS; MECHANOTRANSDUCTION, CELLULAR; MICE; NEOPLASM INVASIVENESS; PRESSURE; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84908576798     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E14-05-1015     Document Type: Article

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